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carotid endarterectomy(CEA)

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https://www.readbyqxmd.com/read/29452833/endothelial-vascular-cell-adhesion-molecule-1-is-a-marker-for-high-risk-carotid-plaques-and-target-for-ultrasound-molecular-imaging
#1
Craig C Weinkauf, Kirsten Concha-Moore, Jonathan R Lindner, Edmund R Marinelli, Kyle P Hadinger, Sandipan Bhattacharjee, Scott S Berman, Kay Goshima, Luis R Leon, Terry O Matsunaga, Evan Unger
BACKGROUND: Molecular imaging of carotid plaque vulnerability to atheroembolic events is likely to lead to improvements in selection of patients for carotid endarterectomy (CEA). The aims of this study were to assess the relative value of endothelial inflammatory markers for this application and to develop molecular ultrasound contrast agents for their imaging. METHODS: Human CEA specimens were obtained prospectively from asymptomatic (30) and symptomatic (30) patients...
February 13, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29435269/current-understanding-of-chronic-total-occlusion-of-the-internal-carotid-artery
#2
Baofeng Xu, Chao Li, Yunbao Guo, Kan Xu, Yi Yang, Jinlu Yu
At present, there is limited understanding of chronic total occlusion (CTO) of the internal carotid artery (ICA). Therefore, the present report collected related cases from PubMed and reviewed the literature. Cerebral vessels may form collateral circulation immediately or gradually following CTO of the ICA. The natural history of CTO of the ICA includes a variety of outcomes, all of which are biased toward a non-benign progressive process and are characterized by insufficient cerebral perfusion, embolus detachment and cognitive dysfunction...
February 2018: Biomedical Reports
https://www.readbyqxmd.com/read/29426593/an-updated-systematic-review-and-meta-analysis-of-outcomes-following-eversion-vs-conventional-carotid-endarterectomy-in-randomised-controlled-trials-and-observational-studies
#3
REVIEW
Kosmas I Paraskevas, Vaux Robertson, Athanasios N Saratzis, A Ross Naylor
INTRODUCTION: A 2011 meta-analysis comparing eversion (eCEA) with conventional (cCEA) carotid endarterectomy in 16,251 patients concluded that eCEA was associated with lower rates of peri-operative stroke and late occlusion compared with cCEA. However, randomised controlled trials (RCTs) showed no difference in outcomes. Since then, the literature contains outcome data on 49,500 patients undergoing eCEA or cCEA. An updated meta-analysis was performed to establish whether eCEA confers significant benefit over cCEA...
February 6, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29422277/revascularization-of-radiation-induced-carotid-artery-stenosis-with-carotid-endarterectomy-vs-carotid-artery-stenting-a-systematic-review-and-meta-analysis
#4
REVIEW
Stefanos Giannopoulos, Pavlos Texakalidis, Anil Kumar Jonnalagadda, Theofilos Karasavvidis, Spyridon Giannopoulos, Damianos G Kokkinidis
OBJECTIVE: The incidence of carotid artery stenosis after head and neck radiation is anticipated to rise due to the increasing survival of patients with head and neck malignancies. It remains unclear whether carotid artery stenting (CAS) or endarterectomy (CEA) is the best treatment strategy for radiation-induced carotid artery stenosis. MATERIALS & METHODS: This study was performed according to the PRISMA and MOOSE guidelines. Eligible studies were identified through a comprehensive search of PubMed, Scopus and Cochrane Central until July 20, 2017...
January 31, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29417939/apolipoprotein-j-as-a-predictive-biomarker-for-restenosis-after-carotid-endarterectomy-a-retrospective-study
#5
Anastasios Maskanakis, Nikolaos Patelis, Georgios Karaolanis, Spyridon Davakis, Dimitrios Schizas, Despina Perrea, Chris Klonaris, Sotirios Georgopoulos, Theodoros Liakakos, Chris Bakoyiannis
Carotid endarterectomy (CEA) is an effective surgical option for stroke prophylaxis in most patients. Restenosis after CEA can lead to re-intervention and adverse events, but the factors predicting restenosis are poorly understood. Apolipoprotein J (ApoJ) is considered to be a novel predictive factor of vascular restenosis and is associated with a large number of processes related to atherosclerosis and cell-cycle phases. The aim of this study was to elucidate the predictive value of Apo J in internal carotid artery (ICA) restenosis following CEA...
February 8, 2018: Acta Pharmacologica Sinica
https://www.readbyqxmd.com/read/29416470/bilateral-bispectral-index-monitoring-to-detect-cerebral-hypoperfusion-during-carotid-endarterectomy-under-general-anesthesia
#6
Jin Xi Zheng
The bilateral use of bispectral index (BIS) monitoring in a 68-year-old male who underwent right carotid endarterectomy (CEA) under general anesthesia (GA) is described. During three episodes of right internal carotid artery cross-clamping intraoperatively, the right BIS value rose relative to the left within 1 min of clamping, followed by a return to baseline within 1-2 min of clamp release. Since unilateral BIS values can decrease or increase in response to cross-clamping, a significant difference in left and right BIS values may provide a simple and easily available method to detect cerebral hypoperfusion during CEA under GA...
January 2018: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/29402628/total-intravenous-versus-volatile-induction-and-maintenance-of-anesthesia-in-elective-carotid-endarterectomy-effects-on-cerebral-oxygenation-and-cognitive-functions
#7
Vsevolod V Kuzkov, Maxim Y Obraztsov, Oleg Y Ivashchenko, Nadezhda Y Ivashchenko, Valery M Gorenkov, Mikhail Y Kirov
OBJECTIVE: Carotid endarterectomy (CEA) is effective for the prevention of stroke, yet can be associated with a postoperative cognitive dysfunction (POCD) that may be affected by the type of anesthesia. The aim of the study was to compare the effects of total intravenous anesthesia (TIVA) with propofol to volatile induction and maintenance of anesthesia (VIMA) with sevoflurane on cerebral tissue oxygen saturation (SctO2) and POCD. DESIGN: Single-center, pilot randomized prospective study...
January 5, 2018: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29397311/cerebral-neuromonitoring-during-carotid-endarterectomy-and-impact-of-contralateral-internal-carotid-occlusion
#8
Davorin Sef, Andrija Skopljanac-Macina, Milan Milosevic, Anita Skrtic, Vinko Vidjak
BACKGROUND: The aim of this study was to identify the reliability of carotid artery stump pressure (SP) in predicting the neurologic changes and correlation with contralateral internal carotid artery (ICA) occlusion in patients undergoing eversion carotid endarterectomy (CEA). The optimal method for monitoring cerebral perfusion during CEA, performed under either local or general anesthesia, is still controversial. METHODS: We prospectively analyzed 118 consecutive patients undergoing eversion CEA under local anesthesia...
January 31, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29395420/patient-characteristics-and-in-hospital-outcomes-of-emergency-carotid-endarterectomy-and-carotid-stenting-after-stroke-in-evolution
#9
Christoph Knappich, Andreas Kuehnl, Pavlos Tsantilas, Sofie Schmid, Thorben Breitkreuz, Michael Kallmayer, Alexander Zimmermann, Hans-Henning Eckstein
OBJECTIVE: The objective of this study was to describe characteristics and in-hospital outcomes of patients treated with carotid endarterectomy (CEA) and carotid artery stenting (CAS) for stroke in evolution (SIE) under routine conditions in Germany. METHODS: This secondary data analysis is based on the German statutory quality assurance database for carotid revascularization procedures. Patients with SIE who had undergone CEA or CAS were included. The primary outcome was any new stroke or all-cause death until hospital discharge...
January 27, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29393758/risk-of-intracranial-hemorrhage-after-carotid-artery-stenting-versus-endarterectomy-a-population-based-study
#10
Mohamad A Hussain, Aziz S Alali, Muhammad Mamdani, Jack V Tu, Gustavo Saposnik, Konard Salata, Avery B Nathens, Charles de Mestral, Deepak L Bhatt, Subodh Verma, Mohammed Al-Omran
OBJECTIVE Intracranial hemorrhage (ICH) associated with cerebral hyperperfusion syndrome is a rare but major complication of carotid artery revascularization. The objective of this study was to compare the rate of ICH after carotid artery stenting (CAS) with that after endarterectomy (CEA). METHODS The authors performed a retrospective population-based cohort study of patients who underwent carotid artery revascularization in the province of Ontario, Canada, between 2002 and 2015. The primary outcome was the rate of ICH that occurred within 90 days after carotid artery intervention among patients who underwent CAS versus that of those who underwent CEA...
February 2, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29376954/-an-efficacy-of-carotid-arteries-repair-for-tortuosity-combined-with-stenosis
#11
A V Gavrilenko, A V Abramyan, A V Kuklin
AIM: To assess an efficacy of carotid arteries reconstruction in patients with internal carotid artery stenosis combined with tortuosity. MATERIAL AND METHODS: 86 patients with ICA tortuosity and stenosis were enrolled. All patients were divided into groups depending on type of surgery: group I - open carotid endarterectomy (CEA) followed by obligatory repair with synthetic patch (31 (36%) patients); group II - eversion CEA with ICA resection, redressation and reimplantation into own ostium (35 (40...
2018: Khirurgiia
https://www.readbyqxmd.com/read/29362284/-endarterectomy-for-internal-carotid-artery-occlusion-with-an-aberrant-branch-of-the-internal-carotid-artery-maintaining-blood-flow-distal-to-the-complete-occlusion-a-case-report
#12
Shigeomi Yokoya, Hideki Oka, Asami Kikuchi, Youichi Hashimoto, Akihiko Hino
Doppler sonography accurately identifies occlusion of the internal carotid artery(ICA)and current surgical guidelines do not list an occluded ICA as an indication for carotid endarterectomy(CEA). We encountered an unusual case, for which we performed CEA. The left ICA was occluded by atherosclerosis, and was reconstituted via an aberrant branch of the occipital artery. A 71-year-old man was referred following brain infarction. Carotid duplex sonography(CDS)demonstrated occlusion of his left ICA, with flow in the distal ICA beyond the occlusion("Sandwich stump sign")...
January 2018: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/29361324/association-between-medicare-high-risk-criteria-and-outcomes-after-carotid-revascularization-procedures
#13
Caitlin W Hicks, Besma Nejim, Satinderjit Locham, Hanaa D Aridi, Marc L Schermerhorn, Mahmoud B Malas
BACKGROUND: The U.S. Centers for Medicare and Medicaid Services (CMS) has defined a set of high-risk criteria to help define patients who are appropriate for carotid artery stenting (CAS), but these criteria have never been validated. We aimed to validate the CMS high-risk criteria in a nationally representative cohort of patients undergoing CAS and carotid endarterectomy (CEA). METHODS: All patients undergoing CAS (with embolic protection) or CEA in the Vascular Quality Initiative (VQI) database (2013-2016) were included...
January 17, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29334161/the-role-of-neurosonology-in-the-diagnosis-and-management-of-patients-with-carotid-artery-disease-a-review
#14
REVIEW
Odysseas Kargiotis, Apostolos Safouris, Georgios Magoufis, Maria Georgala, Andromachi Roussopoulou, Eleftherios Stamboulis, Konstantinos G Moulakakis, Andreas Lazaris, George Geroulakos, Spyros Vasdekis, Georgios Tsivgoulis
Carotid artery disease (CAD) is a common cause of ischemic stroke with high rates of recurrence. Carotid endarterectomy (CEA) or carotid artery stenting (CAS) are highly recommended for the secondary prevention of symptomatic CAD during the first 14 days following the index event of transient ischemic attack or minor stroke. CEA or CAS may also be offered in selected cases with severe asymptomatic stenosis. Herein, we review the utility of neurosonology in the diagnosis and pre-/peri-interventional assessment of CAD patients who undergo carotid revascularization procedures...
January 15, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29322961/perioperative-strokes-following-combined-coronary-artery-bypass-grafting-and-carotid-endarterectomy-a-nationwide-perspective
#15
REVIEW
Reshmi Udesh, Hannah Cheng, Amol Mehta, Parthasarathy D Thirumala
BACKGROUND: To assess the risk of perioperative stroke on in-hospital morbidity and mortality following combined coronary artery bypass grafting (CABG) and carotid endarterectomy (CEA). MATERIALS AND METHODS: Data from the National Inpatient Sample (NIS) database for all patients who underwent CABG with CEA were identified using ICD-9 codes. Combined procedures were identified as CEA and CABG procedures that happened on the same day. Various preoperative and perioperative risk factors and their association with in-hospital mortality and morbidity were studied...
January 2018: Neurology India
https://www.readbyqxmd.com/read/29322480/intra-operative-video-characterization-of-carotid-artery-pulsation-patterns-in-case-series-with-post-endarterectomy-hypertension-and-hyperperfusion-syndrome
#16
Yiming Xiao, Hassan Rivaz, Hidetoshi Kasuya, Suguru Yokosako, Cristina Mindru, Jeanne Teitelbaum, Denis Sirhan, David Sinclair, Mark Angle, Benjamin W Y Lo
Cerebral hyperperfusion syndrome (CHS) is a complication that can occur after carotid endarterectomy (CEA), the treatment of choice to decrease the subsequent risk of fatal or disabling stroke for patients with symptomatic severe stenosis of the carotid artery. Because of its rarity and complexity, the mechanism of the condition is still unclear, making its prevention via prediction and monitoring challenging. This is especially true during surgery, when multiple factors can induce physiological changes, including blood pressure and baroreceptor functions, which are crucial factors for post-CEA hypertension and CHS...
January 10, 2018: Translational Stroke Research
https://www.readbyqxmd.com/read/29315509/carotid-plaque-volume-in-patients-undergoing-carotid-endarterectomy
#17
S Ball, S Rogers, K Kanesalingam, R Taylor, E Katsogridakis, C McCollum
BACKGROUND: The main indication for carotid endarterectomy (CEA) is severity of carotid artery stenosis, even though most strokes in carotid disease are embolic. The relationship between carotid plaque volume (CPV) and symptoms of cerebral ischaemia, and the measurement of CPV by minimally invasive tomographic ultrasound imaging, were investigated. METHODS: The volume of the endarterectomy specimen was measured using a validated saline suspension technique in patients undergoing CEA...
January 8, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29314704/use-of-a-novel-embolic-filter-in-carotid-artery-stenting-30-day-results-from-the-embolden-clinical-study
#18
William A Gray, Manish Mehta, Firas Alani, Karthikeshwar Kasirajan, Richard J Begg, J Michael Bacharach, Peter A Soukas
OBJECTIVES: The EMBOLDEN study was conducted to test the safety and efficacy of a novel emboli protection filter design for use in carotid artery stenting (CAS) in patients with severe carotid stenosis who were at high risk of operative complications from carotid endarterectomy (CEA). BACKGROUND: General considerations for filter design usually involve trade-offs between trackability/profile and wall apposition/capture efficiency. The GORE® Embolic Filter (GEF) is intended to address these design goals via a hybrid construction...
January 3, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29314596/multiplate%C3%A2-evaluation-of-acetylsalicylic-acid-efficacy-in-carotid-surgery-routine-and-genetic-influencing-factors
#19
S Roullet, S Labrouche, C Carrie, H Auque, X Berard, G Freyburger
BACKGROUND: Acetylsalicylic acid (ASA) is recommended before, during and after carotid endarterectomy (CEA). Efficacy of ASA is influenced by numerous biological and genotypic factors. OBJECTIVES: To determine the biological efficacy of ASA by using the Multiplate® method and to explore the biological parameters and genomic factors influencing this efficacy. METHODS: This descriptive cross-sectional study included all patients scheduled for CEA between January 2012 and April 2013...
January 3, 2018: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29305914/the-comparison-of-monitoring-of-cerebral-blood-flow-by-c-flow-and-transcranial-doppler-in-carotid-endarterectomy
#20
Xu Wang, Bin Yang, Yan Ma, Peng Gao, Yabing Wang, Yanfei Chen, Liqun Jiao, Feng Ling, Guoguang Zhao
OBJECTIVE: To prospectively compare the use of the c-FLOW (cerebral blood flow monitor) and transcranial Doppler (TCD) as two techniques for assessing brain perfusion during carotid endarterectomy (CEA). METHODS: This was a prospective, single center, observational study. All patients were monitored using c-FLOW and TCD during the operation. Changes from baseline values of cerebral blood flow index (CFI) and blood flow velocity of middle cerebral artery (V-MCA) were recorded following carotid artery clamping and unclamping...
January 3, 2018: World Neurosurgery
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