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Sexual differentiation

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https://www.readbyqxmd.com/read/28738663/statistical-approach-for-atr-ftir-screening-of-semen-in-sexual-evidence
#1
Inês Gregório, Félix Zapata, Mercedes Torre, Carmen García-Ruiz
Genetic identification has revolutionized the Forensic Sciences, especially in sexual aggression cases. For the successful extraction of the genetic information of a criminal, a crucial step is the prior detection of bodily fluids on evidence. In this article, a method for non-destructive screening of semen samples is reported. Using chemometric tools, bodily fluids can be detected and differentiated without damaging the sample, by correlating the infrared spectra of sexual evidence with previously recorded spectra from undamaged stains of individual bodily fluids...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28736678/rapid-assessment-zika-virus-knowledge-among-clinical-specialists-in-singapore-a-cross-sectional-survey
#2
Chee F Yung, Clarence C Tam, Victor S Rajadurai, Jerry Ky Chan, Mabel Sf Low, Yong H Ng, Koh C Thoon, Lay K Tan
INTRODUCTION: We report the results of a rapid assessment of Zika virus awareness among key clinical specialties in Singapore. METHODS: Between June 6 and June 19, 2016 we conducted an online survey of doctors working in obstetrics and gynaecology, neonatology and paediatrics in Singapore. The survey included 15 multiple choice questions to measure respondents' knowledge of Zika virus in four domains covering clinical and public health. RESULTS: A total of 110 survey responses (15% response rate) were obtained, 82% of respondents worked in the public sector...
May 3, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28734801/sex-specific-differences-in-the-modulation-of-growth-differentiation-factor-15-gdf15-by-hyperoxia-in-vivo-and-in-vitro-role-of-hif-1%C3%AE
#3
Yuhao Zhang, Weiwu Jiang, Lihua Wang, Krithika Lingappan
Male premature neonates are more susceptible than females to the development of bronchopulmonary dysplasia (BPD). The reasons underlying sexually dimorphic outcomes in premature neonates are not known. GDF15 (Growth and differentiation factor 15) is a secreted cytokine and plays a role in cell proliferation, apoptosis, and angiogenesis. In this study, we sought to elucidate the sex-specific expression of Gdf15 in the lung in vivo in neonatal hyperoxic lung injury and its regulation by Hif-1α, and to delineate the differences in GDF15 expression in male and female human umbilical venous endothelial cells in an in vitro model of oxygen toxicity...
July 19, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28733418/a-simple-method-to-induce-meiosis-and-sporulation-semisynchronously-in-the-fission-yeast-schizosaccharomyces-pombe
#4
Akira Yamashita, Takeshi Sakuno, Yoshinori Watanabe, Masayuki Yamamoto
Schizosaccharomyces pombe cells initiate a sexual differentiation program, which comprises meiosis and spore formation, on nitrogen starvation. This protocol describes a simple procedure to induce meiosis and sporulation semisynchronously in heterozygous diploid S. pombe cells. The procedure is appropriate for a variety of applications, including fluorescence-activated cell sorting (FACS) and northern and western blotting. Zygotic meiosis can also be induced by the same procedure, although less synchronously...
July 21, 2017: Cold Spring Harbor Protocols
https://www.readbyqxmd.com/read/28733413/live-cell-imaging-of-the-schizosaccharomyces-pombe-sexual-life-cycle
#5
Laura Merlini, Aleksandar Vjestica, Omaya Dudin, Felipe Bendezú, Sophie G Martin
The fission yeast Schizosaccharomyces pombe is an invaluable model system for studying the principles that drive sexual differentiation and the meiotic cell division cycle. We describe a simple protocol for microscopic observation of the entire sexual life cycle that can be adapted to focus on specific stages of sexual differentiation. After growth to exponential phase in a nitrogen-rich medium, cell cultures are switched to a nitrogen-deprived medium until the population is enriched for the specific stage of the sexual lifecycle to be studied...
July 21, 2017: Cold Spring Harbor Protocols
https://www.readbyqxmd.com/read/28731499/the-frontal-sinus-cavity-exhibits-sexual-dimorphism-in-3d-cone-beam-ct-images-and-can-be-used-for-sex-determination
#6
Isabela G G Choi, Eduardo F Duailibi-Neto, Thiago L Beaini, Renan L B da Silva, Israel Chilvarquer
Few studies have assessed the use of the frontal sinus cavities for sex differentiation. In this study, a new methodology was used to assess the reliability of CBCT images of the frontal sinus cavity for determining sex based on the sexual dimorphism found in this anatomical structure. The survey sample consisted of 130 scans that were reconstructed three-dimensionally. 3D images of the cavity volume in the frontal, lateral, and basal views were exported in TIFF. The following variables were measured in a second program: area, perimeter, bounding rectangle, ellipse fit, circularity, aspect ratio, roundness, solidity, and Feret's diameter...
July 21, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28728619/restless-genital-syndrome-differential-diagnosis-and-treatment-with-pramipexole
#7
Emilia Sforza, David Hupin, Frédéric Roche
Restless genital syndrome refers to excessive and persistent sensations of genital and clitoral arousal with the absence of conscious feeling of sexual desire. These sensations have been linked to symptoms of restless legs syndrome (RLS) or an overactive bladder. Restless genital syndrome may be related to small fiber sensory neuropathy of the dorsal nerve of the clitoris, so it more frequently occurs in women. The association with RLS suggests a possible dopaminergic mechanism. We report a case of a 74-year-old woman who presented restless genital symptoms every night in association with RLS symptoms...
July 14, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28725401/sky-island-bird-populations-isolated-by-ancient-genetic-barriers-are-characterized-by-different-song-traits-than-those-isolated-by-recent-deforestation
#8
Chetana B Purushotham, V V Robin
Various mechanisms of isolation can structure populations and result in cultural and genetic differentiation. Similar to genetic markers, for songbirds, culturally transmitted sexual signals such as breeding song can be used as a measure of differentiation as songs can also be impacted by geographic isolation resulting in population-level differences in song structure. Several studies have found differences in song structure either across ancient geographic barriers or across contemporary habitat barriers owing to deforestation...
October 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/28717389/sexual-selection-reinforces-a-higher-flight-endurance-in-urban-damselflies
#9
Nedim Tüzün, Lin Op de Beeck, Robby Stoks
Urbanization is among the most important and globally rapidly increasing anthropogenic processes and is known to drive rapid evolution. Habitats in urbanized areas typically consist of small, fragmented and isolated patches, which are expected to select for a better locomotor performance, along with its underlying morphological traits. This, in turn, is expected to cause differentiation in selection regimes, as populations with different frequency distributions for a given trait will span different parts of the species' fitness function...
August 2017: Evolutionary Applications
https://www.readbyqxmd.com/read/28710131/gene-regulatory-networks-for-the-haploid-to-diploid-transition-of-chlamydomonas-reinhardtii
#10
Sunjoo Joo, Yoshiki Nishimura, Evan Cronmiller, Ran Ha Hong, Thamali Kariyawasam, Ming Hsiu Wang, Nai Chun Shao, Saif-El-Din El Akkad, Takamasa Suzuki, Tetsuya Higashiyama, EonSeon Jin, Jae-Hyeok Lee
The sexual cycle of the unicellular Chlamydomonas reinhardtii culminates in the formation of diploid zygotes which differentiate into dormant spores that eventually undergo meiosis. Mating between gametes induces rapid cell wall shedding via the enzyme g-lysin; cell fusion is followed by heterodimerization of sex-specific homeobox transcription factors, GSM1 and GSP1, and initiation of zygote-specific gene expression. To investigate the genetic underpinnings of the zygote developmental pathway, we performed comparative transcriptome analysis of both pre- and post-fertilization samples...
July 14, 2017: Plant Physiology
https://www.readbyqxmd.com/read/28705398/very-long-chain-aldehydes-induce-appressorium-formation-in-ascospores-of-the-wheat-powdery-mildew-fungus-blumeria-graminis
#11
Mo Zhu, Markus Riederer, Ulrich Hildebrandt
Asexually produced conidia of the wheat powdery mildew fungus Blumeria graminis f. sp. tritici (Bgt) are known to perceive cuticular very-long-chain aldehydes as signal substances strongly stimulating germination and differentiation of infection structures in a concentration- and chain-length-dependent manner. Conidial germination and appressorium formation are widely prevented by the presence of free water on the host surface. However, sexually produced ascospores can differentiate immersed in water. Applying a Formvar(®)-based in vitro-system showed that ascospore appressorium formation was strongly induced by the presence of wheat leaf cuticular wax...
August 2017: Fungal Biology
https://www.readbyqxmd.com/read/28701734/long-noncoding-rna-expression-profile-changes-associated-with-dietary-energy-in-the-sheep-testis-during-sexual-maturation
#12
Yanli Zhang, Hua Yang, Le Han, Fengzhe Li, Tingting Zhang, Jing Pang, Xu Feng, Caifang Ren, Shengyong Mao, Feng Wang
Spermatogenesis can be affected by nutrition, which operates through normal physiological processes by changing the testicular mass and hormone levels profoundly. However, little is known regarding how testis development is regulated by long noncoding RNA (lncRNA). In this study, we investigated the effects of high-grain (HG) feeding on testis development during sexual maturation mediated by lncRNA. The HG diet group showed an increase in growth hormone (GH), insulin-like growth factor-1 (IGF-1) and testosterone (T) levels, and in the number of sperm in the seminiferous tubules compared with the hay-fed group (p  < 0...
July 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28694801/the-gata-type-transcription-factor-csm1-regulates-conidiation-and-secondary-metabolism-in-fusarium-fujikuroi
#13
Eva-Maria Niehaus, Julia Schumacher, Immo Burkhardt, Patrick Rabe, Eduard Spitzer, Martin Münsterkötter, Ulrich Güldener, Christian M K Sieber, Jeroen S Dickschat, Bettina Tudzynski
GATA-type transcription factors (TFs) such as the nitrogen regulators AreA and AreB, or the light-responsive TFs WC-1 and WC-2, play global roles in fungal growth and development. The conserved GATA TF NsdD is known as an activator of sexual development and key repressor of conidiation in Aspergillus nidulans, and as light-regulated repressor of macroconidia formation in Botrytis cinerea. In the present study, we functionally characterized the NsdD ortholog in Fusarium fujikuroi, named Csm1. Deletion of this gene resulted in elevated microconidia formation in the wild-type (WT) and restoration of conidiation in the non-sporulating velvet mutant Δvel1 demonstrating that Csm1 also plays a role as repressor of conidiation in F...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28688453/mycoplasma-pneumoniae-as-a-cause-of-vulvar-ulcers-in-a-non-sexually-active-girl-a-case-report
#14
Maria G Koliou, Talia Kakourou, Jan Richter, Christina Christodoulou, Elpidoforos S Soteriades
BACKGROUND: Non-sexually active young females very rarely develop genital ulcers. Such ulcers pose a diagnostic challenge as well as physical and emotional distress for patients and family; therefore, the search for their etiology requires exhaustive investigation. Several viruses such as Epstein-Barr virus have been associated with this entity; however, Mycoplasma pneumoniae has rarely been linked to such ulcers in the literature. We present a case of vulvar ulcers in a non-sexually active young girl during the course of pneumonia caused by Mycoplasma pneumoniae...
July 9, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28683981/noradrenergic-modulation-of-neural-erotic-stimulus-perception
#15
Heiko Graf, Maike Wiegers, Coraline Danielle Metzger, Martin Walter, Georg Grön, Birgit Abler
We recently investigated neuromodulatory effects of the noradrenergic agent reboxetine and the dopamine receptor affine amisulpride in healthy subjects on dynamic erotic stimulus processing. Whereas amisulpride left sexual functions and neural activations unimpaired, we observed detrimental activations under reboxetine within the caudate nucleus corresponding to motivational components of sexual behavior. However, broadly impaired subjective sexual functioning under reboxetine suggested effects on further neural components...
July 3, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28683952/identification-and-profile-of-micrornas-in-xiang-pig-testes-in-four-different-ages-detected-by-solexa-sequencing
#16
Zhi-Yu Luo, Xin-Lan Dai, Xue-Qin Ran, Yong-Xiu Cen, Xi Niu, Shi-Hui Huang, Jia-Fu Wang
To further understand the role of microRNA (miRNA) during testicular development, we constructed four small RNA libraries from the testes of the Chinese indigenous Xiang pig at four different ages, which were sequenced using high-throughput Solexa deep sequencing methods. It yielded over 23 million high-quality reads and 1,342,579 unique sequences. At two and three months of age, the proportion which represented miRNAs was the most abundant class of small RNAs, but it was gradually replaced by the category that represented piRNAs in adult testes...
June 28, 2017: Theriogenology
https://www.readbyqxmd.com/read/28683784/decreasing-seroprevalence-of-herpes-simplex-virus-type-1-and-type-2-in-germany-leaves-many-people-susceptible-to-genital-infection-time-to-raise-awareness-and-enhance-control
#17
Gerit Korr, Michael Thamm, Irina Czogiel, Christina Poethko-Mueller, Viviane Bremer, Klaus Jansen
BACKGROUND: Herpes simplex infections (HSV1/2) are characterized by recurrent symptoms, a risk of neonatal herpes, and the facilitation of HIV transmission. In Germany, HSV1/2 infections are not notifiable and data are scarce. A previous study found higher HSV1/2 seroprevalences in women in East Germany than in women in West Germany. We assessed changes in the HSV1/2 seroprevalences over time and investigated determinants associated with HSV1/2 seropositivity to guide prevention and control...
July 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28682107/eating-disorder-symptoms-in-female-veterans-the-role-of-childhood-adult-and-military-trauma-exposure
#18
Kimberly A Arditte Hall, Brooke A Bartlett, Katherine M Iverson, Karen S Mitchell
OBJECTIVE: Eating disorders are understudied among female U.S. military veterans, who may be at increased risk due to their high rates of trauma exposure and trauma-related sequelae. The current study sought to examine whether different types of trauma in childhood and adulthood confer differential risk for eating disorder symptoms (EDSs) in this population. METHOD: We analyzed survey data from a sample of female Veterans Health Administration patients (N = 186) to examine the association between 5 trauma types (i...
July 6, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/28679591/greater-transforming-growth-factor-%C3%AE-in-adult-female-shr-is-dependent-on-blood-pressure-but-does-not-account-for-sex-differences-in-renal-t-regulatory-cells
#19
Ashlee J Tipton, Jacqueline B Musall, G Ryan Crislip, Jennifer C Sullivan
Female spontaneously hypertensive rats (SHR) have more renal regulatory T cells (Tregs) than males, and greater levels of Tregs in female SHR is dependent on blood pressure (BP). However, the molecular mechanism responsible for greater Tregs in female SHR is unknown. Transforming growth factor (TGF)-β is a pleiotropic cytokine critical in the differentiation of naïve T cells into Tregs, and female SHR have higher TGF-β excretion than male SHR. The goals of the current study were to test the hypotheses that 1) female SHR have greater renal TGF-β expression than male SHR which is dependent on BP and 2) neutralizing TGF-β will decrease renal Tregs in female SHR...
July 5, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28678822/father-absence-and-gendered-traits-in-sons-and-daughters
#20
Lynda G Boothroyd, Catharine P Cross
Research has previously found a number of apparently contradictory patterns in the relationship between 'father absence' (having a non-resident father during childhood) and the expression of gender roles, as well as other sexually dimorphic traits such as aggression. In the current study we measured a battery of sexually differentiated traits in relation to family background. 133 men and 558 women from the United States and Australia completed the Bem Sex Role Inventory, the Barrett Impulsivity Scale, the Fear Survey Schedule and the Buss & Perry Aggression Questionnaire...
2017: PloS One
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