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https://www.readbyqxmd.com/read/28209953/-extracorporeal-partial-nephrectomy-under-pharmaco-cold-ischemia-for-renal-cell-carcinoma
#1
A A Gritskevich, I V Miroshkina, S S Piyanikin, Z A Adyrkhayev, Yu A Stepanova, A E Zotikov, A A Teplov, V A Kubyshkin, A Sh Revishvili
AIM: To develop the method for extracorporeal partial nephrectomy under pharmaco-cold ischemia without ureter intersection with orthotopic replantation of renal vessels for RCC. MATERIAL AND METHODS: The study included 37 patients with morphologically confirmed RCC pT1a-Т3bN0M0-1G1-3 with intraparenchymal and central location of the tumor in cases of single kidney, comorbidity of contralateral kidney and kidney on the side of lesion. RESULTS: Mean surgery time was 413...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28188362/comparing-renal-function-preservation-after-laparoscopic-radio-frequency-ablation-assisted-tumor-enucleation-and-laparoscopic-partial-nephrectomy-for-clinical-t1a-renal-tumor-using-a-3d-parenchyma-measurement-system
#2
Liangsong Zhu, Guangyu Wu, Jiwei Huang, Jianfeng Wang, Ruiyun Zhang, Wen Kong, Wei Xue, Yiran Huang, Yonghui Chen, Jin Zhang
PURPOSE: To compare the renal function preservation between laparoscopic radio frequency ablation assisted tumor enucleation and laparoscopic partial nephrectomy. METHODS: Data were analyzed from 246 patients who underwent laparoscopic radio frequency ablation assisted tumor enucleation and laparoscopic partial nephrectomy for solitary cT1a renal cell carcinoma from January 2013 to July 2015. To reduce the intergroup difference, we used a 1:1 propensity matching analysis...
February 10, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28108975/3d-printed-soft-tissue-physical-models-of-renal-malignancies-for-individualized-surgical-simulation-a-feasibility-study
#3
Michael M Maddox, Allison Feibus, James Liu, Julie Wang, Raju Thomas, Jonathan L Silberstein
To construct patient-specific physical three-dimensional (3D) models of renal units with materials that approximates the properties of renal tissue to allow pre-operative and robotic training surgical simulation, 3D physical kidney models were created (3DSystems, Rock Hill, SC) using computerized tomography to segment structures of interest (parenchyma, vasculature, collection system, and tumor). Images were converted to a 3D surface mesh file for fabrication using a multi-jet 3D printer. A novel construction technique was employed to approximate normal renal tissue texture, printers selectively deposited photopolymer material forming the outer shell of the kidney, and subsequently, an agarose gel solution was injected into the inner cavity recreating the spongier renal parenchyma...
January 20, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/28057986/intraoperative-ultrasound-control-of-surgical-margins-during-partial-nephrectomy
#4
Feras M Alharbi, Charles K Chahwan, Sophie G Le Gal, Kerem M Guleryuz, Xavier P Tillou, Arnaud P Doerfler
AIMS: To evaluate a simple and fast technique to ensure negative surgical margins on partial nephrectomies, while correlating margin statuses with the final pathology report. SUBJECTS AND METHODS: This study was conducted for patients undergoing partial nephrectomy (PN) with T1-T2 renal tumors from January 2010 to the end of December 2015. Before tumor removal, intraoperative ultrasound (US) localization was performed. After tumor removal and before performing hemostasis of the kidney, the specimens were placed in a saline solution and a US was performed to evaluate if the tumor's capsule were intact, and then compared to the final pathology results...
October 2016: Urology Annals
https://www.readbyqxmd.com/read/28011276/excised-parenchymal-mass-during-partial-nephrectomy-functional-implications
#5
W Dong, Z Zhang, J Zhao, J Wu, C Suk-Ouichai, D Aguilar Palacios, E Carabello Antonio, S Babbar, E M Remer, J Li, S Isharwal, J Zabell, S C Campbell
OBJECTIVE: To evaluate whether excised parenchymal mass (EPM) during partial nephrectomy (PN) correlates with functional decline and can serve as a surrogate for functional outcomes. MATERIALS AND METHODS: All 215 patients managed with PN for unifocal renal mass with necessary studies to determine EPM and percent glomerular filtration rate (GFR) and parenchymal mass preserved (both global and specific to the operated kidney) were analyzed. EPM was estimated from the pathologic specimen by subtracting the tumor mass from specimen mass, with both calculated using the elliptical formula...
December 20, 2016: Urology
https://www.readbyqxmd.com/read/28009142/robotic-kidney-transplantation-current-status-and-future-perspectives
#6
Angelo Territo, Alex Mottrie, Ronney Abaza, Craig Rogers, Mani Menon, Mahendra Bhandari, Rajesh Ahlawat, Alberto Breda
INTRODUCTION: For the treatment of patients with end-stage renal disease, kidney transplantation is preferred to renal replacement modalities such as hemodialysis and peritoneal dialysis. Although open surgery remains the gold standard, minimally invasive approaches have recently been applied in transplant kidney surgery. Despite growing enthusiasm and potential benefits of robotic kidney transplant, many aspects of this novel technique remain controversial. Aim of this study was to analyze the current status and future developments in robotic-assisted surgery for kidney transplantation...
2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/27982263/glomerular-loss-after-arteriovenous-and-arterial-clamping-for-renal-warm-ischemia-in-a-swine-model
#7
Gustavo Ruschi Bechara, José Aurelino Damasceno-Ferreira, Leonardo Albuquerque Dos Santos Abreu, Waldemar Silva Costa, Francisco José Barcellos Sampaio, Marco Aurélio Pereira-Sampaio, Diogo Benchimol De Souza
PURPOSE: To evaluate the glomerular loss after arteriovenous or arterial warm ischemia in a swine model. METHODS: Twenty four pigs were divided into Group Sham (submitted to all surgical steps except the renal ischemia), Group AV (submitted to 30 minutes of warm ischemia by arteriovenous clamping of left kidney vessels), and Group A (submitted to 30 minutes of ischemia by arterial clamping). Right kidneys were used as controls. Weigh, volume, cortical volume, glomerular volumetric density (Vv[Glom]), volume-weighted glomerular volume (VWGV), and the total number of glomeruli were measured for each organ...
November 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27960537/has-sliding-clip-renorrhaphy-eliminated-the-need-for-collecting-system-repair-during-robot-assisted-partial-nephrectomy
#8
Robert D Williams, Caroline Snowden, Ryan Frank, David D Thiel
OBJECTIVE: We evaluated whether single-layer renorrhaphy (SLR) without collecting system (CS) closure is sufficient following robot-assisted partial nephrectomy (RAPN). PATIENTS AND METHODS: One hundred fifty consecutive patients underwent RAPN by a single surgeon and were prospectively labeled with regard to CS entry during surgery. Patients with CS entry were subdivided into two groups: those with classical renorrhaphy (CR) (i.e., two-layer repair) and those with SLR (i...
January 16, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/27936928/use-of-main-renal-artery-clamping-predominates-over-minimal-clamping-techniques-during-robotic-partial-nephrectomy-for-complex-tumors
#9
Leedor Lieberman, Ravi Barod, Deepansh Dalela, Mireya Diaz-Insua, Ronney Abaza, James Adshead, Rajesh Ahlawat, Benjamin Challacombe, Prokar Dasgupta, Giogio Gandaglia, Daniel A Moon, Giacomo Novara, Francesco Porpiglia, Alexandre Mottrie, Mahendra Bhandari, Craig Rogers
INTRODUCTION: Hilar clamping is often performed to facilitate robotic partial nephrectomy (RPN). Minimal clamping techniques may reduce renal ischemia, including early unclamping, selective clamping, and off-clamp RPN. We assess the utilization of clamping techniques in a large international consortium of surgeons performing RPN for complex tumors. METHODS: We retrospectively evaluated 721 patients with complex tumors, who underwent RPN at 11 centers worldwide between 2008 and 2014...
February 2017: Journal of Endourology
https://www.readbyqxmd.com/read/27928811/laparoscopic-versus-open-partial-nephrectomy-for-stage-t1a-of-renal-tumors
#10
Gholam Hossein Rezaeetalab, Hormoz Karami, Farid Dadkhah, Nasser Simforoosh, Nasser Shakhssalim
PURPOSE: Partial nephrectomy is the gold standard treatment for small kidney masses. Data on the comparison oflaparoscopic (LPN) versus open partial nephrectomy (OPN) are based on retrospective studies. Thus, we plannedto compare these two techniques in a prospective trial. MATERIALS AND METHODS: The study population consisted of patients over 18 years old with single renal mass of≤ 4 cm. Patients were divided into two groups considering their preference. Study arms were matched accordingto age, gender, tumor size and location and renal nephrometry score...
8, 2016: Urology Journal
https://www.readbyqxmd.com/read/27927035/robotic-partial-nephrectomy-for-posterior-tumors-through-a-retroperitoneal-approach-offers-decreased-length-of-stay-compared-with-the-transperitoneal-approach-a-propensity-matched-analysis
#11
Matthew J Maurice, Jihad H Kaouk, Daniel Ramirez, Sam B Bhayani, Mohamad E Allaf, Craig G Rogers, Michael D Stifelman
INTRODUCTION: We sought to compare surgical outcomes between transperitoneal and retroperitoneal robotic partial nephrectomy (RPN) for posterior tumors. PATIENTS AND METHODS: Using our multi-institutional RPN database, we reviewed 610 consecutive cases for posterior renal masses treated between 2007 and 2015. Primary outcomes were complications, operative time, length of stay (LOS), surgical margin status, and estimated glomerular filtration rate (eGFR) preservation...
February 2017: Journal of Endourology
https://www.readbyqxmd.com/read/27901336/robotic-kidney-transplantation-current-status-and-future-perspectives
#12
Angelo Territo, Alex Mottrie, Ronney Abaza, Craig Rogers, Mani Menon, Mahendra Bhandari, Rajesh Ahlawat, Alberto Breda
INTRODUCTION: For the treatment of patients with end-stage renal disease, kidney transplantation is preferred to renal replacement modalities such as hemodialysis and peritoneal dialysis. Although open surgery remains the gold standard, minimally invasive approaches have recently been applied in transplant kidney surgery. Despite growing enthusiasm and potential benefits of robotic kidney transplant, many aspects of this novel technique remain controversial. Aim of this study was to analyze the current status and future developments in robotic-assisted surgery for kidney transplantation...
November 30, 2016: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/27878419/split-renal-function-of-both-kidneys-after-robot-assisted-partial-nephrectomy-for-renal-tumor-larger-than-4%C3%A2-cm
#13
Sheng-Han Tsai, Yi-Chen Lai, Nai-Yuan Wu, Hsiao-Jen Chung
PURPOSE: Relative few studies reported the changes in split renal function using renal scintigraphy for robot-assisted partial nephrectomy (RaPN) for renal tumor >4 cm. This study aimed at demonstrating that RaPN is safe for renal tumor >4 cm without damaging the renal function of ipsilateral and contralateral kidney. METHODS: Patients who underwent RaPN for single renal tumor from December 2009 to December 2013 were identified from a prospectively collected database...
November 22, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27878046/back-to-back-comparison-of-mini-open-vs-laparoscopic-technique-for-living-kidney-donation
#14
Christie Rampersad, Premal Patel, Joshua Koulack, Thomas McGregor
INTRODUCTION: Laparoscopic living donor nephrectomy is the standard of care at high-volume renal transplant centres, with benefits over the open approach well-documented in the literature. Herein, we present a retrospective analysis of our single-institution donor nephrectomy series comparing the mini-open donor nephrectomy (mini-ODN) to the laparoscopic donor nephrectomy (LDN) with regards to operative, donor, and recipient outcomes. METHODS: From 2007-2011, there were 89 cases of mini-ODN, at which point our centre transitioned to LDN; 94 cases were performed from 2011-2014...
August 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27852391/-outcomes-of-mini-flank-incision-for-open-partial-nephrectomy-for-stage-t1b-renal-tumor
#15
H X Chen, X Y Hu, J M Guo, G M Wang, H Wang
Objective: To evaluate the safety and efficacy of mini-flank incision for open partial nephrectomy for stage T1b renal tumor. Methods: The data of patients with stage T1b renal tumor who underwent mini-flank incision for open partial nephrectomy between January 2010 to September 2015 were retrospectively reviewed. The Nephron-sparing surgery (NSS) was performed through mini-flank supra-12th rib incision under general anesthesia. Results: A total of 47 patients(31 male and 16 female) were enrolled in our study...
November 1, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27815183/associating-the-learning-curve-and-tumor-anatomical-complexity-with-the-margins-ischemia-and-complications-rate-after-robot-assisted-partial-nephrectomy
#16
Yongpeng Xie, Xin Ma, Liangyou Gu, Hongzhao Li, Xiangjun Lv, Yu Gao, Yuanxin Yao, Luyao Chen, Yu Zhang, Xu Zhang
OBJECTIVES: In this paper, we report the robot-assisted partial nephrectomy (RAPN) outcomes of our institution by using the margins, ischemia, and complications (MIC) system, which was recently proposed to standardize the evaluation of partial nephrectomy outcomes and observe the effect of learning curve and tumor anatomical complexity on the results. PATIENTS AND METHODS: We conducted a retrospective analysis of our prospectively maintained database of 144 patients treated with RAPN by one surgeon from May 2013 to May 2014...
December 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27806631/does-the-level-of-assistant-experience-impact-operative-outcomes-for-robot-assisted-partial-nephrectomy
#17
Emmanuel Mitsinikos, George A Abdelsayed, Zoe Bider, Patrick S Kilday, Peter A Elliott, Pooya Banapour, Gary W Chien
PURPOSE: A skilled assistant surgeon is presumed necessary during robot-assisted partial nephrectomy (RAPN) to minimize warm ischemia time (WIT) and to facilitate complex renorrhaphy. Studies observing impact of resident participation have focused on robotic prostatectomies, showing no impact on core surgical outcomes. Herein, we evaluated the level of experience of the bedside assistant and its impact on perioperative outcomes in RAPN. MATERIALS AND METHODS: All RAPN cases in our healthcare system from January 2011 to December 2013 were retrospectively reviewed...
January 2017: Journal of Endourology
https://www.readbyqxmd.com/read/27778492/laparoscopic-partial-nephrectomy-for-multiple-four-tumors
#18
Lessandro Curcio, Bruno Salama, Daniel Luis Pinto, Antonio Claudio Ahouagi
BACKGROUND: Nephron sparing surgery (NSS) is well established as the standard of care for most surgical small renal tumors when technically feasible. While the majority of sporadic renal tumors are solitary, multifocal tumors have been reported in 5.4% to 25% of patients with tumors smaller than 5cm. We present a video where we approach, through laparoscopy, four tumors on the same kidney. CASE STUDY: Male, 58y, went through a routine abdominal ultrasound which showed a 5cm left kidney nodule...
October 20, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27754425/ouabain-contributes-to-kidney-damage-in-a-rat-model-of-renal-ischemia-reperfusion-injury
#19
Luca Villa, Roberta Buono, Mara Ferrandi, Isabella Molinari, Fabio Benigni, Arianna Bettiga, Giorgia Colciago, Masami Ikehata, Elisabetta Messaggio, Maria Pia Rastaldi, Francesco Montorsi, Andrea Salonia, Paolo Manunta
Warm renal ischemia performed during partial nephrectomy has been found to be associated with kidney disease. Since endogenous ouabain (EO) is a neuro-endocrine hormone involved in renal damage, we evaluated the role of EO in renal ischemia-reperfusion injury (IRI). We measured plasma and renal EO variations and markers of glomerular and tubular damage (nephrin, KIM-1, Kidney-Injury-Molecule-1, α1 Na-K ATPase) and the protective effect of the ouabain inhibitor, rostafuroxin. We studied five groups of rats: (1) normal; (2) infused for eight weeks with ouabain (30 µg/kg/day, OHR) or (3) saline; (4) ouabain; or (5) saline-infused rats orally treated with 100 µg/kg/day rostafuroxin for four weeks...
October 14, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27752008/systemic-immunologic-and-inflammatory-response-after-transperitoneal-versus-retroperitoneal-laparoscopic-donor-nephrectomy-a-prospective-observational-study
#20
Debojit Gogoi, Dilip Kumar Pal, Malay K Bera
Laparoscopic donor nephrectomy (LDN) can be performed via either transperitoneal or retroperitoneal approach. Very few studies have been carried out till now, comparing immunologic and inflammatory responses in donors after these two approaches. This is a prospective observational study. Selection of approach was decided by the operating surgeon. All patients underwent peripheral venous blood sampling preoperatively and 24 h postoperatively for the measurement of C-reactive protein (CRP), interleukein-6 (IL-6), total leukocyte count (TLC), blood urea nitrogen (BUN), and serum creatinine (SCr)...
September 2016: Saudi Journal of Kidney Diseases and Transplantation
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