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https://www.readbyqxmd.com/read/29774822/partial-nephrectomy-in-central-renal-tumors
#1
Sohrab Arora, Craig Rogers
Nephron-sparing surgery, especially through a minimally invasive approach, is increasingly being performed for incidentally detected renal masses with excellent outcomes. Tumors in central location remain a surgical challenge during nephron-sparing surgery. In this chapter, we discuss the minimally invasive management of these tumors, which include complex hilar tumors and endophytic central tumors, with a focus on surgical technique. The key to management of these tumors is to maintain good preoperative hydration, achieving adequate exposure of tumor, and the use of intraoperative ultrasound to plan the resection plane...
May 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29761690/assessment-of-the-relationship-between-renal-volume-and-renal-function-after-minimally-invasive-partial-nephrectomy-the-role-of-computed-tomography-and-nuclear-renal-scan
#2
Riccardo Bertolo, Cristian Fiori, Federico Piramide, Daniele Amparore, Monica Barrera, Diego Sardo, Andrea Veltri, Francesco Porpiglia
BACKGROUND: To evaluate the correlation between the loss of renal function as assessed by Tc99MAG-3 renal scan and the loss of renal volume as calculated by volumetric assessment on CT-scan in patients who underwent minimally-invasive partial nephrectomy (PN). METHODS: PN prospectively-maintained database was retrospectively queried for patients who underwent minimally-invasive PN (2012-2017) for renal mass <cT2 and had complete data on renal scan and contrast-enhanced CT-scan (both performed in our Institution) both at preoperative assessment and at the third postoperative month follow-up...
May 14, 2018: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29759510/predicting-morbidity-after-robotic-partial-nephrectomy-the-effect-of-tumor-environment-and-patient-related-factors
#3
Zine-Eddine Khene, Benoit Peyronnet, Neil J Kocher, Haley Robyak, Corentin Robert, Benjamin Pradere, Emmanuel Oger, Solène-Florence Kammerer-Jacquet, Grégory Verhoest, Nathalie Rioux-Leclercq, Romain Mathieu, Jay D Raman, Karim Bensalah
PURPOSE: To investigate the effect of tumor and nontumor related parameters on perioperative outcomes of robotic partial nephrectomy (RPN). PATIENTS AND METHODS: Patients who underwent RPN for a localized renal tumor at 2 institutions between June 2010 and November 2016 were reviewed. RENAL and Mayo adhesive probability (MAP) scores were calculated and information on comorbid conditions including ASA score, performance status, Charlson's comorbidity index (CCI), and history of cardiovascular disease was collected...
May 11, 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29757571/localized-chromophobe-renal-cell-carcinoma-preoperative-imaging-judgment-and-laparoscopic-simple-enucleation-for-treatment
#4
Wenbiao Ren, Bichen Xue, Jiandong Qu, Longfei Liu, Chao Li, Xiongbing Zu
OBJECTIVE: To evaluate the preoperative imaging manifestation and therapeutic effect of laparoscopic simple enucleation (SE) for localized chromophobe renal cell carcinoma (chRCC). MATERIALS AND METHODS: Clinical data of 36 patients who underwent laparoscopic SE of localized chRCC at our institute were retrospectively analyzed. All patients underwent preoperative renal protocol CT (unenhanced, arterial, venous, and delayed images). CT scan characteristics were evaluated...
April 30, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29732637/estimated-glomerular-filtration-rate-s-time-to-nadir-after-robot-assisted-partial-nephrectomy-predictors-and-clinical-significance-on-renal-functional-recovery
#5
Glen Denmer Santok, Ali Abdel Raheem, Ki Don Chang, Lawrence Kim, Trenton G Lum, Mohamed Jayed Alenzi, Woong Kyu Han, Young Deuk Choi, Koon Ho Rha
OBJECTIVES: To investigate the impact of postoperative time to nadir of estimated glomerular filtration rate on renal functional changes after robot-assisted partial nephrectomy. METHODS: From 2006 to 2015, 287 patients with renal mass who underwent robot-assisted partial nephrectomy in a referral center were analyzed. The cohort was evaluated based on their time to develop nadir: group 1 (no nadir), group 2 (<48 h) and group 3 (≥48 h). The outcome measures were to evaluate the renal function recovery between groups, risk factors for development of nadir ≥48 h, as well as predictors of chronic kidney disease upstaging...
May 6, 2018: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29723675/retroperitoneal-laparoscopic-nephron-sparing-surgery-for-large-renal-angiomyolipoma-our-technique-and-experience-a-case-series-of-41-patients
#6
Xin Liu, Xin Ma, Qiming Liu, Qingbo Huang, Xintao Li, Baojun Wang, Hongzhao Li, Xu Zhang
OBJECTIVES: To introduce a 'kidney priority' strategy in treating large renal angiomyolipoma (RAML) with retroperitoneal laparoscopic nephron sparing surgery (RLNSS). PATIENTS AND METHODS: From 2010 to 2017, 41 patients with large RAML underwent RLNSS. Distinguished from the standard practice, the kidney was preferentially mobilized and separated from the RAML. Subsequently, it was reconstructed. Finally, the RAML was resected from the perinephric fat. The perioperative variables, surgical technique and complications were reviewed...
April 30, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29698427/intraoperative-ultrasonography-in-laparoscopic-partial-nephrectomy-for-intrarenal-tumors
#7
Baolong Qin, Henglong Hu, Yuchao Lu, Yufeng Wang, Yang Yu, Jiaqiao Zhang, Zhongbiao Zhang, Hongbin Gao, Qing Wang, Shaogang Wang
OBJECTIVE: To evaluate the feasibility and efficacy of intraoperative ultrasonography in laparoscopic partial nephrectomy (LPN) for intrarenal tumors. PATIENTS AND METHODS: All patients who underwent LPN for renal tumors in our institution from January 2010 to October 2016 were assessed retrospectively. Patients were divided into two groups, the first with totally intrarenal tumors (TIT group), defined as a solid renal mass with no exophytic element on both preoperative and intraoperative evaluations, and the second with exophytic tumors (control group)...
2018: PloS One
https://www.readbyqxmd.com/read/29695171/retroperitoneal-robotic-partial-nephrectomy-systematic-review-and-cumulative-analysis-of-comparative-outcomes
#8
Nicola Pavan, Ithaar H Derweesh, Lance Hampton, Wesley White, James Robert Porter, Benjamin Challacombe, Prokar Dasgupta, Riccardo Bertolo, Jihad Kaouk, Vincenzo G Mirone, Francesco Porpiglia, Riccardo Autorino
OBJECTIVES: To compare the outcomes of retroperitoneal versus transperitoneal approach for robot assisted partial nephrectomy (RAPN). MATERIALS AND METHODS: A systematic review of the literature was performed through January 2018 using PubMed, Scopus, and Ovid databases. Article selection proceeded according to the search strategy based on PRISMA criteria. Only studies comparing retroperitoneal to transperitoneal approach for RAPN were deemed eligible for inclusion...
April 26, 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29677080/corm-401-reduces-ischemia-reperfusion-injury-in-an-ex-vivo-renal-porcine-model-of-the-donation-after-cardiac-death
#9
Rabindra N Bhattacharjee, Mahms Richard-Mohamed, Qizhi Sun, Aaron Haig, Ghaleb Aboalsamh, Peter Barrett, Richard Mayer, Ibrahim Alhasan, Karen Pineda-Solis, Larry Jiang, Hajed Alharbi, Manujendra Saha, Eric Patterson, Alp Sener, Gediminas Cepinskas, Anthony M Jevnikar, Patrick P W Luke
BACKGROUND: Carbon monoxide (CO) inhalation protects organ by reducing inflammation and cell death during transplantation processes in animal model. However, using CO in clinical transplantation is difficult due to its delivery in a controlled manner. A manganese-containing CORM-401 has recently been synthesized which can efficiently deliver 3 molar equivalents of CO. We report the ability of this anti-inflammatory CORM-401 to reduce ischemia reperfusion injury associated with prolonged cold storage of renal allografts obtained from donation after cardiac death in a porcine model of transplantation...
April 19, 2018: Transplantation
https://www.readbyqxmd.com/read/29671904/prospective-study-of-robotic-partial-nephrectomy-for-renal-cancer-in-japan-comparison-with-a-historical-control-undergoing-laparoscopic-partial-nephrectomy
#10
Kazushi Tanaka, Jun Teishima, Atsushi Takenaka, Ryoichi Shiroki, Yasuyuki Kobayashi, Kazunori Hattori, Hiro-Omi Kanayama, Shigeo Horie, Yasushi Yoshino, Masato Fujisawa
OBJECTIVES: To evaluate the outcomes of robotic partial nephrectomy compared with those of laparoscopic partial nephrectomy for T1 renal tumors in Japanese centers. METHODS: Patients with a T1 renal tumor who underwent robotic partial nephrectomy were eligible for inclusion in the present study. The primary end-point consisted of three components: a negative surgical margin, no conversion to open or laparoscopic surgery and a warm ischemia time ≤25 min. We compared data from these patients with the data from a retrospective study of laparoscopic partial nephrectomy carried out in Japan...
April 19, 2018: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29668777/combined-effects-of-melatonin-and-topical-hypothermia-on-renal-ischemia-reperfusion-injury-in-rats
#11
Pablo Cambeses Souza, Emanuel Burck Dos Santos, Guilherme Lang Motta, Silvia Regina Bona, Pedro Guilherme Schaefer, Daniela Campagnol, Tiago Bortolini, Carlos Otávio Corso
PURPOSE: To evaluate whether their combination was more effective than either alone in decreasing renal damage due to ischemia/reperfusion (I/R) injury in rats. METHODS: Thirty-two Wistar rats were assigned to four groups. Following right nephrectomy, their left kidneys were subjected to warm ischemia (IR), cold ischemia (TH+IR), intraperitoneal injection of 10 mg/kg melatonin (MEL+IR), or injection of 10 mg/kg melatonin followed by cold ischemia (MEL+TH+IR). Eight randomly assigned right kidneys constituted the control group...
March 2018: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/29664692/comparison-of-short-term-functional-oncological-and-perioperative-outcomes-between-laparoscopic-and-robotic-partial-nephrectomy-beyond-the-learning-curve
#12
Quentin Alimi, Benoit Peyronnet, Philippe Sebe, Jean-François Cote, Solene-Florence Kammerer-Jacquet, Zine-Eddine Khene, Benjamin Pradere, Romain Mathieu, Gregory Verhoest, Bertrand Guillonneau, Karim Bensalah
PURPOSE: To compare the short-term outcomes of robot-assisted partial nephrectomy (RPN) and laparoscopic partial nephrectomy (LPN) when performed by highly experienced surgeons. METHODS: A prospective multicenter study was conducted, including the 50 last patients having undergone LPN and RPN for T1-T2 renal tumors in two institutions between 2013 and 2016, performed by two different surgeons with an experience of over 200 procedures each in LPN and RPN, respectively, at the beginning of the study...
April 17, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29611214/hydrogen-gas-does-not-ameliorate-renal-ischemia-reperfusion-injury-in-a-preclinical-model
#13
Sarah A Hosgood, Tom Moore, Maria Qurashi, Tom Adams, Michael L Nicholson
In renal transplantation, ischemia reperfusion injury impairs early graft function and can reduce long term graft survival. Hydrogen has antioxidant and anti-inflammatory properties that can reduce the effects of ischemic injury. The aim of this study was to examine the effects of hydrogen gas administered during reperfusion in a preclinical model of kidney ischemia reperfusion injury. Porcine kidneys underwent 15 min of warm ischemia followed by 22 h of cold ischemia. They were then reperfused for 6 h with whole autologous blood on an ex vivo reperfusion circuit...
April 2, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29607529/transplantation-of-cold-stored-porcine-kidneys-after-controlled-oxygenated-rewarming
#14
Anja Gallinat, Jing Lu, Charlotte von Horn, Moritz Kaths, Marc Ingenwerth, Andreas Paul, Thomas Minor
The concept of "controlled oxygenated rewarming" (COR) using ex vivo machine perfusion after cold storage was evaluated as tool to improve renal graft function after transplantation. Renal function after 20 min warm ischemia and 21 h cold storage was studied in an auto-transplant model in pigs (25-30 kg, n = 6 per group). In the study group, preimplant ex vivo machine perfusion for 90 min was added after cold storage, including gentle warming up of the graft to 20°C (COR). Kidneys that were only cold stored for 21 h served as controls...
April 1, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29579845/results-of-controlled-donation-after-circulatory-death-in-a-third-level-hospital
#15
N Palomo-López, L Martín-Villén, Á J Roldán-Reina, Z Ruiz de Azúa-López, D X Cuenca-Apolo, M Adriaensens-Pérez, Y Corcia-Palomo, J J Egea-Guerrero
OBJECTIVE: To investigate the characteristics and evolution of controlled donation after circulatory death (DCD) type III. MATERIALS AND METHODS: Observational and retrospective study of controlled DCD type III of donors conducted from 2014 to 2016. Clinical data, intensive care unit (ICU) stay, cause of death, warm ischemia time, and total time were collected. Delayed graft function (DGF) and survival of renal transplant were also registered. Qualitative variables are described as frequencies and absolute values and quantitative variables as medians and interquartile ranges...
March 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29551485/the-perioperative-outcomes-between-renal-hilar-and-non-hilar-tumors-following-robotic-assisted-partial-nephrectomy-rapn
#16
Shih-Yen Lu, Hsiao-Jen Chung, Eric Yi-Hsiu Huang, Tzu-Pin Lin, Alex T L Lin
BACKGROUND: The aim of this study was to compare the perioperative outcomes between renal hilar tumors and non-hilar tumors after robotic-assisted partial nephrectomy (RAPN). METHODS: A retrospective review of consecutive patients who underwent RAPN from December 2009 to September 2015 at our institution was recruited. Perioperative outcomes including demographic characteristics, perioperative, pathological and renal function outcomes were compared between the hilar group (n = 30) and non-hilar group (n = 170)...
March 15, 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29517951/knotless-retroperitoneoscopic-nephron-sparing-surgery-for-small-renal-masses-comparison-of-bipolar-sutureless-technique-and-barbed-suture-technique
#17
Jianfei Ye, Shudong Zhang, Xiaojun Tian, Guoliang Wang, Lei Zhao, Lulin Ma
Objective Laparoscopic knot-tying and suturing are the most difficult steps in shortening the warm ischemia time and learning curve of laparoscopic nephron-sparing surgery. This study was performed to demonstrate the safety, oncological efficacy, and technical tips of sutureless retroperitoneal laparoscopic nephron-sparing surgery (RPNSS). Methods This retrospective study included 78 cases of RPNSS using a sutureless technique and 126 cases of RPNSS using a single-layer barbed self-retaining suture technique performed from December 2012 to December 2016...
April 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29510690/mannitol-reduces-nephron-loss-after-warm-renal-ischemia-in-a-porcine-model
#18
José A Damasceno-Ferreira, Leonardo A S Abreu, Gustavo R Bechara, Waldemar S Costa, Marco A Pereira-Sampaio, Francisco J B Sampaio, Diogo B De Souza
BACKGROUND: Mannitol has been employed to ameliorate renal warm ischemia damage during partial nephrectomy, however, there is limited scientific evidence to support the use of mannitol during partial nephrectomy. The objective of the present study was to investigate the glomerular number after renal warm ischemia, with and without the use of mannitol in a Pig Model. METHODS: Twenty-four male pigs were assigned into three groups. Eight animals were allocated to the sham group that was subjected to laparoscopic dissection of the left renal hilum, without renal ischemia...
March 6, 2018: BMC Urology
https://www.readbyqxmd.com/read/29502053/-a-high-level-of-high-density-lipoprotein-cholesterol-is-a-protective-factor-against-transplant-renal-artery-stenosis
#19
Yan-Na Liu, Li-Xin Yu, Wen-Feng Deng, Kai-Qun Li, Ru-Min Liu, Gui-Rong Ye, Fang-Xiang Fu, Jiang-Tao Li, Yun Miao
OBJECTIVE: To investigate the factors associated with the occurrence of transplant renal artery stenosis (TRAS). METHODS: A retrospective analysis was conducted in 26 recipients who developed TRAS and 40 concurrent renal recipients without TRAS. We also conducted a nested case-control study in 14 patients with TRAS (TRAS-SD group) and another 14 non-TRAS recipients who received the allograft from the same donor (non-TRAS-SD group). RESULTS: Compared with those in the concurrent recipients without TRAS, acute rejection (AR) occurred at a significantly higher incidence (P=0...
February 20, 2018: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/29493436/trifecta-and-pentafecta-rates-after-robotic-assisted-partial-nephrectomy-comparative-study-of-patients-with-renal-masses-4-and-%C3%A2-4-cm
#20
Roberto Castellucci, Giulia Primiceri, Pietro Castellan, Michele Marchioni, Carlo D'Orta, Francesco Berardinelli, Fabio Neri, Luca Cindolo, Luigi Schips
OBJECTIVES: Robotic-assisted partial nephrectomy (RAPN) is preferred to radical nephrectomy because it guarantees superior functional outcomes in patients with small renal masses (RMs). Only a few studies so far have evaluated the feasibility of RAPN for the treatment of RM ≥4 cm. The aim of this study is to evaluate the safety and feasibility of RAPN based on a comparison of trifecta and pentafecta rates for RMs ≥4 cm. MATERIAL AND METHODS: We retrospectively analyzed prospectively collected data from an institutional database of patients undergoing RAPN from September 2013 to November 2016...
March 1, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
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