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renal warm ischemia

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https://www.readbyqxmd.com/read/28503809/robot-assisted-laparoscopic-versus-open-partial-nephrectomy-in-patients-with-chronic-kidney-disease-a-propensity-score-matched-comparative-analysis-of-surgical-outcomes
#1
Toshio Takagi, Tsunenori Kondo, Hidekazu Tachibana, Junpei Iizuka, Kenji Omae, Hirohito Kobayashi, Kazuhiko Yoshida, Kazunari Tanabe
OBJECTIVES: To compare surgical outcomes between robot-assisted laparoscopic partial nephrectomy and open partial nephrectomy in patients with chronic kidney disease. METHODS: Of 550 patients who underwent partial nephrectomy between 2012 and 2015, 163 patients with T1-2 renal tumors who had an estimated glomerular filtration rate between 30 and 60 mL/min/1.73 m(2) , and underwent robot-assisted laparoscopic partial nephrectomy or open partial nephrectomy were retrospectively analyzed...
May 14, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28500075/overexpression-of-human-cd55-and-cd59-or-treatment-with-human-cd55-protects-against-renal-ischemia-reperfusion-injury-in-mice
#2
Anjan K Bongoni, Bo Lu, Evelyn J Salvaris, Veena Roberts, Doreen Fang, Jennifer L McRae, Nella Fisicaro, Karen M Dwyer, Peter J Cowan
Deficiency in the membrane-bound complement regulators CD55 and CD59 exacerbates renal ischemia-reperfusion injury (IRI) in mouse models, but the effect of increasing CD55 and CD59 activity has not been examined. In this study, we investigated the impact of overexpression of human (h) CD55 ± hCD59 or treatment with soluble rhCD55 in a mouse model of renal IRI. Unilaterally nephrectomised mice were subjected to 18 (mild IRI) or 22 min (moderate IRI) warm renal ischemia, and analyzed 24 h after reperfusion for renal function (serum creatinine and urea), complement deposition (C3b/c and C9), and infiltration of neutrophils and macrophages...
May 12, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28495618/a-model-of-acute-renal-allograft-rejection-in-outbred-yorkshire-piglets
#3
Randi Lassiter, Youli Wang, Xuexiu Fang, Matt Winn, Arina Ghaffari, Chak-Sum Ho, Sandra Helman, Ryan Jajosky, Daniel Kleven, N Stanley Nahman, Todd D Merchen
Pigs represent a desirable animal model for the study of rejection in kidney transplantation with inbred Yucatan miniature swine (YMS) the most commonly studied strain due to well defined swine leukocyte antigen (SLA) genotypes. However, limitations to YMS may include cost and availability. Outbred Yorkshire pigs are widely available and significantly cheaper than YMS. Recent advances in SLA genotyping have allowed its application to outbred strains. On this basis, we theorized that Yorkshire pigs would be a viable alternative to YMS for the study of rejection in kidney transplantation...
May 8, 2017: Transplant Immunology
https://www.readbyqxmd.com/read/28464554/does-training-of-fellows-affect-peri-operative-outcomes-of-robot-assisted-partial-nephrectomy
#4
Zine-Eddine Khene, Benoit Peyronnet, Elise Bosquet, Benjamin Pradère, Corentin Robert, Tarek Fardoun, Solène-Florence Kammerer-Jacquet, Grégory Verhoest, Nathalie Rioux-Leclercq, Romain Mathieu, Karim Bensalah
OBJECTIVE: To evaluate the impact of fellows' involvement on the peri-operative outcomes of robot-assisted partial nephrectomy (RAPN). MATERIALS AND METHODS: We analysed 216 patients who underwent RAPN for a small renal tumour. We stratified our cohort into two groups according to the involvement of a fellow surgeon during the procedure: expert surgeon operating alone (expert group) and fellow operating under the supervision of the expert surgeon (fellow group)...
May 2, 2017: BJU International
https://www.readbyqxmd.com/read/28463678/laparoscopic-donor-nephrectomy-of-dual-renal-artery-kidneys-single-center-experience
#5
Ibrahim Al-Oraifi, Mansour Tawfeeq, Hamad Al-Hellow, Mohammed S Al-Qahtani, Meteb M Al-Bugami, Abdulwahab Al-Shahrani, Gelu Osian
Background: Multiple renal artery (MRA) kidneys represent a special challenge for surgeons, during both donor nephrectomy and renal transplantation. AIMS: This study aims to evaluate both donors and recipients outcomes of laparoscopically procured dual renal artery (DRA) kidneys. Patients and Methods: We reviewed the medical records of all living kidney donors who underwent laparoscopic donor nephrectomy between April 2009 and December 2014, and their recipients. Operative details and immediate outcomes of both donors and recipients of DRA kidneys were compared to those of donors and recipients of single renal artery (SRA) kidneys...
March 2017: Chirurgia
https://www.readbyqxmd.com/read/28407628/super-selective-artery-embolization-before-laparoscopic-partial-nephrectomy-in-treating-renal-angiomyolipoma
#6
Chao Qin, YiChun Wang, Pengchao Li, Pu Li, Jun Tao, Pengfei Shao, Qiang Lv
INTRODUCTION: To investigate the feasibility and efficiency of super-selective artery embolization (SAE) before laparoscopic partial nephrectomy (LPN) in treating renal angiomyolipoma (RAML). MATERIALS AND METHODS: A retrospective analysis was conducted on 36 consecutive patients who underwent SAE before LPN (group A, n = 16) or LPN directly (group B, n = 20) from June 2010 to March 2016. Intraoperative blood loss, blood transfusion, operation time, warm ischemia time (WIT), and prognosis were compared between groups...
April 14, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28387661/effectiveness-and-safety-of-laparoscopic-enucleation-combined-with-selective-arterial-embolization-for-renal-angiomyolipoma
#7
Dong Wang, Han-Zhong Li, Zhi-Gang Ji
OBJECTIVE: This study aims to investigate the clinical value of laparoscopic enucleation combined with selective arterial embolization for the treatment of renal angiomyolipoma. METHODS: Data of patients who underwent laparoscopic nephron-sparing surgery for renal angiomyolipoma between July 2013 and November 2014 in our center were analyzed. RESULTS: Before surgery, 19 patients underwent selective arterial embolization, while 24 patients did not receive this treatment...
March 31, 2017: Cancer Biomarkers: Section A of Disease Markers
https://www.readbyqxmd.com/read/28379673/hilar-parenchymal-oversew-a-novel-technique-for-robotic-partial-nephrectomy-hilar-tumor-renorrhaphy
#8
Jaya Sai S Chavali, Ryan Nelson, Matthew J Maurice, Onder Kara, Pascal Mouracade, Julien Dagenais, Jeremy Reese, Pilar Bayona, Georges-Pascal Haber, Robert J Stein
INTRODUCTION: A renorrhaphy technique which is effective for hemostasis but does not place undue tension on the branch vessels of the renal sinus remains one of the challenging steps after hilar tumor resection during robotic partial nephrectomy (RPN). The published V-hilar suture (VHS) technique is one option for reconstruction after an RPN involving the hilum. The objective of this video is to show a novel renorrhaphy technique, Hilar Parenchymal Oversew that has been effective for such cases...
April 6, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28379667/laparoscopic-donor-nephrectomy-in-unusual-venous-anatomy-donor-and-recepient-implications
#9
Avinash Bapusaheb Patil, Tarun Dilip Javali, Harohalli K Nagaraj, S M L Prakash Babu, Arvind Nayak
OBJECTIVES: Laparoscopic donor nephrectomy is now a commonly performed procedure in most of renal transplantation centers. However, the suitability of laparoscopy for donors with abnormal venous anatomy is still a subject of debate. MATERIALS AND METHODS: Between August 2007 and August 2014, 243 laparoscopic donor nephrectomies were performed in our institution. All donors were evaluated with preoperative three-dimensional spiral computed tomography (CT) angiography Thirteen (5...
April 6, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28355603/glomerular-morphology-and-renal-function-after-warm-ischemia-by-main-artery-or-selective-clamping-in-a-porcine-model
#10
Gustavo R Bechara, José A Damasceno-Ferreira, Leonardo A S Abreu, Waldemar S Costa, Francisco J B Sampaio, Marco A Pereira-Sampaio, Diogo B de Souza
OBJECTIVE: The study aimed to evaluate the ischemic and non-ischemic areas after selective arterial occlusion by using stereological analysis of glomeruli, and to compare them with main arterial clamping and sham-operated animals. MATERIALS AND METHODS: Twenty-four male pigs were used in the study. The animals were divided into 3 groups with 8 animals in each as follows: group sham, submitted to laparoscopic dissection of the renal pedicle but not submitted to ischemia; group arterial (A), submitted to left renal artery clamping; and group selective (S), submitted to left renal artery caudal branch occlusion...
March 30, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28352149/robot-assisted-partial-nephrectomy-for-t1b-tumors-strict-trifecta-outcomes
#11
Ilter Tufek, Panagiotis Mourmouris, Tunkut Doganca, Can Obek, Omer Burak Argun, Mustafa Bilal Tuna, Mehmet Selcuk Keskin, Ali Rıza Kural
BACKGROUND AND OBJECTIVES: "Trifecta" in partial nephrectomy consists of negative surgical margins, minimal renal function decrease and absence of complications. In the present article, our single-center robot-assisted partial nephrectomy (RAPN) experience in T1b renal masses is reported in terms of strict Trifecta outcomes. METHODS: This is a retrospective analysis of patients with a tumor diameter between 4 and 7 cm (stage T1b), who underwent RAPN by a single surgeon...
January 2017: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/28340844/anatomic-diversity-encountered-during-laparoscopic-hand-assisted-transperitoneal-donor-nephrectomy-a-case-report-of-complete-caval-duplication
#12
S L Kirecci, M Demir, M Ilgi, M Battal, A I Dokucu, A Unsal
INTRODUCTION: Laparoscopic donor nephrectomy is widely used to retrieve a kidney for transplantation. Preoperative evaluation of the donor is of crucial importance to the recipient. In particular, vascular anatomy should be assessed with the help of modern imaging modalities. We present a hand-assisted laparoscopic nephrectomy of a kidney donor with a complete duplex vena cava. CASE REPORT: A 40-year-old male patient was admitted to our clinic as a kidney donor for his 20-year-old son...
April 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28340802/comparison-of-two-different-laparoscopic-donor-nephrectomy-with-vaginal-extraction-techniques-a-single-center-experience
#13
A H Karayagiz, T Erturk, U Cakir, I Berber
OBJECTIVE: The aim of this study was to compare the results of standard laparoscopic donor nephrectomy with vaginal extraction (SLDN-VE) and laparoendoscopic single-site donor nephrectomy with vaginal extraction (LESSDN-VE). METHODS: We analyzed the data of 95 female donors who underwent SLDN-VE (group I; n = 87) and LESSDN-VE (group II; n = 8) in our center. Parameters regarding donor age, body mass index (BMI), length of hospitalization, duration of surgical procedure, amount of blood loss, warm and cold ischemia times, side of graft nephrectomy, number of renal arteries and veins, postoperative visual analog pain scores at 6th and 12th hours (VAS6, VAS12), peri-and postoperative complications of donors and recipients, and graft function at discharge and follow-up were compared between the 2 groups...
April 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28326799/glomerular-loss-after-renal-radiofrequency-ablation-are-comparable-to-30-minutes-of-warm-ischemia
#14
Leonardo Albuquerque Dos Santos Abreu, José Aurelino Damasceno-Ferreira, Waldemar Silva Costa, Marco Aurélio Pereira-Sampaio, Francisco José Barcellos Sampaio, Diogo Benchimol de Souza
PURPOSE: To compare, with stereological methods, the glomerular loss in kidneys submitted to radiofrequency ablation (RFA) or warm ischemia. MATERIALS AND METHODS: Twenty-six male pigs were divided into three groups. Eight animals were allocated in the sham group, which was submitted to laparoscopic dissection of the left renal hilum, without renal ischemia. Eight animals were allocated in the ischemia group, which had the left renal hilum clamped for 30 minutes under laparoscopic access...
May 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28315787/the-synergistic-influence-of-ischemic-time-and-surgical-precision-on-acute-kidney-injury-after-robotic-partial-nephrectomy
#15
Julien Dagenais, Matt Maurice, Pascal Mouracade, Onder Kara, Ryan Nelson, Ercan Malkoc, Jihad Kaouk
OBJECTIVES: To examine the dynamic and potentially synergistic influence of warm ischemia time (WIT) and excisional volume loss (EVL) on predicted rates of post-partial acute kidney injury (AKI) across a range of tumor complexities. To investigate whether these modifiable variables sensitize the kidney to the other's damaging influence. METHODS: We retrospectively reviewed 1,245 patients between 2006 and 2016 with bilateral kidneys and enhancing renal masses in our single-institution robotic partial nephrectomy (PN) database...
March 15, 2017: Urology
https://www.readbyqxmd.com/read/28304214/retroperitoneal-laparoscopic-partial-nephrectomy-for-tumors-larger-than-7%C3%A2-cm-in-renal-cell-carcinoma-initial-experience-of-single-institution
#16
Erlin Song, Xin Ma, Ruihua An, Peng Zhang, Xu Zhang, Baojun Wang, Taoping Shi, Shengkun Sun
BACKGROUND: To report our initial experience dealing with retroperitoneal laparoscopic partial nephrectomy (LPN) for tumors larger than 7 cm in renal cell carcinoma (RCC). MATERIALS AND METHODS: A total of 15 patients with malignant tumors larger than 7 cm underwent retroperitoneal LPN at our institution. Patient baseline demographics, perioperative outcomes, pathological characteristics, and estimated glomerular filtration rate (eGFR) were analyzed retrospectively in our collected database...
March 17, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28303428/outcomes-of-laparoscopic-and-robotic-partial-nephrectomy-for-large-4%C3%A2-cm-kidney-tumors-systematic-review-and-meta-analysis
#17
REVIEW
Nicola Pavan, Ithaar H Derweesh, Carme Maria Mir, Giacomo Novara, Lance J Hampton, Matteo Ferro, Sisto Perdonà, Dipen J Parekh, Francesco Porpiglia, Riccardo Autorino
PURPOSE: The aim of this study was to assess the outcomes of minimally invasive (laparoscopic and robotic) partial nephrectomy (MIPN) for large renal masses. MATERIALS AND METHODS: A systematic literature review was performed up to September 2016 using multiple search engines to identify studies comparing MIPN for tumors larger than 4 cm (>cT1a) with MIPN for tumors smaller than 4 cm (cT1a). The preferred reporting items for systematic reviews and meta-analyses (PRISMA) criteria were used for article selection...
March 16, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28279366/-impact-of-robotic-assistance-on-the-use-and-the-outcomes-of-nephron-sparing-surgery-a-single-center-experience
#18
T Fardoun, B Peyronnet, E Oger, G Verhoest, R Mathieu, Z Khene, B Pradere, Q Alimi, A Manunta, N Rioux-Leclercq, J-J Patard, S-F Kammerer-Jacquet, K Bensalah
INTRODUCTION: The aim of this study was to assess the impact of the acquisition of a Da Vinci(®) robot on the use and outcomes of partial nephrectomy (PN). PATIENTS AND METHODS: It was a single center retrospective study including 280 patients who underwent PN from January 2006 to May 2013. The number of PN, tumors and patients' characteristics and perioperative outcomes have been assessed over 3 periods defined according to the main surgical approach: 2006-2008 (open PN), 2008-2010 (laparoscopic PN) and 2010-2013 (robotic PN)...
December 2016: Progrès en Urologie
https://www.readbyqxmd.com/read/28270958/laparoscopic-donor-nephrectomy-complications-and-management-a-single-center-experience
#19
Volkan Tuğcu, Selçuk Şahin, İsmail Yiğitbaşı, Nevzat Can Şener, Fatih Gökhan Akbay, Ali İhsan Taşçı
OBJECTIVE: To present our experience with laparoscopic donor nephrectomy (LDN), our complications and management modalities. Material and methods: Fifty-one transperitoneal LDNs performed in our clinic between the years 2011, and 2015, were evaluated retrospectively. Demographic characteristics of the patients, operative and postoperative data and complications were evaluated. RESULTS: Nineteen female and 32 male patients with ages ranging from 24 to 65 years underwent left- (n=44), and right-sided (n=7) LDNs...
March 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28259374/supplemental-oxygen-during-hypothermic-kidney-preservation-a-systematic-review
#20
REVIEW
J M O'Callaghan, K T Pall, Lhm Pengel
We reviewed the evidence for ex-vivo Supplemental Oxygen during Hypothermic preservation (SOH) for deceased donor kidneys. Bibliographic databases were searched for human and animal studies of SOH in kidney transplantation reporting on patient or animal survival rate, discard rate, technical complications or renal function outcomes. We make special reference to a specific subgroup: supplemental oxygen applied during cold perfusion, referred to as Hypothermic Oxygenated Perfusion (HOP). Four human and 25 animal studies were identified...
February 17, 2017: Transplantation Reviews
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