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Medical device

David L Tirschwell, Mark Turner, David Thaler, James Choulerton, David Marks, John Carroll, Lee MacDonald, Richard W Smalling, Maria Koullick, Ning Yan Gu, Jeffrey L Saver
OBJECTIVE: Compared to medical therapy alone, percutaneous closure of patent foramen ovale (PFO) further reduces risk of recurrent ischemic strokes in carefully selected young to middle-aged patients with a recent cryptogenic ischemic stroke. The objective of this study was to evaluate the cost-effectiveness of this therapy in the context of the United Kingdom (UK) healthcare system. METHODS: A Markov cohort model consisting of 4 health states (Stable after index stroke, Post-Minor Recurrent Stroke, Post-Moderate Recurrent Stroke, and Death) was developed to simulate the economic outcomes of device-based PFO closure compared to medical therapy...
March 22, 2018: Journal of Medical Economics
Hassan Hashemi, Mehdi Khabazkhoob, Payam Nabovati, Negareh Yazdani, Hadi Ostadimoghaddam, Ehsan Shiralivand, Akbar Derakhshan, AbbasAli Yekta
Purpose: To determine the normal range of intraocular pressure (IOP) in the young and its association with certain corneal parameters using a non-contact device. Methods: Subjects were selected from students of Mashhad University of Medical Sciences through stratified sampling. All participants had visual acuity testing, corneal imaging, a comprehensive slit-lamp examination by an ophthalmologist, and IOP measurement using a non-contact air-puff tonometer. Results: Of the 1280 invitees, 1073 (83...
March 2018: Journal of Current Ophthalmology
Jeong Hee Lee, Eung Do Kim, Eun Jung Jun, Hyoung Sun Yoo, Joon Woo Lee
Background: The purpose of this paper is to provide technology trends and information regarding market and prospects in stents used for human blood vessels in Korea and the world.A stent is a medical device in the form of a cylindrical metal net used to normalize flow when blood or other bodily fluids such as biliary fluids are obstructed in blood vessels, gastrointestinal tracts, etc. by inserting the stent into a narrowed or clogged area. Stents are classified into vascular and non-vascular stents...
2018: Biomaterials Research
Saioa Burgui, Carmen Gil, Cristina Solano, Iñigo Lasa, Jaione Valle
Two-component systems (TCS) are modular signal transduction pathways that allow cells to adapt to prevailing environmental conditions by modifying cellular physiology. Staphylococcus aureus has 16 TCSs to adapt to the diverse microenvironments encountered during its life cycle, including host tissues and implanted medical devices. S. aureus is particularly prone to cause infections associated to medical devices, whose surfaces coated by serum proteins constitute a particular environment. Identification of the TCSs involved in the adaptation of S...
2018: Frontiers in Microbiology
Benjamin Rémy, Sonia Mion, Laure Plener, Mikael Elias, Eric Chabrière, David Daudé
Numerous bacteria utilize molecular communication systems referred to as quorum sensing (QS) to synchronize the expression of certain genes regulating, among other aspects, the expression of virulence factors and the synthesis of biofilm. To achieve this process, bacteria use signaling molecules, known as autoinducers (AIs), as chemical messengers to share information. Naturally occurring strategies that interfere with bacterial signaling have been extensively studied in recent years, examining their potential to control bacteria...
2018: Frontiers in Pharmacology
Akihide Konishi, Mami Ho, Yuko Shirai, Haruki Shirato
A prospective randomized clinical trial showed that the BioFreedom stent (Biosensors International), which is a polymer-free and carrier-free drug-coated stent, was significantly superior to a bare-metal stent (BMS) in patients at high bleeding risk who were receiving a 1-month course of dual antiplatelet therapy (DAPT). However, the stent thrombosis rate (2.01% for BioFreedom vs. 2.20% for BMS) was 4-6-fold higher than that of approved drug-eluting stents based on real-world data in Japan. Furthermore, the frequency of stent thrombosis at more than 1 month with the BioFreedom stent was slightly higher than that at less than 1 month...
March 21, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
Saadia Sherazi, Peter Kouides, Charles Francis, Charles Julian Lowenstein, Majed Refaai, Grace Conley, Brent Alan Johnson, Eugene Muchnik, Susan Lien, Howard Todd Massey, Jeffrey Dean Alexis
BACKGROUND: Bleeding is a major cause of morbidity in patients with continuous flow left ventricular assist devices (LVADs). We sought to identify clinical predictors of bleeding within the first year of LVAD implantation. METHODS: A prospective study was performed on 30 patients with HeartMate II implantation at the University of Rochester Medical Center, Rochester, New York, United States. Blood was collected within 1 week before implantation, and at 1, 3, and 30 ± 10 days after implantation...
March 1, 2018: International Journal of Artificial Organs
Y Gao, Y C Liang, H B Yu, X L Yan, B G Xu, R Liu, N Wang, G Q Xu, Z L Wang
Objective: To investigate the heart rate control situation of chronic heart failure (CHF) patients who received cardiovascular implantable electronic device (CIED) therapy, and to assess the heart rate control efficacy by optimized medication adjustment. Methods: We performed a perspective study in heart failure with reduced left ventricular ejection fraction (HFrEF) patients who received CIED according to guideline recommendations, patients were enrolled from January 2012 to January 2017. Resting heart rate (RHR) recorded by electrocardiogram after 10 minutes' rest and medication usage within 1 month were recorded at baseline...
March 24, 2018: Zhonghua Xin Xue Guan Bing za Zhi
Andres Canales, Seongjun Park, Antje Kilias, Polina Anikeeva
Multifunctional devices for modulation and probing of neuronal activity during free behavior facilitate studies of functions and pathologies of the nervous system. Probes composed of stiff materials, such as metals and semiconductors, exhibit elastic and chemical mismatch with the neural tissue, which is hypothesized to contribute to sustained tissue damage and gliosis. Dense glial scars have been found to encapsulate implanted devices, corrode their surfaces, and often yield poor recording quality in long-term experiments...
March 21, 2018: Accounts of Chemical Research
Eloise G Harrison, Jennifer L Keating, Prue E Morgan
INTRODUCTION: Restless legs syndrome (RLS) is a sensorimotor disorder characterised by an uncomfortable urge to move the legs. Management is primarily pharmacological. Effects for non-pharmacological, non-surgical options are published but lack systematic examination. OBJECTIVES: To synthesise results of non-pharmacological/non-surgical treatment compared to no-treatment controls or alternative treatment for RLS on any relevant outcome. METHODS: Databases and reference lists of reviews were searched for randomised controlled trials (RCTs) comparing non-pharmacological treatment to alternative or no treatment controls for idiopathic RLS...
March 21, 2018: Disability and Rehabilitation
Benoît Brouard
According to the report ?The Internet of Things Market? the number of connected devices will reach 68 billion in 2020. In 2012, the total amount of data was 500 petabytes. So, after the race to increase power computation, now the stake is in the capacity to store all these data in the cloud, to open their access and to analyze these data properly. The use of these data is a major challenge for medical research and public health.
October 27, 2017: Journal International de Bioéthique et D'éthique des Sciences
Jing Sun, Wenhui Zhou, Haibo Yang, Xue Zhen, Longfei Ma, Dirk Williams, Xudong Sun, Ming-Fei Lang
The development of flexible and transparent devices requires completely transparent and flexible circuits (TFCs). To overcome the disadvantages of the previously reported TFCs that are partially transparent, lacking pattern control, or labor consuming, we achieve true TFCs via a facile process with precise pattern control, exhibiting concurrent high transparency, conductivity, flexibility, stretchability, and robustness. A highly transparent and flexible conductive film is first made through spin coating silver nanowires (AgNWs) onto polydimethylsiloxane (PDMS), and demonstrates simultaneous high transparency (90...
March 21, 2018: Chemical Communications: Chem Comm
Diego de Souza Gonçalves, Marina da Silva Ferreira, Susie Coutinho Liedke, Kamilla Xavier Gomes, Gabriel Afonso de Oliveira, Pedro Ernesto Lopes Leão, Gabriele Vargas Cesar, Sergio H Seabra, Juliana Reis Cortines, Arturo Casadevall, Leonardo Nimrichter, Gilberto Barbosa Domont, Magno Rodrigues Junqueira, Jose Mauro Peralta, Allan J Guimaraes
Acanthamoeba castellanii (Ac) are ubiquitously distributed in nature, and by contaminating medical devices such as heart valves and contact lenses, they cause a broad range of clinical presentations to humans. Although several molecules have been described to play a role in Ac pathogenesis, including parasite host-tissue invasion and escaping of host-defense, little information is available on their mechanisms of secretion. Herein, we describe the molecular components secreted by Ac, under different protein availability conditions to simulate host niches...
March 21, 2018: Virulence
Myung Gyu Song, Tae-Seok Seo, Yun Hwan Kim, Sung Bum Cho, Hwan Hoon Chung, Seung Hwa Lee, Euichul Jung
The effect of catheter diameter on left innominate vein stenosis in breast cancer patients after totally implantable venous access port placement. PURPOSE: To evaluate the effect of catheter diameter on left innominate vein stenosis in breast cancer patients after placement of totally implantable venous access ports. MATERIALS AND METHODS: Totally implantable venous access ports were placed via the left internal jugular vein in 241 women with right breast cancer from January 2010 to December 2014 (mean age, 51...
March 1, 2018: Journal of Vascular Access
Azuma Takahashi, Xiaodong Zhu, Yusuke Aoyama, Mitsuo Umezu, Kiyotaka Iwasaki
The evaluation of strain induced in a blood vessel owing to contact with a medical device is of significance to examine the causes leading to vascular injury and rupture. The development of a method to assess strain in largely deformed elastic materials is expected. This study's scope was to measure strain in deformed tubular elastic mock vessels using tomographic particle image velocimetry (tomo-PIV), and to show the applicability of this measurement method by comparing the results with data derived from a finite element analysis (FEA)...
March 20, 2018: Cardiovascular Engineering and Technology
César Calvo-Lobo, Francisco Unda-Solano, Daniel López-López, Irene Sanz-Corbalán, Carlos Romero-Morales, Patricia Palomo-López, Jesús Seco-Calvo, David Rodríguez-Sanz
Purpose: This study aim was to compare the effectiveness of the median nerve neural mobilization (MNNM) and cervical lateral glide (CLG) intervention versus oral ibuprofen (OI) in subjects who suffer cervicobrachial pain (CP). Methods: This investigation was a, multicenter, blinded, randomized controlled clinical trial (NCT02595294; NCT02593721). A number of 105 individuals diagnosed with CP were enrolled in the study and treated in 2 different medical facilities from July to November 2015. Participants were recruited and randomly assigned into 3 groups of 35 subjects...
2018: International Journal of Medical Sciences
Salil Sidharthan Karipott, Bradley D Nelson, Robert E Guldberg, Keat Ghee Ong
Implantable wireless sensors have been used for real-time monitoring of chemicals and physical conditions of bones, tendons and muscles to diagnose and study orthopedic diseases and injuries. Due to the importance of these sensors in orthopedic care, a critical review, which not only analyzes the underlying technologies but also their clinical implementations and challenges, will provide a landscape view on their current state and their future clinical role. Areas covered: By conducting an extensive literature search and following the leaders of orthopedic implantable wireless sensors, this review covers the battery-powered and battery-free wireless implantable sensor technologies, and describes their implementation for hips, knees, spine, and shoulder stress/strain monitoring...
March 21, 2018: Expert Review of Medical Devices
Ali Hassan Sodhro, Arun Kumar Sangaiah, Gul Hassan Sodhro, Sonia Lohano, Sandeep Pirbhulal
Rapid progress and emerging trends in miniaturized medical devices have enabled the un-obtrusive monitoring of physiological signals and daily activities of everyone's life in a prominent and pervasive manner. Due to the power-constrained nature of conventional wearable sensor devices during ubiquitous sensing (US), energy-efficiency has become one of the highly demanding and debatable issues in healthcare. This paper develops a single chip-based wearable wireless electrocardiogram (ECG) monitoring system by adopting analog front end (AFE) chip model ADS1292R from Texas Instruments...
March 20, 2018: Sensors
Ariel F Pomputius
Wellness-the balance of mental, emotional, spiritual, and physical health for the overall health benefit of the individual-is a growing concern, particularly for professionals in the medical field. Although wellness is usually viewed in opposition to technology, more digital devices and mobile applications are emerging to support wellness for health consumers. This wellness technology seeks to improve the overall health of the user through increasing calm and decreasing stress. This column will explain what wellness technology is, concerns over its widespread application, examples of wellness devices on the market currently, and an overview of where it is being applied in libraries...
April 2018: Medical Reference Services Quarterly
Suzanne Schwartz, Aftin Ross, Seth Carmody, Penny Chase, Steve Christey Coley, Julie Connolly, Cathy Petrozzino, Margie Zuk
No abstract text is available yet for this article.
March 2018: Biomedical Instrumentation & Technology
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