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https://www.readbyqxmd.com/read/29223760/down-the-local-a-qualitative-case-study-of-daytime-drinking-spaces-in-the-london-borough-of-islington
#1
Claire Thompson, Sarah Milton, Matt Egan, Karen Lock
BACKGROUND: Recognising the lack of research on daytime drinking practices in areas with managed night-time economies (NTEs), this qualitative study explores the phenomena in the London Borough of Islington; a rapidly gentrifying area with a highly regulated night-time economy (NTE). The objectives were to (i) Characterise the daytime drinking spaces of the local alcohol environment and (ii) Theorise the ways in which these spaces, and the practices and performativities within them, are situated within broader social and economic trends...
December 7, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29223658/can-technology-really-help-to-reduce-underage-drinking-new-evidence-on-the-effects-of-false-id-laws-with-scanner-provisions
#2
Emily Yiying Zheng
In Volume 36 of this journal, Yoruk (2014) uses data from the National Longitudinal Survey of Youth 1997 and finds that false ID laws with scanner provisions have large impacts on binge drinking participation, frequency of alcohol consumption and binge drinking frequency among minors. This paper reexamines how false ID laws with scanner provisions affect underage drinking. I first demonstrate that analyses based on NLSY97 data fail falsification exercises testing for significant pre-intervention effects, and that the estimated effects based on these data are highly sensitive to the inclusion of a lead term and to sample selection, which weakens confidence in the large estimated effects reported in Yoruk (2014)...
November 16, 2017: Journal of Health Economics
https://www.readbyqxmd.com/read/29223527/low-doses-of-prenatal-ethanol-exposure-and-maternal-separation-alter-hpa-axis-function-and-ethanol-consumption-in-adult-male-rats
#3
F Biggio, G Talani, V Locci, M G Pisu, G Boero, B Ciarlo, D R Grayson, M Serra
Adverse maternal behaviors during pregnancy and unfavorable postnatal experiences during development are associated with an increased risk of developing psychiatric disorders, as well as, a vulnerability to alcohol addiction in adulthood. Here, we examined the effects of combined ethanol exposure during late pregnancy and postnatal maternal separation (MS) on HPA responsiveness, anxiety behavior and preference for alcohol consumption in adult male rats. Animals exposed to both conditions revealed a decrease in blood levels of allopregnanolone accompanied by increased anxiety behavior...
December 6, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29223173/the-worried-well-characteristics-of-cognitively-normal-patients-presenting-to-a-rural-and-remote-memory-clinic
#4
Ryan Verity, Andrew Kirk, Megan E O'Connell, Chandima Karunanayake, Debra G Morgan
INTRODUCTION: In an effort to better understand why cognitively normal patients were referred to a memory clinic, we sought to identify features of "worried well" patients to better identify those more likely to be cognitively normal. METHODS: In total, 375 consecutive patients referred by primary care practitioners to a Rural and Remote Memory Clinic were categorized into two groups based on their neurologic diagnosis, "worried well" (cognitively normal, N=81) or "other" (patients with any neurologic diagnosis, N=294)...
December 10, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29222991/salivary-immune-proteins-monitoring-can-help-detection-of-binge-and-chronic-alcohol-drinkers-preliminary-findings
#5
Napoleon Waszkiewicz, Beata Galińska-Skok, Anna Zalewska, Sławomir Dariusz Szajda, Krzysztof Zwierz, Magdalena Więdłocha, Agata Szulc
BACKGROUND: We compared effects of binge and chronic alcohol drinking on oral health and salivary immunity proteins. METHODS: The study involved males: 13 healthy social-drinking (C), 10 alcohol-dependent after chronic alcohol-intoxication (A), and 8 binge-drinkers after a single binge-drinking session (B). We compared periodontal/dental state and salivary immune proteins (lactoferrin -Lf, lysozyme -Lz, oral peroxidase -OPO, immunoglobulin A -IgA) in all groups...
December 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29222923/co-administration-of-low-dose-naltrexone-and-bupropion-reduces-alcohol-drinking-in-alcohol-preferring-p-rats
#6
Emily R Nicholson, Julian E Dilley, Janice C Froehlich
BACKGROUND: This study examined whether combining naltrexone (NTX) with bupropion (BUP) is more effective in reducing alcohol drinking in alcohol-preferring (P) rats with a genetic predisposition toward high voluntary alcohol intake than is either drug alone. METHODS: Alcohol-experienced, adult, male, alcohol-preferring (P) rats were fed NTX alone in a dose of 10.0 mg/kg BW, BUP alone in a dose of 10.0 mg/kg BW, BUP alone in a dose of 20.0 mg/kg BW, NTX (10.0 mg/kg BW) + BUP (10...
December 9, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29222910/associations-between-maoa-uvntr-genotype-maltreatment-maoa-methylation-and-alcohol-consumption-in-young-adult-males
#7
Megha Bendre, Erika Comasco, Dave Checknita, Jari Tiihonen, Sheilagh Hodgins, Kent W Nilsson
BACKGROUND: Epigenetic mechanisms are candidate moderators of the effect of maltreatment on brain and behavior. Interactions between maltreatment and the Monoamine Oxidase A upstream variable number tandem repeat genotype (MAOA-uVNTR) are associated with alcohol-related problems. However, presently it is not known whether DNA methylation moderates this association. The study focused on fifty-three young adult males and aimed to determine: whether MAOA methylation moderated the association of alcohol-related problems with the interaction of MAOA-uVNTR and maltreatment; and whether alcohol consumption moderated the association of MAOA methylation with the interaction of MAOA-uVNTR and maltreatment...
December 9, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29222878/non-communicable-diseases-food-and-nutrition-in-vietnam-from-1975-to-2015-the-burden-and-national-response
#8
Tuan T Nguyen, Minh V Hoang
BACKGROUND AND OBJECTIVES: This review manuscript examines the burden and national response to non-communicable diseases (NCDs), food and nutrition security in Vietnam from 1975 to 2015. METHODS AND STUDY DESIGN: We extracted data from peer-reviewed manuscripts and reports of nationally representative surveys and related policies in Vietnam. RESULTS: In 2010, NCDs accounted for 318,000 deaths (72% of total deaths), 6.7 million years of life lost, and 14 million disability-adjusted life years in Vietnam...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29222577/occupational-prestige-trajectory-and-the-risk-of-lung-and-head-and-neck-cancer-among-men-and-women-in-france
#9
Gwenn Menvielle, Julien Dugas, Jeanna-Eve Franck, Matthieu Carton, Brigitte Trétarre, Isabelle Stücker, Danièle Luce
OBJECTIVES: This study aimed at investigating the associations between occupational prestige trajectories and lung and head and neck (HN) cancer risk and to assess to what extent smoking, alcohol drinking, and occupational exposures contribute to these associations. METHODS: Using data from the ICARE case-control study (controls (2676 men/715 women), lung cancers (2019 men/558 women), HN cancers (1793 men/305 women), we defined occupational prestige trajectories using group-based modeling of longitudinal data...
December 9, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/29222479/gdf15-deficiency-exacerbates-chronic-alcohol-and-carbon-tetrachloride-induced-liver-injury
#10
Hyo Kyun Chung, Jung Tae Kim, Hyeon-Woo Kim, Minjoo Kwon, So Yeon Kim, Minho Shong, Koon Soon Kim, Hyon-Seung Yi
Growth differentiation factor 15 (GDF15) has recently been shown to have an important role in the regulation of mitochondrial function and in the pathogenesis of complex human diseases. Nevertheless, the role of GDF15 in alcohol-induced or fibrotic liver diseases has yet to be determined. In this study, we demonstrate that alcohol- or carbon tetrachloride (CCl4)-mediated hepatic GDF15 production ameliorates liver inflammation and fibrosis. Alcohol directly enhanced GDF15 expression in primary hepatocytes, which led to increased oxygen consumption...
December 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29221432/sex-and-ethnic-racial-specific-risk-factors-for-gallbladder-disease
#11
Jane C Figueiredo, Christopher Haiman, Jacqueline Porcel, James Buxbaum, Daniel Stram, Neal Tambe, Wendy Cozen, Lynne Wilkens, Loic Le Marchand, Veronica Wendy Setiawan
BACKGROUND: Gallbladder disease (GBD) is a highly prevalent condition; however, little is known about potential differences in risk factors by sex and ethnicity/race. Our aim was to evaluate dietary, reproductive and obesity-related factors and GBD in multiethnic populations. METHODS: We performed a prospective analysis from the Multiethnic Cohort study who self-identified as non-Hispanic White (n = 32,103), African American (n = 30,209), Japanese (n = 35,987), Native Hawaiian (n = 6942) and Latino (n = 39,168)...
December 8, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/29220643/polygenic-risk-for-alcohol-consumption-and-its-association-with-alcohol-related-phenotypes-do-stress-and-life-satisfaction-moderate-these-relationships
#12
Gabry W Mies, Karin J H Verweij, Jorien L Treur, Lannie Ligthart, Iryna O Fedko, Jouke Jan Hottenga, Gonneke Willemsen, Meike Bartels, Dorret I Boomsma, Jacqueline M Vink
BACKGROUND: Genetic and environmental factors contribute about equally to alcohol-related phenotypes in adulthood. In the present study, we examined whether more stress at home or low satisfaction with life might be associated with heavier drinking or more alcohol-related problems in individuals with a high genetic susceptibility to alcohol use. METHODS: Information on polygenic scores and drinking behavior was available in 6705 adults (65% female; 18-83 years) registered with the Netherlands Twin Register...
December 2, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29220547/impact-of-moderate-alcohol-discontinuation-on-insulin-action-and-secretion-in-latinos-with-and-without-hepatitis-c
#13
Lindsay A Uribe, Peter Bacchetti, Nicholas Gelman, Esteban Burchard, Mark Fitch, Marc Hellerstein, Mandana Khalili
BACKGROUND/AIMS: Insulin resistance (IR) is associated with hepatitis C infection (HCV), and Latinos are both at risk for IR and are disproportionately affected by HCV. Moderate alcohol consumption improves insulin sensitivity and may modify HCV-associated IR. We investigated the impact of moderate alcohol discontinuation on insulin sensitivity and secretion in Latinos using direct measurements. METHODS: Twenty-five non-diabetic, non-cirrhotic Latino adults without (n=17) or with (n=8) HCV underwent 3-day metabolic assessment before and after prescription of 6 weeks of moderate alcohol discontinuation...
December 8, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29219783/diet-and-other-lifestyle-factors-associated-with-prostate-cancer-differ-between-the-german-and-italian-region-of-switzerland
#14
Aline Richard, David Faeh, Matthias Bopp, Sabine Rohrmann
PURPOSE: In Switzerland, prostate cancer mortality is higher in the German than in the Italian-speaking region. We aimed at exploring the association of living in one of the two regions with lifestyle factors presumably lowering the risk of prostate cancer. METHODS: We pooled data from the Swiss Health Survey, conducted every 5 years 1992 - 2012. Information on diet (meat, fish, dairy, fruits and vegetables), alcohol, smoking, physical activity and body mass index were dichotomized into "risky" and "risk-reducing" lifestyle behaviour with respect to prostate cancer...
December 8, 2017: International Journal for Vitamin and Nutrition Research. Journal International de Vitaminologie et de Nutrition
https://www.readbyqxmd.com/read/29217868/age-cohort-variation-in-drinking-among-people-with-physical-impairments-politically-oriented-coping-in-the-wake-of-the-great-recession
#15
Judith A Richman, Robyn Lewis Brown, Kathleen M Rospenda
People with physical impairments are at greater risk for economic hardship and more alcohol-related problems compared to the general population. We address age cohort differences in modes of coping with economic adversity and the extent to which modes of coping explain the relationships between age cohort membership and drinking outcomes among people with physical impairments. 176 respondents with physical impairments derived from a national sample completed a mail survey. Using SEM, we demonstrate that members of the Generation X age cohort manifest higher levels of alcohol consumption and problem-related drinking compared to baby boomers due to their lesser tendency to engage in politically-oriented coping to deal with economic adversity...
2017: Journal of Drug Issues
https://www.readbyqxmd.com/read/29217211/mediating-effects-of-cancer-risk-factors-on-the-association-between-race-and-cancer-incidence-analysis-of-the-nih-aarp-diet-and-health-study
#16
Tomi Akinyemiju, Justin Xavier Moore, Maria Pisu
PURPOSE: Racial disparities exist in the prevalence of cancer-related risk factors and incidence of cancer. The objective of this study is to determine if cancer-related risk factors mediate the association between race and cancer incidence. METHODS: We performed prospective analysis of data from the National Institutes of Health-American Association of Retired Persons Diet and Health Study, years 1995 through 2011. We compared differences in baseline characteristics between black and white participants using χ2 tests and Wilcoxon tests, as appropriate...
November 23, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/29217132/mobile-phone-sensors-and-supervised-machine-learning-to-identify-alcohol-use-events-in-young-adults-implications-for-just-in-time-adaptive-interventions
#17
Sangwon Bae, Tammy Chung, Denzil Ferreira, Anind K Dey, Brian Suffoletto
BACKGROUND: Real-time detection of drinking could improve timely delivery of interventions aimed at reducing alcohol consumption and alcohol-related injury, but existing detection methods are burdensome or impractical. OBJECTIVE: To evaluate whether phone sensor data and machine learning models are useful to detect alcohol use events, and to discuss implications of these results for just-in-time mobile interventions. METHODS: 38 non-treatment seeking young adult heavy drinkers downloaded AWARE app (which continuously collected mobile phone sensor data), and reported alcohol consumption (number of drinks, start/end time of prior day's drinking) for 28days...
November 27, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29216933/the-impact-of-victim-alcohol-consumption-and-perpetrator-use-of-force-on-perceptions-in-an-acquaintance-rape-vignette
#18
Amy L Brown, Jada Horton, Ariel Guillory
Research suggests that victims of incapacitated rape (when someone has sex with a person who is unable to consent to orresist sexual activity, usually because of intoxication) face higher levels of victim blame than do victims of forcible rape (Krahé, Temkin, & Bieneck, 2007). However, it is not clear whether blame is the result of victim alcohol consumption or the lack of force and resistance present during incapacitated rape; both of these factors have been shown to increase victim blame. The current vignette study crossed victim alcohol consumption and perpetrator use of force...
December 7, 2017: Violence and Victims
https://www.readbyqxmd.com/read/29214946/psychosomatic-and-psychosocial-questions-regarding-bariatric-surgery-what-do-we-know-or-what-do-we-think-we-know
#19
Stephan Herpertz, Henrik Kessler, Sebastian Jongen
SUBJECT: In view of the epidemic increase in severe obesity and the ineffectiveness of conservative weight-loss interventions, bariatric surgery delivers compelling results for patients with class II (BMI ≥ 35 kg/m²) and class III obesity (BMI ≥ 40 kg/m²), not only in reducing weight over the long term, but also in reducing obesity-related somatic comorbidity and improving psychosocial functioning and quality of life. Investigations into the psychosocial aspects of obesity surgery have proliferated over the last 15 years, providing a huge amount of essential research data...
December 2017: Zeitschrift Für Psychosomatische Medizin und Psychotherapie
https://www.readbyqxmd.com/read/29214654/role-of-the-innate-immune-system-in-the-neuropathological-consequences-induced-by-adolescent-binge-drinking
#20
REVIEW
María Pascual, Jorge Montesinos, Consuelo Guerri
Adolescence is a critical stage of brain maturation in which important plastic and dynamic processes take place in different brain regions, leading to development of the adult brain. Ethanol drinking in adolescence disrupts brain plasticity and causes structural and functional changes in immature brain areas (prefrontal cortex, limbic system) that result in cognitive and behavioral deficits. These changes, along with secretion of sexual and stress-related hormones in adolescence, may impact self-control, decision making, and risk-taking behaviors that contribute to anxiety and initiation of alcohol consumption...
December 7, 2017: Journal of Neuroscience Research
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