Read by QxMD icon Read


M Asunción Barreda-Manso, Natalia Yanguas-Casás, Manuel Nieto-Sampedro, Lorenzo Romero-Ramírez
Following a central nervous system (CNS) injury, restoration of the blood-brain barrier (BBB) integrity is essential for recovering homeostasis. When this process is delayed or impeded, blood substances and cells enter the CNS parenchyma, initiating an additional inflammatory process that extends the initial injury and causes so-called secondary neuronal loss. Astrocytes and profibrotic mesenchymal cells react to the injury and migrate to the lesion site, creating a new glia limitans that restores the BBB. This process is beneficial for the resolution of the inflammation, neuronal survival and the initiation of the healing process...
October 18, 2016: Journal of Cellular Physiology
Kacie Seil, Jennifer Marcum, Ramona Lall, Catherine Stayton
BACKGROUND: The New York City emergency department (ED) syndromic surveillance (SS) system provides near real-time data on the majority of ED visits. The utility of ED SS for injury surveillance has not been thoroughly evaluated. We created injury syndromes based on ED chief complaint information and evaluated their utility compared to administrative billing data. METHODS: Six injury syndromes were developed: traffic-related injuries to pedal cyclists, pedestrians, and motor vehicle occupants; fall-related injuries; firearm-related injuries; and assault-related stabbings...
December 2015: Injury Epidemiology
Mitsuharu Endo, Guljahan Ubulkasim, Chiho Kobayashi, Reiko Onishi, Atsu Aiba, Yasuhiro Minami
Ror2 receptor tyrosine kinase plays crucial roles in developmental morphogenesis and tissue-/organo-genesis. In the developing brain, Ror2 is expressed in neural stem/progenitor cells (NPCs) and involved in the regulation of their stemness. However, it remains largely unknown about its role in the adult brain. In this study, we show that Ror2 is up-regulated in reactive astrocytes in the neocortices within 3 days following stab-wound injury. Intriguingly, Ror2-expressing astrocytes were detected primarily at the area surrounding the injury site, where astrocytes express Nestin, a marker of NPCs, and proliferate in response to injury...
October 11, 2016: Glia
Simon Veldhoen, Andreas M Weng, Janine Knapp, Andreas S Kunz, Daniel Stäb, Clemens Wirth, Florian Segerer, Helge Hebestreit, Uwe Malzahn, Herbert Köstler, Thorsten A Bley
Purpose To assess the clinical feasibility of self-gated non-contrast-enhanced functional lung (SENCEFUL) magnetic resonance (MR) imaging for quantitative ventilation (QV) imaging in patients with cystic fibrosis (CF). Materials and Methods Twenty patients with CF and 20 matched healthy volunteers underwent functional 1.5-T lung MR imaging with the SENCEFUL imaging approach, in which a two-dimensional fast low-angle shot sequence is used with quasi-random sampling. The lungs were manually segmented on the ventilation-weighted images to obtain QV measurements, which were compared between groups...
October 6, 2016: Radiology
Azusa Kageyama, Shinji Sugiura
Caterpillar hairs are thought to act as a physical barrier against natural enemies, including parasitoids. However, very few studies have experimentally demonstrated how hairs protect caterpillars from parasitoid oviposition. To clarify the importance of caterpillar hairs as an anti-parasitoid defence, we observed the generalist endoparasitoid Meteorus pulchricornis (Hymenoptera: Braconidae) attacking both smooth and hairy caterpillars under laboratory conditions. A female Meteorus pulchricornis uses its ovipositor to inject venom and lay a single egg inside host larvae...
October 2016: Die Naturwissenschaften
Mazen J El Sayed, Hani Tamim, Aurelie Mailhac, N Clay Mann
BACKGROUND: Tourniquet use by Emergency Medical Services (EMS) can be life saving for severely injured patients. The adoption of this intervention is not well described in civilian settings. This study describes patterns and trends of tourniquet use by civilian EMS and identifies predictors of such use. METHODS: A retrospective study of four consecutive releases of the U.S. National Emergency Medical Services Information System (NEMSIS) public research dataset (2011-14) was conducted...
September 30, 2016: Prehospital Emergency Care
M Garetier, L Deloire, F Dédouit, E Dumousset, C Saccardy, D Ben Salem
Suicide is the eighth cause of mortality in France and the leading cause in people aged between 25 and 34 years. The most common methods of suicide are hanging, self-poisoning with medicines and firearms. Postmortem computed tomography (CT) is a useful adjunct to autopsy to confirm suicide and exclude other causes of death. At autopsy, fractures of the hyoid bone or thyroid cartilage, or both, are found in more than 50% of suicidal hangings. Cervical vertebra fractures are rare and only seen in suicide victims jumping from a great height...
September 26, 2016: Diagnostic and Interventional Imaging
Takaki Emura, Hiroshi Ohta, Noboru Oyachi, Takeyuki Suzuki
INTRODUCTION: Laparoscopic percutaneous extraperitoneal closure (LPEC) in boys is more complex than in girls, because the vas deferens and testicular vessels must be separated from the peritoneum. We therefore developed a needle-shaped surgical instrument that enables blunt separation. Here, we report the effectiveness of this new device. SURGICAL TECHNIQUE: The new device is a ligature carrier consisting of (1) an inner tube (19-G blunt needle) through which slides a rod with a loop wire at its tip that can catch and release suture materials and (2) an outer tube (17-G needle) with a cutting edge...
September 28, 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
M J Ramdass, P Harnarayan
INTRODUCTION Trinidad and Tobago is a trans-shipment point for the illegal trade of drugs, arms and ammunition and, as such, has a high incidence of gang-related warfare and drug-related crimes. This has led to a high incidence of gunshot and stab wounds, with associated major vascular injuries. We describe our management strategies learned from a decade of vascular trauma experience. METHODS A retrospective analysis of age, gender, type of trauma, vessel injured, procedure and outcome for all cases of vascular trauma between 2006 and 2015 at two surgical units in Trinidad and Tobago...
September 23, 2016: Annals of the Royal College of Surgeons of England
B Shazi, J L Bruce, G L Laing, B Sartorius, D L Clarke
INTRODUCTION The purpose of this study was to audit our current management of colonic trauma, and to review our experience of colonic trauma in patients who underwent initial damage control (DC) surgery. METHODS All patients treated for colonic trauma between January 2012 and December 2014 by the Pietermaritzburg Metropolitan Trauma Service were included in the study. Data reviewed included mechanism of injury, method of management (primary repair [PR], primary diversion [PD] or DC) and outcome (complications and mortality rate)...
September 23, 2016: Annals of the Royal College of Surgeons of England
Ousmane Thiam, Ibrahima Konate, Mohamadou Lamine Gueye, Alpha Omar Toure, Mamadou Seck, Mamadou Cisse, Balla Diop, Elias Said Dirie, Ousmane Ka, Mbaye Thiam, Madieng Dieng, Abdarahmane Dia, Cheikh Tidiane Toure
INTRODUCTION: Diaphragmatic injuries include wounds and diaphragm ruptures, due to a thoracoabdominal blunt or penetrating traumas. Their incidence ranges between 0.8 and 15 %. The diagnosis is often delayed, despite several medical imaging techniques. The surgical management remains controversal, particularly for the choice of the surgical approach and technique. The mortality is mainly related to associated injuries. The aim of our study was to evaluate the incidence of diaphragmatic injuries occuring in thoraco-abdominal traumas, and to discuss their epidemiology, diagnosis and treatment...
2016: SpringerPlus
Fahad Almehmadi, Mark Chandy, Kim A Connelly, Jeremy Edwards
Delayed cardiac tamponade after a penetrating chest injury is a rare complication. The clinical diagnosis of tamponade is facilitated with imaging. We present a case report of a 23-year-old male who was brought to emergency after multiple stab wounds to the chest. After resuscitation and repair of laceration of right internal mammary artery and right ventricle, he was discharged but later returned with shortness of breath. Echocardiography revealed a rare case of delayed pericardial tamponade causing left ventricular collapse...
2016: Case Reports in Cardiology
Shogo Ogita, Toshiki Endo, Tomoo Inoue, Kenichi Sato, Hidenori Endo, Teiji Tominaga
BACKGROUND: In the literature, perimedullary arteriovenous fistula (AVF) is an uncommon spinal vascular malformation that is generally regarded as a congenital lesion. To our knowledge, only a few cases of traumatic perimedullary AVF have been reported in the literature so far. CASE DESCRIPTION: A 58-year-old man presented with subarachnoid hemorrhage (SAH) resulting from a secondary perimedullary arteriovenous fistula (AVF) induced by a glass stab injury to his right posterior neck...
September 16, 2016: World Neurosurgery
André Luis Ribeiro Ribeiro, Luciana Campêlo da Silva Gillet, Hiam Ghassan de Vasconcelos, Luciana de Castro Rodrigues, João de Jesus Viana Pinheiro, Sérgio de Melo Alves-Junior
PURPOSE: Facial fractures are an important health problem worldwide that can cause temporary or permanent disability and an economic burden. Identifying the risk factors associated with facial fractures is a valuable tool to create preventive public health strategies. This study evaluated the epidemiologic profile of facial fractures in northern Brazil. PATIENTS AND METHODS: Medical records of 1,969 patients who sustained facial fractures were analyzed for characteristics of the population, types of facial fractures, and treatment performed...
August 25, 2016: Journal of Oral and Maxillofacial Surgery
Monica S Wu, Eric A Storch
Harm-related, or "aggressive," obsessions are a symptom subtype in obsessive-compulsive disorder (OCD). Given the violent nature of these thoughts, the stark contrast between the child's character and the content of these obsessions often results in high levels of distress for not only the patient but also the family. This case report illustrates the application of family-based exposure and response prevention (ERP) for a 15-year-old male presenting with harm-related obsessions and mild depressive symptoms secondary to the OCD...
November 2016: Journal of Clinical Psychology
J Hollander, M C van der Molen, P R Fa Si Oen, A J Duits, D R Nellensteijn
Background: Trauma registry plays an important role in a process of health-service improvement. Organization of trauma care in the Caribbean is limited; there is lack of registry and distribution of patients. Objective: This was to compare incidence-trends of patients with trauma-related injury to the Dutch trauma registry for 14 years, since Curacao is part of the Dutch Caribbean. Methods: Data of all injured patients admitted to Emergency Department (ED) from January 1, 2000 to December 31, 2013, were retrospectively analysed using a prospective trauma registry...
March 11, 2016: West Indian Medical Journal
Anna Ghizzani, Piersante Sestini
BACKGROUND: Sexual pain is frequently seen in gynecological practice as a consequence of lower tract pathology. When organic causes are ruled out we must think of a functional pain syndrome such as the genital pelvic pain/penetration disorder (GPPD) whose diagnostic criteria are defined by the Diagnostic and Statistic Manual-5; these criteria describe both vaginismus and vulvodynia that present themselves with somewhat different clinical dimensions and require different treatments. Even if gynecologists do not usually manage functional sexual pain, they can easily reach the differential diagnosis through the sexual pain anamnesis because some symptoms are specific of one or the other condition...
September 8, 2016: Minerva Ginecologica
Pavlos Pavlidis, Maria-Valeria Karakasi, Theodossios A Birbilis
Penetrating head injuries due to the use of screwdrivers as wounding agents in acts of interpersonal violence seldom occur. The aim of this article is to update and summarize the relevant literature on penetrating craniocerebral screwdriver stab wounds and to report a new case of screwdriver assault. A number of studies were reviewed to investigate the incidence, distribution, common findings, mechanism of injury, differential diagnostic criteria, complications, treatment, and prognosis of craniocerebral screwdriver stab injuries...
August 26, 2016: American Journal of Forensic Medicine and Pathology
Christine M Van Dillen, Matthew R Tice, Archita D Patel, David A Meurer, Joseph A Tyndall, Marie Carmelle Elie, Jonathan J Shuster
Introduction. Limited evidence is available on simulation training of prehospital care providers, specifically the use of tourniquets and needle decompression. This study focused on whether the confidence level of prehospital personnel performing these skills improved through simulation training. Methods. Prehospital personnel from Alachua County Fire Rescue were enrolled in the study over a 2- to 3-week period based on their availability. Two scenarios were presented to them: a motorcycle crash resulting in a leg amputation requiring a tourniquet and an intoxicated patient with a stab wound, who experienced tension pneumothorax requiring needle decompression...
2016: Emergency Medicine International
Stella R Smith, Katy Newton, Jennifer A Smith, Jo C Dumville, Zipporah Iheozor-Ejiofor, Lyndsay E Pearce, Paul J Barrow, Laura Hancock, James Hill
BACKGROUND: A perianal abscess is a collection of pus under the skin, around the anus. It usually occurs due to an infection of an anal gland. In the UK, the annual incidence is 40 per 100,000 of the adult population, and the standard treatment is admission to hospital for incision and drainage under general anaesthetic. Following drainage of the pus, an internal dressing (pack) is placed into the cavity to stop bleeding. Common practice is for community nursing teams to change the pack regularly until the cavity heals...
2016: Cochrane Database of Systematic Reviews
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"