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https://www.readbyqxmd.com/read/29445372/robust-phenotypic-activation-of-eosinophils-during-experimental-toxocara-canis-infection
#1
Joice Margareth de Almeida Rodolpho, Luciana Camillo, Márcio Sobreira Silva Araújo, Elaine Speziali, Jordana Grazziela Coelho-Dos-Reis, Ricardo de Oliveira Correia, Débora Meira Neris, Olindo Assis Martins-Filho, Andréa Teixeira-Carvalho, Fernanda de Freitas Anibal
Eosinophils are multifunctional cells that have cytotoxic proinflammatory activities and stimulate CD4 + T-cells in experimental models of allergy and parasitic infections. Eosinophils, when exposed to antigens, are activated, expressing the CD38/CD69 molecules and exhibited increased expression of major histocompatibility complex (MHC-II), CD80 and CD86, suggesting they play a role upon Toxocara canis antigen stimulation. In the present study, we evaluated the profile of eosinophils using conventional and image flow cytometry upon experimental T...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29440049/withdrawn-cutaneous-larva-migrans-with-pulmonaryinvolvement
#2
(no author information available yet)
No abstract text is available yet for this article.
February 12, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29436018/subacute-cutaneous-lupus-erythematosus-presenting-in-twins
#3
Michael A Montuno, Ann A Church, Jennifer J Schoch, Israel D Andrews
Subacute cutaneous lupus erythematosus is a clinically distinct form of cutaneous lupus erythematosus, with age of onset typically in the second to fifth decades. Eleven cases have been reported in childhood, and we present the first known case of subacute cutaneous lupus erythematosus in identical twins. Although flares are typically photo-induced, we present an annular eruption typical of subacute cutaneous lupus erythematosus with concurrent pinworm infestation, with recurrence of disease with cutaneous larva migrans...
February 13, 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29420245/imported-gnathostomiasis-manifesting-as-cutaneous-larva-migrans-and-l%C3%A3-ffler-s-syndrome
#4
William L Hamilton, Daniel Agranoff
Here, we report an unusual case of invasive gnathostomiasis in a returning traveller, with a shifting pattern of relapsing cutaneous disease. The previously fit and well 32-year-old man first presented with serpiginous, pruriginous erythematous tracks characteristic of cutaneous larva migrans shortly after returning from South-East Asia. He was systemically well with no other symptoms. After ivermectin therapy, he re-presented with respiratory symptoms, peripheral eosinophilia and transient pulmonary infiltrates; the classic triad of Löffler's syndrome associated with invasive helminth infection...
February 2, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29417800/cutaneous-larva-migrans-and-tungiasis-infestations-of-the-affluent-society
#5
Stefano Veraldi, Gianluca Nazzaro
No abstract text is available yet for this article.
February 7, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29402399/tick-borne-illness-lyme-disease
#6
REVIEW
Larry M Bush, Maria T Vazquez-Pertejo
Lyme disease is the most commonly reported tick-borneillness in the United States. Thecausative spirochete, Borrelia burgdorferi is transmitted by 4 species of Ixodes tick species. Over 90% of US cases occur in northeasternstates from Maine to Virginia, and in Wisconsin, Minnesota, and Michigan. Infection also takes place in northern California and Oregon. Lyme borreliosis is also diagnosed in parts of Europe, China, and Japan. The white-footed mouse is the primary animal reservoir for B. burgdorferi in the U...
February 2, 2018: Disease-a-month: DM
https://www.readbyqxmd.com/read/29398300/-massive-infestation-with-larva-migrans
#7
Tiara Souza Magalhães, Marcello Menta Simonsen Nico
No abstract text is available yet for this article.
February 2, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29394366/amblyomma-americanum-acari-ixodidae-ticks-are-not-vectors-of-the-lyme-disease-agent-borrelia-burgdorferi-spirocheatales-spirochaetaceae-a-review-of-the-evidence
#8
Ellen Y Stromdahl, Robyn M Nadolny, Graham J Hickling, Sarah A Hamer, Nicholas H Ogden, Cory Casal, Garrett A Heck, Jennifer A Gibbons, Taylor F Cremeans, Mark A Pilgard
In the early 1980s, Ixodes spp. ticks were implicated as the key North American vectors of Borrelia burgdorferi (Johnson, Schmid, Hyde, Steigerwalt and Brenner) (Spirocheatales: Spirochaetaceae), the etiological agent of Lyme disease. Concurrently, other human-biting tick species were investigated as potential B. burgdorferi vectors. Rashes thought to be erythema migrans were observed in patients bitten by Amblyomma americanum (L.) (Acari: Ixodidae) ticks, and spirochetes were visualized in a small percentage of A...
January 31, 2018: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29386499/-a-case-of-lyme-neuroborreliosis-without-erythema-migrans
#9
Katsuki Eguchi, Kazuhumi Tsuzaka, Ichiro Yabe, Hidenao Sasaki
A 56-year-old man was sustained ticks at the left axilla and flank. He did not have a rash. About 3 months after the tick bites, he developed back pain, right leg weakness, right abducens nerve palsy, and left facial palsy. Western blot analysis for serum IgM and IgG antibodies against Borrelia were positive. We diagnosed Lyme borreliosis. The patient was treated with antibiotics and steroids, and the symptoms improved. Our findings demonstrate that, even if erythema migrans is not obvious, neuroborreliosis should be considered when neurological signs, such as multiple cranial nerve palsies, are present...
January 31, 2018: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/29385444/oral-doxycycline-versus-intravenous-ceftriaxone-for-treatment-of-multiple-erythema-migrans-an-open-label-alternate-treatment-observational-trial
#10
Daša Stupica, Maša Velušcek, Rok Blagus, Petra Bogovic, Tereza Rojko, Tjaša Cerar, Franc Strle
Background: Several guidelines advocate the same treatment approaches for both early disseminated Lyme borreliosis, manifested as multiple erythema migrans (EM), and early localized Lyme borreliosis, manifested as solitary EM. Methods: Oral doxycycline (100 mg q12h) was compared on a non-inferiority premise with intravenous ceftriaxone (2 g q24h) for 14 days in 200 adult European patients with multiple EM in an open-label alternate-treatment observational trial performed in a single-centre university hospital...
January 29, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29377078/impact-of-climate-change-on-dermatological-conditions-related-to-flooding-update-from-the-international-society-of-dermatology-climate-change-committee
#11
REVIEW
Johannes F Dayrit, Lunardi Bintanjoyo, Louise K Andersen, Mark Dennis P Davis
Climate change contributes to the increase in severity and frequency of flooding, which is the most frequent and deadly disaster worldwide. Flood-related damage can be very severe and include health effects. Among those health impacts, dermatological diseases are one of the most frequently encountered. Both infectious and noninfectious dermatological conditions are increasing after flooding. We searched PubMed using the search term climate change OR global warming OR rainfall OR flooding OR skin. Articles published in the English-language literature were included...
January 29, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29373923/a-unique-case-of-cutaneous-larva-migrans-acquired-within-the-province-of-quebec-and-successfully-treated-with-topical-ivermectin
#12
Anne-Sophie Smilga, Janie Bujold
Cutaneous larva migrans (CLM) is a zoonotic helminthiasis frequently imported to Canada by travellers to beach destinations in the tropics. The preferred treatment is oral ivermectin. We present a case of CLM acquired within the province of Quebec, a first in our provincial health records. Our case also puts forward the use of topical ivermectin as a possibly effective CLM treatment approach as our patient was successfully treated with 1 month of an ivermectin 1% cream applied locally twice daily.
January 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29368841/multiple-erythema-migrans-due-to-borreliosis
#13
Nicola DI Meo, Chiara Retrosi, Paola Corneli, Giusto Trevisan
No abstract text is available yet for this article.
January 24, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29351071/a-frequent-roundworm-baylisascaris-transfuga-in-overpopulated-brown-bears-ursus-arctos-in-slovakia-a-problem-worthy-of-attention
#14
Gabriela Štrkolcová, Mária Goldová, Viliam Šnábel, Marta Špakulová, Tatiana Orosová, Miloš Halán, Jana Mojžišová
The genus Baylisascaris (order Ascaridida) includes numerous relatively host-specific nematodes, which are common in intestines of wild mammals. Some of them may have impact on veterinary and public health, as their larvae have the potential to cause visceral, ocular, and/or neural larva migrans in a wide range of mammals, birds, and humans. Baylisascaris transfuga is a parasite occurring in a range of bear species throughout the world. We present the current data on B. transfuga occurrence in brown bears from a relatively restricted territory of the Poľana Protected Landscape Area in Central Slovakia, obtained by traditional methods (faecal examination, morphology)...
March 26, 2018: Acta Parasitologica
https://www.readbyqxmd.com/read/29344989/salmon-calcitonin-ameliorates-migraine-pain-through-modulation-of-cgrp-release-and-dural-mast-cell-degranulation-in-rats
#15
Erkan Kilinc, Yasar Dagistan, Aysel Kukner, Bayram Yilmaz, Sami Agus, Gizem Soyler, Fatma Tore
The exact mechanism of migraine pathophysiology still remains unclear due to the complex nature of migraine pain. Salmon calcitonin (SC) exhibits antinociceptive effects in the treatment of various pain conditions. In this study, we explored the mechanisms underlying the analgesic effect of salmon calcitonin on migrane pain using glyceryltrinitrate(GTN)-induced model of migraine and ex-vivo meningeal preparations in rats. Rats were administered intraperitoneally saline, GTN(10mg/kg), vehicle, saline+GTN, SC(50μg/kg)+GTN, and SC alone...
January 18, 2018: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/29335689/psoriasis-a-review-of-systemic-comorbidities-and-dental-management-considerations
#16
John K Brooks
OBJECTIVE: There is a growing body of evidence to substantiate that cutaneous psoriasis is associated with an increased risk for a multitude of systemic disorders. Although there is an extensive array of medical publications regarding psoriasis, the dental literature has almost exclusively been focused on erythema migrans and occasionally, with oral psoriatic mucositis, chronic periodontitis, and psoriatic arthritis of the temporomandibular joint. This report will review the diversity of systemic comorbidities, namely cardiovascular, neurologic, renal, liver, gastrointestinal, pulmonary, endocrine, ocular, arthritic (including temporomandibular joint), nail, cutaneous, and psychologic (including suicide) disorders; neoplasia; infection; dyslipidemia; vitamin D deficiency; substance abuse; higher mortality; and oral mucosal involvement...
2018: Quintessence International
https://www.readbyqxmd.com/read/29330280/cutaneous-larva-migrans-with-pulmonary-involvement
#17
Douglas Maslin, Marc Wallace
No abstract text is available yet for this article.
January 12, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29299379/headache-in-the-first-manifestation-of-multiple-sclerosis%C3%A2-%C3%A2-prospective-multicenter-study
#18
Marcel Gebhardt, Peter Kropp, Tim P Jürgens, Frank Hoffmann, Uwe K Zettl
Objectives: Multiple sclerosis (MS) is the most frequent immune-mediated inflammation of the central nervous system that can lead to early disability. Headaches have not been considered as MS-related symptoms initially, whereas higher prevalence rates were reported since 2000. Postmortem histological analyses of MS patients' brains revealed lymphoid follicle-like structures in the cerebral meninges which suggest a possible pathophysiological explanation for the high headache prevalence in MS...
December 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29275956/lyme-carditis-early-occurrence-and-prolonged-recovery
#19
Jianwei Fu Md, Luna Bhatta
Lyme carditis is an uncommon manifestation of early disseminated Lyme disease. This case illustrates a 66-year-old male with complaints of fatigue, myalgias, and fever after a tick bite 3days earlier. A large erythema migrans was found on the chest wall. Initial electrocardiogram showed sinus rhythm with second degree 2:1 atrioventricular (AV) block, which progressed to intermittent complete AV block rapidly. He was treated with intravenous ceftriaxone. Over the course of 2-weeks of antibiotic therapy, the intermittent high-grade AV block improved slowly and progressively...
December 14, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29260744/-clinical-presentation-of-ixodes-tick-borne-borreliosis-caused-by-borrelia-miyamotoi-in-the-context-of-an-immune-response-to-the-pathogen
#20
A E Platonov, M G Toporkova, N M Kolyasnikova, O A Stukolova, A S Dolgova, A V Brodovikova, N A Makhneva, L S Karan, J Koetsveld, G A Shipulin, V V Maleev
Ixodes tick-borne borreliosis caused by Borrelia miyamotoi (ITBB-BM) is a previously unknown infectious disease discovered in Russia. AIM: The present study continues the investigation of the clinical features of ITBB-BM in the context of an immune system-pathogen interaction. SUBJECTS AND METHODS: The study enrolled 117 patients with ITBB-BM and a comparison group of 71 patients with Lyme disease (LD) that is ITBB with erythema migrans. All the patients were treated at the New Hospital, Yekateringburg...
2017: Terapevticheskiĭ Arkhiv
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