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https://www.readbyqxmd.com/read/29664394/dynamics-of-spirochetemia-and-early-pcr-detection-of-borrelia-miyamotoi
#1
Lyudmila Karan, Marat Makenov, Nadezhda Kolyasnikova, Olga Stukolova, Marina Toporkova, Olga Olenkova
We investigated whether Borrelia miyamotoi disease can be detected in its early stage by using PCR for borrelial 16S rRNA, which molecule (DNA or RNA) is the best choice for this test, and whether spirochetes are present in blood during the acute phase of B. miyamotoi disease. A total of 473 patients with a suspected tickborne infection in Yekaterinburg, Russia, in 2009, 2010, and 2015 were enrolled in this study. Blood samples were analyzed by using quantitative PCR or ELISA, and a diagnosis of borreliosis was confirmed for 310 patients...
May 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29644775/exploring-the-combination-of-sski-and-topical-heparin-in-a-case-of-erythema-nodosum-migrans
#2
Manu Sehrawat, Niharika Dixit, Kabir Sardana, Purnima Malhotra
Erythema nodosum migrans (subacute nodular migratory panniculitis) is an uncommon type of panniculitis characterized by migrating subcutaneous nodules or plaque on the lower extremity. There are a very few cases of Erythema nodosum migrans reported and thus its appropriate treatment modality is not defined. We describe a case of a 30-year-old male with idiopathic erythema nodosum migrans which was manifest centrifugally spreading, slightly morpheaform erythematous plaque on the lower left leg. The patient was diagnosed initially and treated as a case of furunculosis with poor clinical response...
April 11, 2018: Dermatologic Therapy
https://www.readbyqxmd.com/read/29600691/a-giant-annular-rash-in-a-tuscanian-woodman-the-many-faces-of-erythema-chronicum-migrans
#3
Bruno Gualtieri, Roberto Maglie, Annalisa Tonini, Salvatore Panduri, Andrea Chiricozzi, Marco Romanelli
No abstract text is available yet for this article.
March 29, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29600690/occurrence-of-lyme-disease-infection-in-a-non-endemic-area-in-northern-italy
#4
Sara G Rimoldi, Stefania Merli, Giovanna Bestetti, Vania Giacomet, Giuliana Cislaghi, Romualdo Grande, Sergio Sanzani, Cristina Pagani, Giusto Trevisan, Eleonora DE Faveri, Maria R Gismondo, Eva Ruzić-Sabljić
BACKGROUND: In Italy, the incidence of human tick borne disease has increased over the last decades. Since 2015 a multidisciplinary group has been established in Sacco Hospital for the management of the patients affected by Lyme Disease (LD). A retrospective evaluation (2015-2017) was performed for LD in non-endemic areas. METHODS: Retrospective analysis of all 1000 samples for 800 patients screened for LD antibodies at the Sacco Hospital in 3 years (2015-2017)...
March 29, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29600131/tick-bite-erythema-migrans
#5
Yoshinosuke Shimamura, Takuto Maeda, Yufu Gocho
This manuscript describes the typical presentation of erythema migrans caused by tick bite. The purposes of this article are (i) to encourage physicians to observe patients with tick bite carefully since it may cause fatal encephalitis, and (ii) to facilitate physicians, especially in endemic areas, to consider tick-borne encephalitis virus as one of the causes of encephalitis.
March 2018: Journal of General and Family Medicine
https://www.readbyqxmd.com/read/29588280/clinical-presentation-of-lyme-disease-in-the-higher-risk-region-of-quebec-a-retrospective-descriptive-study
#6
Audrey Charbonneau, Louis-Philippe Charette, Geneviève Rouleau, Mélissa Savary, Alexandra Wilson, Emily Heer, Karine Bériault, Alexandra de Pokomandy
BACKGROUND: Lyme disease is emerging in Canada. This study aimed to describe the use of serologic testing for the disease in the La Pommeraie health region in southern Quebec between 2012 and 2015 and to describe the clinical presentation of laboratory-confirmed cases. METHODS: The medical charts of all patients investigated for Lyme disease at the Brome-Missisquoi-Perkins Hospital's laboratory between 2012 and 2015 were reviewed for results of serologic testing...
March 23, 2018: CMAJ Open
https://www.readbyqxmd.com/read/29505880/comparison-of-phenoxymethylpenicillin-amoxicillin-and-doxycycline-for-erythema-migrans-in-general-practice-a-randomised-controlled-trial-with-a-one-year-follow-up
#7
Knut Eirik Eliassen, Harald Reiso, Dag Berild, Morten Lindbæk
OBJECTIVES: Comparison of the three most commonly used antibiotics for erythema migrans (EM) in Norwegian primary care. METHODS: A randomised, parallel, controlled trial. Treatments were open to the patients, but blinded for the GPs and investigators. Patients aged ≥18 years, clinically diagnosed with EM were eligible for inclusion. Block randomisation was processed in blocks of six. Patients were assigned to receive one of three antibiotic treatments for 14 days: phenoxymethylpenicillin (PCV), amoxicillin, or doxycycline...
March 2, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29477274/is-the-risk-of-early-neurologic-lyme-borreliosis-reduced-by-preferentially-treating-patients-with-erythema-migrans-with-doxycycline
#8
Franc Strle, Daša Stupica, Petra Bogovič, Paul Visintainer, Gary P Wormser
Doxycycline is highly effective treatment for early neurologic Lyme borreliosis (NLB). Nineteen studies were reviewed to determine if treatment of patients with erythema migrans with other oral antibiotics would increase the risk for developing NLB. In the eight studies that directly compared doxycycline to another antibiotic, the pooled difference indicated a 0.2% greater risk of developing NLB in doxycycline-treated patients (95% CI: -1.0%, +1.4%; P = 0.77), with an estimated heterogeneity of 0.0%, P = 0...
February 2, 2018: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/29458421/epidemiology-of-canine-gastrointestinal-helminths-in-sub-saharan-africa
#9
Nozyechi Ngulube Chidumayo
BACKGROUND: Dogs have a close association with humans providing companionship, security and a source of dietary protein. However, dogs are also potential carriers of zoonotic pathogens. Dogs, therefore, pose a public health risk and a good understanding of canine diseases is important for planning and implementing control measures. The aim of this study was to characterise canine helminthiasis in sub-Saharan Africa using a systematic approach. METHODS: Pubmed and Google Scholar were searched for relevant primary studies published from 2000...
February 20, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29445372/robust-phenotypic-activation-of-eosinophils-during-experimental-toxocara-canis-infection
#10
Joice Margareth de Almeida Rodolpho, Luciana Camillo, Márcio Sobreira Silva Araújo, Elaine Speziali, Jordana Grazziela Coelho-Dos-Reis, Ricardo de Oliveira Correia, Débora Meira Neris, Olindo Assis Martins-Filho, Andréa Teixeira-Carvalho, Fernanda de Freitas Anibal
Eosinophils are multifunctional cells that have cytotoxic proinflammatory activities and stimulate CD4 + T-cells in experimental models of allergy and parasitic infections. Eosinophils, when exposed to antigens, are activated, expressing the CD38/CD69 molecules and exhibited increased expression of major histocompatibility complex (MHC-II), CD80 and CD86, suggesting they play a role upon Toxocara canis antigen stimulation. In the present study, we evaluated the profile of eosinophils using conventional and image flow cytometry upon experimental T...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29440049/withdrawn-cutaneous-larva-migrans-with-pulmonaryinvolvement
#11
(no author information available yet)
No abstract text is available yet for this article.
February 12, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29436018/subacute-cutaneous-lupus-erythematosus-presenting-in-twins
#12
Michael A Montuno, Ann A Church, Jennifer J Schoch, Israel D Andrews
Subacute cutaneous lupus erythematosus is a clinically distinct form of cutaneous lupus erythematosus, with age of onset typically in the second to fifth decades. Eleven cases have been reported in childhood, and we present the first known case of subacute cutaneous lupus erythematosus in identical twins. Although flares are typically photo-induced, we present an annular eruption typical of subacute cutaneous lupus erythematosus with concurrent pinworm infestation, with recurrence of disease with cutaneous larva migrans...
February 13, 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29420245/imported-gnathostomiasis-manifesting-as-cutaneous-larva-migrans-and-l%C3%A3-ffler-s-syndrome
#13
William L Hamilton, Daniel Agranoff
Here, we report an unusual case of invasive gnathostomiasis in a returning traveller, with a shifting pattern of relapsing cutaneous disease. The previously fit and well 32-year-old man first presented with serpiginous, pruriginous erythematous tracks characteristic of cutaneous larva migrans shortly after returning from South-East Asia. He was systemically well with no other symptoms. After ivermectin therapy, he re-presented with respiratory symptoms, peripheral eosinophilia and transient pulmonary infiltrates; the classic triad of Löffler's syndrome associated with invasive helminth infection...
February 2, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29417800/cutaneous-larva-migrans-and-tungiasis-infestations-of-the-affluent-society
#14
Stefano Veraldi, Gianluca Nazzaro
No abstract text is available yet for this article.
February 7, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29402399/tick-borne-illness-lyme-disease
#15
REVIEW
Larry M Bush, Maria T Vazquez-Pertejo
Lyme disease is the most commonly reported tick-borneillness in the United States. Thecausative spirochete, Borrelia burgdorferi is transmitted by 4 species of Ixodes tick species. Over 90% of US cases occur in northeasternstates from Maine to Virginia, and in Wisconsin, Minnesota, and Michigan. Infection also takes place in northern California and Oregon. Lyme borreliosis is also diagnosed in parts of Europe, China, and Japan. The white-footed mouse is the primary animal reservoir for B. burgdorferi in the U...
February 2, 2018: Disease-a-month: DM
https://www.readbyqxmd.com/read/29398300/-massive-infestation-with-larva-migrans
#16
Tiara Souza Magalhães, Marcello Menta Simonsen Nico
No abstract text is available yet for this article.
February 2, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29394366/amblyomma-americanum-acari-ixodidae-ticks-are-not-vectors-of-the-lyme-disease-agent-borrelia-burgdorferi-spirocheatales-spirochaetaceae-a-review-of-the-evidence
#17
Ellen Y Stromdahl, Robyn M Nadolny, Graham J Hickling, Sarah A Hamer, Nicholas H Ogden, Cory Casal, Garrett A Heck, Jennifer A Gibbons, Taylor F Cremeans, Mark A Pilgard
In the early 1980s, Ixodes spp. ticks were implicated as the key North American vectors of Borrelia burgdorferi (Johnson, Schmid, Hyde, Steigerwalt and Brenner) (Spirocheatales: Spirochaetaceae), the etiological agent of Lyme disease. Concurrently, other human-biting tick species were investigated as potential B. burgdorferi vectors. Rashes thought to be erythema migrans were observed in patients bitten by Amblyomma americanum (L.) (Acari: Ixodidae) ticks, and spirochetes were visualized in a small percentage of A...
January 31, 2018: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29386499/-a-case-of-lyme-neuroborreliosis-without-erythema-migrans
#18
Katsuki Eguchi, Kazuhumi Tsuzaka, Ichiro Yabe, Hidenao Sasaki
A 56-year-old man was sustained ticks at the left axilla and flank. He did not have a rash. About 3 months after the tick bites, he developed back pain, right leg weakness, right abducens nerve palsy, and left facial palsy. Western blot analysis for serum IgM and IgG antibodies against Borrelia were positive. We diagnosed Lyme borreliosis. The patient was treated with antibiotics and steroids, and the symptoms improved. Our findings demonstrate that, even if erythema migrans is not obvious, neuroborreliosis should be considered when neurological signs, such as multiple cranial nerve palsies, are present...
January 31, 2018: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/29385444/oral-doxycycline-versus-intravenous-ceftriaxone-for-treatment-of-multiple-erythema-migrans-an-open-label-alternate-treatment-observational-trial
#19
Daša Stupica, Maša Velušcek, Rok Blagus, Petra Bogovic, Tereza Rojko, Tjaša Cerar, Franc Strle
Background: Several guidelines advocate the same treatment approaches for both early disseminated Lyme borreliosis, manifested as multiple erythema migrans (EM), and early localized Lyme borreliosis, manifested as solitary EM. Methods: Oral doxycycline (100 mg q12h) was compared on a non-inferiority premise with intravenous ceftriaxone (2 g q24h) for 14 days in 200 adult European patients with multiple EM in an open-label alternate-treatment observational trial performed in a single-centre university hospital...
January 29, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29377078/impact-of-climate-change-on-dermatological-conditions-related-to-flooding-update-from-the-international-society-of-dermatology-climate-change-committee
#20
REVIEW
Johannes F Dayrit, Lunardi Bintanjoyo, Louise K Andersen, Mark Dennis P Davis
Climate change contributes to the increase in severity and frequency of flooding, which is the most frequent and deadly disaster worldwide. Flood-related damage can be very severe and include health effects. Among those health impacts, dermatological diseases are one of the most frequently encountered. Both infectious and noninfectious dermatological conditions are increasing after flooding. We searched PubMed using the search term climate change OR global warming OR rainfall OR flooding OR skin. Articles published in the English-language literature were included...
January 29, 2018: International Journal of Dermatology
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