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Barbara Strobino, Katja Steinhagen, Wolfgang Meyer, Thomas Scheper, Sandra Saschenbrecker, Wolfgang Schlumberger, Winfried Stöcker, Andrea Gaito, Brian A Fallon
The objective was to examine the prevalence of Borrelia antibodies among symptomatic individuals with recent and past Lyme disease in endemic communities using standard assays and novel assays employing next-generation antigenic substrates. Single- and two-tiered algorithms included different anti- Borrelia ELISAs and immunoblots. Antibody prevalence was examined in sera from 32 individuals with recent erythema migrans (EM), 335 individuals with persistent symptoms following treatment for Lyme disease (PTLS), and 41 community controls without a history of Lyme disease...
June 19, 2018: Healthcare (Basel, Switzerland)
Zhenzhen Wang, Miho Shibata, Yen Thi Hoang Nguyen, Yayoi Hayata, Nariaki Nonaka, Haruhiko Maruyama, Ayako Yoshida
Ascarid Larva Migrans Syndrome (ascarid LMS) is a clinical syndrome in humans, caused by the migration of animal roundworm larvae such as Toxocara canis, Toxocara cati and Ascaris suum. Humans may acquire infection by ingesting embryonated eggs, or infective larvae of these parasites in contaminated meat and organ meats. To detect these pathogenic contaminations, a novel nested multiplex PCR system was developed. Our novel nested multiplex PCR assay showed specific amplification of T. canis, T. cati and Ascaris spp...
June 16, 2018: Parasitology International
Fernando Alarcon-Soldevilla, Francisco Miguel Gonzalez-Valverde, Eva Cristina Alonso-Osmer, Ángel López-Ávila
No abstract text is available yet for this article.
June 12, 2018: Enfermedades Infecciosas y Microbiología Clínica
Gerold Stanek, Franc Strle
Lyme borreliosis is caused by certain genospecies of the Borrelia burgdorferi sensu lato complex, which are transmitted by hard ticks of the genus Ixodes. The most common clinical manifestation is erythema migrans, an expanding skin redness that usually develops at the site of a tick bite and eventually resolves even without antibiotic treatment. The infecting pathogens can spread to other tissues and organs, resulting in manifestations that can involve the nervous system, joints, heart and skin. Fatal outcome is extremely rare and is due to severe heart involvement; fetal involvement is not reliably ascertained...
May 1, 2018: FEMS Microbiology Reviews
Kesia Backman, Barbro H Skogman
BACKGROUND: Erythema migrans (EM) is the most common manifestation of Lyme borreliosis (LB), caused by the spirochete Borrelia burgdorferi sensu lato. The infection can disseminate into the nervous system and cause Lyme neuroborreliosis (LNB), the second most frequent LB manifestation in children. The aim of this prospective cohort study is to describe the occurrence of EM among children with LNB and to evaluate possible differences in clinical characteristics or outcome between LNB patients with and without EM...
June 11, 2018: BMC Pediatrics
Adil Doğan, Nuray Bayar Muluk, Mehmet Hamdi Şahan, Neşe Asal, Mikail Inal, Ufuk Ergün
OBJECTIVES: To compare the measurements of olfactory bulb volume and olfactory sulcus depth in patients with migraine and a control group. METHODS: The study included the cranial MRI (1.5 T) images of 200 adults diagnosed with migraine and a control group of 100 subjects without migraine. The control group mainly consisted of the patients with non-migraneous headache. The measurements were obtained from coronal T2-weighted images for standard olfactory bulb (OB) volume and olfactory sulcus (OS) depth...
June 6, 2018: European Archives of Oto-rhino-laryngology
Adilson Cardoso de Oliveira, Guita Rubinsky-Elefant, Yslla Fernanda Fitz Balo Merigueti, Aline da Silveira Batista, Vamilton Alvares Santarém
The aim of this study was to evaluate the presence of anti-Toxocara antibodies in naturally infected broiler chickens (n = 189) from the state of Paraná, southern Brazil. The chickens were reared in a semi-intensive system by small family farmers (n = 7). An enzyme-linked immunosorbent assay (ELISA) was performed to detect the presence of anti- Toxocara spp. IgY after serum adsorption with Ascaridia galli antigens. An overall seroprevalence of 67.7% (128/189; 95% CI = 61.1-74.4) was observed. The frequency of positive animals by farm ranged from 29...
May 24, 2018: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
Giovanna Viticchi, Lorenzo Falsetti, Marco Bartolini, Laura Buratti, Alfio Ulissi, Maurizio Baldassari, Leandro Provinciali, Mauro Silvestrini
Migraine is an economically and socially relevant pathology but patients' consciousness and consequently a proper management is often unsatisfactory. In this study, we aimed to evaluate the disease awareness, the general approach and the impact on working activity in a population of headache-affected hospital workers. During an 18-month period, hospital workers responded to a questionnaire investigating headache presence, characteristics and awareness. Specific attention was paid to define headache impact on working activities...
March 30, 2018: Neurology International
Manuela Carneiro, Paula Oliveira, Ricardo Brandão, Vanessa Soeiro, Maria João Pires, Santiago Lavin, Bruno Colaço
Due to their high trophic level, raptor species may serve as important indicators of environmental contamination by heavy metals. This study was conducted to determine if the habitat of the black kite (Milvus migrans) is contaminated by heavy metals and arsenic and to assess the degree and type of exposure that may be present. For this purpose, this study was conducted on a group of captive birds (n = 12) and on a group of free-living birds admitted to two wildlife rehabilitation centers (n = 31). Blood samples were taken for analysis of arsenic (As), mercury (Hg) and lead (Pb) concentrations by inductively coupled plasma mass spectrometry (ICP-MS)...
May 24, 2018: Ecotoxicology and Environmental Safety
Malwina Kaniewska, Lynne S Steinbach, Urs Neurauter, Suzanne E Anderson
We present an uncommon imaging feature with fluid fat tracking within the tendon sheath of the flexor hallucis longus (FHL) after traumatic injury to the ankle joint. We propose a coined medical term "lipidus migrans" to define the presence of floating fat in a tendon sheath. This is due to lipohemarthrosis from intra-articular fracture of the ankle with leakage of fluid fat into the tendon sheath. Communication between the FHL tendon sheath and ankle joint can occur in up to 25% of patients. Radiologists should be aware of the presence of lipidus migrans as a potential posttraumatic complication after intra-articular ankle fracture and that fat in the tendon sheath may mimic fracture fragments or even a tendon sheath tumor...
May 21, 2018: Skeletal Radiology
S Gasmi, N H Ogden, L R Lindsay, S Burns, S Fleming, J Badcock, S Hanan, C Gaulin, M A Leblanc, C Russell, M Nelder, L Hobbs, S Graham-Derham, L Lachance, A N Scott, E Galanis, J K Koffi
Objective: To summarize seven years of surveillance data for Lyme disease cases reported in Canada from 2009 to 2015. Methods: We describe the incidence over time, seasonal and geographic distribution, demographic and clinical characteristics of reported Lyme disease cases. Logistic regression was used to explore differences between age groups, sex and year to better understand potential demographic risk factors for the occurrence of Lyme disease. Results: The number of reported Lyme disease cases increased more than six-fold, from 144 in 2009 to 917 in 2015, mainly due to an increase in infections acquired in Canada...
October 5, 2017: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
Alessandro Traniello Gradassi, Carlotta Gurioli, Stefania Barruscotti, Iria Neri
No abstract text is available yet for this article.
June 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
Masafumi Seki, Yuji Watanabe, Hiroki Kawabata
This report presents the case of a Japanese patient who developed Lyme disease. The patient was a 44-year-old woman who had general fatigue and the inability to open her mouth. She was initially suspected of having mild tetanus with lockjaw; however, she reported a past history of a tick bite while camping in the USA and had erythema migrans 2 months before this visit. Finally, Lyme disease was serologically confirmed. A few cases of Lyme disease are annually reported in Japan; however, this infectious disease should also be suspected...
2018: Infection and Drug Resistance
Mateusz Markowicz, Anna-Margarita Schötta, Michael Kundi, Petra Bogovič, Katarina Ogrinc, Franc Strle, Gerold Stanek
The aims of the study were to determine and compare the concentration of CXCL13 in cerebrospinal fluid (CSF) of patients with Lyme neuroborreliosis (LNB) and various other neurological disorders applying a Luminex based assay and ELISA, and to find factors associated with CXCL13 concentration. CSF samples obtained from four clinically well-defined groups of patients (proven LNB, suspected LNB, tick-borne encephalitis (TBE), and aseptic meningitis/meningoencephalitis other than TBE) - 25 samples per group - were analyzed...
April 20, 2018: Ticks and Tick-borne Diseases
Kensuke Taira, Shohei Nakamura, Toshihiro Tokiwa, Yumi Une
Occurrence of clinical signs by infection with Baylisascaris potosis, the roundworm of kinkajous (Potos flavus), in mice, rats and rabbit were studied, and the migration behavior of larvae in mice were compared with that of B. transfuga the round worm of bears (Ursus spp.). Three groups of 8 mice, 3 groups of 6 rats and 3 groups of 2 rabbits were inoculated with either 10, 100 or 1,000 B. potosis eggs. The other 8 mice were inoculated with 1,000 B. transfuga eggs. Animals were monitored for occurrence of clinical signs until 60 days post-inoculation (DPI)...
May 15, 2018: Journal of Parasitology
Fernando da Silva Carvalho-Filho, Gabriela Pirani, Thiago Gechel Kloss
A new species of Cladochaeta Coquillett (Diptera: Drosophilidae) is described, C. caxiuana sp. nov. from the Brazilian Amazon, based on 10 male and 10 female specimens obtained from nymphs of Sphodroscarta trivirgata (Amyot Serville, 1843) (Hemiptera: Auchenorrhyncha: Aphrophoridae). The female of Cladochaeta atlantica Pirani Amorim, 2016 is described based on specimens reared from spider egg sacs of the spider Cryptachaea migrans (Keyserling, 1884) (Araneae: Theridiidae) obtained in the state of Espírito Santo, Brazil...
April 18, 2018: Zootaxa
Lyudmila Karan, Marat Makenov, Nadezhda Kolyasnikova, Olga Stukolova, Marina Toporkova, Olga Olenkova
We investigated whether Borrelia miyamotoi disease can be detected in its early stage by using PCR for borrelial 16S rRNA, which molecule (DNA or RNA) is the best choice for this test, and whether spirochetes are present in blood during the acute phase of B. miyamotoi disease. A total of 473 patients with a suspected tickborne infection in Yekaterinburg, Russia, in 2009, 2010, and 2015 were enrolled in this study. Blood samples were analyzed by using quantitative PCR or ELISA, and a diagnosis of borreliosis was confirmed for 310 patients...
May 2018: Emerging Infectious Diseases
Manu Sehrawat, Niharika Dixit, Kabir Sardana, Purnima Malhotra
Erythema nodosum migrans (subacute nodular migratory panniculitis) is an uncommon type of panniculitis characterized by migrating subcutaneous nodules or plaque on the lower extremity. There are a very few cases of Erythema nodosum migrans reported and thus its appropriate treatment modality is not defined. We describe a case of a 30-year-old male with idiopathic erythema nodosum migrans which was manifest centrifugally spreading, slightly morpheaform erythematous plaque on the lower left leg. The patient was diagnosed initially and treated as a case of furunculosis with poor clinical response...
April 11, 2018: Dermatologic Therapy
Bruno Gualtieri, Roberto Maglie, Annalisa Tonini, Salvatore Panduri, Andrea Chiricozzi, Marco Romanelli
No abstract text is available yet for this article.
March 29, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
Sara G Rimoldi, Stefania Merli, Giovanna Bestetti, Vania Giacomet, Giuliana Cislaghi, Romualdo Grande, Sergio Sanzani, Cristina Pagani, Giusto Trevisan, Eleonora DE Faveri, Maria R Gismondo, Eva Ruzić-Sabljić
BACKGROUND: In Italy, the incidence of human tick borne disease has increased over the last decades. Since 2015 a multidisciplinary group has been established in Sacco Hospital for the management of the patients affected by Lyme Disease (LD). A retrospective evaluation (2015-2017) was performed for LD in non-endemic areas. METHODS: Retrospective analysis of all 1000 samples for 800 patients screened for LD antibodies at the Sacco Hospital in 3 years (2015-2017)...
March 29, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
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