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https://www.readbyqxmd.com/read/28533930/early-onset-lyme-carditis-with-concurrent-disseminated-erythema-migrans
#1
Kinjan P Patel, Peter D Farjo, Joy J Juskowich, Ali Hama Amin, James D Mills
BACKGROUND: Lyme disease is an infection that is estimated to affect over 300,000 people in the United States annually. Typically, it presents with erythema migrans (EM), an annular rash at the site of tick attachment, within 3 to 30 days of inoculation. Untreated patients may progress to early disseminated disease. A further complication, Lyme carditis is rare but may occur several weeks later. It commonly manifests as a variable atrioventricular (AV) conduction block, with a high-grade AV block occurring in only 1% of untreated patients...
2017: American Journal of Cardiovascular Disease
https://www.readbyqxmd.com/read/28532428/practices-of-lyme-disease-diagnosis-and-treatment-by-general-practitioners-in-quebec-2008-2015
#2
Salima Gasmi, Nicholas H Ogden, Patrick A Leighton, Ariane Adam-Poupart, François Milord, L Robbin Lindsay, Sapha Barkati, Karine Thivierge
BACKGROUND: Lyme disease (LD), a multisystem infection caused by the spirochete Borrelia burgdorferi sensu stricto (B. burgdorferi), is the most reported vector-borne disease in North America, and by 2020, 80% of the population in central and eastern Canada could live in LD risk areas. Among the key factors for minimising the impact of LD are the accurate diagnosis and appropriate management of patients bitten by ticks. In this study, the practices of Quebec general practitioners (GPs) on LD diagnosis and management of patients bitten by infected ticks are described...
May 22, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28529879/beyond-the-raccoon-roundworm-the-natural-history-of-non-raccoon-baylisascaris-species-in-the-new-world
#3
REVIEW
Sarah G H Sapp, Pooja Gupta, Melissa K Martin, Maureen H Murray, Kevin D Niedringhaus, Madeleine A Pfaff, Michael J Yabsley
A total of 10 species of Baylisascaris, a genus of ascaridoid nematodes, occur worldwide and 6 of them occur in the New World. Most of the Baylisascaris species have a similar life cycle with carnivorous mammals or marsupials serving as definitive hosts and a smaller prey host serving as paratenic (or intermediate) hosts. However, one species in rodents is unique in that it only has one host. Considerable research has been conducted on B. procyonis, the raccoon roundworm, as it is a well-known cause of severe to fatal neurologic disease in humans and many wildlife species...
August 2017: International Journal for Parasitology. Parasites and Wildlife
https://www.readbyqxmd.com/read/28508758/cutaneous-larva-migrans-a-case-in-bordeaux-france-and-a-systematic-review-of-locally-acquired-cases-in-europe
#4
Romain Blaizot, Anne Goiset, Eric Caumes, Frederic Gabriel, Brigitte Milpied
No abstract text is available yet for this article.
May 16, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/28503499/the-prevalence-of-osmophobia-in-migranous-and-episodic-tension-type-headaches
#5
Ahmad Chitsaz, Abbas Ghorbani, Masoumeh Dashti, Mohsen Khosravi, Mohammadreza Kianmehr
BACKGROUND: Migraines are a neurological disease, of which the most common symptom is an intense and disabling episodic headache. Many persons experience sensory hyper excitability manifested by photophobia, phonophobia and osmophobia. This study was planned to investigate the prevalence of osmophobia in migranous and episodic tension type headache (ETTH). MATERIALS AND METHODS: A semi-structured questionnaire was administered to all patients to evaluate the eventual presence of osmophobia during a headache attack and different characteristics of osmophobia were determined...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28497257/-therapy-of-migranes
#6
D Holle-Lee, S Nägel, C Gaul
In migraine attack treatment analgesics such as nonsteroidal anti-inflammatory drugs and triptans can be utilized. The efficacy of acute attack treatment is relevant to prevent migraine chronification. For prophylactic treatment β‑blockers, tricyclic antidepressants, flunarizine, antiepileptics and onabotulinumtoxin A are available. There is evidence that some other substances (e. g. sartans) are also efficacious in this regard. Furthermore, nondrug approaches are essential in migraine therapy. Early education and prophylactic treatment of patients at risk may prevent from medication overuse headache...
May 11, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28477306/duration-and-frequency-of-migraines-affect-cognitive-function-evidence-from-neuropsychological-tests-and-event-related-potentials
#7
Lifang Huang, Hong Juan Dong, Xi Wang, Yan Wang, Zheman Xiao
BACKGROUND: The aim of this study was to evaluate the changes in the cognitive performance of migraine patients using a comprehensive series of cognitive/behavioral and electrophysiological tests. METHOD: A randomized, cross-sectional, within subject approach was used to compare neuropsychological and electrophysiological evaluations from migrane-affected and healthy subjects. RESULTS: Thirty-four patients with migraine (6 males, 28 females, average 36 years old) were included...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28473022/-clinical-manifestations-diagnosis-and-treatment-of-lyme-borreliosis
#8
Lukas Frans Ocias, Bo Bødker Jensen, Fredrikke Christie Knudtzen, Sigurdur Skarphedinsson, Ram Benny Dessau
Lyme borreliosis is an infection caused by the Borrelia burgdorferi sensu lato complex and transmitted by Ixodes ricinus ticks in Denmark. It can manifest itself in several different forms of which erythema migrans is the most common and is diagnosed by clinical assessment of the characteristic erythema. Laboratory support for the clinical diagnosis of other manifestations rests on the measurement of Borrelia-specific antibodies. Treatment is straight-forward with antibiotics such as penicillin. This paper reviews the clinical manifestations, diagnosis and treatment of this infection...
May 1, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28457701/primary-care-physician-management-of-tick-bites-in-the-franche-comt%C3%A3-region-eastern-france-2013
#9
C Vandererven, A-P Bellanger, J-F Faucher, P Marguet
INTRODUCTION: Tick bites, which may lead to Lyme disease, often prompt patients to consult their primary care physicians (PCPs). The aim of the present study was to assess how and how often PCPs in the Franche-Comté region of France manage tick bites. MATERIAL AND METHODS: Standardized questionnaires were sent to a random sample of 400 PCPs in the Franche-Comté region, requesting their voluntary and anonymous participation. The questionnaires collected socio-demographic details and practice-related information about tick-bite prophylaxis, Lyme serology, and tick-borne encephalitis vaccination...
April 27, 2017: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/28457619/borrelia-burgdorferi-specific-iga-in-lyme-disease
#10
Christina D'Arco, Raymond J Dattwyler, Paul M Arnaboldi
The laboratory diagnosis of Lyme disease is currently dependent on the detection of IgM and IgG antibodies against Borrelia burgdorferi, the causative agent of the disease. The significance of serum IgA against B. burgdorferi remains unclear. The production of intrathecal IgA has been noted in patients with the late Lyme disease manifestation, neuroborreliosis, but production of antigen-specific IgA during early disease has not been evaluated. In the current study, we assessed serum IgA binding to the B. burgdorferi peptide antigens, C6, the target of the FDA-cleared C6 EIA, and FlaB(211-223)-modVlsE(275-291), a peptide containing a Borrelia flagellin epitope linked to a modified VlsE sequence, in patients with early and late Lyme disease...
April 21, 2017: EBioMedicine
https://www.readbyqxmd.com/read/28444236/the-cost-of-lyme-borreliosis
#11
Cees C van den Wijngaard, Agnetha Hofhuis, Albert Wong, Margriet G Harms, G Ardine de Wit, Anna K Lugnér, Anita W M Suijkerbuijk, Marie-Josée J Mangen, Wilfrid van Pelt
Lyme borreliosis (LB) is the most frequently reported tick-borne infection in Europe and North America. The aim of this study was to estimate the cost-of-illness of LB in the Netherlands. We used available incidence estimates from 2010 for tick bite consultations and three symptomatic LB outcomes: erythema migrans (EM), disseminated LB and Lyme-related persisting symptoms. The cost was estimated using these incidences and the average cost per patient as derived from a patient questionnaire. We estimated the cost from a societal perspective, including healthcare cost, patient cost and production loss, using the friction cost method and a 4% annual discount rate...
April 24, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28438141/prevalence-of-toxocara-antibodies-among-patients-clinically-suspected-to-have-ocular-toxocariasis-a-retrospective-descriptive-study-in-sri-lanka
#12
Devika Iddawela, Kiruthiha Ehambaram, Pemindra Bandara
BACKGROUND: Human toxocariasis, caused by Toxocara canis, T. cati, and T. vitulorum of dogs, cats and ruminants respectively, is recognized as an important zoonotic infection worldwide. The typical clinical syndromes of toxocariasis in humans are ocular larva migrans (OLM) and visceral larva migrans (VLM). The most commonly affected sites of OLM are the peripheral retina and/or vitreous humor. In Sri Lanka, there is a dearth of information on prevalence of ocular infection in our population...
April 24, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28432859/the-impact-of-global-climate-change-on-the-spread-of-parasitic-nematodes
#13
Anna Okulewicz
Climate changes may influence the frequency, intensity and geographical distribution of parasites, directly affecting their dispersive stages in the environment (eggs, larvae) and, indirectly, the larvae living mainly in invertebrate intermediate hosts. In biologically diverse nematodes climate warming contributes to the increase in the range of distribution, colonization of new hosts and modification of their development cycles. This is particularly acute in the Arctic and pertains, for instance, to nematodes Ostertagia gruehneri and Setaria tundra parasitizing reindeer Rangifer tarandus and Umingmakstrongylus pallikuukensis in musk oxen (Ovibos moschatus)...
2017: Annals of Parasitology
https://www.readbyqxmd.com/read/28426425/the-role-of-domestic-dogs-in-the-transmission-of-zoonotic-helminthes-in-a-rural-area-of-mekong-river-basin
#14
Marcello Otake Sato, Megumi Sato, Tippayarat Yoonuan, Tiengkham Pongvongsa, Surapol Sanguankiat, Sengchanh Kounnavong, Wanna Maipanich, Yuichi Chigusa, Kazuhiko Moji, Jitra Waikagul
Dogs have been bred since ancient times for companionship, hunting, protection, shepherding and other human activities. Some canine helminth parasites can cause significant clinical diseases in humans as Opisthorchis viverrini causing cholangiocarcinoma in Southeast Asian Countries. In this study, socio-cultural questionnaire, canine parasitological analysis, necropsy, parasite molecular confirmation and dog roaming data were evaluated in Savannakhet, Lao-PDR, a typical Mekong Basin area. Dog owners comprised 48...
June 1, 2017: Acta Parasitologica
https://www.readbyqxmd.com/read/28409581/therapy-of-cutaneous-larva-migrans-in-pregnancy
#15
Stefano Veraldi, Betsabet A Parducci, Paolo Pontini
No abstract text is available yet for this article.
June 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28405553/lyme-disease-a-case-report-with-typical-and-atypical-lesions
#16
Anuj Sharma, Sandesh Guleria, Reena Sharma, Anita Sharma
Lyme disease is a multisystem infectious disease caused by the spirochete "Borrelia burgdorferi," which is transmitted by "Ixodes" tick, with skin being the most common and earliest organ to be affected. Diagnosis of erythema chronicum migrans (ECM), which is the characteristic lesion of early disease, may help in early treatment and prevention of complications. Here, we are reporting a case of Lyme disease in a 10-year-old young boy from a non-endemic zone of Himachal Pradesh, who presented with typical as well as atypical ECM lesions...
March 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28383628/interferon-%C3%AE-induced-protein-10-in-lyme-disease
#17
P Fallahi, G Elia, A Bonatti
Lyme disease is an infectious disease caused by bacteria of the Borrelia type, that affects about 300,000 people a year in the USA and 65,000 people a year in Europe. Borrelia infection, and Lyme disease, following occupational exposure has been frequently reported in USA, Europe and Asia. The manifestations of Lyme disease include erythema migrans (EM), arthritis, neuroborrelliosis (NB), and others. Cytokines and chemokines primarily orchestrate leukocyte recruitment to the areas of Borrelia infection, and they are critical mediators of immune and inflammatory responses, in particular of the induction of interferon (IFN)-γ and IFN-γ dependent chemokines...
March 2017: La Clinica Terapeutica
https://www.readbyqxmd.com/read/28363038/baylisascaris-procyonis-larva-migrans-in-two-captive-north-american-beavers-castor-canadensis
#18
Isabelle Desprez, Michael J Yabsley, Susan B Fogelson, Jill A Hicks, Renee Barber, Izidora Sladakovic, Scott A Secrest, Stephen J Divers, Jörg Mayer
Baylisascaris procyonis larva migrans was diagnosed in two North American beavers ( Castor canadensis ) belonging to a zoological park in Clarke County, Georgia. Both beavers presented with neurological signs. One beaver died naturally and despite attempted treatment, the other beaver was euthanatized because of severe clinical signs and poor prognosis. Histologic evaluation of the beavers revealed evidence of parasitic migration characterized by several lesions, including eosinophilic granulomas in various organs, as well as necrotizing eosinophilic and lymphoplasmacytic to granulomatous polioencephalitis, leukoencephalitis and cervical leukomyelitis...
March 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28338526/cutaneous-larva-migrans-associated-with-l%C3%A3-ffler-s-syndrome-in-a-6-year-old-boy
#19
Shan Wang, Wei Xu, Lin-Feng Li
Cutaneous larva migrans is a frequent dermatologic problem among travelers in tropical areas, but its association with Löffler's syndrome is an extremely rare condition, particularly in children. Here, we describe a 6-year old boy presenting cutaneous larva migrans associated with Löffler's syndrome.
March 23, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28329259/evaluation-of-modified-2-tiered-serodiagnostic-testing-algorithms-for-early-lyme-disease
#20
John A Branda, Klemen Strle, Lise E Nigrovic, Paul M Lantos, Timothy J Lepore, Nitin S Damle, Mary Jane Ferraro, Allen C Steere
Background.: The conventional 2-tiered serologic testing protocol for Lyme disease (LD), an enzyme immunoassay (EIA) followed by immunoglobulin M and immunoglobulin G Western blots, performs well in late-stage LD but is insensitive in patients with erythema migrans (EM), the most common manifestation of the illness. Western blots are also complex, difficult to interpret, and relatively expensive. In an effort to improve test performance and simplify testing in early LD, we evaluated several modified 2-tiered testing (MTTT) protocols, which use 2 assays designed as first-tier tests sequentially, without the need of Western blots...
April 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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