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https://www.readbyqxmd.com/read/29166295/nursing-care-of-infants-with-a-ventriculoperitoneal-shunt
#1
Rachel A Joseph, Michaela R Killian, Emily E Brady
BACKGROUND: Infants with congenital or posthemorrhagic hydrocephalus may require a ventriculoperitoneal (VP) shunt to divert the flow of cerebrospinal fluid, thus preventing increase in intracranial pressure. Knowledge on various aspects of caring for a child with a VP shunt will enable new and experienced nurses to better care for these infants and equip parents for ongoing care at home. PURPOSE: To review the nurses' role in care of infants with hydrocephalus, care after VP shunt placement, prevention of complications, and parental preparation for home care...
November 20, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/29155684/births-in-the-united-states-2016
#2
Joyce A Martin, Brady E Hamilton, Michelle J K Osterman
Key findings Data from the National Vital Statistics System ● The U.S. general fertility rate declined to 62.0 births per 1,000 women aged 15-44 in 2016, down 1% from 2015. ● Birth rates declined among women under age 30 in 2016, and rose for women aged 30-44. ● The cesarean delivery rate continued to decline in 2016, down to 31.9% of all births. ● The preterm birth rate rose for the second straight year to 9.85% in 2016. ● The 2016 rate of triplet and higher-order multiple births was 48% lower than the 1998 peak...
September 2017: NCHS Data Brief
https://www.readbyqxmd.com/read/29151874/incorporating-evolutionary-insights-to-improve-ecotoxicology-for-freshwater-species
#3
Steven P Brady, Jonathan L Richardson, Bethany K Kunz
Ecotoxicological studies have provided extensive insights into the lethal and sublethal effects of environmental contaminants. These insights are critical for environmental regulatory frameworks, which rely on knowledge of toxicity for developing policies to manage contaminants. While varied approaches have been applied to ecotoxicological questions, perspectives related to the evolutionary history of focal species or populations have received little consideration. Here, we evaluate chloride toxicity from the perspectives of both macroevolution and contemporary evolution...
September 2017: Evolutionary Applications
https://www.readbyqxmd.com/read/29151867/evolutionary-toxicology-toward-a-unified-understanding-of-life-s-response-to-toxic-chemicals
#4
EDITORIAL
Steven P Brady, Emily Monosson, Cole W Matson, John W Bickham
No abstract text is available yet for this article.
September 2017: Evolutionary Applications
https://www.readbyqxmd.com/read/29149389/autoregulation-in-paediatric-tbi-current-evidence-and-implications-for-treatment
#5
REVIEW
Joseph E Donnelly, Adam M H Young, Ken Brady
BACKGROUND: Children who survive acute traumatic brain injury are at risk of death from subsequent brain swelling and secondary injury. Strict physiologic management in the ICU after traumatic brain injury is believed to be key to survival, and cerebral perfusion pressure is a prominent aspect of post brain injury care. However, optimal cerebral perfusion pressure targets for children are not known. Autoregulation monitoring has been used to delineate individualized optimal perfusion pressures for patients with traumatic brain injury...
October 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29148355/vertical-integration-of-hospitals-and-physicians-economic-theory-and-empirical-evidence-on-spending-and-quality
#6
Brady Post, Tom Buchmueller, Andrew M Ryan
Hospital-physician vertical integration is on the rise. While increased efficiencies may be possible, emerging research raises concerns about anticompetitive behavior, spending increases, and uncertain effects on quality. In this review, we bring together several of the key theories of vertical integration that exist in the neoclassical and institutional economics literatures and apply these theories to the hospital-physician relationship. We also conduct a literature review of the effects of vertical integration on prices, spending, and quality in the growing body of evidence ( n = 15) to evaluate which of these frameworks have the strongest empirical support...
August 1, 2017: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/29146842/genome-sequences-of-19-novel-erwinia-amylovora-bacteriophages
#7
Ian N D Esplin, Jordan A Berg, Ruchira Sharma, Robert C Allen, Daniel K Arens, Cody R Ashcroft, Shannon R Bairett, Nolan J Beatty, Madeline Bickmore, Travis J Bloomfield, T Scott Brady, Rachel N Bybee, John L Carter, Minsey C Choi, Steven Duncan, Christopher P Fajardo, Brayden B Foy, David A Fuhriman, Paul D Gibby, Savannah E Grossarth, Kala Harbaugh, Natalie Harris, Jared A Hilton, Emily Hurst, Jonathan R Hyde, Kayleigh Ingersoll, Caitlin M Jacobson, Brady D James, Todd M Jarvis, Daniella Jaen-Anieves, Garrett L Jensen, Bradley K Knabe, Jared L Kruger, Bryan D Merrill, Jenny A Pape, Ashley M Payne Anderson, David E Payne, Malia D Peck, Samuel V Pollock, Micah J Putnam, Ethan K Ransom, Devin B Ririe, David M Robinson, Spencer L Rogers, Kerri A Russell, Jonathan E Schoenhals, Christopher A Shurtleff, Austin R Simister, Hunter G Smith, Michael B Stephenson, Lyndsay A Staley, Jason M Stettler, Mallorie L Stratton, Olivia B Tateoka, P J Tatlow, Alexander S Taylor, Suzanne E Thompson, Michelle H Townsend, Trever L Thurgood, Brittian K Usher, Kiara V Whitley, Andrew T Ward, Megan E H Ward, Charles J Webb, Trevor M Wienclaw, Taryn L Williamson, Michael J Wells, Cole K Wright, Donald P Breakwell, Sandra Hope, Julianne H Grose
Erwinia amylovora is the causal agent of fire blight, a devastating disease affecting some plants of the Rosaceae family. We isolated bacteriophages from samples collected from infected apple and pear trees along the Wasatch Front in Utah. We announce 19 high-quality complete genome sequences of E. amylovora bacteriophages.
November 16, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29146379/lt-adjuvant-modulates-epitope-specificity-and-improves-the-efficacy-of-murine-antibodies-elicited-by-sublingual-vaccination-with-the-n-terminal-domain-of-streptococcus-mutans-p1
#8
Milene Tavares Batista, Ewerton Lucena Ferreira, Gisela de Souza Pereira, Phillip Stafford, Denicar Lina Nascimento Fabris Maeda, Juliana Falcão Rodrigues, L Jeannine Brady, Stephen Albert Johnston, Luís Carlos de Souza Ferreira, Rita de Cássia Café Ferreira
In this study, we evaluated the immunogenicity, protective efficacy and peptide-based immune signatures of antibodies raised in mice after sublingual immunization with a recombinant form of the P1 (aka AgI/II, PAc) adhesin (P139-512) of Streptococcus mutans, a major etiological agent of dental caries. Sublingual administration of P139-512 in combination with the mucosal adjuvant LTK4R (a derivative of heat-labile LT toxin) induced strong and long-lasting systemic and mucosal immune responses. Incorporation of the adjuvant resulted in an enhancement of the anti-adhesive and anti-colonization activity against S...
November 13, 2017: Vaccine
https://www.readbyqxmd.com/read/29146165/preliminary-results-of-arthroscopic-superior-capsule-reconstruction-with-dermal-allograft
#9
Patrick J Denard, Paul C Brady, Christopher R Adams, John M Tokish, Stephen S Burkhart
PURPOSE: The purpose of this study was to evaluate the short-term outcomes of arthroscopic superior capsule reconstruction (SCR) with dermal allograft for the treatment of irreparable massive rotator cuff tears (MRCTs). METHODS: A multicenter study was performed on patients undergoing arthroscopic SCR for irreparable MRCTs. The minimum follow-up was 1 year. Range of motion and functional outcome according to visual analog scale (VAS) pain, American Shoulder and Elbow Surgeons (ASES) score, and subjective shoulder value (SSV) score were assessed preoperatively and at final follow-up...
November 13, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29146164/magnetic-resonance-imaging-validation-of-tibial-tubercle-transfer-distance-in-the-fulkerson-osteotomy-a-clinical-and-cadaveric-study
#10
Joseph N Liu, Douglas N Mintz, Joseph T Nguyen, Jacqueline M Brady, Sabrina M Strickland, Beth E Shubin Stein
PURPOSE: To validate the medialization and anteriorization distances, and the osteotomy angle of anteromedialization tibial tubercle osteotomies using postoperative axial imaging. METHODS: From March 2004 to August 2015, 117 consecutive patients who underwent anteromedialization osteotomies of the tibial tubercle by a single surgeon were identified. Only patients with pre- and postoperative magnetic resonance imaging (MRI) studies were included. Using MRI multiplanar reformats, distances that the tibial tubercle was translated medially (medialization) and anteriorly (anteriorization) were measured...
November 13, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29144539/model-based-evaluation-of-proximal-sodium-reabsorption-through-sglt2-in-health-and-diabetes-and-the-effect-of-inhibition-with-canagliflozin
#11
Jessica A Brady, K Melissa Hallow
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce glucose levels in diabetes by inhibiting renal glucose reabsorption in the proximal tubule (PT), resulting in urinary glucose excretion. A recent large cardiovascular outcomes trial suggested that the SGLT2i empagliflozin may also decrease risk of renal dysfunction. Because sodium (Na) and glucose reabsorption are coupled through SGLT2, it is hypothesized that the renal benefits may be derived from lowering Na reabsorption in the PT, which would lead to favorable renal hemodynamic changes...
November 16, 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29141844/architectural-t-wave-analysis-and-identification-of-on-therapy-breakthrough-arrhythmic-risk-in-type-1-and-type-2-long-qt-syndrome
#12
Alan Sugrue, Ram K Rohatgi, Peter A Noseworthy, Vaclav Kremen, J Martijn Bos, Bo Qiang, Yehu Sapir, Zachi I Attia, Christopher G Scott, Peter Brady, Samuel J Asirvatham, Paul A Friedman, Michael J Ackerman
BACKGROUND: Although the hallmark of long-QT syndrome (LQTS) is abnormal cardiac repolarization, there are varying degrees of phenotypic expression and arrhythmic risk. Our aim was to evaluate the performance of a morphological T-wave analysis program in defining breakthrough LQTS arrhythmic risk beyond the QTc value. METHODS AND RESULTS: We analyzed 407 genetically confirmed patients with LQT1 (n=246; 43% men) and LQT2 (n=161; 41% men) over the mean follow-up period of 6...
November 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29140170/clinical-diagnostic-tests-versus-mri-diagnosis-of-acl-tears
#13
Megan P Brady, Windee Weiss
CLINICAL SCENARIO: A common injury among elite, recreational, and youth athletes is the anterior cruciate ligament (ACL) tear.(1) Approximately 200,000 ACL injuries occur every year.(2) The gold standard in ACL injury evaluation is diagnostic arthroscopy,(3,4) however the diagnostic accuracy of clinical diagnostic tests and magnetic resonance imaging (MRI) is debatable.(1,3-6) Due to the frequency of knee injury,(3) MRI is a common diagnostic tool used for imaging and diagnosis(5). ACL tears are also diagnosed using clinical diagnostic tests...
November 15, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/29138437/photosensitized-ina-labelled-protein-1-phil1-is-novel-component-of-the-inner-membrane-complex-and-is-required-for-plasmodium-parasite-development
#14
Ekta Saini, Mohammad Zeeshan, Declan Brady, Rajan Pandey, Gesine Kaiser, Ludek Koreny, Pradeep Kumar, Vandana Thakur, Shreyansh Tatiya, Nicholas J Katris, Rebecca Stanway Limenitakis, Inderjeet Kaur, Judith L Green, Andrew R Bottrill, David S Guttery, Ross F Waller, Volker Heussler, Anthony A Holder, Asif Mohmmed, Pawan Malhotra, Rita Tewari
Plasmodium parasites, the causative agents of malaria, possess a distinctive membranous structure of flattened alveolar vesicles supported by a proteinaceous network, and referred to as the inner membrane complex (IMC). The IMC has a role in actomyosin-mediated motility and host cell invasion. Here, we examine the location, protein interactome and function of PhIL1, an IMC-associated protein on the motile and invasive stages of both human and rodent parasites. We show that PhIL1 is located in the IMC in all three invasive (merozoite, ookinete-, and sporozoite) stages of development, as well as in the male gametocyte and locates both at the apical and basal ends of ookinete and sporozoite stages...
November 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29138300/high-zika-virus-seroprevalence-in-salvador-northeastern-brazil-limits-the-potential-for-further-outbreaks
#15
Eduardo Martins Netto, Andres Moreira-Soto, Celia Pedroso, Christoph Höser, Sebastian Funk, Adam J Kucharski, Alexandra Rockstroh, Beate M Kümmerer, Gilmara Souza Sampaio, Estela Luz, Sara Nunes Vaz, Juarez Pereira Dias, Fernanda Anjos Bastos, Renata Cabral, Thomas Kistemann, Sebastian Ulbert, Xavier de Lamballerie, Thomas Jaenisch, Oliver J Brady, Christian Drosten, Manoel Sarno, Carlos Brites, Jan Felix Drexler
During 2015 to 2016, Brazil reported more Zika virus (ZIKV) cases than any other country, yet population exposure remains unknown. Serological studies of ZIKV are hampered by cross-reactive immune responses against heterologous viruses. We conducted serosurveys for ZIKV, dengue virus (DENV), and Chikungunya virus (CHIKV) in 633 individuals prospectively sampled during 2015 to 2016, including microcephaly and non-microcephaly pregnancies, HIV-infected patients, tuberculosis patients, and university staff in Salvador in northeastern Brazil using enzyme-linked immunosorbent assays (ELISAs) and plaque reduction neutralization tests...
November 14, 2017: MBio
https://www.readbyqxmd.com/read/29135851/the-impact-of-an-electronic-medication-administration-record-emar-and-computerized-physician-order-entry-cpoe-on-nurse-extender-and-unit-clerk-staffing
#16
Edmondo J Robinson, Meredith R Bergey, Elizabeth Brady, Alexandra M Mapp, Jennifer C Goldsack
OBJECTIVE: The aim of this study is to describe the impact of the introduction of health information technology (HIT) on the utilization and payroll costs of nurse extenders and unit clerks in medicine and surgery units in a large regional health system. BACKGROUND: Long-term policy goals of HIT implementation are reported to include system-level reductions in labor costs, achieved through improved efficiency. METHODS: Using a retrospective cohort model, we analyzed how hours worked per patient day and staffing costs per patient day varied with the implementation of HIT over time at 2 different hospitals within a health system...
December 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/29135600/balance-and-functional-outcomes-for-older-community-dwelling-adults-who-practice-tai-chi-and-those-who-do-not-a-comparative-study
#17
Deborah Bubela, Laddie Sacharko, Judy Chan, Maegen Brady
BACKGROUND AND PURPOSE: A growing body of literature substantiates that Tai Chi is a form of exercise that may help older adults increase strength, improve balance, lower fall rates, and experience less fear of falling. Few studies, however, offer controlled experimental design and simultaneously investigate multiple factors known to contribute to fall risk. The purpose of this study was to compare performance on measures relating to fall risk (strength, balance, functional mobility, and fear of falling) in older community-dwelling adults who participated in a community-based Tai Chi program with a control group of their peers who had no Tai Chi training over the same time period...
November 9, 2017: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/29131829/a-non-linear-data-mining-parameter-selection-algorithm-for-continuous-variables
#18
Peyman Tavallali, Marianne Razavi, Sean Brady
In this article, we propose a new data mining algorithm, by which one can both capture the non-linearity in data and also find the best subset model. To produce an enhanced subset of the original variables, a preferred selection method should have the potential of adding a supplementary level of regression analysis that would capture complex relationships in the data via mathematical transformation of the predictors and exploration of synergistic effects of combined variables. The method that we present here has the potential to produce an optimal subset of variables, rendering the overall process of model selection more efficient...
2017: PloS One
https://www.readbyqxmd.com/read/29129780/prior-radiation-therapy-decreases-time-to-idiopathic-erosion-of-artificial-urinary-sphincter-a-multi-institutional-analysis
#19
Melissa R Kaufman, Douglas F Milam, Niels V Johnsen, Mario A Cleves, Joshua A Broghammer, William O Brant, LeRoy A Jones, Jeffrey D Brady, Martin S Gross, Gerard D Henry
PURPOSE: Substantial controversy and conflicting data exist regarding device survival of the artificial urinary sphincter (AUS) in patients with prior radiation therapy. Herein we present data from a multi-institutional analysis examining the effect of prior radiation for prostate cancer on device survival. MATERIALS AND METHODS: A database was compiled of AUS cuff erosion patients including demographic and comorbid patient characteristics, functional analyses, and interventions...
November 9, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29129525/multicenter-evaluation-of-the-clinical-utility-of-laparoscopy-assisted-ercp-in-patients-with-roux-en-y-gastric-bypass
#20
Ali M Abbas, Andrew T Strong, David L Diehl, Brian C Brauer, Iris H Lee, Rebecca Burbridge, Jaroslav Zivny, Jennifer T Higa, Marcelo Falcão, Ihab I El Hajj, Paul Tarnasky, Brintha K Enestvedt, Alexander R Ende, Adarsh M Thaker, Rishi Pawa, Priya Jamidar, Kartik Sampath, Eduardo Guimarães Hourneaux de Moura, Richard S Kwon, Alejandro L Suarez, Murad Aburajab, Andrew Y Wang, Mohammad H Shakhatreh, Vivek Kaul, Lorna Kang, Thomas E Kowalski, Rahul Pannala, Jeffrey Tokar, A Aziz Aadam, Demetrios Tzimas, Mihir S Wagh, Peter V Draganov, M D The LA-Ercp Research Group Jeffrey Ponsky, Bruce D Greenwald, Lance T Uradomo, Alyson A McGhan, Shahrad Hakimian, Andrew Ross, Stuart Sherman, Benjamin L Bick, Christopher E Forsmark, Dennis Yang, Anand Gupte, Shailendra Chauhan, Steven J Hughes, Karen Saks, Gennadiy Bakis, Adam W Templeton, Michael Saunders, Alireza Sedarat, John A Evans, Thiruvengadam Muniraj, Timothy B Gardner, Almino C Ramos, Marco Aurelio Santo, Andrew Nett, Gregory A Coté, B Joseph Elmunzer, Kulwinder S Dua, Michael J Nosler, Daniel S Strand, Paul Yeaton, Shivangi Kothari, Asad Ullah, Pushpak Taunk, Patrick Brady, Haim Pinkas, Ashley L Faulx, Haroon Shahid, Jordan Holmes, Davinderbir Pannu, Srinadh Komanduri, Juan Carlos Bucobo, Harry Dhaliwal, Alaa Rostom, Brent W Acker
BACKGROUND AND AIMS: The obesity epidemic has led to increased use of Roux-en-Y gastric bypass (RYGB). These patients have an increased incidence of pancreaticobiliary diseases yet standard ERCP is not possible due to surgically altered gastroduodenal anatomy. Laparoscopic-ERCP (LA-ERCP) has been proposed as an option but supporting data are derived from single center small case-series. Therefore, we conducted a large multicenter study to evaluate the feasibility, safety, and outcomes of LA-ERCP...
November 9, 2017: Gastrointestinal Endoscopy
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