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https://www.readbyqxmd.com/read/28219756/atrial-angioleiomyoma-with-myopericytoma-like-features-a-case-report
#1
Hussein Nassereddine, Aurélie Cazes, Constance Verdonk, Benjamin Assous, Raphael Dautry, Patrick Nataf, Michel Wassef, Lydia Deschamps
A 66-year-old female patient was referred to our hospital for resection of a right atrial mass. Four months earlier, she had suffered an acute cerebrovascular accident due to occlusion of the sylvian segment of the right middle cerebral artery from atheromatous tight stenosis in the right internal carotid artery. Later, investigations with transthoracic and transesophageal echocardiography revealed a 3.4-cm right atrial mass that was resected surgically. Microscopic evaluation revealed a well-circumscribed nodular tumor, located within the interatrial septum, and corresponding to an angioleiomyoma (ALM)...
February 8, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28217430/giant-left-atrial-myxoma-cause-for-position-dependent-nocturnal-dyspnea-and-cardiac-murmur
#2
Julia Hillebrand, Sven Martens, Andreas Hoffmeier
Primary tumors of the heart are rare. The majority of them are benign, the left atrial myxoma being the most frequent one. Clinical appearance varies from unapparent to life-threatening complications such as stroke, acute heart failure, or even sudden death. Diagnosis and consecutive surgical treatment strongly depend on the clinical symptoms, but their extent does not correlate with the risk for serious complications. Therefore, patients with variable clinical presentation can be especially endangered. Consequent diagnostic and immediate operative therapy is essential...
January 2017: Thoracic and Cardiovascular Surgeon Reports
https://www.readbyqxmd.com/read/28202247/radiological-characteristics-of-atrial-myxoma-in-cardiac-computed-tomography
#3
Kawa Haji, Arthur Nasis
BACKGROUND: Although the primary role of Cardiac Computed Tomography (CCT) is assessment of the coronary arteries, the technique also allows detailed examination of cardiac structures and other cardiac pathologies including cardiac myxoma. However, limited data exists regarding the CCT characteristics of cardiac myxoma. OBJECTIVE: To describe the radiological characteristics of a series of cardiac myxomas in CCT. METHODS: We retrospectively identified all patients at our tertiary urban referral centre with cardiac myxoma on CCT over a seven-year period between July 2008 and July 2015...
February 7, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28195879/fibrin-associated-ebv-positive-large-b-cell-lymphoma-an-indolent-neoplasm-with-features-distinct-from-diffuse-large-b-cell-lymphoma-associated-with-chronic-inflammation
#4
Daniel F Boyer, Penelope A McKelvie, Laurence de Leval, Kerstin L Edlefsen, Young-Hyeh Ko, Zachary A Aberman, Alexandra E Kovach, Aneal Masih, Ha T Nishino, Lawrence M Weiss, Alan K Meeker, Valentina Nardi, Maryknoll Palisoc, Lina Shao, Stefania Pittaluga, Judith A Ferry, Nancy Lee Harris, Aliyah R Sohani
Incidental cases of localized fibrin-associated Epstein-Barr virus (EBV)+ large B-cell proliferations have been described at unusual anatomic sites and have been included in the category of diffuse large B-cell lymphoma associated with chronic inflammation (DLBCL-CI) in the WHO Classification. We describe 12 cases and review the literature to define their clinicopathologic spectrum and compare features with typical cases of DLBCL-CI. Median age was 55.5 years with a M:F ratio of 3. In all 12 cases, the lymphoma was an incidental microscopic finding involving atrial myxomas (n=3), thrombi associated with endovascular grafts (n=3), chronic hematomas (n=2), and pseudocysts (n=4)...
March 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28194289/an-interesting-case-of-intramuscular-myxoma-with-scapular-bone-lysis
#5
Jérôme Tirefort, Frank C Kolo, Alexandre Lädermann
Introduction. Intramuscular myxoma is a rare benign primitive tumor of the mesenchyme founded at the skeletal muscle level; it presents itself like an unpainful, slow-growing mass. Myxomas with bone lysis are even more rare; only 7 cases have been reported in the English literature, but never at the shoulder level. Case Presentation. We describe an 83-year-old patient with a growing mass in the deltoid muscle with unique scapular lysis, without any symptom. Magnetic resonance imaging (MRI) and a biopsy were performed and the diagnosis of intramuscular myxoma has been retained...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/28193294/myxoma-of-the-kidney-an-unusual-benign-renal-tumor-a-case-report
#6
Somuah Tenkorang, Youssef Kharbach, Jean-Paul Omana, Boubacar Efared, Soufiane Mellas, Mohammed Fadl Tazi, Mohamed Sekal, Taoufik Harmouch, Abdelhak Khallouk, Jamal Mohammed El Fassi, Jalal Eddine El Ammari, Moulay Hassan Farih
BACKGROUND: Myxomas are rare benign soft tissue tumors. The kidney is an unusual location for this tumor. For this reason, less than 15 cases of renal myxoma have been reported in the English literature. There are no specific clinical and radiological features reported for this tumor that allow a preoperative diagnosis enabling a conservative treatment. CASE PRESENTATION: We report another case of renal myxoma found in a 50-year-old Moroccan woman who presented with a right dull flank pain...
February 14, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28187355/multimodality-imaging-of-benign-or-malignant-tumors-in-the-vena-cava-and-its-main-branches
#7
REVIEW
Honglian Wu, Huawei Zhang, Shumin Wang, Xuejun Wu, Dianning Dong, Changhu Liang
Tumors arising from or secondarily involving the vena cava (VC) are broad-spectrum diseases, ranging from benign to malignant. The benign tumors include myxoma, leiomyomatosis and leiomyoma. The primary malignant tumors of the VC are rare, and of these rare entities, leiomyosarcoma is the most frequently encountered. The direct extension of a tumor arising from an adjacent organ such as hepatocellular carcinoma or renal cell carcinoma is more common than primary malignant tumor in the inferior VC. In this article, the authors review the spectrum of VC pathologic processes and the relevant findings from magnetic resonance imaging, ultrasonography, and computed tomography...
October 19, 2016: Clinical Imaging
https://www.readbyqxmd.com/read/28183439/cardiac-myxoma-the-great-mimicker
#8
Abdallah El Sabbagh, Mohammed A Al-Hijji, Jeremy J Thaden, Sorin V Pislaru, Cristina Pislaru, Patricia A Pellikka, Adelaide M Arruda-Olson, Martha Grogan, Kevin L Greason, Joseph J Maleszewski, Kyle W Klarich, Vuyisile T Nkomo
No abstract text is available yet for this article.
February 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28160572/karyotyping-and-analysis-of-gnas-locus-in-intramuscular-myxomas
#9
Ioannis Panagopoulos, Ludmila Gorunova, Ingvild Lobmaier, Bodil Bjerkehagen, Sverre Heim
Intramuscular myxoma is a benign soft tissue tumor about which very limited genetic information exists. We studied 68 intramuscular myxomas by means of chromosome banding analysis finding abnormal karyotypes in 21 of them. The most clearly nonrandom involvement was of chromosome 8 which was found gained in seven tumors (+8 was the sole change in five myxomas) and structurally rearranged in another two. Since mutation of the gene GNAS (20q13) has been implicated in the pathogenesis of both solitary and hereditary multiple myxomas, we assessed the transcription and mutation status of this gene in five tumors from which we had suitable RNA...
February 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28157624/an-interaction-domain-in-human-samd9-is-essential-for-myxoma-virus-host-range-determinant-m062-antagonism-of-host-anti-viral-function
#10
Bernice Nounamo, Yibo Li, Peter O'Byrne, Aoife M Kearney, Amir Khan, Jia Liu
In humans, deleterious mutations in the sterile α motif domain protein 9 (SAMD9) gene are associated with cancer, inflammation, weakening of the immune response, and developmental arrest. However, the biological function of SAMD9 and its sequence-structure relationships remain to be characterized. Previously, we found that an essential host range factor, M062 protein from myxoma virus (MYXV), antagonized the function of human SAMD9. In this study, we examine the interaction between M062 and human SAMD9 to identify regions that are critical to SAMD9 function...
January 31, 2017: Virology
https://www.readbyqxmd.com/read/28157174/myxoma%C3%A2-virus%C3%A2-dsrna%C3%A2-binding%C3%A2-protein%C3%A2-m029%C3%A2-inhibits%C3%A2-the%C3%A2-type%C3%A2-i%C3%A2-ifn-induced%C3%A2-antiviral%C3%A2-state%C3%A2-in%C3%A2-a%C3%A2-highly%C3%A2-species-specific%C3%A2-fashion
#11
Masmudur M Rahman, Grant McFadden
Myxoma virus (MYXV) is Leporipoxvirus that possesses a specific rabbit-restricted host tropism but exhibits a much broader  cellular host range in cultured cells. MYXV is able to efficiently  block all aspects of the type I interferon (IFN)-induced  antiviral  state  in rabbit cells, partially in  human  cells  and  very  poorly  in  mouse  cells.  The mechanism(s) of this species-specific inhibition of  type I IFN-induced antiviral state is not well understood...
February 2, 2017: Viruses
https://www.readbyqxmd.com/read/28153133/odontogenic-cysts-and-neoplasms
#12
REVIEW
Elizabeth Ann Bilodeau, Bobby M Collins
This article reviews a myriad of common and uncommon odontogenic cysts and tumors. The clinical presentation, gross and microscopic features, differential diagnosis, prognosis, and diagnostic pitfalls are addressed for inflammatory cysts (periapical cyst, mandibular infected buccal cyst/paradental cyst), developmental cysts (dentigerous, lateral periodontal, glandular odontogenic, orthokeratinized odontogenic cyst), benign tumors (keratocystic odontogenic tumor, ameloblastoma, adenomatoid odontogenic tumor, calcifying epithelial odontogenic tumor, ameloblastic fibroma and fibroodontoma, odontoma, squamous odontogenic tumor, calcifying cystic odontogenic tumor, primordial odontogenic tumor, central odontogenic fibroma, and odontogenic myxomas), and malignant tumors (clear cell odontogenic carcinoma, ameloblastic carcinoma, ameloblastic fibrosarcoma)...
March 2017: Surgical Pathology Clinics
https://www.readbyqxmd.com/read/28151506/-myocardial-infarction-as-the-first-manifestation-of-an-atrial-myxoma-the-bomb-in-the-heart-case-report-and-literature-review
#13
Pierpaolo Cannarile, Alberto Cresti, Stefania Stefanelli, Paolo Calabria, Paola Pasqualini, Marco Solinas, Ugo Limbruno
Atrial myxoma is a cardiac tumor often histologically benign but very insidious for its mechanical complications. Among these, myocardial infarction can be an expression of coronary embolism. Imaging techniques are essential for the diagnosis and the therapeutic steps. We describe the clinical case of a 52-year-old woman with acute myocardial infarction and normal coronary arteries with left atrial myxoma. We conducted a review of published case reports over the last 45 years on the rare association between atrial myxoma and acute myocardial infarction, to obtain pathogenic and epidemiological information from the real world...
December 2016: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/28151505/-a-late-diagnosis-of-left-atrial-myxoma-how-to-gain-time
#14
Ferdinando Maria Massari, Tatiana Tonella, Giuseppe Pomè, Alessandra Di Mauro, Claudio Clemente, Federico Lombardi
A 56-year-old man presented to the Outpatient Cardiology Unit for dyspnea that had been lasting 6 months and an occasional episode of cold perspiration on climbing a flight of stairs. In the suspicion of coronary artery disease, he was prescribed a complete blood panel, an echocardiogram and a treadmill stress test. The echocardiogram, performed as late as 78 days after the first evaluation and only by chance scheduled 2 days before the stress test, enabled a diagnosis of left atrial myxoma for which the patient successfully underwent cardiac surgery...
December 2016: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/28138817/incremental-value-of-cardiac-magnetic-resonance-for-the-evaluation-of-cardiac-tumors-in-adults-experience-of-a-high-volume-tertiary-cardiology-centre
#15
Sorin Giusca, Derliz Mereles, Andreas Ochs, Sebastian Buss, Florian André, Sebastian Seitz, Johannes Riffel, Philipp Fortner, Mindaugas Andrulis, Stefan Schönland, Hugo A Katus, Grigorios Korosoglou
To assess the value of cardiac magnetic resonance imaging (CMR) in evaluating cardiac tumours in a tertiary cardiology centre. Between 2004 and 2014, 125 patients (pts.) from a total of 17000 who received a CMR examination in our institution were referred with the suspicion of cardiac tumours. A dedicated protocol was used that included standard cine SSFP acquisitions as well as tissue characterization using T1 and T2 black-blood (T1 BB and T2 BB respectively) with and without fat suppression, perfusion of the structure and late gadolinium enhancement...
January 30, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28127217/extracardiac-manifestations-of-atrial-myxomas
#16
REVIEW
Braghadheeswar Thyagarajan, Monisha Priyadarshini Kumar, Shil Patel, Abhinav Agrawal
Primary cardiac tumors are extremely rare and constitute only about 5% of all cardiac tumors. Cardiac myxomas are noncancerous primary tumors of the heart and constitute about of 50% of all primary heart tumors. Left-sided atrial myxomas are more common than right-sided atrial myxomas. Atrial myxomas can lead to a triad of complications. The most common symptoms are associated with obstruction due to the size and location of the tumor. The next most common symptoms are associated with pulmonary and systemic embolization...
January 2017: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/28118960/myxoma-originating-from-the-anterior-mitral-valve-leaflet-in-a-young-patient-with-neurological-manifestations
#17
Małgorzata Zachura, Jacek Kurzwski, Antoinette Urbaniak, Łukasz Piątek, Marianna Janion
No abstract text is available yet for this article.
December 23, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28096843/left-atrial-myxoma-in-a%C3%A2-patient-with-a%C3%A2-biventricular-pacemaker
#18
Brygida Przywara-Chowaniec, Łukasz Czarnecki, Ewa Nowalny-Kozielska, Maciej Gawlikowski, Mariusz Opara, Agata Puzio, Damian Kawecki, Bartosz Wesołowski
Myxomas make up about 50% of benign cardiac neoplasms. The most common location is within the left atrium. At the initial stage they do not exhibit any specific clinical symptoms, so they are often diagnosed by accident or during examinations recommended for other reasons. Here we present a case of left atrium myxoma in a patient (a man, age 68 years) with a dual chamber pacemaker. The myxoma did not reveal any clinical symptoms and was discovered in echocardiography during routine diagnostic examination preceding pacemaker implantation...
December 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28096835/left-atrial-appendage-mass-is-it-always-a-thrombus
#19
Hikmet Sahratov, Adem Guler, Mustafa Kurkluoglu, Fahri Gurkan Yesil, Murat Tavlasoglu, Faruk Cingoz
Myxoma is the most common benign tumor of the heart, but it is very rare for it to originate from the left atrial appendage. Distinguishing between a mass, a thrombus, and a tumor in the body of the left atrium with preoperative transthoracic or transesophageal echocardiography is very difficult, even more so in patients with mitral valve disease and chronic atrial fibrillation. A 50-year-old male patient was admitted for surgery with the diagnosis of mitral stenosis and chronic atrial fibrillation. Transesophageal echocardiography demonstrated a mass attached to the wall of the left atrial appendage...
December 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28092256/-resection-of-intracardiac-myxoma-case-report
#20
Víctor Manuel Carmona-Delgado, Angélica María Deloya-Maldonado, María Lourdes Carranza-Bernal, Arturo Hinojosa-Pérez, Leobardo Farías-Mayene
Myxomas are the most common benign cardiac tumors, which are considered emergency surgery. The resection should not be delayed because 8-9% of affected patients may die due to intracardiac blood flow obstruction. We presente a clinical case of a 47 year old female, history of dyslipidemia. Disease starts with retrosternal oppression feeling, dyspnea on moderate exercise, dizziness, pain in joints hands. Arrhytmic heart sounds, diastolic mitral murmur II/IV, breth sounds present, no lymph. Laboratory: hemoglobin 11...
January 2017: Revista Médica del Instituto Mexicano del Seguro Social
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