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https://www.readbyqxmd.com/read/29161691/failure-to-thrive-in-the-context-of-carney-complex
#1
Amit Tirosh, Adi Auerbach, Belen Bonella, Phaedon D Zavras, Elena Belyavskaya, Charalampos Lyssikatos, Karen Meir, Ram Weiss, Hagit Daum, Maya B Lodish, David Gillis, Constantine A Stratakis
BACKGROUND/AIMS: Carney complex (CNC) is a rare syndrome associated with multiple tumors and several other unique manifestations. We describe the clinical, genetic, and laboratory findings in a cohort of patients with CNC and failure to thrive (FTT). METHODS: A retrospective case series of pediatric patients with CNC presenting with FTT. RESULTS: We describe a patient with infantile Cushing syndrome (CS) who presented with severe FTT and liver disease; the patient was subsequently diagnosed with CNC...
November 21, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/29153872/malignant-lymphoma-arising-in-cardiac-myxoma-presenting-with-peripheral-arterial-emboli
#2
Cheol Keun Park, Yoon Ah Cho, Moonsik Kim, Hyo Sup Shim
Composite tumors of cardiac myxoma and malignant lymphoma are extremely rare, with 11 of such cases reported in the literature. A 44-year-old man presented to us with abrupt right lower leg pain. A computed tomography angiogram revealed segmental obstruction of the right common femoral artery, and embolectomy was performed. The embolectomy specimen contained several clusters of degenerated round/oval atypical cells in the fibrinous or myxoid background. Immunohistochemical examination revealed that these atypical cells were negative for cytokeratin and non-specifically expressed CD45...
October 14, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/29146961/identification-of-host-dead-box-rna-helicases-that-regulate-cellular-tropism-of-oncolytic-myxoma-virus-in-human-cancer-cells
#3
Masmudur M Rahman, Eugenie Bagdassarian, Mohamed A M Ali, Grant McFadden
Myxoma virus (MYXV), a Leporipoxvirus, is being developed as an oncolytic virotherapeutic for the treatment of a variety of human cancers. MYXV tropism for human cancer cells is largely mediated by intracellular signaling networks that regulate viral replication or innate antiviral response pathways. Thus, MYXV is fully or partially permissive for the majority of human cancer cells that harbor defects in antiviral signaling, but a minority are nonpermissive because the virus infection aborts before its completion...
November 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29145790/innate-immunity-in-cardiac-myxomas-and-its-pathological-and-clinical-correlations
#4
Anna Di Vito, Gianluca Santise, Chiara Mignogna, Eusebio Chiefari, Gabriella Cardillo, Ivan Presta, Franco Arturi, Natalia Malara, Francesco Brunetti, Annalidia Donato, Domenico Maisano, Stefania Leonetti, Daniele Maselli, Tullio Barni, Giuseppe Donato
Cardiac myxomas are the most common benign cardiac tumor. We investigated the immunohistochemical properties of 11 surgically excised cardiac myxomas, in order to analyze the correlation between macrophages and mast cell populations and clinical parameters. CD68(+)/CD163(-)/iNOS(-) (M0) cells represent the most abundant macrophage phenotype; however, CD68(+)/CD163(+) cells (M2) were also frequent. CD68(+)/iNOS(+) (M1) elements were rare. Mast cells, defined as a population of c-kit (CD117)(+) and/or tryptase(+) cells were also detected...
January 1, 2017: Innate Immunity
https://www.readbyqxmd.com/read/29141631/detection-of-rabbit-haemorrhagic-disease-virus-2-during-the-wild-rabbit-oryctolagus-cuniculus-eradication-from-the-berlengas-archipelago-portugal
#5
F A Abade Dos Santos, C Carvalho, Oliveira Nuno, J J Correia, M Henriques, M C Peleteiro, M Fevereiro, M D Duarte
BACKGROUND: In the regular wildlife monitoring action carried out in the summer of the past few years at the Berlenga Island, wild rabbits (Oryctolagus cuniculus) have been repeatedly found dead. However, the origin of those deaths was never investigated. Our aim was to investigate the cause of death of 11 rabbits collected between April and May 2016. RESULTS: While screening samples from rabbit carcasses for the major viral rabbit pathogens, five tested positive to RHDV2 but all were negative for RHDV and myxoma virus (MYXV)...
November 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29123666/multi-modality-imaging-of-a-left-atrial-myxoma
#6
Hae Won Jung, Joon Hyung Doh, Woo-Ik Chang
Objectives: Although echocardiography has traditionally been used to diagnose myxoma, invasive or non-invasive coronary angiography can be useful diagnostic tool before surgery. Methods: We present a case of an angiographically detected left atrial myxoma feeding from the left circumflex coronary artery. Results: The patient underwent open-heart surgery to remove the left atrial myxoma. After ligation of feeding artery, the mass was successfully excised...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/29118888/a-rare-cause-of-dyspnea-undifferentiated-pleomorphic-sarcoma-in-the-left-atrium
#7
Martin A Munin, Maria Silvia Goerner, Ignacio Raggio, Jorge Wisner, Alejandro Tettamanzi, Jose Godia, Maria Paula Penaloza, Javier Guetta
Primary cardiac tumors are a rare entity. The presence of a mass in the left atrium suggests myxoma as a first differential diagnosis. Here we present a rare case of a woman with exertional dyspnea with a large tumor in the left atrium. The patient was extensively studied with echocardiography, cardiac MRI, coronary angiography and computed tomography. Extracardiac neoplastic involvement was ruled out. The patient underwent surgery, the mass was removed, and the final diagnosis was an undifferentiated pleomorphic sarcoma...
October 2017: Cardiology Research
https://www.readbyqxmd.com/read/29115102/intramuscular-myxoma-of-the-cervical-muscles-with-gnas-mutation
#8
Giulia Pilloni, Marco Ajello, Antonio Melcarne, Nicola Marengo, Francesco Zenga, Diego Garbossa, Alessandro Ducati, Fulvio Tartara
No abstract text is available yet for this article.
November 7, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29109321/epidemiological-and-clinicopathological-analysis-of-92-odontogenic-tumors-a-5-year-retrospective-study
#9
Ipsita Sharma, Deepa Venkatesh, Geetanjali Bawa, Syed Vaseemuddin, Amit Joseph, Jimmy K Sangtani
INTRODUCTION: Odontogenic tumors (OTs) are a heterogeneous group of lesions that are derived from odontogenic apparatus comprised of odontogenic epithelium, ectomesenchyme, and/ or mesenchymal elements. The OTs show marked geographical variation. This study was conducted to analyze the epidemiology and clinicopathological presentation of OTs based on age, sex, and site. MATERIALS AND METHODS: This study was conducted in Department of Oral Pathology and Microbiology...
November 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29100540/isolated-right-ventricular-thrombus-in-an-adult-patient-with-nephrotic-syndrome-a-case-report
#10
Severin Lempp, Vedat Schwenger
BACKGROUND: Venous thrombosis in nephrotic syndrome is a well-described phenomenon. We report a case of an adult patient with an isolated thrombus in the right ventricle due to nephrotic syndrome, which was initially suspected to be a myxoma. CASE PRESENTATION: A 28-year-old white woman presented to our emergency department with signs of fluid overload. On further evaluation, a right ventricular mass was detected, which was resected and was found to be a thrombus...
November 4, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29082773/size-distribution-and-clinico-radiological-signs-of-aggressiveness-in-odontogenic-myxoma-three-dimensional-analysis-and-systematic-review
#11
Martin Kauke, Ali-Farid Safi, Matthias Kreppel, Andrea Grandoch, Hans-Joachim Nickenig, Joachim E Zöller, Timo Dreiseidler
OBJECTIVES: Therapeutic assessment of odontogenic myxoma (OM) is poorly standardized. Unidimensional size criteria have shown to be unreliable in therapeutic decision-making. We evaluate the size distribution of OM and scan for associated clinico-radiological signs of aggressiveness. Additionally, we evaluate three-dimensional size delineation of OM, aiming to improve future therapeutic assessment of this destructive neoplasm. METHODS: Primarily, we reviewed the database "PubMed" for data concerning the size of OMs as radiologically determined...
October 30, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/29062385/central-nervous-system-and-limb-embolism-concurrence-due-to-atrial-myxoma-a-case-report%C3%A2
#12
Javad Salimi, Khosro Najari, Pezhman Farshidmehr, Roja Toosi, Batool Naghavi, Tayeb Ramim
Cardiac myxomas are the most common cardiac tumors with diverse nonspecific clinical manifestations. A 78-year-old man presented to the emergency department with complaints of pain and coldness of the left lower extremity. The left femoral artery pulse was detected, while the pulses of the left popliteal, dorsalis pedis, and posterior tibialis arteries were absent. No blood inflow was detected in the superficial and deep femoral, popliteal, and anterior and posterior tibialis arteries. Thrombectomy was performed, and a fatty-like mass from the bifurcation of the common femoral artery and a thrombotic mass from the proximal portion of the superficial and deep femoral arteries were removed...
July 2017: Journal of Tehran Heart Center
https://www.readbyqxmd.com/read/29048497/unusual-atrial-myxoma-with-neovascularization-associated-with-fistula-to-right-atrium
#13
Anurut Huntrakul, Jule Numchaisiri, Wacin Buddhari, Pairoj Chattranukulchai
No abstract text is available yet for this article.
October 14, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29028515/post-biopsy-mri-changes-in-the-size-and-enhancement-of-intramuscular-myxomas-a-report-of-two-cases
#14
Wilbur Wang, Edward Smitaman, Wesley Rubenstein, Tudor Hughes, Brady K Huang
Intramuscular myxomas are benign soft-tissue tumors, characterized by bland spindle-shaped cells and fibroblasts within an abundant mucoid matrix on histologic examination. Classically, these are slowly enlarging masses which may occasionally cause pain, paresthesia, and muscle weakness secondary to mass effect. We present an interesting phenomenon of two histologically confirmed cases of intramuscular myxomas that exhibited size and enhancement changes on follow-up imaging after image-guided biopsy. To our knowledge, this is the first report to describe size and enhancement changes of intramuscular myxomas after biopsy...
September 28, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29022244/systemic-embolism-from-bilateral-atrial-myxomas
#15
Wei-Chieh Lee, Huang-Chung Chen, Sarah Chua
No abstract text is available yet for this article.
October 11, 2017: Journal of Echocardiography
https://www.readbyqxmd.com/read/28994684/atrial-myxomas-causing-severe-left-and-right-ventricular-dysfunction
#16
Aanchal Dixit, Prabhat Tewari, Rashmi Soori, Surendra Kumar Agarwal
Myxomas are the most common cardiac tumors, accounting for about 50% of benign primary cardiac tumors, with the majority located in the left atrium, and 80% of which originate in the interatrial septum. We report two cases with severe cachexia, neurological sequelae, and severe biventricle dysfunction secondary to atrial myxomas with marked early improvement after tumor excision.
October 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28990955/case-image-acute-coronary-syndrome-accompanying-transient-ischemic-attack-an-unusual-presentation-of-myxoma
#17
Abdulkadir Uslu, Cem Doğan
No abstract text is available yet for this article.
October 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28985009/odontogenic-myxoma-a-63-year-retrospective-multicenter-study-of-85-cases-in-a-brazil-population-and-a-review-of-999-cases-from-literature
#18
Ana Carolina Uchoa Vasconcelos, Felipe Martins Silveira, Ana Paula Neutzling Gomes, Sandra Beatriz Chaves Tarquinio, Ana Paula Veras Sobral, José Alcides Almeida de Arruda, Leorik Pereira da Silva, Marcia Maria Fonseca da Silveira, Larissa Ferreira Barbosa, Camila de Nazaré Alves de Oliveira Kato, Filipe Jaeger, Tarcília Aparecida da Silva, Ricardo Alves Mesquita
BACKGROUND: Odontogenic myxoma (OM) is an uncommon neoplasm of the jaws. Considering the importance of defining the relative incidence and demographic profile of these lesions in South America, the aim of this study was to analyze the clinical and imagiological features of OM from three South American oral pathology services and to discuss these findings in light of the literature. METHODS: Data regarding age, gender, anatomic site, and imagiological features from 85 cases of OM were collected...
October 6, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28984035/carney-complex-revealed-by-a-cerebellar-ischaemic-stroke-in-a-6-year-old-girl
#19
LETTER
M Acquitter, V Laparra, E Brenaut, S Peudenier, R Teissier, E Clauser, L Misery, C Abasq-Thomas
No abstract text is available yet for this article.
October 6, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28980343/outcomes-following-embolization-in-patients-with-cardiac-myxoma
#20
Kamil Boyacıoğlu, Mehmet Kalender, Arzu A Dönmez, Burcin Çayhan, Mehmet A Tuncer
BACKGROUND: Cardiac myxomas are the most frequent primary benign intracardiac tumors. We reviewed our 27-year experience to evaluate factors associated with an embolism in patients with cardiac myxomas and their long-term outcomes. METHODS: A retrospective review identified 99 patients with cardiac myxomas between 1985 and 2012. Tumors were divided into two groups based on their gross external features. Tumors with a smooth regular border and a solid consistency were classified as solid; papillary myxomas were characterized by an irregular and gelatinous exterior with friable, soft consistency...
October 2017: Journal of Cardiac Surgery
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