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Fluorescein angiography

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https://www.readbyqxmd.com/read/28550346/differential-microvascular-assessment-of-retinal-vein-occlusion-with-coherence-tomography-angiography-and-fluorescein-angiography-a-blinded-comparative-study
#1
Chung Yee Chung, Heather Hoi Yau Tang, Siu Hung Li, Kenneth Kai Wang Li
PURPOSE: To compare the imaging of retinal vein occlusion (RVO) with optical coherence tomography angiography (OCTA) and fluorescein angiography (FA) and evaluate their roles in clinical management. METHODS: RVO patients who underwent imaging with both FA and OCTA from 1 June 2015-31 December 2015 were enrolled. An independent retinal specialist blinded from patient identity assessed the FA and OCTA reports. The pixel counting technique was used for FAZ size measurement...
May 26, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28547533/sensitivity-and-specificity-of-optical-coherence-tomography-angiography-oct-a-for-detection-of-choroidal-neovascularization-in-real-life-practice-and-varying-retinal-expertise-level
#2
Vaël Souedan, Eric H Souied, Violaine Caillaux, Alexandra Miere, Ala El Ameen, Rocio Blanco-Garavito
PURPOSE: To evaluate the diagnostic accuracy of OCT angiography (OCT-A) detecting or predicting choroidal neovascularization (CNV), by ophthalmologists of disparate degrees of skills in retinal diseases, using spectral domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA) as a standard reference. METHODS: Retrospective observational case series. Patient presenting maculopathy and complete imaging were included. FA, SD-OCT, OCT-A and FA coupled to SD-OCT images were graded independently for presence or absence of CNV by ophthalmologists with varying expertise levels...
May 25, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28546934/foveal-thickness-reduction-after-anti-vascular-endothelial-growth-factor-treatment-in-chronic-diabetic-macular-edema
#3
Gabriel Willmann, Antonio Brunno Nepomuceno, Katharina Messias, Leticia Barroso, Ingrid U Scott, André Messias, Rodrigo Jorge
AIM: To report foveal thickness reduction in eyes with resolution of macular edema and recovery of a foveal depression after one-year of anti-vascular endothelial growth factor (anti-VEGF) therapy for center-involving diabetic macular edema (DME). METHODS: Foveal thickness was assessed with optical coherence tomography to determine the central subfield foveal thickness (CSFT) and macular volume in 42 eyes with DME (CSFT>275 µm). Evaluations also included measurement of best-corrected visual acuity (BCVA), and were performed at baseline, and upon foveal depression recovery achieved after 12 monthly intravitreal injections of either 1...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28541266/retinochoroidal-anastomosis-associated-with-enhanced-s-cone-syndrome
#4
Jennyfer Zerbib, Rocio Blanco Garavito, Sylvie Gerber, Hassiba Oubraham, Anne Sikorav, Isabelle Audo, Josseline Kaplan, Jean-Michel Rozet, Eric H Souied
PURPOSE: To describe the phenotype and genotype of a 10-year-old boy affected with enhanced S-cone syndrome associated with neovascularization. METHODS: Fundus autofluorescence, fluorescein angiography, indocyanine green angiography, spectral domain optical coherence tomography, full-field electroretinogram and NR2E3 molecular testing were performed. RESULTS: Best-corrected visual acuity was measured as 20/32, right eye and 20/20, left eye...
May 22, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28540884/effect-of-fluorescein-angiography-on-renal-functions-in-type-2-diabetes-patients-a-pilot-study
#5
Waleed H Almalki, Ashraf Nabiel Abdalla, Ahmed F Elkeraie, Ahmed M Abdelhadi, Mahmoud Elrggal, Mohamed E Elrggal
Fluorescein angiography (FA) is an important tool for the diagnosis and management of diabetic retinopathy. However, the safety of fluorescein sodium on renal functions is not fully understood. One hundred type 2 diabetes patients, within the Ophthalmology Outpatient Clinic at Alexandria Main University Hospital, Egypt, were enrolled in this prospective observational study to determine the safety of FA on renal function. Serum creatinine and cystatin C were measured pre- and 2 days post-FA. Urinary neutrophil gelatinase-associated lipocalin (uNGAL) was measured pre- and 4 hours post-FA...
May 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28536763/acute-visual-loss-after-botulinum-toxin-a-injection-in-the-masseter-muscle
#6
Bo Young Chun, Su Yeon Kim
PURPOSE: Acute visual loss after facial injection of cosmetic materials is rarely reported. In this study, we report one patient who developed acute visual loss after an injection of botulinum toxin A for esthetic purposes. METHODS: A 43-year-old Korean woman presented with a decrease in visual acuity to 20/800 after an injection of botulinum toxin A in the masseter muscle. The visual field testing showed an inferior altitudinal defect, and fluorescein angiography revealed a delayed arm-retinal circulation time...
May 23, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28525681/unveiling-idiopathic-macular-telangiectasia-clinical-applications-of-optical-coherence-tomography-angiography
#7
Marco A Gonzalez, Diana Shechtman, Jay M Haynie, Leo Semes
PURPOSE: Idiopathic macular telangiectasia type 2 (IMT2) is a bilateral acquired maculopathy, with a spectrum of clinical presentations associated with inner retinal telangiectatic vascular anomalies. Cases often are underdiagnosed or misdiagnosed. Current diagnostic modalities such as spectral-domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA) are valuable to the understanding of the clinicopathology. More recently, optical coherence tomography angiography (OCTA), as an emerging noninvasive technology, has been shown to be particularly useful in the assessment and management of IMT2...
May 19, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28524835/collapsin-response-mediator-protein-2-induced-retinal-ischemic-injury-in-a-novel-mice-model-of-ocular-ischemia-syndrome
#8
Yu Wang, Xiao-Lei Wang, Guo-Li Xie, Hong-Yang Li, Yan-Ling Wang
BACKGROUND: Collapsin response mediator protein-2 (CRMP2) has been shown to be involved in ischemia/hypoxia (IH) injury. We determined whether CRMP2 modulates ischemic injury in the retinal of Ocular ischemic syndrome (OIS). This study was to explore the molecular mechanisms underlying OIS in a novel mice model. METHODS: Experiments were performed on adult male C57/BL6 mice that received bilateral internal carotid arteries ligation for 1, 2, or 4 weeks. The mice received injection of calpeptin group before occlusion for 4 weeks or not...
June 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28524148/-atypical-clinical-case-of-solar-retinopathy
#9
N V Pomytkina, A L Zhirov, T L Sorokin
The paper presents an atypical case of solar retinopathy after short-term exposure to reflected focused sunbeams. An ophthalmoscopic peculiarity was the presence of intraretinal hemorrhage. The basis for establishing the diagnosis were spectral optical coherence tomography and fluorescein angiography findings.
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28524134/-oct-morphometric-and-angiographic-parallels-between-different-variants-of-central-serous-chorioretinopathy
#10
I E Panova, T B Shaimov, V A Shaimova
Central serous chorioretinopathy (CSCR) is a frequent cause of vision deterioration. Often it is associated with type 1 neovascularization under the pigment retinal epithelium (RPE). Optical coherence tomography angiography (OCT-angiography) enables non-invasive and contrast-free detection of neovessels in any retinal layer, which makes the method appropriate for diagnostics in CSCR. AIM: to investigate OCT-morphometric and angiographic parallels between different CSCR courses. MATERIAL AND METHODS: The study included 37 patients with CSCR...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28523457/retinal-pigmentary-changes-in-chronic-uveitis-mimicking-retinitis-pigmentosa
#11
D Damla Sevgi, Samaneh Davoudi, Jason Comander, Lucia Sobrin
PURPOSE: To present retinal pigmentary changes mimicking retinitis pigmentosa (RP) as a finding of advanced uveitis. METHODS: We retrospectively reviewed charts of patients without a family history of inherited retinal degenerations who presented with retinal pigment changes and signs of past or present intraocular inflammation. Comprehensive eye examination including best-corrected visual acuity, slit-lamp examination and dilated fundus examination was performed on all patients in addition to color fundus photography, optical coherence tomography, fluorescein angiography (FA), and full-field electroretinogram testing...
May 18, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28520642/inflammatory-choroidal-neovascular-membrane-long-term-visual-and-anatomical-outcomes-after-intravitreal-anti-vascular-endothelial-growth-factor-therapy
#12
Palmeera Dʼsouza, Ratnesh Ranjan, Upendra Babu, Anuradha V Kanakath, Veerappan R Saravanan
PURPOSE: To assess the long-term visual and anatomical outcomes after intravitreal anti-vascular endothelial growth factor therapy for inflammatory choroidal neovascular membrane (CNVM). METHODS: Retrospective case series of 15 consecutive cases of newly diagnosed inflammatory CNVM who were treated with intravitreal bevacizumab or ranibizumab injections. RESULTS: The study included 8 women and 7 men with mean age at presentation with CNVM of 40...
May 16, 2017: Retina
https://www.readbyqxmd.com/read/28520638/effects-of-intravitreal-ranibizumab-and-bevacizumab-on-the-retinal-vessel-size-in-diabetic-macular-edema
#13
Muhammed Mustafa Kurt, Osman Çekiç, Çetin Akpolat, Mustafa Elçioglu
PURPOSE: The goal of this study was to assess the effects of a single injection of intravitreal ranibizumab (RAN) or bevacizumab (BEV) on the retinal vessel size in eyes with diabetic macular edema. MATERIALS AND METHODS: In total, 32 patients were enrolled in the RAN group, and 30 patients were included in BEV group. Each of these groups was also subdivided into two others groups: a study group and a control group. The study groups were composed of the injected eyes, whereas the noninjected fellow eyes served as the control groups...
May 16, 2017: Retina
https://www.readbyqxmd.com/read/28512425/long-term-follow-up-of-polypoidal-choroidal-vasculopathy-secondary-to-angioid-streaks-treated-by-intravitreal-aflibercept-and-ranibizumab
#14
James G Wong, Katherine Yu Qian
PURPOSE: Angioid streaks (AS) are dehiscences in Bruch's membrane that may be idiopathic or associated with numerous systemic illnesses. Polypoidal choroidal vasculopathy (PCV) is an underdiagnosed exudative chorioretinopathy often characterised by serosanguineous detachments of the pigmented epithelium. The use of the anti-VEGF agents ranibizumab and aflibercept in the management of PCV secondary to AS has not been previously documented. We report 3 patients with active PCV secondary to AS, 1 of which had a family history of PCV secondary to AS, not previously reported in the literature...
January 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28506260/atypical-retinal-pigment-epithelial-defects-with-retained-photoreceptor-layers-a-so-far-disregarded-finding-in-age-related-macular-degeneration
#15
Helena Giannakaki-Zimmermann, Giuseppe Querques, Inger Christine Munch, Daraius Shroff, David Sarraf, Xuejing Chen, Eduardo Cunha-Souza, Sarah Mrejen, Vittorio Capuano, Murilo W Rodrigues, Charu Gupta, Andreas Ebneter, Martin S Zinkernagel, Marion R Munk
BACKGROUND: To report patients with age-related macular degeneration and atypical central retinal pigment epithelium (RPE) defects not attributable to geographic atrophy (GA) or RPE-tears with overlying preserved photoreceptor layers. METHODS: Multimodal imaging case-series evaluating the course of atypical RPE- defects in patients with AMD using Color fundus images, Optical coherence tomography (OCT), OCT-Angiography, fundus autofluorescence (FAF) and fluorescein-angiography (FA)...
May 15, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28505012/correlation-of-clinical-and-structural-progression-with-visual-acuity-loss-in-macular-telangiectasia-type-2-mactel-project-report-no-6-the-mactel-research-group
#16
Tunde Peto, Tjebo F C Heeren, Traci E Clemons, Ferenc B Sallo, Irene Leung, Emily Y Chew, Alan C Bird
PURPOSE: To evaluate progression of macular telangiectasia Type 2 lesions and their correlation with visual acuity. METHODS: An international multicenter prospective study with annual examinations including best-corrected visual acuity (BCVA), fundus photography, fluorescein angiography, and optical coherence tomography images graded centrally. Mixed models were used to estimate progression rates, and a generalized linear model to compute the relative risk of BCVA loss, loss of ellipsoid zone (EZ) reflectivity, development of pigment plaques, or neovascularization...
May 11, 2017: Retina
https://www.readbyqxmd.com/read/28500127/the-efficacy-of-hyperbaric-oxygen-therapy-in-the-treatment-of-central-retinal-artery-occlusion
#17
Andreia Soares, Nuno L Gomes, Luís Mendonça, Carla Ferreira
Central retinal artery occlusion (CRAO) is an ophthalmological emergency. Various treatment modalities have been tried, but none have shown to alter natural history of the disease. Hyperoxia can restore retinal oxygenation, and favourable results were obtained with hyperbaric oxygen therapy (HBOT). We report two patients with sudden visual loss due to CRAO treated with HBOT. Case 1: a 61-year-old female, presented with CRAO in her left eye(OS). She was submitted to eight sessions of HBOT(2.4atmosphere absolute (ATA))...
May 12, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28497336/the-overlapping-spectrum-of-flat-irregular-pigment-epithelial-detachment-investigated-by-optical-coherence-tomography-angiography
#18
Francesco Pichi, Mariachiara Morara, Chiara Veronese, Antonio P Ciardella
PURPOSE: To describe the OCT angiography characteristics of flat irregular pigment epithelial detachments (PEDs), an overlapping tomographic feature of various macular disorders. METHODS: Consecutive patients with a dimpled retinal pigment epithelium profile on OCT, referred for a second opinion, were enrolled. Fluorescein (FA) and indocyanine green angiography (ICGA) were performed in all patients and compared to previous examinations, when available. In all patients, enhanced depth imaging-OCT and OCT angiography were performed upon referral and at subsequent follow-ups...
May 11, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28496373/multimodal-images-of-chronic-branch-retinal-vein-occlusion
#19
Stephen G Schwartz, Armando Monroig, Harry W Flynn
Two illustrative cases of chronic branch retinal vein occlusion are presented with multimodal imaging, including commercially available optical coherence tomography angiography. In these two patients, retinal ischemia and collateral vessels were well imaged without the need to use traditional fluorescein angiography. Optical coherence tomography angiography provides useful information for the diagnosis and management of patients with branch retinal vein occlusion and other retinal vascular diseases.
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/28494562/-intraoperative-risk-factors-associated-with-visual-acuity-outcomes-of-pars-plana-vitrectomy-in-idiopathic-epiretinal-membrane
#20
H H Li, X Liao, C L Xie, X R Gao, H Wang, F Wang
Objective: To evaluate intraoperative risk factors related to the postoperative visual acuity in idiopathic epiretinal membrane (IERM) . Methods: According to the well-established study criterion, a retrospective observational study was carried out on 37 eyes of 37 patients with epiretinal membrane peeling surgery for IERM between January 2014 and January 2015. Intraoperative situations during membrane peeling were documented, including complexity of operation, superficial hemorrhage and the state of indocyanine green (ICG) staining...
May 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
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