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https://www.readbyqxmd.com/read/29683803/is-cemented-or-cementless-femoral-stem-fixation-more-durable-in-patients-older-than-75-years-of-age-a-comparison-of-the-best-performing-stems
#1
Michael Tanzer, Stephen E Graves, Andrea Peng, Andrew J Shimmin
BACKGROUND: There is ongoing debate concerning the best method of femoral fixation in older patients receiving primary THA. Clinical studies have shown high survivorship for cemented and cementless femoral stems. Arthroplasty registry studies, however, have universally shown that cementless stems are associated with a higher rate of revision in this patient population. It is unclear if the difference in revision rate is a reflection of the range of implants being used for these procedures rather than the mode of fixation...
April 9, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29681417/fulminant-primary-cardiac-lymphoma-with-sudden-cardiac-death-a-case-report-and-brief-review
#2
Jen-Fang Cheng, Sze-Hwei Lee, Ron-Bin Hsu, Shan-Chi Yu, Chia-Tung Shun, Pang-Shuo Huang, Ying-Hsien Chen, Chii-Ming Lee
Primary cardiac lymphoma (PCL) is very rare, with the variable clinical manifestations potentially leading to a delayed diagnosis. PCL is usually detected incidentally through image studies, whereas the diagnosis can be confirmed via analysis of pericardial effusion, endomyocardial biopsy tissue, or surgical specimens. Although no standard therapy has been established for PCL, without treatment, the prognosis is grave, with the estimated overall survival being approximately 1 year. We report a difficult diagnosis and complicated case of fulminant PCL, which is the first comprehensively reported case of PCL with secondary hemophagocytosis...
April 19, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/29676866/detecci%C3%A3-n-y-expresi%C3%A3-n-de-superant%C3%A3-genos-y-de-resistencia-antimicrobiana-en-aislamientos-obtenidos-de-mujeres-portadoras-de-staphylococcus-aureus-que-cuidan-y-alimentan-ni%C3%A3-os
#3
Yina Marcela Guaca-González, Gladys Fernanda Flórez-Restrepo, José Ignacio Moncayo-Ortíz, Jorge Santacruz-Ibarra, Adalucy Álvarez-Aldana
Introducción. Staphylococcus aureus coloniza mucosas y piel, y causa graves infecciones en el hombre y los animales. Es importante establecer el estatus de portadoras de cepas enterotoxigénicas de este microorganismo en manipuladoras de alimentos, con el fin de prevenir intoxicaciones alimentarias.Objetivo. Establecer las correlaciones entre los genes de enterotoxinas clásicas, el gen tsst-1, la producción de toxinas en cultivo y la resistencia antimicrobiana en aislamientos de S. aureus provenientes de manipuladoras de alimentos que cuidan niños en sus comunidades...
March 15, 2018: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29676865/detecci%C3%A3-n-de-treponema-pallidum-subespecie-pallidum-para-el-diagn%C3%A3-stico-de-s%C3%A3-filis-cong%C3%A3-nita-mediante-reacci%C3%A3-n-en-cadena-de-la-polimerasa-anidada
#4
Gladys Pinilla, Lesly Campos, Andrea Durán, Jeannette Navarrete, Liliana Muñoz
Introducción. La sífilis es una enfermedad producida por Treponema pallidum subespecie pallidum cuya incidencia mundial es de 12 millones de casos por año, aproximadamente; de estos, más de dos millones se presentan en mujeres gestantes, siendo la sífilis congénita la complicación más grave de esta infección en el embarazo.Objetivo. Detectar la presencia de T. pallidum subespecie pallidum en muestras clínicas para el diagnóstico de sífilis congénita mediante reacción en cadena de la polimerasa (PCR) anidada y determinar su concordancia con las pruebas serológicas...
March 15, 2018: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29676344/histopathological-pattern-of-thyroid-diseases-in-zaria-a-10-year-review
#5
Nasiru Raheem, Saad A Ahmed, Modupeola Oa Samaila
Context: Majority of the previous studies on thyroid diseases in Northern Nigeria focussed mainly on neoplastic lesions. The non-neoplastic lesions are more common and constitute more public health burdens. Aim: To determine the histopathological pattern of thyroid diseases in our region and compare our findings with similar studies in Nigeria and elsewhere. Settings and Design: This is a retrospective study carried out at the Department of Pathology, Ahmadu Bello University Teaching Hospital, Zaria, from January 2005 to December 2014 using specified criteria...
January 2018: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29675363/clinical-and-imaging-features-of-pituitary-apoplexy-and-role-of-imaging-in-differentiation-of-clinical-mimics
#6
REVIEW
Pradeep Goyal, Michael Utz, Nishant Gupta, Yogesh Kumar, Manisha Mangla, Sonali Gupta, Rajiv Mangla
To discuss the clinical syndrome, review common imaging findings of pituitary apoplexy (PA) and role of imaging in therapy and follow-up. Also, to review other acute clinical scenarios with similar clinical and/or imaging findings as PA. PA is a severe and potentially life-threatening medical emergency, characterized by constellation of symptoms/signs that occur as a result of acute hemorrhage and/or infarction in pituitary gland. Patients present with acute and sudden onset of symptoms/signs, most commonly with severe headache, vision deficits/ophthalmoplegia, altered mental status, and possible pan hypopituitarism...
March 2018: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29675218/the-self-disproportionation-of-enantiomers-sde-a-menace-or-an-opportunity
#7
REVIEW
Jianlin Han, Osamu Kitagawa, Alicja Wzorek, Karel D Klika, Vadim A Soloshonok
Herein we report on the well-documented, yet not widely known, phenomenon of the self-disproportionation of enantiomers (SDE): the spontaneous fractionation of scalemic material into enantioenriched and -depleted fractions when any physicochemical process is applied. The SDE has implications ranging from the origins of prebiotic homochirality to unconventional enantiopurification methods, though the risks of altering the enantiomeric excess (ee) unintentionally, regrettably, remain greatly unappreciated. While recrystallization is well known as an SDE process, occurrences of the SDE in other processes are much less recognized, e...
February 21, 2018: Chemical Science
https://www.readbyqxmd.com/read/29672561/rich-table-but-short-life-diffuse-idiopathic-skeletal-hyperostosis-in-danish-astronomer-tycho-brahe-1546-1601-and-its-possible-consequences
#8
Sacha Kacki, Petr Velemínský, Niels Lynnerup, Sylva Kaupová, Alizé Lacoste Jeanson, Ctibor Povýšil, Martin Horák, Jan Kučera, Kaare Lund Rasmussen, Jaroslav Podliska, Zdeněk Dragoun, Jiří Smolík, Jens Vellev, Jaroslav Brůžek
The exhumation of Danish astronomer Tycho Brahe (1546-1601) was performed in 2010 to verify speculative views on the cause of his death. Previous analyses of skeletal and hair remains recovered from his grave refuted the presumption that he died from poisoning. These studies also outlined the possibility that he actually died from an acute illness, echoing the rather vague and inaccurate testimony of some historical records. We performed a detailed paleopathological analysis of Tycho Brahe's skeletal remains, along with a reconstruction of his diet based on carbon and nitrogen stable isotopes analysis and an estimate of his physical status (relative body fat) based on medullar and cortical dimensions of the femoral shaft...
2018: PloS One
https://www.readbyqxmd.com/read/29672147/suicide-prevention-training-policies-for-health-care-professionals-across-the-united-states-as-of-october-2017
#9
Janessa M Graves, Jessica L Mackelprang, Sara E Van Natta, Carrie Holliday
OBJECTIVES: To identify and compare state policies for suicide prevention training among health care professionals across the United States and benchmark state plan updates against national recommendations set by the surgeon general and the National Action Alliance for Suicide Prevention in 2012. METHODS: We searched state legislation databases to identify policies, which we described and characterized by date of adoption, target audience, and duration and frequency of the training...
April 19, 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/29671250/measurement-properties-of-thypro-short-form-thypro-39-for-use-in-chinese-patients-with-benign-thyroid-diseases
#10
Carlos K H Wong, Edmond P H Choi, Y C Woo, Brian H H Lang
PURPOSE: To evaluate the validity and reliability of a newly-translated Thyroid-specific Patient-Reported Outcome short-form (ThyPRO-39) instrument for ethnic-Chinese patients suffering from benign thyroid diseases. METHODS: The translation and cross-cultural adaptation of the English ThyPRO-39 were performed using the double forward translation, reconciliation, single backward translation, and cognitive debriefing, followed by a panel review. Cross-sectional data of 308 patients with benign thyroid diseases were utilized for this psychometric evaluation of ThyPRO-39 instrument...
April 18, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29670918/management-of-patients-with-graves-disease-and-orbital-involvement-role-of-spectral-domain-optical-coherence-tomography
#11
Alice Bruscolini, Maurizio La Cava, Magda Gharbiya, Marta Sacchetti, Lucia Restivo, Chiara Nardella, Marco Marenco, Alessandro Lambiase
Purpose: To investigate the role of choroidal thickness evaluation with spectral domain optical coherence tomography (SDOCT) and enhanced depth imaging (EDI) technique in the management of patients with Graves' disease and orbitopathy (GO). Methods: Thirty-six eyes of 18 patients with GO and 36 eyes of 18 age-matched control subjects were included in this retrospective observational study. All the subjects underwent a complete ophthalmological evaluation, including clinical activity score (CAS) and exophthalmometry...
2018: Journal of Immunology Research
https://www.readbyqxmd.com/read/29669235/histological-observations-on-adipocere-in-human-remains-buried-for-21-years-at-the-toma%C3%A5-ica-grave-site-in-bosnia-and-herzegovina
#12
Adis Salihbegović, John Clark, Nermin Sarajlić, Svjetlana Radović, Finlay Finlay, Anes Jogunčić, Emina Spahić, Vedo Tuco
The Tomašica grave-site near Prijedor in the north of Bosnia is reported to be the largest primary mass grave discovered thus far relating to the 1992-95 war. A total of 275 complete bodies and 125 body parts were exhumed from it in 2013. Post mortem examinations of the victims showed that nearly all had died from gunshot injuries but an additional striking feature was the degree of preservation of many of the bodies, even 21 years on, with skin, soft tissues and internal organs still present in abundance and gross structures clearly identifiable...
April 18, 2018: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29669012/characterization-of-the-acute-heat-stress-response-in-gilts-iii-genome-wide-association-studies-of-thermotolerance-traits-in-pigs
#13
K-S Kim, J T Seibert, Z Edea, K L Graves, E-S Kim, A F Keating, L H Baumgard, J W Ross, M F Rothschild
Heat stress (HS) is one of the limiting factors negatively affecting pig production, health, and fertility. Characterizing genomic regions responsible for variation in HS tolerance would be useful in identifying important genetic factor(s) regulating physiological responses to HS. In the present study, we performed genome-wide association analyses for respiration rate (RR), rectal temperature (TR) and skin temperature (TS) during HS in 214 crossbred gilts genotyped for 68,549 single nucleotide polymorphisms (SNP) using the Porcine SNP 70K BeadChip...
April 16, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29668650/impact-of-an-advanced-imaging-utilization-review-program-on-downstream-health-care-utilization-and-costs-for-low-back-pain
#14
Janessa M Graves, Deborah Fulton-Kehoe, Jeffrey G Jarvik, Gary M Franklin
BACKGROUND: Early magnetic resonance imaging (MRI) for acute low back pain (LBP) has been associated with increased costs, greater health care utilization, and longer disability duration in workers' compensation claimants. OBJECTIVES: To assess the impact of a state policy implemented in June 2010 that required prospective utilization review (UR) for early MRI among workers' compensation claimants with LBP. RESEARCH DESIGN: Interrupted time series...
April 17, 2018: Medical Care
https://www.readbyqxmd.com/read/29667215/a-simple-signaling-rule-for-variable-life-adjusted-display-derived-from-an-equivalent-risk-adjusted-cusum-chart
#15
Philipp Wittenberg, Fah Fatt Gan, Sven Knoth
The variable life-adjusted display (VLAD) is the first risk-adjusted graphical procedure proposed in the literature for monitoring the performance of a surgeon. It displays the cumulative sum of expected minus observed deaths. It has since become highly popular because the statistic plotted is easy to understand. But it is also easy to misinterpret a surgeon's performance by utilizing the VLAD, potentially leading to grave consequences. The problem of misinterpretation is essentially caused by the variance of the VLAD's statistic that increases with sample size...
April 17, 2018: Statistics in Medicine
https://www.readbyqxmd.com/read/29666926/segmental-reversal-of-distal-small-intestine-in-short-bowel-syndrome-a-study-on-the-influence-on-postoperative-weight-and-intestinal-topography-in-piglets
#16
Pernille Kock Grave, Sabrina Valentin Thomsen, Pia Susanne Clark, Gunvor Iben Madsen, Niels Qvist, Mark Bremholm Ellebæk
PURPOSE: The objective of the present study was to investigate the effect of segmental reversal of the distal 20 cm of the small intestine in piglets with induced SBS compared to controls with SBS alone. Primary endpoint was postoperative weight change over a period of 1 month. Secondary endpoints were the influence on cell proliferation and mucosal architecture shown by histological analysis. METHODS: Sixteen piglets underwent a 60% resection of the distal small intestine and were randomized into two groups...
April 17, 2018: Pediatric Surgery International
https://www.readbyqxmd.com/read/29666717/aortic-dissection-presenting-as-septic-shock-a-case-report-and-literature-review
#17
Jing Feng, Rui Liu, Sai Ma, Changkui Cao, Wei Zhang, Yang Zhao, Shinan Nie
Acute aortic dissection is a life-threatening clinical emergency, which mostly occurs in aged patients and presents with sharp chest pain. In this paper, we reported a case of acute aortic dissection, which induced septic shock in a young woman, without typical chest pain. The septic shock was possibly due to the bacterial translocation caused by aortic dissection-induced intestinal ischemia and intestinal epithelial barrier dysfunction. Our case appeared as the first case report of aortic dissection presenting as septic shock...
2018: Case Reports in Emergency Medicine
https://www.readbyqxmd.com/read/29665190/comparison-of-emergency-medicine-malpractice-cases-involving-residents-to-non-resident-cases
#18
Kiersten L Gurley, Shamai A Grossman, Margaret Janes, C Winnie Yu-Moe, Ellen Song, Carrie D Tibbles, Nathan I Shapiro, Carlo L Rosen
BACKGROUND: Data are lacking on how emergency medicine (EM) malpractice cases with resident involvement differs from cases that do not name a resident. OBJECTIVES: To compare malpractice case characteristics in cases where a resident is involved (resident case) to cases that do not involve a resident (non-resident case) and to determine factors that contribute to malpractice cases utilizing EM as a model for malpractice claims across other medical specialties. METHODS: We used data from the Controlled Risk Insurance Company (CRICO) Strategies' division Comparative Benchmarking System (CBS) to analyze open and closed EM cases asserted from 2009-2013...
April 17, 2018: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29664539/-atypical-subacute-thyroiditis-in-combination-with-grave-s-disease-diagnostic-difficulties-in-a-case-report
#19
Emmanouela Koutouridou, Tereza Planck, Erik Uddman, Mikael Lantz
Subacute thyroiditis is a common inflammatory disorder of the thyroid gland, possibly of viral etiology, that typically presents with neck pain, fever and tenderness on palpation of the thyroid gland. Graves' disease is an autoimmune thyroid disorder caused by stimulation of the thyroid gland by thyrotropin receptor antibodies (TRAb). The development of Graves´ disease and subacute thyroiditis simultaneously is an uncommon condition and only a few cases have been reported. In this article we present a case of a 46-year old woman diagnosed with Graves´ disease who was started on thiamazole and weeks later developed high fever...
April 13, 2018: Läkartidningen
https://www.readbyqxmd.com/read/29664177/-osler-warned-was-william-osler-a-grave-robber-while-at-mcgill-or-was-he-a-victim-or-perpetrator-of-one-final-practical-joke
#20
James R Wright
Bodysnatching was an illegal way to procure cadavers for anatomical dissection before the existence of effective anatomy legislation. As knowledge of anatomy was fundamental to medical practice, many famous 19th century physicians turned a blind eye to this activity or even participated. Sir William Osler, perhaps the most revered physician of all time, received his medical degree from McGill University in 1872 and then served as pathologist at Montreal General Hospital from 1874 to 1884, where he began a career which culminated in him becoming both the first Professor of Medicine at Johns Hopkins and then Regius Professor at Oxford...
April 17, 2018: Clinical Anatomy
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