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https://www.readbyqxmd.com/read/28944572/sizing-of-patent-ductus-arteriosus-in-adults-for-transcatheter-closure-using-the-balloon-pull-through-technique
#1
Nabil A Shafi, Gagan D Singh, Thomas W Smith, Jason H Rogers
OBJECTIVES: To describe a novel balloon sizing technique used during adult transcatheter patent ductus arteriosus (PDA) closure. In addition, to determine the clinical and procedural outcomes in six patients who underwent PDA balloon sizing with subsequent deployment of a PDA occluder device. BACKGROUND: Transcatheter PDA closure in adults has excellent safety and procedural outcomes. However, PDA sizing in adults can be challenging due to variable defect size, high flow state, or anatomical complexity...
September 25, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28941038/switchable-hydrolase-based-on-reversible-formation-of-supramolecular-catalytic-site-using-a-self-assembling-peptide
#2
Rein V Ulijn, Chunqiu Zhang, Ramim Shafi, Ayala Lampel, Douglas MacPherson, Charalampas Pappas, Vishal Narang, Tong Wang, Charles Madarelli
The reversible regulation of catalytic activity is a feature found in natural enzymes which is not commonly observed in artificial catalytic systems. Here, we fabricate an artificial hydrolase with pH-switchable activity, achieved by introducing a catalytic histidine residue at the terminus of a pH-responsive peptide. The peptide exhibits a conformational transition from random coil to β-sheet by changing the pH from acidic to alkaline. The β-sheet self-assembles to form long fibrils with the hydrophobic edge and histidine residues extending in an ordered array as the catalytic microenvironment, which shows significant esterase activity...
September 22, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28940736/pressure-responsive-nanogel-base-on-alginate-cyclodextrin-with-enhanced-apoptosis-mechanism-for-colon-cancer-delivery
#3
Tolou Hosseinifar, Simin Sheybani, Majid Abdouss, Seyad Alireza Hassani Najafabadi, Mehdi Shafie Ardestani
5-folourouracil (5-Fu) commonly use in the treatment of different kinds of cancer, but limited cellular uptake and death is still a problem. Herein, we report a simple process for the synthesis of pressure-sensitive nanogels that indicate to be appropriate in the delivery of 5-Fu. The hydrogels (Al-CD) prepare by crosslinking of alginate (Al) with modified beta Cyclodextrin (β-CD) as Crosslinker. Next, nanoparticles obtaine by an emulsification method. 5-Fu as model drug loades into the Al-CD nanogels easily by mixing it in aqueous solution with the nanoparticles...
September 22, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28934271/dc-based-smart-pv-powered-home-energy-management-system-based-on-voltage-matching-and-rf-module
#4
Ahmad H Sabry, W Z W Hasan, Mza Ab Kadir, M A M Radzi, S Shafie
The main tool for measuring system efficiency in homes and offices is the energy monitoring of the household appliances' consumption. With the help of GUI through a PC or smart phone, there are various applications that can be developed for energy saving. This work describes the design and prototype implementation of a wireless PV-powered home energy management system under a DC-distribution environment, which allows remote monitoring of appliances' energy consumptions and power rate quality. The system can be managed by a central computer, which obtains the energy data based on XBee RF modules that access the sensor measurements of system components...
2017: PloS One
https://www.readbyqxmd.com/read/28901626/acute-poisonings-during-pregnancy-and-in-other-non-pregnant-women-in-emergency-departments-of-four-government-hospitals-addis-ababa-ethiopia-2010-2015
#5
Mebrahtu Eyasu, Tolesa Dida, Yoseph Worku, Solomon Worku, Mensur Shafie
OBJECTIVE: To characterise acute poisonings in pregnant and non-pregnant women treated at emergency departments of government hospitals in Addis Ababa, Ethiopia, between 2010 and 2015. METHODS: All data for acutely poisoned women were retrospectively collected from patient medical charts at the emergency departments of Saint Paul's Hospital Millennium Medical College, Ras Desta Memorial Hospital, Yekatit 12 Hospital Medical College and Zewditu Memorial Hospital...
September 13, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28893026/superior-vena-cava-as-gateway-to-heart-metastatic-breast-carcinoma-causing-ball-in-a-loop-metastasis-to-right-atrium
#6
Harpreet Singh Sandhu, Sampath Kumar Mahadevappa Mahendrakar, Sulaiman Sadruddin Ladhani, Azizullah Hafizullah Khan, Yunus Shafi Loya
Breast carcinoma is the most common invasive cancer in women worldwide. It metastasizes commonly to bone, lungs, regional lymph nodes and brain. Cardiac metastasis of lung and breast cancers is a known but rare complication of advanced disease with tumour metastasising to pericardium via the locoregional lymphatic system. Here we present a case of 59-year-old female presenting with right upper limb oedema, facial puffiness and features of Superior Vena Cava (SVC) syndrome 15 years after mastectomy and adjuvant chemotherapy, radiotherapy for carcinoma of the right breast...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28890759/general-perceptions-and-awareness-level-among-local-residents-in-penang-island-toward-bats-conservation-efforts
#7
Nur Juliani Shafie, Shahrul Anuar Mohd Sah, Aini Hasanah Abdul Mutalib, Nik Fadzly
The population of bats has declined from year to year caused by human activities such as logging and hunting activities. Since the human factor is linked to the issues of population decline in many animal species, a community-based conservation strategy that involved local communities is needed. We conducted face-to-face surveys among residents in Penang Island to assess knowledge and awareness level toward bats conservation efforts. We collected demographic values such as age, gender, level of education, length of residency as well as their monthly income, since different group in these variable might have different perception...
July 2017: Tropical Life Sciences Research
https://www.readbyqxmd.com/read/28886802/using-reflectance-confocal-microscopy-in-skin-cancer-diagnosis
#8
REVIEW
Attiya Haroon, Shahram Shafi, Babar K Rao
Biopsy and histologic evaluation have been the gold standard to diagnose skin tumors. Reflectance confocal microcopy (RCM) is a noninvasive, innovative diagnostic technique that enables visualization of different skin layers at an almost histologic resolution. RCM has been proven beneficial in management of various cutaneous lesions. This article highlights the clinical significance and future of RCM to diagnose common skin cancers. However, RCM cannot replace currently standard histopathologic diagnosis. More studies are required to better compare the sensitivity and specificity of skin cancer diagnosis using RCM...
October 2017: Dermatologic Clinics
https://www.readbyqxmd.com/read/28878427/mortality-and-disability-adjusted-life-years-dalys-for-common-neglected-tropical-diseases-in-ethiopia-1990-2015-evidence-from-the-global-burden-of-disease-study-2015
#9
A Deribew, B Kebede, G A Tessema, Y A Adama, A Misganaw, T Gebre, A Hailu, S Biadgilign, A Amberbir, B Desalegn, A A Abajobir, O Shafi, S F Abera, N Negussu, B Mengistu, A T Amare, A Mulugeta, Z Kebede, B Mengistu, Z Tadesse, M Sileshi, M Tamiru, E A Chromwel, S D Glenn, J D Stanaway, K Deribe
INTRODUCTION: Neglected tropical diseases (NTDs) are important public health problems in Ethiopia. In 2013, the Federal Ministry of Health (FMOH) has launched a national NTD master plan to eliminate major NTDs of public health importance by 2020. Benchmarking the current status of NTDs in the country is important to monitor and evaluate the progress in the implementation of interventions and their impacts. Therefore, this study aims to assess the trends of mortality and Disability-adjusted Life-Years (DALY) for the priority NTDs over the last 25 years...
2017: Ethiopian Medical Journal
https://www.readbyqxmd.com/read/28877776/maternal-body-weight-trajectories-across-the-life-course-and-risk-of-preterm-delivery
#10
J K Straughen, M Bazydlo, S Havstad, F Shafie-Khorassani, D P Misra
We examined the association between life course body weight percentile trajectories and risk for preterm delivery (PTD). Data about women's weight at birth, age 18, and before pregnancy were obtained by retrospective self-report in a cohort of 1410 black women in metropolitan Detroit. Growth mixture models were used to categorize women with similar weight percentile trajectories across these time points. Log-Poisson models were used to examine the association between the trajectory groups and PTD. Four trajectory groups with different beginning and endpoints of their weight percentiles (high-high, high-low, low-high and low-low) best fit the data...
September 7, 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/28853104/the-association-of-household-food-insecurity-and-the-risk-of-calcium-oxalate-stones
#11
Hamid Shafi, Ahmad-Reza Dorosty Motlagh, Mohammad Bagherniya, Atefeh Daeezadeh, Mohammad Safarian
PURPOSE: Food insecurity has been defined as 'limited or uncertain availability of nutritionally adequate and safe foods', which associated with adverse health consequences in human. Another alarming condition, which is related to several comorbidities is kidney stone. This study aimed to determine the association of household food insecurity and developing kidney stones (calcium oxalate) in adults referred to medical centers of Babol. MATERIALS AND METHODS: This case-control study included 200 participants 18-65 years of ages (100 cases, 100 controls)...
August 29, 2017: Urology Journal
https://www.readbyqxmd.com/read/28839933/assessment-of-medication-adherence-and-the-costs-associated-with-a-calendar-blister-pack-intervention-among-hypertensive-patients-in-malaysia-a-randomized-controlled-trial
#12
Bee Ying Tan, Asrul Akmal Shafie, Mohamed Azmi Ahmad Hassali, Fahad Saleem
OBJECTIVES: To assess the efficacy and costs of a calendar blister packaging intervention used to improve medication adherence. METHOD: A parallel randomized controlled trial was conducted with 73 hypertensive patients (intervention group = 35, control group = 38) at Hospital Kulim, Malaysia, for 7 months. RESULTS: The intervention group demonstrated a significant improvement in medication possession ratio (p < 0.05) and percentage of on-time refills (p < 0...
2017: SAGE Open Medicine
https://www.readbyqxmd.com/read/28811768/clinical-predictors-of-an-abnormal-ultrasound-in-patients-presenting-with-suspected-nephrolithiasis
#13
Salman Tahir Shafi, Roshina Anjum, Tahir Shafi
OBJECTIVE: To determine any clinical features associated with an abnormal ultrasound in patients with suspected nephrolithiasis in an out-patient setting. METHODS: The study design was cross-sectional in nature. The study was conducted at an out-patient nephrology department of a tertiary care facility over a 3 month period. Patients included in the study were 18-80 years old, who presented with unilateral flank or costovertebral angle pain with or without other clinical features suggestive of renal or ureteric calculus based on clinician's judgement...
May 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28805481/a-comparison-of-quality-of-sleep-between-patients-with-chronic-kidney-disease-not-on-hemodialysis-and-end-stage-renal-disease-on-hemodialysis-in-a-developing-country
#14
Salman T Shafi, Tahir Shafi
Few studies have compared quality of sleep between pre-dialysis chronic kidney disease (pre-dialysis CKD) patients and end-stage renal disease patients on dialysis (ESRD) and have found inconsistent results. Objective of this study is to compare quality of sleep between patients with pre-dialysis CKD and ESRD in a developing country. This study was conducted in an out-patient department and hemodialysis unit of a tertiary care facility. Patients included had either pre-dialysis CKD or ESRD. Assessment of quality of sleep was done using Pittsburgh sleep quality index (PSQI)...
November 2017: Renal Failure
https://www.readbyqxmd.com/read/28801442/bangladesh-environmental-enteric-dysfunction-beed-study-protocol-for-a-community-based-intervention-study-to-validate-non-invasive-biomarkers-of-environmental-enteric-dysfunction
#15
Mustafa Mahfuz, Subhasish Das, Ramendra Nath Mazumder, M Masudur Rahman, Rashidul Haque, Md Muzibur Rahman Bhuiyan, Hasina Akhter, Md Shafiqul Alam Sarker, Dinesh Mondal, Syed Shafi Ahmed Muaz, A S M Bazlul Karim, Stephen M Borowitz, Christopher A Moskaluk, Michael J Barratt, William A Petri, Jeffrey I Gordon, Tahmeed Ahmed
INTRODUCTION: Environmental enteric dysfunction (EED) is a subacute inflammatory condition of the small intestinal mucosa with unclear aetiology that may account for more than 40% of all cases of stunting. Currently, there are no universally accepted protocols for the diagnosis, treatment and ultimately prevention of EED. The Bangladesh Environmental Enteric Dysfunction (BEED) study is designed to validate non-invasive biomarkers of EED with small intestinal biopsy, better understand disease pathogenesis and identify potential therapeutic targets for interventions designed to control EED and stunting...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28780315/closed-loop-communication-improves-task-completion-in-pediatric-trauma-resuscitation
#16
Ibrahim Abd El-Shafy, Jennifer Delgado, Meredith Akerman, Francesca Bullaro, Nathan A M Christopherson, Jose M Prince
BACKGROUND: Pediatric trauma care requires effective and clear communication in a time-sensitive manner amongst a variety of disciplines. Programs such as Crew Resource Management in aviation have been developed to systematically prevent errors. Similarly, teamSTEPPS has been promoted in healthcare with a strong focus on communication. We aim to evaluate the ability of closed-loop communication to improve time-to-task completion in pediatric trauma activations. METHODS: All pediatric trauma activations from January to September, 2016 at an American College of Surgeons verified level I pediatric trauma center were video recorded and included in the study...
August 2, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28770894/the-effects-of-gait-training-with-body-weight-support-bws-with-no-body-weight-support-no-bws-in-stroke-patients
#17
Muhammad Asad Ullah, Hina Shafi, Ghazanfar Ali Khan, Arshad Nawaz Malik, Imran Amjad
The purpose of this study was to measure the clinical outcomes for patients with stroke after gait training with body weight support (BWS) and with no body weight support (no-BWS).Experimental group was trained to walk by a BWS system with overhead harness (BWS group), and Control group was trained with full weight bearing walk on their lower extremities. Treatment session comprised of six weeks training. Treatment outcomes were assessed on the basis of Timed 10 Meter Walk Test, Timed Get Up and Go Test and Dynamic Gait Index...
July 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28766581/continuing-medical-education-questions-august-2017
#18
REVIEW
Mehnaz A Shafi
No abstract text is available yet for this article.
August 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28760424/anthocyanins-in-chokeberry-and-purple-maize-attenuate-diet-induced-metabolic-syndrome-in-rats
#19
Maharshi Bhaswant, Siti Raihanah Shafie, Michael L Mathai, Peter Mouatt, Lindsay Brown
OBJECTIVE: Increased consumption of fruits and vegetables as functional foods leads to the reduction of signs of metabolic syndrome. The aim of this study was to measure and compare cardiovascular, liver, and metabolic parameters following chronic administration of the same dose of anthocyanins either from chokeberry (CB) or purple maize (PM) in rats with diet-induced metabolic syndrome. METHODS: Male Wistar rats were fed a maize starch (C) or high-carbohydrate, high-fat diet (H) and divided into six groups for 16 wk...
September 2017: Nutrition
https://www.readbyqxmd.com/read/28755698/non-target-site-resistance-to-als-inhibiting-herbicides-in-a-sagittaria-trifolia-l-population
#20
Bochui Zhao, Danni Fu, Yang Yu, Chengtian Huang, Kecheng Yan, Pingsheng Li, Jamil Shafi, He Zhu, Songhong Wei, Mingshan Ji
Sagittaria trifolia L. is one of the most competitive weeds in rice fields in northeastern China. The continuous use of acetolactate synthase (ALS)-inhibitors has led to the evolution of herbicide resistant S. trifolia. A subpopulation BC1, which was derived from the L1 population, was analyzed using DNA sequencing and ALS enzyme activity assays and levels of resistance to five ALS-inhibiting herbicides was determined. DNA sequencing and ALS enzyme assays revealed no amino acid substitutions and no significant differences in enzyme sensitivity between susceptible and resistant populations...
August 2017: Pesticide Biochemistry and Physiology
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