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https://www.readbyqxmd.com/read/29144299/the-modelling-of-lead-removal-from-water-by-deep-eutectic-solvents-functionalized-cnts-artificial-neural-network-ann-approach
#1
Seef Saadi Fiyadh, Mohammed Abdulhakim AlSaadi, Mohamed Khalid AlOmar, Sabah Saadi Fayaed, Ako R Hama, Sharifah Bee, Ahmed El-Shafie
The main challenge in the lead removal simulation is the behaviour of non-linearity relationships between the process parameters. The conventional modelling technique usually deals with this problem by a linear method. The substitute modelling technique is an artificial neural network (ANN) system, and it is selected to reflect the non-linearity in the interaction among the variables in the function. Herein, synthesized deep eutectic solvents were used as a functionalized agent with carbon nanotubes as adsorbents of Pb(2+)...
November 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29125809/burden-of-hospitalized-childhood-community-acquired-pneumonia-a-retrospective-cross-sectional-study-in-vietnam-malaysia-indonesia-and-the-republic-of-korea
#2
Kah Kee Tan, Duc Anh Dang, Ki Hwan Kim, Cissy Kartasasmita, Hwang Min Kim, Xu-Hao Zhang, Fakrudeen Shafi, Ta-Wen Yu, Emilio Ledesma, Nadia Meyer
BACKGROUND: Few studies describe the community-acquired pneumonia (CAP) burden in children in Asia. We estimated the proportion of all CAP hospitalizations in children from nine hospitals across the Republic of Korea (high-income), Indonesia, Malaysia (middle-income), and Vietnam (low/middle-income). METHODS: Over a one or two-year period, children <5 years hospitalized with CAP were identified using ICD-10 discharge codes. Cases were matched to standardized definitions of suspected (S-CAP), confirmed (C-CAP), or bacterial CAP (B-CAP) used in a pneumococcal conjugate vaccine efficacy study (COMPAS)...
November 10, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29124528/systematic-review-of-economic-burden-of-heart-failure
#3
REVIEW
Asrul Akmal Shafie, Yui Ping Tan, Chin Hui Ng
The aim of this study is to perform a systematic review of the costing methodological approaches adopted by published cost-of-illness (COI) studies. A systematic review was performed to identify cost-of-illness studies of heart failure published between January 2003 and September 2015 via computerized databases such as Pubmed, Wiley Online, Science Direct, Web of Science, and Cumulative Index to Nursing and Allied Health Literature (CINAHL). Costs reported in the original studies were converted to 2014 international dollars (Int$)...
November 10, 2017: Heart Failure Reviews
https://www.readbyqxmd.com/read/29105788/economic-evidence-for-non-pharmacological-asthma-management-interventions-a-systematic-review
#4
REVIEW
Christina-Jane Crossman-Barnes, Adam Peel, Rebekah Fong-Soe-Khioe, Tracey Sach, Andrew Wilson, Garry Barton
Asthma management, education and environmental interventions have been reported as cost effective in a previous review, (Yong and Shafie et al, 2014), but methods used to estimate costs and outcomes were not discussed in detail. This review updates the previous review by providing economic evidence on the cost effectiveness of studies identified after 2012, and a detailed assessment of the methods used in all identified studies. Twelve databases were searched from 1990 to January 2016, and studies included economic evaluations, asthma subjects, and non-pharmacological interventions written in English...
November 6, 2017: Allergy
https://www.readbyqxmd.com/read/29100361/glyoxalase-1-copy-number-variation-in-patients-with-well-differentiated-gastro-entero-pancreatic-neuroendocrine-tumours-gep-net
#5
Mingzhan Xue, Alaa Shafie, Talha Qaiser, Nasir M Rajpoot, Gregory Kaltsas, Sean James, Kishore Gopalakrishnan, Adrian Fisk, Georgios K Dimitriadis, Dimitris K Grammatopoulos, Naila Rabbani, Paul J Thornalley, Martin O Weickert
Background: The glyoxalase-1 gene (GLO1) is a hotspot for copy-number variation (CNV) in human genomes. Increased GLO1 copy-number is associated with multidrug resistance in tumour chemotherapy, but prevalence of GLO1 CNV in gastro-entero-pancreatic neuroendocrine tumours (GEP-NET) is unknown. Methods: GLO1 copy-number variation was measured in 39 patients with GEP-NET (midgut NET, n = 25; pancreatic NET, n = 14) after curative or debulking surgical treatment. Primary tumour tissue, surrounding healthy tissue and, where applicable, additional metastatic tumour tissue were analysed, using real time qPCR...
September 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/29096215/intermittent-theta-burst-stimulation-induces-correlated-changes-in-cortical-and-corticospinal-excitability-in-healthy-older-subjects
#6
Tamara Gedankien, Peter J Fried, Alvaro Pascual-Leone, Mouhsin M Shafi
OBJECTIVE: We studied the correlation between motor evoked potentials (MEPs) and early TMS-evoked EEG potentials (TEPs) from single-pulse TMS before and after intermittent Theta Burst Stimulation (iTBS) to the left primary motor cortex (M1) in 17 healthy older participants. METHODS: TMS was targeted to the hand region of M1 using a MRI-guided navigated brain stimulation system and a figure-of-eight biphasic coil. MEPs were recorded from the right first dorsal interosseous muscle using surface EMG...
September 28, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29068720/detection-and-molecular-characterization-of-methicillin-resistant-staphylococcus-aureus-from-table-eggs-in-haripur-pakistan
#7
Muhammad Ali Syed, Syeda Hala Hussain Shah, Yasmin Sherafzal, Syed Shafi-Ur-Rehman, Mushtaq Ahmed Khan, John B Barrett, Tiffanie A Woodley, Bushra Jamil, Shahid Ahmad Abbasi, Charlene R Jackson
Table eggs are nutritionally important food consumed globally. Despite being protected inside the hard shell and a semipermeable membrane, the egg contents may be contaminated with microbes and thus become a possible carrier of infectious agents to humans. A number of medically significant bacterial species such as Salmonella enterica, Listeria monocytogenes, and Yersinia enterocolitica have already been reported from table eggs. More important is the presence of antimicrobial-resistant bacterial strains in this food source...
October 25, 2017: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/29067057/a-comparison-of-anxiety-and-depression-between-pre-dialysis-chronic-kidney-disease-patients-and-hemodialysis-patients-using-hospital-anxiety-and-depression-scale
#8
Salman T Shafi, Tahir Shafi
OBJECTIVE: Tocompare frequency of anxiety and depression between pre-dialysis chronic kidney disease (CKD) and hemodialysis patients (ESRD) in Pakistan. METHODS: This study was conducted in an out-patient department and hemodialysis unit of Sharif Medical City Hospital. Inclusion criteria included age above 18 years and a diagnosis of CKD including both pre-dialysis CKD and ESRD patients. Patients were screened for anxiety and depression using hospital anxiety and depression scale (HADS)...
July 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29064582/establishment-of-a-platform-for-molecular-and-immunological-characterization-of-the-rna-dependent-rna-polymerase-ns5b-of-an-egyptian-hcv-isolate
#9
Hossam Gewaid, Ahmed A Mesalam, Ahmed A Ibrahim, Dina N Abdel Shafy, Rola N Abdel Shafy, Nahed Emara, Soha M Hamdy, Mohy Gewaid, Mahmoud M Bahgat
The present work aimed at establishing a platform to enable frequent characterization of the HCV RNA-dependent-RNA-polymerase from Egyptian clinical isolates. Subjecting amplified HCV-NS5B coding gene from Egyptian patient's serum to sequencing, multiple alignment, and phylogenetic analysis confirmed its subtype 4a origin. Nucleotide sequence analysis revealed presence of an additional start codon at the beginning of the NS5B gene. Peptide sequence alignment demonstrated presence of unique amino acid residues in our 4a-NS5B sequence distinct from the JFH-1-NS5B sequence as well as unique amino acids compared to other genotypes...
October 24, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/29061098/the-cognitive-reserve-model-in-the-development-of-delirium-the-successful-aging-after-elective-surgery-study
#10
Sevdenur Cizginer, Edward Marcantonio, Sarinnapha Vasunilashorn, Alvaro Pascual-Leone, Mouhsin Shafi, Eva M Schmitt, Sharon K Inouye, Richard N Jones
We evaluated the role of cognitive and brain reserve markers in modifying the risk of postoperative delirium associated with a pathophysiologic marker. The Successful Aging after Elective Surgery study (SAGES) enrolled 556 adults age ≥70 years without dementia scheduled for major surgery. Patients were assessed preoperatively and daily during hospitalization for delirium. We used C-reactive protein (CRP) as a pathophysiologic marker of inflammation, previously associated with delirium. Markers of reserve included vocabulary knowledge, education, cognitive activities, occupation type and complexity, head circumference, intracranial volume, and leisure activities...
November 2017: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/29055090/performance-of-nontraditional-hyperglycemia-biomarkers-by-chronic-kidney-disease-status-in-older-adults-with-diabetes-results-from-the-atherosclerosis-risk-in-communities-study
#11
Molly Jung, Bethany Warren, Morgan Grams, Yuenting Diana Kwong, Tariq Shafi, Josef Coresh, Casey M Rebholz, Elizabeth Selvin
BACKGROUND: In persons with chronic kidney disease (CKD), hemoglobin A1c (HbA1c) may be a problematic measure of glycemic control. Glycated albumin and fructosamine have been proposed as better markers of hyperglycemia in CKD. We investigated associations of HbA1c, glycated albumin, and fructosamine with fasting glucose by CKD categories. METHODS: Cross-sectional analysis of 1,665 Atherosclerosis Risk in Communities Study participants with diagnosed diabetes aged 65 years or older...
October 20, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/29039340/in-vitro-antibacterial-and-antifungal-activities-of-different-solvent-extracted-samples-from-the-stem-of-euphorbia-heliscopia
#12
Jehan Bakht, - Faiza, Mohammad Shafi, Arshad Iqbal
This paper presents the anti-microbial potentials of methanol, ethyl acetate, n-hexane, butanol and water extracted samples from the stem of Euphorbia heliscopia against S. aureus (Gram positive), B. subtilis (Gram positive), P. aeruginosa (Gram negative), K. pneumonia (Gram negative), E. coli (Gram negative), C. albicans (fungal specie) by discs diffusion susceptibility assay using 0.5 and 1mg disc(-1) concentrations. Our results showed that all the extracted samples from the stem of E. heliscopia exhibited varying degree of antimicrobial activity...
July 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29031233/forensic-and-clinical-significance-of-serum-amylase-lipase-and-gamma-glutamyl-transferase-as-predictors-of-outcome-in-head-injured-patients
#13
Mona Mohamed Abo El-Noor, Naema Mahmoud ElHosary, Hytham Ibrahim Elatrozy, Hussein Mohamed Abou Elgheit, Ahmed Mohamed Elbelkasy, Ahmed Gamal Fath, Ghada Hamed El-Shafy
Head trauma is one of the leading causes of death and disability worldwide. Combined head lesions consist of more than one form of lesions. Biochemical markers of brain injury are used in determining the extent of brain injury and predicting its outcomes. The aim of this study was to investigate the forensic and clinical significance of serum amylase, lipase and gamma glutamyl transferase (GGT) as predictors of the outcome in head injured patients. PATIENTS AND METHODS: Sixty head injured patients were enrolled and subjected to personal history taking, general and local physical examination...
October 4, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29027315/cost-effectiveness-analysis-of-carbetocin-during-cesarean-section-in-a-high-volume-maternity-unit
#14
Hian Yan Voon, Asrul A Shafie, Mohamad A Bujang, Haris N Suharjono
AIM: To evaluate the cost effectiveness of carbetocin compared to oxytocin when used as prophylaxis against post-partum hemorrhage (PPH) during cesarean deliveries. METHODS: A systematic review of the literature was performed to identify randomized controlled trials that compared the use of carbetocin to oxytocin in the context of cesarean deliveries. Cost effectiveness analysis was then performed using secondary data from the perspective of a maternity unit within the Malaysian Ministry of Health, over a 24 h time period...
October 13, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29022146/cupriavidus-malaysiensis-sp-nov-a-novel-poly-3-hydroxybutyrate-co-4-hydroxybutyrate-accumulating-bacterium-isolated-from-the-malaysian-environment
#15
Hema Ramachandran, Nur Asilla Hani Shafie, Kumar Sudesh, Mohamad Noor Azizan, Mohamad Isa Abdul Majid, Al-Ashraf Abdullah Amirul
Bacterial classification on the basis of a polyphasic approach was conducted on three poly(3 hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] accumulating bacterial strains that were isolated from samples collected from Malaysian environments; Kulim Lake, Sg. Pinang river and Sg. Manik paddy field. The Gram-negative, rod-shaped, motile, non-sporulating and non-fermenting bacteria were shown to belong to the genus Cupriavidus of the Betaproteobacteria on the basis of their 16S rRNA gene sequence analyses...
October 11, 2017: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/29017465/frequency-of-arrhythmia-symptoms-and-acceptability-of-implantable-cardiac-monitors-in-hemodialysis-patients
#16
Naya El Hage, Bernard G Jaar, Alan Cheng, Chloe Knight, Elena Blasco-Colmenares, Luis Gimenez, Eliseo Guallar, Tariq Shafi
BACKGROUND: Arrhythmia-related complications and sudden death are common in dialysis patients. However, routine cardiac monitoring has so far not been feasible. Miniaturization of implantable cardiac monitors offers a new paradigm for detection and management of arrhythmias in dialysis patients. The goal of our study was to determine the frequency of arrhythmia-related symptoms in hemodialysis patients and to assess their willingness to undergo implantation of a cardiac monitor. METHODS: We conducted a survey of in-center hemodialysis patients at a hemodialysis clinic in Baltimore, Maryland...
October 10, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28983801/electronic-health-data-predict-outcomes-after-aneurysmal-subarachnoid-hemorrhage
#17
Sahar F Zafar, Eva N Postma, Siddharth Biswal, Lucas Fleuren, Emily J Boyle, Sophia Bechek, Kathryn O'Connor, Apeksha Shenoy, Durga Jonnalagadda, Jennifer Kim, Mouhsin S Shafi, Aman B Patel, Eric S Rosenthal, M Brandon Westover
BACKGROUD: Using electronic health data, we sought to identify clinical and physiological parameters that in combination predict neurologic outcomes after aneurysmal subarachnoid hemorrhage (aSAH). METHODS: We conducted a single-center retrospective cohort study of patients admitted with aSAH between 2011 and 2016. A set of 473 predictor variables was evaluated. Our outcome measure was discharge Glasgow Outcome Scale (GOS). For laboratory and physiological data, we computed the minimum, maximum, median, and variance for the first three admission days...
October 5, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28971980/metabolomic-alterations-associated-with-cause-of-ckd
#18
Morgan E Grams, Adrienne Tin, Casey M Rebholz, Tariq Shafi, Anna Köttgen, Ronald D Perrone, Mark J Sarnak, Lesley A Inker, Andrew S Levey, Josef Coresh
BACKGROUND AND OBJECTIVES: Causes of CKD differ in prognosis and treatment. Metabolomic indicators of CKD cause may provide clues regarding the different physiologic processes underlying CKD development and progression. DESIGN, SETTING, PARTICIPANTS & MEASUREMENTS: Metabolites were quantified from serum samples of participants in the Modification of Diet in Renal Disease (MDRD) Study, a randomized controlled trial of dietary protein restriction and BP control, using untargeted reverse phase ultraperformance liquid chromatography tandem mass spectrometry quantification...
November 7, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28965628/cyclin-d1-is-significantly-associated-with-stage-of-tumor-and-predicts-poor-survival-in-endometrial-carcinoma-patients
#19
Mohamad Nidal Khabaz, Amer Shafie Abdelrahman, Nadeem Shafique Butt, Basim Al-Maghrabi, Jaudah Al-Maghrabi
Cyclin D1 overexpression has been described to have oncogenic role and association with diagnosis, prognosis and survival in various tumors. This study will describe the immunohistochemical phenotype of cyclin D1, and investigate the correlation between these patterns of expression and clinicopathological parameters of endometrial carcinomas, to conclude the clinical relevance of cyclin D1 expression in the evolution of endometrial neoplasms. This study employed 101 endometrial tissue samples which include 71 endometrial carcinomas and thirty normal and benign endometrium cases...
October 2017: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/28964445/determination-of-cost-effectiveness-threshold-for-health-care-interventions-in-malaysia
#20
RANDOMIZED CONTROLLED TRIAL
Yen Wei Lim, Asrul Akmal Shafie, Gin Nie Chua, Mohammed Azmi Ahmad Hassali
BACKGROUND: One major challenge in prioritizing health care using cost-effectiveness (CE) information is when alternatives are more expensive but more effective than existing technology. In such a situation, an external criterion in the form of a CE threshold that reflects the willingness to pay (WTP) per quality-adjusted life-year is necessary. OBJECTIVES: To determine a CE threshold for health care interventions in Malaysia. METHODS: A cross-sectional, contingent valuation study was conducted using a stratified multistage cluster random sampling technique in four states in Malaysia...
September 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
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