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https://www.readbyqxmd.com/read/28723470/sexually-transmitted-disease-and-male-infertility-a-systematic-review
#1
REVIEW
Mikkel Fode, Ferdinando Fusco, Larry Lipshultz, Wolfgang Weidner
CONTEXT: Theoretically, sexually transmitted diseases (STDs) have the potential to disrupt male fertility; however, the topic remains controversial. OBJECTIVE: To describe the possible association between STDs and male infertility and to explore possible pathophysiologic mechanisms. EVIDENCE ACQUISITION: We performed a systematic literature review in accordance with the PRISMA guidelines. PubMed, Embase, and the Cochrane Library were searched for articles published before January 1, 2016, using the MeSH terms for a variety of STDs and infertility...
October 2016: European Urology Focus
https://www.readbyqxmd.com/read/28722366/-large-vessel-vasculitis-pathogenesis-diagnostic-and-medical-management
#2
Alireza Sadrkhah, Jörg D Seebach, Yannick Muller
Large vessels vasculitis includes two diseases : 1) giant cell arteritis, formerly known as Horton's arteritis and 2) Takayasu arteritis. In this article, we will describe and compare the epidemiology, pathogenesis, diagnostic criteria and medical management of both vasculitis. T helper (Th) 1 and Th17 responses, genetic links and the role of viral (varicella zoster) and bacterial infection (Mycoplasma pneumoniae or Chlamydia pneumoniae) will be discussed. Classification criteria, inflammation biomarkers and progress in imaging tools will also be described...
April 5, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28717267/semen-culture-and-the-assessment-of-genitourinary-tract-infections
#3
REVIEW
Michael Solomon, Ralf Henkel
The male factor contributes approximately 50% to infertility-related cases in couples with an estimated 12%-35% of these cases attributable to male genital tract infections. Depending on the nature of the infection, testicular sperm production, sperm transport, and sperm function can be compromised. Yet, infections are potentially treatable causes of infertility. Male genital tract infections are increasingly difficult to detect. Moreover, they often remain asymptomatic ("silent") with the result that they are then passed on to the relevant sexual partner leading to fertilization and pregnancy failure as well as illness of the offspring...
July 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28698342/prevalence-and-antibiotic-resistance-of-mycoplasma-genitalium-among-sti-clinic-attendees-in-western-canada-a-cross-sectional-analysis
#4
Jennifer Gratrix, Sabrina Plitt, LeeAnn Turnbull, Petra Smyczek, Judith Brandley, Ron Scarrott, Prenilla Naidu, Penny Parker, Brenda Blore, Amy Bull, Sandy Shokoples, Lindsay Bertholet, Irene Martin, Max Chernesky, Ron Read, Ameeta Singh
OBJECTIVES: To determine the prevalence and correlates of Mycoplasma genitalium (MG) infection among men and women, determine the prevalence of gene mutations conferring resistance and compare test performance of female specimen types. METHODS: A cross-sectional study was conducted on specimens collected for gonorrhoea (NG, Neisseria gonorrhoeae) and chlamydia (CT, Chlamydia trachomatis) among male and female Alberta STI clinic attendees using the M. genitalium transcription-mediated amplification-research use only test...
July 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28697843/uriswab-an-effective-transport-medium-for-nucleic-acid-detection-of-chlamydia-trachomatis-mycoplasma-genitalium-and-neisseria-gonorrhoeae
#5
Anna-Maria G Costa, Suzanne M Garland, Rebecca Guy, Handan Wand, Sepehr N Tabrizi
Background: Patient self-sampling allows for remote collection and return to clinic or laboratory by post. Urine samples, although convenient, are challenging to post. This study evaluated UriSwab (Copan, Brescia, Italy) as a collection and transport vessel for Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and Mycoplasma genitalium (MG) detection by polymerase chain reaction, compared with flocked swab and neat urine. Methods: Five replicates of each specimen type were prepared from previously characterised urine samples (n=330), stored at room temperature (RT) or 37°C, then extracted on day 1, 3, 7, 10 and 16 (VERSANT kPCR Sample Prep System, Siemens, Munich, Germany)...
July 12, 2017: Sexual Health
https://www.readbyqxmd.com/read/28681823/comparative-analysis-of-syndromic-case-management-and-polymerase-chain-reaction-based-diagnostic-assays-for-treatment-of-neisseria-gonorrhoeae-chlamydia-trachomatis-and-genital-mycoplasmas-in-patients-of-genitourinary-discharge
#6
Nazneen Arif, Sujeesh Sebastian, Neena Khanna, Seema Sood, Benu Dhawan
To respond to the situation of high prevalence and need for effective treatment for sexually transmitted infections (STIs) in low-resource settings, syndromic diagnostic approach was recommended by the World Health Organization and was adopted by National AIDS Control Organization at the primary health centre level. A retrospective study was undertaken in symptomatic patients attending an STI clinic to validate the syndromic approach for genitourinary discharge syndrome. For aetiological diagnosis, culture and/or polymerase chain reaction was used...
April 2017: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28670432/relationship-between-chlamydia-ureaplasma-mycoplasma-genital-detection-with-semen-concentration-and-motility-among-greek-men
#7
Ageliki Gerovassili, Ourania Marcandona, Byron Asimakopoulos, Vasilis Karavasilis, Maria Panopoulou, Alexandros Ikonomidis
One hundred and seventy two men at the State of Thessaly, Greece, inquiring semen analysis were enrolled in the study in order to investigate the incidence of Chlamydia, Ureaplasma and Mycoplasma (C-U-M) genera in respect to total sperm number (TSN), progressive motility (grades a and b) and total motility (grades a, b and c). Putative relation of C-U-M acquirement with sexual behavior was also investigated. Incidence of C-U-M among non-oligozoospermic and oligozoospermic men was similar. Νο correlation of C-U-M carriage to either oligozoospermia or asthenozoospermia was found...
July 2017: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/28646898/prevalence-of-chlamydia-trachomatis-neisseria-gonorrhoeae-mycoplasma-genitalium-and-ureaplasma-urealyticum-infections-using-a-novel-isothermal-simultaneous-rna-amplification-testing-method-in-infertile-males
#8
Ling Qing, Qi-Xiang Song, Jian-Li Feng, Hai-Yan Li, Guiming Liu, Hai-Hong Jiang
BACKGROUND: The purpose of this study was to evaluate the prevalence of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium and Ureaplasma urealyticum infections in infertile men that consulted our outpatient departments using a novel simultaneous amplification testing (SAT) that is RNA-detection based. The possible impact of C. trachomatis, N. gonorrhoeae, M. genitalium and U. urealyticum infections on semen parameters was also noted in the present study. METHODS: A total of 2607 males that were diagnosed with infertility were included in this study...
June 24, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/28628024/-evaluation-of-dynamic-telomere-length-shortening-of-lymphocytes-in-immunocompromised-children-with-chronic-diseases-of-the-respiratory
#9
E Khalturina, I Nesterova
Nowadays it is common to observe the growth of viral-viral and viral-bacterial co-infections in children of different ages, due to dysfunction of lymphocytes (DL), which can be connected with the process of the accelerated shortening of the end structures of chromosomal telomeres, telomere length changes are described in lymphocytes of children with chronic mono-infections. The conducted study has shown the shortening of telomere lymphocytes in children with CDRT seropositive for mixed-herpes viral infections (herpes simplex virus, virus, Epstein-Barr virus and cytomegalovirus in various combinations) and for bacterial co-infections - Chlamydia trachomatis and (or) Mycoplasma pneumoniae...
May 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28617561/cervicovaginal-bacteria-and-fungi-in-pregnant-diabetic-and-non-diabetic-women-a-multicenter-observational-cohort-study
#10
A Lukic, A Napoli, I Santino, P Bianchi, F Nobili, G Ciampittiello, M R Nardone, M Santomauro, M Di Properzio, D Caserta
OBJECTIVE: We evaluated the prevalence of cervicovaginal Bacteria, group B Streptococcus (GBS), Gardnerella vaginalis (GV), Candida spp., Chlamydia trachomatis (CT), Mycoplasma hominis (MH) and Ureaplasma urealyticum (UU) in pregnant women with and without diabetes mellitus (DM). PATIENTS AND METHODS: Cervicovaginal swabs were gathered from 473 pregnant patients divided into 127 diabetic and 346 non-diabetic. The results were correlated to gestational age, parity and glycemic control...
May 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28608794/mycoplasma-genitalium-antibiotic-resistance-mediating-mutations-in-canadian-women-with-or-without-chlamydia-trachomatis-infection
#11
Max A Chernesky, Dan Jang, Irene Martin, Linda M N Hoang, Prenilla Naidu, Paul N Levett, John Wylie, Anu Rebbapragada, Sam Ratnam, Marek Smieja, Barbara Weinbaum, Damon Getman
Testing remnant Aptima specimens from women infected with Chlamydia trachomatis detected 13.4% (53/396) with Mycoplasma genitalium compared with 5.4% (22/406) in matched C. trachomatis-negative women. Overall, 9.4% (provincial ranges of 3-20%) were infected with M. genitalium and resistance mediating mutations were found in 47.3% (26/55) to macrolides and 1.9% (1/53) to fluoroquinolones by sequencing.
July 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28590237/evaluation-of-self-collected-rectal-swabs-for-the-detection-of-bacteria-responsible-for-sexually-transmitted-infections-in-a-cohort-of-hiv-1-infected-patients
#12
Sophie Edouard, Catherine Tamalet, Hervé Tissot-Dupont, Philippe Colson, Amélie Ménard, Isabelle Ravaux, Catherine Dhiver, Christelle Tomei, Andreas Stein, Didier Raoult
PURPOSE: The standard approach to screening sexually transmitted infections (STIs) has often been restricted to urogenital specimens. Most current guidelines, however, also recommend testing extra-genital sites, including rectal locations, because asymptomatic rectal carriage of pathogens has often been reported. The aim of our study was to evaluate self-collected rectal swabs to screen bacterial STIs in HIV-infected patients in Marseille, France. METHODOLOGY: Between January 2014 and December 2015, 118 HIV-infected patients (93 males and 25 females) agreed to self-sample anal swabs for detection of bacterial STI...
June 8, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28568680/mucositis-secondary-to-chlamydia-pneumoniae-infection-expanding-the-mycoplasma-pneumoniae-induced-rash-and-mucositis-concept
#13
Ander Mayor-Ibarguren, Marta Feito-Rodriguez, Jéssica González-Ramos, Teresa Del Rosal-Rabes, Francisco Javier González-Sainz, Alba Sánchez-Orta, Raul de Lucas-Laguna
The term Mycoplasma pneumoniae-induced rash and mucositis (MIRM) was recently proposed to identify the mucocutaneous condition secondary to M. pneumoniae infection that had historically been regarded among the more confusing pathologies of erythema multiforme and Stevens-Johnson syndrome. Based on a number of previous reports, these syndromes require differentiation since they have different prognoses and specific treatment requirements. We report a case of oral and genital erosions that strongly resembled MIRM without rash but were found to be secondary to a Chlamydia pneumoniae infection...
June 1, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28559729/biosynthesis-of-oxytetracycline-by-streptomyces-rimosus-%C3%A2-past-present-and-future-directions-in-the-development%C3%A2-of-tetracycline-antibiotics
#14
REVIEW
Hrvoje Petković, Tadeja Lukežič, Jagoda Šušković
Natural tetracycline (TC) antibiotics were the first major class of therapeutics to earn the distinction of 'broad-spectrum antibiotics' and they have been used since the 1940s against a wide range of both Gram-positive and Gram-negative pathogens, mycoplasmas, intracellular chlamydiae, rickettsiae and protozoan parasites. The second generation of semisynthetic tetracyclines, such as minocycline and doxycycline, with improved antimicrobial potency, were introduced during the 1960s. Despite emerging resistance to TCs erupting during the 1980s, it was not until 2006, more than four decades later, that a third--generation TC, named tigecycline, was launched...
March 2017: Food Technology and Biotechnology
https://www.readbyqxmd.com/read/28529540/the-potential-role-of-infectious-agents-and-pelvic-inflammatory-disease-in-ovarian-carcinogenesis
#15
REVIEW
Kasper Ingerslev, Estrid Hogdall, Tine Henrichsen Schnack, Wojciech Skovrider-Ruminski, Claus Hogdall, Jan Blaakaer
BACKGROUND: The etiological cause of ovarian cancer is poorly understood. It has been theorized that bacterial or viral infection as well as pelvic inflammatory disease could play a role in ovarian carcinogenesis. AIM: To review the literature on studies examining the association between ovarian cancer and bacterial or viral infection or pelvic inflammatory disease. METHODS: Database search through MEDLINE, applying the medical subject headings: "Ovarian neoplasms", AND "Chlamydia infections", "Neisseria gonorrhoeae", "Mycoplasma genitalium", "Papillomaviridae", or "pelvic inflammatory disease"...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/28508147/identification-of-beta-lactamases-and-beta-lactam-related-proteins-in-human-pathogenic-bacteria-using-a-computational-search-approach
#16
Aniel Jessica Leticia Brambila-Tapia, Ernesto Perez-Rueda, Humberto Barrios, Nory Omayra Dávalos-Rodríguez, Ingrid Patricia Dávalos-Rodríguez, Ernesto Germán Cardona-Muñoz, Mario Salazar-Páramo
A systematic analysis of beta-lactamases based on comparative proteomics has not been performed thus far. In this report, we searched for the presence of beta-lactam-related proteins in 591 bacterial proteomes belonging to 52 species that are pathogenic to humans. The amino acid sequences for 19 different types of beta-lactamases (ACT, CARB, CifA, CMY, CTX, FOX, GES, GOB, IMP, IND, KPC, LEN, OKP, OXA, OXY, SHV, TEM, NDM, and VIM) were obtained from the ARG-ANNOT database and were used to construct 19 HMM profiles, which were used to identify potential beta-lactamases in the completely sequenced bacterial proteomes...
May 16, 2017: Current Microbiology
https://www.readbyqxmd.com/read/28493440/tear-production-intraocular-pressure-and-conjunctival-bacterial-flora-in-selected-captive-wild-ruminants
#17
Pavel Kvapil, Tina Pirš, Brigita Slavec, Roman Luštrik, Tadej Zemljič, Eva Bártová, Bojana Stranjac, Marjan Kastelic
OBJECTIVE: Evaluation of tear production (Schirmer's tear test, STT) and measurement of intraocular pressure (IOP) were performed in a population of captive wild ungulates in a Slovenian ZOO during routine annual health check. ANIMALS STUDIED: In total, 10 fallow deer (Dama dama), 25 mouflons (Ovis aries musimon), 20 alpine ibexes (Capra ibex), and three alpine chamois (Rupicapra rupicapra) were included in the study. METHODS: Tear production was performed by Schirmer's tear test, IOP was measured with an applanation tonometer, and ophthalmological examination was conducted with slit-lamp biomicroscopy and indirect ophthalmoscopy...
May 11, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/28480285/influence-of-antibiotics-on-the-detection-of-bacteria-by-culture-based-and-culture-independent-diagnostic-tests-in-patients-hospitalized-with-community-acquired-pneumonia
#18
Aaron M Harris, Anna M Bramley, Seema Jain, Sandra R Arnold, Krow Ampofo, Wesley H Self, Derek J Williams, Evan J Anderson, Carlos G Grijalva, Jonathan A McCullers, Andrew T Pavia, Richard G Wunderink, Kathryn M Edwards, Jonas M Winchell, Lauri A Hicks
BACKGROUND: Specimens collected after antibiotic exposure may reduce culture-based bacterial detections. The impact on culture-independent diagnostic tests is unclear. We assessed the effect of antibiotic exposure on both of these test results among patients hospitalized with community-acquired pneumonia (CAP). METHODS: Culture-based bacterial testing included blood cultures and high-quality sputum or endotracheal tube (ET) aspirates; culture-independent testing included urinary antigen testing (adults) for Streptococcus pneumoniae and Legionella pneumophila and polymerase chain reaction (PCR) on nasopharyngeal and oropharyngeal (NP/OP) swabs for Mycoplasma pneumoniae and Chlamydia pneumoniae...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28475737/evolution-of-acute-infection-with-atypical-bacteria-in-a-prospective-cohort-of-children-with-community-acquired-pneumonia-receiving-amoxicillin
#19
Cristiana M Nascimento-Carvalho, Gabriel Xavier-Souza, Ana-Luisa Vilas-Boas, Maria-Socorro H Fontoura, Aldina Barral, Mirja Puolakkainen, Olli Ruuskanen
Background: Atypical bacteria are treatable causative agents of community-acquired pneumonia (CAP). However, there is no conclusive evidence that a child with CAP should receive empirical treatment against such agents. Objectives: We assessed the possibility of association between clinical failure and acute infection by these bacteria among children with CAP treated with amoxicillin. Patients and methods: Patients aged 2-59 months with non-severe CAP received amoxicillin during prospective follow-up...
May 5, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28419691/the-low-diverse-gastric-microbiome-of-the-jellyfish-cotylorhiza-tuberculata-is-dominated-by-four-novel-taxa
#20
Tomeu Viver, Luis H Orellana, Janet K Hatt, Mercedes Urdiain, Sara Díaz, Michael Richter, Josefa Antón, Massimo Avian, Rudolf Amann, Konstantinos T Konstantinidis, Ramon Rosselló-Móra
Cotylorhiza tuberculata is an important scyphozoan jellyfish producing population blooms in the Mediterranean probably due to pelagic ecosystem's decay. Its gastric cavity can serve as a simple model of microbial-animal digestive associations, yet poorly characterized. Using state-of-the-art metagenomic population binning and catalyzed reporter deposition fluorescence in situ hybridization (CARD-FISH), we show that only four novel clonal phylotypes were consistently associated with multiple jellyfish adults...
April 17, 2017: Environmental Microbiology
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