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Cryoablation

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https://www.readbyqxmd.com/read/29774073/polypyrrole-chitosan-conductive-biomaterial-synchronizes-cardiomyocyte-contraction-and-improves-myocardial-electrical-impulse-propagation
#1
Zhi Cui, Nathan C Ni, Jun Wu, Guo-Qing Du, Sheng He, Terrence M Yau, Richard D Weisel, Hsing-Wen Sung, Ren-Ke Li
Background: The post-myocardial infarction (MI) scar interrupts electrical impulse propagation and delays regional contraction, which contributes to ventricular dysfunction. We investigated the potential of an injectable conductive biomaterial to restore scar tissue conductivity and re-establish synchronous ventricular contraction. Methods: A conductive biomaterial was generated by conjugating conductive polypyrrole (PPY) onto chitosan (CHI) backbones. Trypan blue staining of neonatal rat cardiomyocytes (CMs) cultured on biomaterials was used to evaluate the biocompatibility of the conductive biomaterials...
2018: Theranostics
https://www.readbyqxmd.com/read/29770311/-super-active-surveillance-mri-ultrasound-fusion-biopsy-and-ablation-for-less-invasive-management-of-prostate-cancer
#2
REVIEW
Jonathan B Bloom, Samuel A Gold, Graham R Hale, Kareem N Rayn, Vikram K Sabarwal, Ivane Bakhutashvili, Vladimir Valera, Baris Turkbey, Peter A Pinto, Bradford J Wood
Multiparametric magnetic resonance imaging (mpMRI) of the prostate has allowed clinicians to better visualize and target suspicious lesions during biopsy. Targeted prostate biopsies give a more accurate representation of the true cancer volume and stage so that appropriate treatment or active surveillance can be selected. Advances in technology have led to the development of MRI and ultrasound fusion platforms used for targeted biopsies, monitoring cancer progression, and more recently for the application of focal therapy...
April 2018: Gland Surgery
https://www.readbyqxmd.com/read/29770216/assessment-of-a-novel-cryoablation-device-for-the-endovascular-treatment-of-cardiac-tachyarrhythmias
#3
John M Baust, Anthony Robilotto, Peter Guerra, Kristi K Snyder, Robert G Van Buskirk, Marc Dubuc, John G Baust
Objectives: Cryoablation is an effective alternative treatment for cardiac arrhythmias offering shortened recovery and reduced side effects. As the use of cryoablation increases, the need for new devices and procedures has emerged. This has been driven by technological limitations including lengthy periods to generate a single lesion (3-5 min), uncertain transmurality, and differential efficacy. Furthermore, due to limited ablation capacity under high heat loads, cryo has had limited success in the treatment of ventricular arrhythmias...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/29741689/cryoballoon-ablation-in-the-elderly-one-year-outcome-and-safety-of-the-second-generation-28mm-cryoballoon-in-patients-over-75-years-old
#4
Verena Tscholl, Tina Lin, Abdullah Khaled-A Lsharaf, Barbara Bellmann, Patrick Nagel, Klaus Lenz, Ulf Landmesser, Mattias Roser, Andreas Rillig
Aims: The efficacy of the second-generation cryoballoon (CB) ablation in patients with atrial fibrillation (AF) has been demonstrated previously. Data on the efficacy of CB ablation in elderly patients is missing. The aim of this study was to evaluate the long-term success rate of pulmonary vein isolation (PVI) in patients ≥75 years vs. <75 years using the second-generation 28mm CB. Methods and results: Eighty patients [n = 40 ≥75 years (Group 1); n = 40 <75 years (Group 2)] with paroxysmal [n = 37 (46%) or persistent (n = 43 (54%)] AF were included...
May 1, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29735858/comparison-of-the-analgesic-effects-of-pulse-radiofrequency-and-cryoablation-in-rabbits-with-mental-nerve-neuropathic-pain
#5
D G Canpolat, E Soylu, F Dogruel, N Kütük, F Ugur
Purpose: After mental nerve injury, several sensory disorders may occur. The alterations in sensation may differ from mild paresthesia to complete anesthesia, or neuropathic pain. Neuropathic pain is a difficult clinical condition to manage. The aim of this study was to compare the analgesic effects of pulsed radiofrequency (PRF) and cryoablation in an experimental mental nerve neuropathic pain model in rabbits. Materials and Methods: Fifteen rabbits were divided into three groups...
May 2018: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29734509/efficacy-of-cryoablation-to-control-cancer-pain-a-systematic-review
#6
REVIEW
Laura Ferrer-Mileo, Ana Isabel Luque Blanco, Jesús González-Barboteo
CONTEXT: The use of opioids to control cancer pain could be insufficient. Interventional techniques such as a cryoablation have emerged as alternatives to opioids. OBJECTIVES: To summarize the current scientific evidence on the use of cryoablation to control cancer pain. METHODS: A systematic search of the Scopus, Pubmed, and Cochrane databases was performed. All articles published before December 31, 2015 whose title or abstract specified cancer pain control as endpoint were selected...
May 7, 2018: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/29734432/a-thermal-protective-urethral-heater-applied-to-modulate-the-prostate-cryoablation-area
#7
B Qian, H Zhao, B Xu, M Lan
BACKGROUND: Urethral warmer and cryoheater are invented and applied in cryoablation to overcome urethral cryoinjury, but these devices cannot be fixed and precisely control the released heat which excessively reduces the effective ablation area. Current warmers enlarge the operation difficulty and decrease the precision in temperature control. OBJECTIVE: A reformed catheter termed urethral heater aims to protect the urethra and simultaneously control the released heat so as to meet the aid of doctors' convenient operation in effective therapy, device fixation and precise heat controllability...
July 2017: Cryo Letters
https://www.readbyqxmd.com/read/29730348/epicardial-intraoperative-3-d-mapping-of-wolff-parkinson-white-in-a-child-with-ebstein-s-anomaly
#8
James C Perry, Andras Bratincsak, Suzanne Shepard, Matthew R Williams, Joseph Loslo, Raghav Murthy, John J Lamberti
Catheter ablation of arrhythmias in small patients has inherent significant risk due to patient, catheter, and lesion size. Heart block, perforation and coronary damage may occur. This report shows adaptation of a 3-D electroanatomic mapping system for intraoperative use in a small patient with Ebstein's anomaly undergoing Cone procedure and bidirectional Glenn. Use of this technique gave clear identification of the epicardial insertion points of two accessory pathways causing Wolff-Parkinson-White and resistant episodes of supraventricular tachycardia...
May 3, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29721503/radiofrequency-versus-cryoballoon-ablation-of-atrial-fibrillation-an-evaluation-using-ecg-holter-monitoring-and-implantable-loop-recorders-to-monitor-absolute-and-clinical-effectiveness
#9
Karapet Davtyan, Victoria Shatakhtsyan, Hermine Poghosyan, Alexandr Deev, Alexey Tarasov, Maria Kharlap, Svetlana Serdyuk, Georgy Simonyan, Sergey Boytcov
Introduction: While several studies have compared the radiofrequency current (RFC) and cryoablation for the treatment of patients with atrial fibrillation (AF), no study has monitored the long-term outcomes with the usage of implantable loop recorders (ILRs). Methods: We enrolled 89 consecutive patients with nonvalvular paroxysmal AF ( N = 44 for RFC and N = 45 for cryoballoon). The primary efficacy end point was the assessment of effectiveness for each group (RFC versus cryoballoon) when examining freedom from arrhythmia by monitoring with ECG, Holter, and implantable loop recoder (ILR)...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29721116/ventricular-tachycardia-storm-originating-from-interventricular-septum-successfully-treated-with-surgical-cryoablation-with-electroanatomic-and-electrophysiological-mapping-before-dual-valve-replacement
#10
Iwanari Kawamura, Seiji Fukamizu, Satoshi Miyazawa, Rintaro Hojo, Fusahiko Ito, Masazumi Watanabe, Mitsuhiro Nishizaki, Harumizu Sakurada, Masayasu Hiraoka
A 58-year-old man with dilated cardiomyopathy was admitted with heart failure. He had a history of two catheter ablation procedures for ventricular tachycardia (VT) originating from the intraventricular septum (IVS). Before dual valve replacement (DVR), he suffered a VT storm. An electrophysiological study revealed an extended low-voltage area at the IVS with the exit of the induced VT at the anterior side. Radiofrequency application was performed at the VT exit as a landmark for surgical cryoablation (SA)...
February 2018: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29720850/diagnosis-and-treatment-of-superficial-esophageal-cancer
#11
REVIEW
Maximilien Barret, Frédéric Prat
Endoscopy allows for the screening, early diagnosis, treatment and follow up of superficial esophageal cancer. Endoscopic submucosal dissection has become the gold standard for the resection of superficial squamous cell neoplasia. Combinations of endoscopic mucosal resection and radiofrequency ablation are the mainstay of the management of Barrett's associated neoplasia. However, protruded, non-lifting or large lesions may be better managed by endoscopic submucosal dissection. Novel ablation tools, such as argon plasma coagulation with submucosal lifting and cryoablation balloons, are being developed for the treatment of residual Barrett's esophagus, since iatrogenic strictures still hamper the development of extensive circumferential resections in the esophagus...
May 2018: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29704738/case-report-metastases-in-a-low-stage-middle-graded-hcc-in-cleared-hcv-infection-non-cirrhotic-liver-surgical-therapy
#12
Stefania Brozzetti, Simone Bini, Katia Fazzi, Leonardo Luca Chiarella, Virginia Ceccarossi, Chiara De Lucia, Giorgio De Toma
INTRODUCTION: Hepatocellular carcinoma (HCC) is rare in non-cirrhotic liver. Achievement of sustained virological response (SVR) reduces even more the risk. PRESENTATION OF CASE: Liver resection for small HCC was performed in cleared HCV infection non-cirrhotic 62-year-old man. Methacronous oligometastatic recurrences in intolerant to Nexavar® side-effects patient, were treated by multiple innovative microinvasive approaches: bilateral laparoscopic adrenalectomy, thoracic wall resection, laparoscopic sacrum cryoablation combined with hadron-therapy...
April 22, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29701425/analgesia-management-for-mitral-valve-repair-via-minithoracotomy-a-case-report
#13
Andreia Fernandes, Clara Gaio Lima, Nelson Paulo, Catarina Celestino, Ana Fonte Boa, Fátima Lima, Manuela Vieira
INTRODUCTION: Minimally invasive cardiac surgery (MICS), via minithoracotomy, is thought to be a fast track to extubation and recovery after surgery. Chronic pain, due to intercostal nerve injury, develops in up to 50% of postthoracotomy patients.A number of regional anaesthesia and analgesia techniques may be employed, and the anaesthesiologists play a key role in facilitating optimal outcomes after surgery. METHODS: We report a case of postoperative pain management with a local anesthetic infiltration for MICS...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29687867/cryoablation-for-atrial-fibrillation-and-antiarrhythmic-drug-pretreatment-a-single-referral-center-experience
#14
M Spartalis, E Tzatzaki, E Spartalis, D Moris, I Doulamis, A S Triantafyllis, E Livanis, G Theodorakis
OBJECTIVE: Pulmonary vein isolation (PVI) ablation has emerged as the gold standard of ablative strategies to treat medically refractory paroxysmal and persistent atrial fibrillation (AF). Regardless of the superiority of catheter ablation based on PVI over antiarrhythmic drug therapy, recurrence rates of AF remain higher than desired. PVI via cryoablation has rapidly become a mainstream treatment for AF, due to its effectiveness and fast learning curve. Our objective was to assess the safety and efficacy of cryoablation in a single referral center...
April 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29682611/unilateral-renal-tumor-cryoablation-and-contralateral-radical-nephrectomy-of-bilateral-renal-tumors-by-transumbilical-3d-multichannel-laparoendoscopic-single-site-surgery
#15
Guopeng Yu, Ke Zhang, Wenzhi Li, Long Li, Yanliang Zhao, Yiwei Wang, Mingxi Xu, Jun Da, Guoqin Dong, Zhong Wang, Bin Xu
Background: Unilateral renal tumor cryoablation and contralateral radical nephrectomy of bilateral renal tumors were performed by transumbilical three-dimensional (3D) multichannel laparoendoscopic single-site (LESS) surgery, in an attempt to verify the feasibility and safety of the procedure, sum up the operational experience, and evaluate the surgical outcome. Case Presentation: This was a 47-year-old female patient with a body mass index of 27.34 kg/m2 without backache, low back pain, hematuria, urinary urgency, frequent urination, dysuria, and other symptoms...
2018: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29680230/percutaneous-ablative-cryoimmunotherapy-for-micrometastaic-abscopal-effect-no-complications
#16
Erik Soule, Mark Bandyk, Jerry Matteo
Recent studies have shown efficacy of nivolumab, a monoclonal antibody specific for an immunoregulatory protein termed programmed death 1 (PD-1), against metastatic renal cell carcinoma. PD-1 is a transmembrane protein expressed on T cells that suppresses activation upon binding to its ligands, which may be secreted paraneoplastically by various cancers. Inhibition of PD-1 signaling via nivolumab may sensitize tumor-specific T lymphocytes in the immunosuppressive tumor microenvironment. Systemic elimination of micrometastases requires robust activation and proliferation of tumor antigen stimulated T cells...
April 19, 2018: Cryobiology
https://www.readbyqxmd.com/read/29679550/ct-guided-percutaneous-cryoablation-for-palliative-therapy-of-gastric-cancer-liver-metastases
#17
Xu Chang, Yan Wang, Hai-Peng Yu, Wei-Hao Zhang, Xue-Ling Yang, Zhi Guo
OBJECTIVE: Liver metastases occur in approximately 4%-14% of gastric cancer patients and are associated with high mortality. However, no standardized treatment approach is available for these patients. We aimed to assess the clinical outcomes of patients with gastric cancer liver metastases (GCLM) who underwent percutaneous cryoablation. METHODS: We retrospectively enrolled 19 patients with 27 metastatic hepatic tumors who underwent cryoablation for liver metastases after gastrectomy for primary gastric cancer...
April 18, 2018: Cryobiology
https://www.readbyqxmd.com/read/29677868/re-renal-functional-outcomes-in-patients-undergoing-percutaneous-cryoablation-or-partial-nephrectomy-for-a-solitary-renal-mass
#18
Jeffrey A Cadeddu
No abstract text is available yet for this article.
May 2018: Journal of Urology
https://www.readbyqxmd.com/read/29672193/cryoanalgesia-in-patients-undergoing-nuss-repair-of-pectus-excavatum-technique-modification-and-early-results
#19
Nicole Morikawa, Nicole Laferriere, Sylvia Koo, Sidney Johnson, Russell Woo, Devin Puapong
PURPOSE: The Nuss procedure for surgical correction of pectus excavatum often causes severe postoperative pain. Cryoanalgesia of intercostal nerves is an alternative modality for pain control. We describe our modification of the cryoICE™ probe that allows for nerve ablation through the ipsilateral chest along with early results utilizing this technique. METHODS: To allow for ipsilateral nerve ablation, a 20-French chest tube was cut and secured to the cryoICE probe, thus providing insulation for the malleable end of the probe...
April 19, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29667208/the-use-of-cardiac-ct-alone-to-exclude-left-atrial-thrombus-before-atrial-fibrillation-ablation-efficiency-safety-and-cost-analysis
#20
Wassim Mosleh, Ali Sheikh, Zaid Said, Mohamed A Abdel-Aal, Siri Gadde, Tanvi Shah, Michael F Wilson, Hiroko Beck, Chee Kim, Umesh C Sharma
BACKGROUND: Atrial fibrillation (AF) is a growing financial burden on the healthcare system. Cardiac computed tomographic angiography (CCTA) is needed for pulmonary vein mapping before AF ablation (AFA). CCTA has shown to be an alternative to transesophageal echocardiogram (TEE) to rule-out left atrial appendage thrombus (LAAT) pre-AFA. We aim to examine the safety, cost-effectiveness, and time-efficiency of utilizing CCTA alone to rule out LAAT before AFA. METHODS: We prospectively screened patients with paroxysmal AF undergoing cryoablation...
April 17, 2018: Pacing and Clinical Electrophysiology: PACE
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