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Catheter Related bloodstream infections

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https://www.readbyqxmd.com/read/29352697/venous-ports-in-infants
#1
Michael Acord, Anne Marie Cahill, Ganesh Krishnamurthy, Seth Vatsky, Marc Keller, Abhay Srinivasan
PURPOSE: To evaluate technical success and the incidences of, and risk factors for, mechanical and infectious complications of venous port placement in infants. MATERIALS AND METHODS: This was a retrospective single-institution cohort study of port placement in infants (age < 1 y) from January 2006 through June 2016 (mean age, 7.5 mo ± 3.3; mean weight, 8.1 kg ± 1.9). Age, weight, sex, side of placement, tip position, and indication for placement (chemotherapy vs other) were recorded...
January 15, 2018: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29340455/central-venous-catheter-related-infections-in-patients-receiving-short-term-hemodialysis-therapy-incidence-associated-factors-and-microbiological-aspects
#2
Mayra Gonçalves Menegueti, Natália Cristina Betoni, Fernando Bellissimo-Rodrigues, Elen Almeida Romão
INTRODUCTION: Bloodstream infections are the second most common cause of death among patients on hemodialysis. This study aimed to evaluate the incidence of and risk factors associated with central venous catheter-related infections in patients undergoing hemodialysis, and to identify and characterize the type and antimicrobial susceptibility profiles of the primary microorganisms isolated during one year of follow-up. METHODS: A prospective cohort study was conducted in 2014 in a hemodialysis referral center...
November 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29330016/clinical-impact-of-delayed-catheter-removal-for-patients-with-central-venous-catheter-related-gram-negative-bacteremia
#3
Yu-Mi Lee, Chisook Moon, Young Jin Kim, Hee-Joo Lee, Mi Suk Lee, Ki-Ho Park
BACKGROUND: Gram-negative bacteria are increasingly the cause of catheter-related bloodstream infections (CRBSI), which show a rapidly rising prevalence of multidrug-resistant strains. We evaluated the impact of delayed central venous catheter (CVC) removal on clinical outcomes in patients with gram-negative CRBSI. METHODS: Between January 2007 and December 2016, patients with gram-negative bacteremia and CVC placement, from two tertiary care hospitals, were retrospectively included...
January 9, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29322352/supraclavicular-catheterization-of-the-brachiocephalic-vein-a-way-to-prevent-or-reduce-catheter-maintenance-related-complications-in-children
#4
Flora Habas, Julien Baleine, Christophe Milési, Clémentine Combes, Marie-Noëlle Didelot, Sara Romano-Bertrand, Delphine Grau, Sylvie Parer, Catherine Baud, Gilles Cambonie
Placement of a central venous catheter (CVC) in the brachiocephalic vein (BCV) via the ultrasound (US)-guided supraclavicular approach was recently described in children. We aimed to determine the CVC maintenance-related complications at this site compared to the others (i.e., the femoral, the subclavian, and the jugular). We performed a retrospective data collection of prospectively registered data on CVC in young children hospitalized in a pediatric intensive care unit (PICU) during a 4-year period (May 2011 to May 2015)...
January 10, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29321722/distinct-virulent-network-between-healthcare-and-community-associated-staphylococcus-aureus-based-on-proteomic-analysis
#5
Lei He, Hongwei Meng, Qian Liu, Mo Hu, Yanan Wang, Xiaoying Chen, Xiaoyun Liu, Min Li
Background: Staphylococcus aureus (S. aureus or SA) is a leading cause of healthcare-associated (HA-) and community-associated (CA) infection. HA-SA isolates usually cause nosocomial pneumonia, bloodstream infections, catheter-related urinary tract infections, etc. On the other hand, CA-SA isolates usually cause highly fatal diseases, such as SSTIs as well as post influenza necrotic hemorrhagic pneumonia. The differences of the infection types are partially due to the unique characteristics between HA-SA and CA-SA isolates...
2018: Clinical Proteomics
https://www.readbyqxmd.com/read/29307014/stenotrophomonas-maltophilia-bacteremia-and-pneumonia-at-a-tertiary-care-oncology-center-a-review-of-16%C3%A2-years
#6
Consuelo Velázquez-Acosta, Sugehily Zarco-Márquez, Mari Carmen Jiménez-Andrade, Patricia Volkow-Fernández, Patricia Cornejo-Juárez
PURPOSE: The aim of this study was to describe the clinical characteristics and antimicrobial patterns of Stenotrophomonas maltophilia bloodstream infections (BSI) and pneumonia episodes in patients with cancer. METHODS: Patients with S. maltophilia BSI or pneumonia admitted from 1 Jan. 2000 to 31 Dec. 2016 were identified at the Instituto Nacional de Cancerología (INCan), a tertiary-care oncology hospital in Mexico City. RESULTS: During the study period, there were 171 isolates identified...
January 7, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29290346/predictive-factors-of-catheter-related-bloodstream-infection-in-patients-receiving-home-parenteral-nutrition
#7
Orawan Pichitchaipitak, Sineenuch Ckumdee, Siriluk Apivanich, Darunee Chotiprasitsakul, Prapimporn Chattranukulchai Shantavasinkul
OBJECTIVES: The aim of this study was to determine the incidence and predictive factors of catheter-related bloodstream infections (CRBSIs) acquired through a central venous catheter for delivery of home parenteral nutrition (HPN) therapy among a patient population in Thailand. METHODS: This retrospective review was conducted with adult patients with intestinal failure who received HPN from October 2002 to April 2014, at Ramathibodi Home Parenteral and Enteral Nutrition Referral Center in Bangkok...
February 2018: Nutrition
https://www.readbyqxmd.com/read/29289933/study-protocol-for-a-multicentre-randomised-controlled-trial-to-assess-the-effectiveness-of-antimicrobial-central-venous-catheters-versus-ordinary-central-venous-catheters-at-reducing-catheter-related-infections-in-critically-ill-chinese-patients
#8
Minming Wu, Yao Chen, Bin Du, Yan Kang
INTRODUCTION: Catheter use is associated with many complications and is an iatrogenic source of morbidity and mortality in intensive care units (ICU). The catheter being studied (Certofix Protect) was developed to reduce the risk of catheter related infections. This clinical trial will compare the safety and efficiency of Certofix Protect with that of an ordinary Certofix catheter. METHODS AND ANALYSIS: In this multicentre trial, we will randomly assigned dual lumen central venous catheterisation (≥5 ds) in patients in the adult ICU to the antimicrobial central venous catheter (CVC) group or the ordinary CVC group...
December 29, 2017: BMJ Open
https://www.readbyqxmd.com/read/29248964/prevention-of-hospital-infections-by-intervention-and-training-prohibit-results-of-a-pan-european-cluster-randomized-multicentre-study-to-reduce-central-venous-catheter-related-bloodstream-infections
#9
Tjallie van der Kooi, Hugo Sax, Didier Pittet, Jaap van Dissel, Birgit van Benthem, Bernhard Walder, Vanessa Cartier, Lauren Clack, Sabine de Greeff, Martin Wolkewitz, Stefanie Hieke, Hendriek Boshuizen, Jan van de Kassteele, Annemie Van den Abeele, Teck Wee Boo, Magda Diab-Elschahawi, Uga Dumpis, Camelia Ghita, Susan FitzGerald, Tatjana Lejko, Kris Leleu, Mercedes Palomar Martinez, Olga Paniara, Márta Patyi, Paweł Schab, Annibale Raglio, Emese Szilágyi, Mirosław Ziętkiewicz, Albert W Wu, Hajo Grundmann, Walter Zingg
PURPOSE: To test the effectiveness of a central venous catheter (CVC) insertion strategy and a hand hygiene (HH) improvement strategy to prevent central venous catheter-related bloodstream infections (CRBSI) in European intensive care units (ICUs), measuring both process and outcome indicators. METHODS: Adult ICUs from 14 hospitals in 11 European countries participated in this stepped-wedge cluster randomised controlled multicentre intervention study. After a 6 month baseline, three hospitals were randomised to one of three interventions every quarter: (1) CVC insertion strategy (CVCi); (2) HH promotion strategy (HHi); and (3) both interventions combined (COMBi)...
December 16, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/29248382/risk-factors-for-nosocomial-infections-after-cardiac-surgery-in-newborns-with-congenital-heart-disease
#10
Heladia García, Beatriz Cervantes-Luna, Héctor González-Cabello, Guadalupe Miranda-Novales
BACKGROUND: Congenital heart diseases are among the most common congenital malformations. Approximately 50% of the patients with congenital heart disease undergo cardiac surgery. Nosocomial infections (NIs) are the main complications and an important cause of increased morbidity and mortality associated with congenital heart diseases. This study's objective was to identify the risk factors associated with the development of NIs after cardiac surgery in newborns with congenital heart disease...
November 23, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29242058/endovascular-cooling-versus-standard-femoral-catheters-and-intravascular-complications-a-propensity-matched-cohort-study
#11
Olivier Andremont, Damien du Cheyron, Nicolas Terzi, Cedric Daubin, Amélie Seguin, Xavier Valette, Flore-Anne Lecoq, Jean-Jacques Parienti, Bertrand Sauneuf
BACKGROUND: Targeted temperature management (TTM) contributes to improved neurological outcome in adults who have been successfully resuscitated after cardiac arrest with shockable rhythm. Endovascular cooling catheters are widely used to induce and maintain targeted temperature in the ICU. The aim of the study was to compare the risk of complications with cooling catheters and standard central venous catheters. MATERIALS AND METHODS: In this prospective single-centre cohort study, we included all patients admitted to an intensive care unit for successfully resuscitated cardiac arrest that required endovascular TTM (Coolgard®, Zoll™ Medical corporation, MA, USA), between August 2012 and November 2014, inclusive...
December 11, 2017: Resuscitation
https://www.readbyqxmd.com/read/29227744/molecular-epidemiology-of-klebsiella-pneumoniae-strains-causing-bloodstream-infections-in-adults
#12
Meritxell Cubero, Imma Grau, Fe Tubau, Román Pallarés, M Ángeles Domínguez, Josefina Liñares, Carmen Ardanuy
Molecular epidemiology of Klebsiella pneumoniae bacteremic strains allows for a better understanding of preventive and therapeutic strategies. Clinical and microbiological characteristics of 348 K. pneumoniae bacteremia cases (2007-2009) were retrospectively characterized by multilocus sequence typing and extended-spectrum beta-lactamases (ESBL) production. Overall, 223 (64.08%) cases were nosocomial (NA), 58 (16.67%) healthcare associated, and 67 (19.25%) community acquired. The main infection origins were urinary tract (16...
December 11, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/29224997/in-vitro-assessment-of-the-anti-biofilm-activity-of-ethanol-alone-and-in-combination-with-enoxaparin-60iu
#13
María Jesús Pérez-Granda, Beatriz Alonso, Ana Rodríguez-Huerta, Carmen Rodríguez, María Guembe
INTRODUCTION: Catheter-related bloodstream infection (C-RBSI) can sometimes be managed without catheter removal by combining systemic therapy with catheter lock therapy. Most antiseptic lock solutions are made up of ethanol combined with an anticoagulant. However, data regarding the anti-biofilm activity of ethanol combined with enoxaparin are scarce. We aimed to assess the efficacy of ethanol at different concentrations combined with enoxaparin 60IU as a lock solution for eradication of the biofilm of different microorganisms...
December 7, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29216782/reduction-in-central-line-associated-bloodstream-infections-correlated-with-the-introduction-of-a-novel-silver-plated-dressing-for-central-venous-catheters-and-maintained-for-6-years
#14
Rachel Karlnoski, Elia Charbel Abboud, Peggy Thompson, Asa Z Oxner, John T Sinnott, Jorge E Marcet
OBJECTIVE: To assess a novel silver-plated dressing (SD) for central venous catheters in comparison to chlorhexidine gluconate-impregnated sponge (CHGIS) dressings in preventing central line-associated bloodstream infections (CLABSIs) in adult intensive care unit (ICU) patients. DESIGN: Retrospective cohort study. SETTING: Tampa General Hospital, an academic medical tertiary care center. PATIENTS: All adult ICU patients of an academic medical tertiary care center from January 2009 to December 2010...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29214504/postmarketing-experience-with-neutrolin%C3%A2-taurolidine-heparin-calcium-citrate-catheter-lock-solution-in-hemodialysis-patients
#15
Bruce E Reidenberg, Christoph Wanner, Bruce Polsky, Mariana Castanheira, Alla Shelip, Dirk Stalleicken, Antony E Pfaffle
Catheter-related bloodstream infections (CRBSI) are major complications for patients with life-threatening conditions requiring chronic vascular catheterization. The wide range of etiologic microbes and the ongoing development of resistance to antimicrobials with specific mechanisms of action make this an appropriate target for applying a nonspecific antimicrobial therapeutic. Taurolidine hydrolyzes into two antimicrobial moieties, formaldehyde and methylene glycol, which react with microbial surfaces. Neutrolin® (taurolidine, heparin, calcium citrate) was recently introduced in Germany as an antimicrobial catheter lock solution...
December 6, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29212442/impact-of-inappropriate-antifungal-therapy-according-to-current-susceptibility-breakpoints-on-candida-bloodstream-infection-mortality-a-retrospective-analysis
#16
María Fernanda González-Lara, Pedro Torres-González, Patricia Cornejo-Juárez, Consuelo Velázquez-Acosta, Areli Martinez-Gamboa, Andrea Rangel-Cordero, Miriam Bobadilla-Del-Valle, Luis Ostrosky-Zeichner, Alfredo Ponce-de-León, José Sifuentes-Osornio
BACKGROUND: The mortality of Candida Bloodstream Infection (CBSI) remains high. Antifungal susceptibility breakpoints were recently updated for Candida species, the impact remains unknown. In this study we evaluated the impact of inappropriate antifungal treatment according to recent breakpoints on 30-day mortality of CBSI. METHODS: From June 2008 to July 2014, data on CBSI episodes from two tertiary-care centers, treated > 72 h were analyzed. Antifungal therapy and 30-day mortality were registered...
December 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29211248/draft-genome-of-the-emerging-pathogen-kocuria-marina-isolated-from-a-wild-urban-rat
#17
Shih Keng Loong, Kim-Kee Tan, Nurhafiza Zainal, Wai Hong Phoon, Siti Nursheena Mohd Zain, Sazaly AbuBakar
Kocuria marina has recently emerged as a cause for catheter-related bloodstream infections in patients with underlying health complications. One K. marina strain was recently isolated from the lung tissues of a wild urban rat (Rattus rattus diardii) caught during rodent surveillance. Here, we present the draft genome of the first K. marina animal isolate, K. marina TRE150902.
December 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/29211195/impact-of-two-bundles-on-central-catheter-related-bloodstream-infection-in-critically-ill-patients
#18
Cristobal Felipe Padilla Fortunatti
OBJECTIVE: To evaluate the impact of the implementation of insertion and maintenance bundles on the rates of catheter-related bloodstream infection in an intensive care unit. METHOD: This is a quasi-experimental, before-and-after study with a non-equivalent control group. During a six-month period, insertion and maintenance bundles for the central venous catheters were implemented. Supervision guidelines were developed to assess compliance with the bundle and catheter characteristics...
December 4, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/29198897/the-idle-central-venous-catheter-in-the-nicu-when-should-it-be-removed
#19
Cristen N Litz, Jordan G Tropf, Paul D Danielson, Nicole M Chandler
PURPOSE: There is debate regarding the optimal timing of central line removal in the neonatal intensive care unit (NICU). The purpose was to evaluate outcomes of idle peripherally inserted central catheters (PICCs) and tunneled central venous catheters (TCVCs) and determine the incidence of line-related infections and replacements. METHODS: Patients in the NICU with T-CVCs placed between 11/2008 and 8/2015 (n=134) or PICCs placed between 7/2013 and 10/2015 (n=467) were included...
November 9, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29189981/healthcare-associated-bloodstream-infections-in-polish-hospitals-prevalence-epidemiology-and-microbiology-summary-data-from-the-ecdc-point-prevalence-survey-of-healthcare-associated-infections-2012-2015
#20
Aleksander Deptuła, Ewa Trejnowska, Grzegorz Dubiel, Monika Wanke-Rytt, Maria Deptuła, Waleria Hryniewicz
Aggregated data from the Polish Point Prevalence Survey of Healthcare Associated Infections and Antimicrobial Use (PPS HAI&AU) collected between 2012 and 2015 were used to describe the epidemiology of healthcare associated bloodstream infections (BSI) in Polish hospitals, in order to assess the rationale for introducing a BSI surveillance programme in our country and analyse selected risk factors. Data were collected according to the ECDC PPS HAI&AU protocol. Within four years, records for 71,039 patients were collected in 36 (2012), 32 (2013), 112 (2014), and 158 (2015) hospitals; representativeness was evaluated as good in 2012-2013, and excellent from 2014...
November 30, 2017: European Journal of Clinical Microbiology & Infectious Diseases
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