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Catheter Related bloodstream infections

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https://www.readbyqxmd.com/read/28630243/quad-fever-beware-of-non-infectious-fever-in-high-spinal-cord-injuries
#1
Jyoti Goyal, Rakesh Jha, Paramjeet Bhatia, Raj Kumar Mani
A case of cervical spinal cord injury and quadriparesis with prolonged fever is being described. Initially, the patient received treatment for well-documented catheter-related bloodstream infection. High spiking fever returned and persisted with no obvious evidence of infection. The usual non-infectious causes too were carefully excluded. QUAD fever or fever due to spinal cord injury itself was considered. The pathogenetic basis of QUAD fever is unclear but could be attributed to autonomic dysfunction and temperature dysregulation...
June 18, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28623882/peripheral-venous-catheter-related-bloodstream-infection-is-associated-with-severe-complications-and-potential-death-a-retrospective-observational-study
#2
Akihiro Sato, Itaru Nakamura, Hiroaki Fujita, Ayaka Tsukimori, Takehito Kobayashi, Shinji Fukushima, Takeshi Fujii, Tetsuya Matsumoto
BACKGROUND: The purpose of this study was to identify the clinical characteristics and outcomes of peripheral vascular catheter-related bloodstream infections (PVC-BSIs) and determine the risk of severe complications or death. METHODS: We performed a retrospective observational study from June 2010 to April 2015 at two regional university-affiliated hospitals in Tokyo. We studied the clinical manifestations, underlying diseases, laboratory results, treatment methods, recurrence rates, and complications in 62 hospitalized patients diagnosed with PVC-BSIs by positive blood cultures...
June 17, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28623661/graphene-nanolayers-as-a-new-method-for-bacterial-biofilm-prevention-preliminary-results
#3
Łucja Dybowska-Sarapuk, Andrzej Kotela, Jakub Krzemiński, Marta Wróblewska, Halina Marchel, Magdalena Romaniec, Paweł Łęgosz, Małgorzata Jakubowska
Biofilms are microbial communities of surface-attached cells embedded in a self-produced extracellular matrix. They have been found to play a role in a wide variety of infections, including catheter-related urinary tract and bloodstream infections, and, therefore remain a significant source of morbidity and mortality among the world's population. Recently, much attention has been devoted to the prevention of biofilm formation on implant surfaces. Nanomaterials such as graphene, characterized by antibacterial activity and low toxicity to human cells, are promising candidates for biomedical applications...
June 16, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28622231/catheter-related-bloodstream-infection-in-jugular-versus-subclavian-central-catheterization
#4
Jean-Jacques Parienti
No abstract text is available yet for this article.
July 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28619777/peripherally-inserted-central-catheter-dressing-and-securement-in-patients-with-cancer-the-pisces-trial-protocol-for-a-2x2-factorial-superiority-randomised-controlled-trial
#5
Claire M Rickard, Nicole M Marsh, Joan Webster, Nicole C Gavin, Raymond J Chan, Alexandra L McCarthy, Peter Mollee, Amanda J Ullman, Tricia Kleidon, Vineet Chopra, Li Zhang, Matthew R McGrail, Emily Larsen, Md Abu Choudhury, Samantha Keogh, Evan Alexandrou, David J McMillan, Merehau Cindy Mervin, David L Paterson, Marie Cooke, Gillian Ray-Barruel, Maria Isabel Castillo, Andrew Hallahan, Amanda Corley, E Geoffrey Playford
INTRODUCTION: Around 30% of peripherally inserted central catheters (PICCs) fail from vascular, infectious or mechanical complications. Patients with cancer are at highest risk, and this increases morbidity, mortality and costs. Effective PICC dressing and securement may prevent PICC failure; however, no large randomised controlled trial (RCT) has compared alternative approaches. We designed this RCT to assess the clinical and cost-effectiveness of dressing and securements to prevent PICC failure...
June 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28598310/in-vitro-activities-of-vancomycin-and-linezolid-against-biofilm-producing-methicillin-resistant-staphylococci-species-isolated-from-catheter-related-bloodstream-infections-from-an-egyptian-tertiary-hospital
#6
Asmaa A Hashem, Noha M Abd El Fadeal, Atef S Shehata
PURPOSE: Catheter-related bloodstream infections (CRBSIs) are among the most common hospital-acquired infections. We aimed to survey methicillin resistance, biofilm production and susceptibility to vancomycin, linezolid and other antibiotics for staphylococci isolated from CRBSIs. METHODOLOGY: Fifty-eight isolates [20 S. aureus and 38 coagulase-negative staphylococci (CoNS; 20 Staphylococcusepidermidis, nine Staphylococcushaemolyticus, three Staphylococcusschleiferi, two Staphylococcuswarneri and four Staphylococcuslugdunensis)] were tested for methicillin resistance by cefoxitin disk diffusion and detection of the mecA gene by PCR; biofilm-forming ability using Congo red agar and tissue culture plate methods; susceptibility to ciprofloxacin, clindamycin, cotrimoxazole, erythromycin, gentamicin, linezolid, rifampicin and tetracycline; and MIC determination for vancomycin...
June 9, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28596019/risk-factors-of-catheter-related-bloodstream-infection-caused-by-bacillus-cereus-case-control-study-in-8-teaching-hospitals-in-japan
#7
Satoshi Kutsuna, Kayoko Hayakawa, Kazuya Kita, Yuichi Katanami, Natsuko Imakita, Kei Kasahara, Masami Seto, Kenichiro Akazawa, Minoru Shimizu, Toshikazu Kano, Takahito Nei, Tetsuro Hayashi, Nobuaki Mori, Taku Yabuki, Norio Ohmagari
In this multicenter, matched case-control study, patients diagnosed with catheter-related bloodstream infection (CRBSI) caused by Bacillus cereus (n = 108) were matched to controls (n = 269). In the multivariable analysis, administration of an amino acid preparation and an indwelling peripheral catheter were significant variables for B cereus-related CRBSI.
June 5, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28577734/-renal-replacement-therapy-for-acute-kidney-injury-in-the-intensive-care-unit
#8
Stéphane Gaudry, Khalil Chaïbi, Nicolas Bénichou, Charles Verney, David Hajage, Didier Dreyfuss
Renal replacement therapy for acute kidney injury has been used for more than 60 years. Except when life-threatening metabolic complications such as severe hyperkalaemia are present, renal replacement therapy initiation criteria are the subject of intense debate. Significant progress has been made with the publication of the AKIKI multicenter trial, which showed that a delayed renal replacement therapy initiation strategy (in the absence of life-threatening metabolic complications) was not associated with a difference in mortality compared to an early renal replacement therapy initiation strategy...
April 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28576557/a-prospective-double-blind-randomized-controlled-study-on-the-use-of-ethanol-locks-in-hpn-patients
#9
Bradley R Salonen, Sara L Bonnes, Nishanth Vallumsetla, Jithinraj Edakkanambeth Varayil, Manpreet S Mundi, Ryan T Hurt
BACKGROUND & AIMS: Ethanol lock therapy (ELT) has been shown to reduce the rate of catheter-related bloodstream infection (CRBSI) in high-risk home parenteral nutrition (HPN) patients. The aim of this study was to determine whether ELT therapy for all patients newly started on HPN would reduce the incidence of CRBSI. METHODS: This study was a prospective, double-blind, randomized controlled trial that was carried out from July 2014 to April 2016. The study participants were patients newly started on HPN, and they were randomly assigned to either treatment with ELT or our current standard of care with saline heparin locks...
May 17, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28558699/incidence-of-and-factors-associated-with-catheter-related-bloodstream-infection-in-patients-with-advanced-solid-tumors-on-home-parenteral-nutrition-managed-using-a-standardized-catheter-care-protocol
#10
Pankaj G Vashi, Natasha Virginkar, Brenten Popiel, Persis Edwin, Digant Gupta
BACKGROUND: Catheter-related bloodstream infections (CRBSIs) are associated with high morbidity and mortality as well as increased medical costs. Cancer patients, who are often immunocompromised, are susceptible to CRBSI while receiving home parenteral nutrition (HPN). We evaluated the incidence of and factors associated with CRBSIs in cancer patients undergoing HPN managed using a standardized catheter care protocol. METHODS: This is a retrospective cohort study of 335 cancer patients receiving HPN between January 2012 and July 2015...
May 30, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28534703/chlorhexidine-and-silver-sulfadiazine-coating-on-central-venous-catheters-is-not-sufficient-for-protection-against-catheter-related-infection-simulation-based-laboratory-research-with-clinical-validation
#11
Yoon Ji Choi, Jae Kwan Lim, Jeong Jun Park, Hyub Huh, Dong-Joo Kim, Chang-Hoon Gong, Seung Zhoo Yoon
Objective The efficacy of chlorhexidine- and silver sulfadiazine-coated central venous catheters (CSS-CVC) against catheter-related infection remains controversial. We hypothesized that the loss of silver nanoparticles may reduce the antibacterial efficacy of CSS-CVCs and that this loss could be due to the frictional force between the surface of the CVC and the bloodstream. The objective of this study was to investigate whether the antimicrobial effect of CSS-CVCs decreases with increasing exposure time in a bloodstream model and quantitatively assay the antimicrobial effect of CSS-CVCs compared with polyurethane and antiseptic-impregnated CVCs...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28526171/chlorhexidine-gluconate-or-polyhexamethylene-biguanide-disc-dressing-to-reduce-the-incidence-of-central-line-associated-bloodstream-infection-a-feasibility-randomized-controlled-trial-the-clabsi-trial
#12
J Webster, E Larsen, N Marsh, A Choudhury, P Harris, C M Rickard
BACKGROUND: A number of antimicrobial-impregnated discs to prevent central-line-associated bloodstream infection (CLABSI) are marketed but it is unclear which disc is most effective. AIM: To investigate the feasibility and safety of comparing two antimicrobial-impregnated discs to prevent CLABSI. METHODS: A single-centre, parallel group, randomized controlled trial was conducted in a 929-bed tertiary referral hospital. Hospital inpatients requiring a peripherally inserted central catheter were randomized to chlorhexidine gluconate (CHG) or polyhexamethylene biguanide (PHMB) disc dressing group...
July 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28514979/determination-of-a-cutoff-time-point-for-prophylactic-exchange-of-central-venous-catheters-for-prevention-of-central-venous-catheter-related-bloodstream-infections-in-patients-with-hematological-malignancies
#13
Enrico Schalk, Lena M Biehl, Jacqueline Färber, Dirk Schlüter, Maria J G T Vehreschild, Thomas Fischer
No abstract text is available yet for this article.
May 18, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28509133/denosumab-for-treatment-of-immobilization-related-hypercalcemia-in-a-patient-with-end-stage-renal-disease
#14
Atsuko Uehara, Masahiko Yazawa, Atsumi Kawata, Rina Hachisuka, Yugo Shibagaki
The efficacy and safety of denosumab for the treatment of immobilization-related hypercalcemia in end-stage renal disease remain uncertain. We describe the case of a hemodialysis patient with immobilization-related hypercalcemia who was successfully treated with denosumab. A 79-year-old man admitted for hemodialysis after sustaining an acute kidney injury developed immobilization-related hypercalcemia due to the impairment resulting from an acute myocardial infarction, acute heart failure, and catheter-related bloodstream infection...
May 2017: CEN Case Reports
https://www.readbyqxmd.com/read/28502638/oncology-nurses-knowledge-of-guidelines-for-preventing-catheter-related-bloodstream-infections
#15
Mohammad Al Qadire
This descriptive cross-sectional survey evaluated Jordanian oncology nurses' knowledge of the guidelines for preventing central venous catheter-associated infection. Poor knowledge was evident from the very low mean total scores and the low percentage of correct answers for each item in the questionnaire.
May 11, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28478850/randomized-controlled-trial-of-care-bundles-with-chlorhexidine-dressing-and-advanced-dressings-to-prevent-catheter-related-bloodstream-infections-in-pediatric-hematology-oncology-patients
#16
Gülçin Özalp Gerçeker, Figen Yardımcı, Yeşim Aydınok
PURPOSE: To compare the effects of the care bundles including chlorhexidine dressing and advanced dressings on the catheter-related bloodstream infection (CRBSI) rates in pediatric hematology-oncology patients with central venous catheters (CVCs). METHOD: Twenty-seven PHO patients were recruited to participate in a prospective, randomized study in Turkey. The researcher used care bundles with chlorhexidine dressing in the experimental group (n = 14), and care bundles with advanced dressings in the control group (n = 13)...
June 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28475779/comparative-efficacy-of-antimicrobial-central-venous-catheters-in-reducing-catheter-related-bloodstream-infections-in-adults-abridged-cochrane-systematic-review-and-network-meta-analysis
#17
Huey Yi Chong, Nai Ming Lai, Anucha Apisarnthanarak, Nathorn Chaiyakunapruk
Background: The efficacy of antimicrobial central venous catheters (CVCs) remains questionable. In this network meta-analysis, we aimed to assess the comparative efficacy of antimicrobial CVC impregnations in reducing catheter-related infections in adults. Methods: We searched 4 electronic databases (Medline, the Cochrane Central Register of Controlled Trials, Embase, CINAHL) and internet sources for randomized controlled trials, ongoing clinical trials, and unpublished studies up to August 2016...
May 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28469510/a-study-of-use-of-port-catheter-in-patients-with-cancer-a-single-center-experience
#18
Irappa Madabhavi, Apurva Patel, Malay Sarkar, Asha Anand, Harsha Panchal, Sonia Parikh
BACKGROUND: Effective and reliable venous access is one of the cornerstones of modern medical therapy in oncology. MATERIALS AND METHODS: This is a prospective observational study, which collected data of patients who require "PORT" catheter insertion for any cancer, at a tertiary care oncology hospital in Ahmadabad, Gujarat, India, during a 2-year period. AIMS AND OBJECTIVES: The main objective of this study was to study the various complications and outcomes related to "PORT" catheters...
2017: Clinical Medicine Insights. Oncology
https://www.readbyqxmd.com/read/28453316/peripheral-intravenous-cannulation-protecting-patients-and-nurses
#19
Andrew Barton, Roy Ventura, Boris Vavrik
Peripheral intravenous cannulation is a common clinical procedure in today's healthcare setting. There are a range of different devices to choose from, and this article will consider the risk of catheter-related bloodstream infections and needlestick injuries, national and international guidelines on infection prevention and safety in intravenous access, the need for closed catheters, features of the Introcan Safety® 3 (B. Braun Melsungen AG) and research into peripheral cannulas.
April 27, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28448786/microbiological-features-and-clinical-impact-of-the-type-vi-secretion-system-t6ss-in-acinetobacter-baumannii-isolates-causing-bacteremia
#20
Jungok Kim, Ji-Young Lee, Haejeong Lee, Ji Young Choi, Dae Hun Kim, Yu Mi Wi, Kyong Ran Peck, Kwan Soo Ko
We investigated the genetic background and microbiological features of T6SS-positive Acinetobacter baumannii isolates and clinical impact of the T6SS in patients with A. baumannii bacteremia. One hundred and sixty-two A. baumannii isolates from patients with bacteremia in two tertiary-care hospitals in Korea were included in this study. Approximately one-third (51/162, 31.5%) of the A. baumannii clinical isolates possessed the hcp gene, and the hcp-positive isolates were found in several genotypes in multilocus sequence typing...
April 27, 2017: Virulence
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