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Catheter Related bloodstream infections

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https://www.readbyqxmd.com/read/27924201/central-line-associated-bloodstream-infections-in-the-intensive-care-unit-importance-of-the-care-bundle
#1
Aynur Atilla, Zahide Doğanay, Hale Kefeli Çelik, Leman Tomak, Özgür Günal, S Sırrı Kılıç
BACKGROUND: The importance and efficacy of a care bundle for preventing central line-associated bloodstream infections (CLABSIs) and infectious complications related to placing a central venous catheter (CVC) in patients in the intensive care unit (ICU). METHODS: A care bundle was implemented from July 2013 to June 2014 in a medical ICU and surgical ICU. Data were divided into three periods: the prior period (July 2012-June 2013), the intervention period (July 2013-June 2014; first and second periods), and the post-intervention period (July 2014-December 2014; third period)...
December 2016: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/27911152/non-tuberculous-mycobacterial-bloodstream-infections-in-patients-with-indwelling-vascular-catheters-the-role-of-sickle-cell-anaemia
#2
Babatunde Edun, Ansal Shah, Martin Durkin, Melanie Whitmire, Shanetta Patterson Williams, Helmut Albrecht, Majdi Al-Hasan, Sharon Weissman
INTRODUCTION: Few studies have examined risk factors for nontuberculous mycobacteria (NTM) bloodstream infections (BSI) involving indwelling vascular catheters (IDVC). Sickle cell anaemia (HbSS/SC) is known to affect several aspects of the immune system leading to relative immune deficiency. The purpose of this retrospective nested case-control study was to determine if HbSS/SC is a risk factor for NTM BSI among individuals with IDVCs. METHODS: All NTM IDVC infections (cases) at two tertiary hospitals from 2008 to 2014 were reviewed...
December 2, 2016: Infectious Diseases
https://www.readbyqxmd.com/read/27908954/chlorhexidine-impregnated-dressings-and-prevention-of-catheter-associated-bloodstream-infections-in-a-pediatric-intensive-care-unit
#3
Duygu Sönmez Düzkaya, Nejla Canbulat Sahiner, Gülzade Uysal, Tülay Yakut, Agop Çitak
BACKGROUND: Bloodstream infections related to use of catheters are associated with increased morbidity and mortality rates, prolonged hospital lengths of stay, and increased medical costs. OBJECTIVES: To compare the effectiveness of chlorhexidine-impregnated dressings with that of standard dressings in preventing catheter-related bloodstream infections. METHODS: A total of 100 children were randomly divided into 2 groups of 50 each: a chlorhexidine group and a standard group...
December 2016: Critical Care Nurse
https://www.readbyqxmd.com/read/27890335/device-associated-infections-in-a-paediatric-intensive-care-unit-in-pakistan
#4
A Haque, S A Ahmed, Z Rafique, Q Abbas, H Jurair, S A Ali
This study assessed the effect of implementation of active infection control and surveillance on the occurrence of device-associated infections (DAIs) in a paediatric intensive care unit (PICU) from 2012 to 2015. There were 1378 patients, equating to 4632 patient-days, on the PICU, and 29 DAI episodes, giving an incidence rate of 2.1% and an incidence density rate of 6.26 per 1000 patient-days. The rates of central-line-associated bloodstream infections, ventilator-associated pneumonia and catheter-related urinary tract infections were 7/1000 central-line-days, 1...
November 4, 2016: Journal of Hospital Infection
https://www.readbyqxmd.com/read/27875289/home-parenteral-nutrition-in-adult-patients-with-chronic-intestinal-failure-catheter-related-complications-over-4-decades-at-the-main-danish-tertiary-referral-center
#5
Christopher Filtenborg Brandt, Siri Tribler, Mark Hvistendahl, Rahim M Naimi, Per Brøbech, Michael Staun, Palle Bekker Jeppesen
BACKGROUND/AIMS: Catheter-related complications (CRCs) cause mortality and morbidity in patients dependent on parenteral support at home (HPN) due to intestinal failure (IF). This study describes the incidences of CRCs in an adult IF cohort over 40 years. It illustrates the evolution and consequences of CRCs, their association to demographic characteristics, and potential risk factors in an effort to provide the rationale for preventive precautions to the relevant patients with IF at risk...
November 15, 2016: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27872410/risk-of-mortality-of-catheter-related-bloodstream-infections-caused-by-acinetobacter-species-is-early-removal-of-the-catheters-associated-with-a-better-survival-outcome
#6
Yi Lee, Yi-Tzu Lee, Yung-Chih Wang, Chung-Ting Chen, Jun-Ren Sun, Chang-Pan Liu, Yuan-Meng Liu, Shu-Chen Kuo, Chun-Hsiang Chiu, Ya-Sung Yang, Jung-Chung Lin, Te-Li Chen
PURPOSE: Bloodstream infections (BSIs) caused by Acinetobacter species have been extensively reported, however, which majorly focused on respiratory tract infections. The risk of mortality and the effect of early catheter removal on survival in catheter-related BSIs (CRBSIs) caused by Acinetobacter spp. remain unclear. This study aims to investigate that. METHODS: This is a retrospective multicentric study conducted in Taiwan from 2012 to 2014. Patients with at least 1 positive blood culture and catheter culture for the same Acinetobacter spp...
November 20, 2016: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/27870104/clinical-experience-with-daptomycin-in-pediatrics
#7
Katie C Namtu, Julianna C Crain, Allison F Messina, Juan A Dumois, David M Berman
INTRODUCTION: The management of Gram-positive infections has been complicated in recent years by the emergence of antimicrobial resistance, leaving fewer options for therapy. Daptomycin is a lipopeptide antibiotic used for the systemic treatment of Gram-positive infections and has a distinct mechanism of action, favorable side effect profile, and requires once daily dosing. Unfortunately, there is a paucity of safety, efficacy, and pharmacokinetic data in neonatal and pediatric patients...
November 21, 2016: Pharmacotherapy
https://www.readbyqxmd.com/read/27846059/taurolidine-in-pediatric-home-parenteral-nutrition-patients
#8
Emma Claire Hulshof, Lidwien Marieke Hanff, Joanne Olieman, Susanna de Vette, Gert-Jan Driessen, Conny Meeussen, Johanna Caroline Escher
In order to reduce the incidence of catheter-related bloodstream infections (CRBSI) in home parenteral nutrition patients, the use of taurolidine was introduced in the Sophia Children's Hospital in 2011. This introduction led to a reduction in CRBSI: 12.7/1,000 catheter days before the use of taurolidine, compared with 4.3/1,000 catheter days afterwards (n=7) (relative risk=0.36, 95%CI: 0.20-0.65 (p= 0,018)).
November 11, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27816140/prevention-of-vascular-catheter-related-bloodstream-infections
#9
REVIEW
Mark E Rupp, Denisa Majorant
Catheter-related bloodstream infections (CRBSI) are responsible for significant morbidity, mortality, and excess health care costs. It is increasingly evident that many CRBSI can be prevented with current knowledge and techniques. Preventive measures can be broadly grouped into clinical practice-based interventions and technologic innovations. Clinical practice-based interventions require changes in human behavior and can be subdivided into interventions before and at the time of insertion and postinsertion...
December 2016: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/27807156/subcutaneous-infusion-of-fluids-for-hydration-or-nutrition-a-review
#10
REVIEW
Riccardo Caccialanza, Thierry Constans, Paolo Cotogni, Gary P Zaloga, Alessandro Pontes-Arruda
Subcutaneous infusion, or hypodermoclysis, is a technique whereby fluids are infused into the subcutaneous space via small-gauge needles that are typically inserted into the thighs, abdomen, back, or arms. In this review, we provide an overview of the technique, summarize findings from studies that have examined the use of subcutaneous infusion of fluids for hydration or nutrition, and describe the indications, advantages, and disadvantages of subcutaneous infusion. Taken together, the available evidence suggests that, when indicated, subcutaneous infusion can be effective for administering fluids for hydration or nutrition, with minimal complications, and has similar effectiveness and safety to the intravenous route...
November 2, 2016: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27788992/catheter-related-infections-in-patients-with-haematological-malignancies-novel-preventive-and-therapeutic-strategies
#11
REVIEW
Ramia Zakhour, Anne-Marie Chaftari, Issam I Raad
Central venous catheters are essential for the treatment of patients with haematological malignancies and the recipients of stem-cell transplant. This patient population is, however, at high risk for catheter-related bloodstream infections that can result in substantial morbidity, mortality, and health-care-associated costs. Efficient prevention, early diagnosis, and effective treatment are essential to providing the best care to these patients. Although confirming the catheter as a source of infection remains challenging, the Infectious Diseases Society of America definition of catheter-related bloodstream infection remains the most precise definition to use in these patients...
November 2016: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/27780607/ultrasound-guided-deep-arm-veins-insertion-of-long-peripheral-catheters-in-patients-with-difficult-venous-access-after-cardiac-surgery
#12
Adam Fabiani, Lorella Dreas, Gianfranco Sanson
OBJECTIVES: To analyze success rate, dwell-time, and complications of long peripheral venous catheters (L-PVCs) inserted under ultrasound guidance. BACKGROUND: In difficult venous access (DVA) patients, L-PVC can represent an alternative to central or midline catheters. METHODS: Prospective observational study. L-PVCs were positioned in DVA patients. The outcome of the cannulation procedure and the times and reasons for catheters removal were analyzed...
October 22, 2016: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/27775764/economic-evaluation-of-quality-improvement-interventions-for-bloodstream-infections-related-to-central-catheters-a-systematic-review
#13
Teryl K Nuckols, Emmett Keeler, Sally C Morton, Laura Anderson, Brian Doyle, Marika Booth, Roberta Shanman, Jonathan Grein, Paul Shekelle
Importance: Although quality improvement (QI) interventions can reduce central-line-associated bloodstream infections (CLABSI) and catheter-related bloodstream infections (CRBSI), their economic value is uncertain. Objective: To systematically review economic evaluations of QI interventions designed to prevent CLABSI and/or CRBSI in acute care hospitals. Evidence Review: A search of Ovid MEDLINE, Econlit, Centre for Reviews & Dissemination, New York Academy of Medicine's Grey Literature Report, Worldcat, prior systematic reviews (January 2004 to July 2016), and IDWeek conference abstracts (2013-2016), was conducted from 2013 to 2016...
December 1, 2016: JAMA Internal Medicine
https://www.readbyqxmd.com/read/27717604/healthcare-associated-gram-negative-bloodstream-infections-antibiotic-resistance-and-predictors-of-mortality
#14
Ö Ergönül, M Aydin, A Azap, S Başaran, S Tekin, Ş Kaya, S Gülsün, G Yörük, E Kurşun, A Yeşilkaya, F Şimşek, E Yılmaz, H Bilgin, Ç Hatipoğlu, H Cabadak, Y Tezer, T Togan, I Karaoğlan, A İnan, A Engin, H E Alışkan, S Ş Yavuz, Ş Erdinç, L Mulazimoglu, Ö Azap, F Can, H Akalın, F Timurkaynak
This article describes the prevalence of antibiotic resistance and predictors of mortality for healthcare-associated (HA) Gram-negative bloodstream infections (GN-BSI). In total, 831 cases of HA GN-BSI from 17 intensive care units in different centres in Turkey were included; the all-cause mortality rate was 44%. Carbapenem resistance in Klebsiella pneumoniae was 38%, and the colistin resistance rate was 6%. Multi-variate analysis showed that age >70 years [odds ratio (OR) 2, 95% confidence interval (CI) 1...
December 2016: Journal of Hospital Infection
https://www.readbyqxmd.com/read/27684636/clinical-application-of-prophylactic-ethanol-lock-therapy-in-pediatric-patients-with-intestinal-failure
#15
Sheila L Robbins Tighe
Patients with intestinal failure have an increased risk for catheter-related bloodstream infections that can necessitate central venous line replacement and result in morbidity, prolonged hospitalization, or mortality. For pediatric patients with intestinal failure, the severe loss of intestinal absorptive ability leads to reliance on parenteral nutrition to meet minimal needs required for growth and development. Reliance on parenteral nutrition, in turn, forces dependency on central venous lines. Recent research concentrating on the pediatric population with intestinal failure indicates that prophylactic ethanol lock therapy can reduce the rate of catheter-related bloodstream infections and decrease central venous line removal rates in this high-risk population...
September 2016: Gastroenterology Nursing: the Official Journal of the Society of Gastroenterology Nurses and Associates
https://www.readbyqxmd.com/read/27666952/risk-factors-for-central-line-associated-bloodstream-infection-in-pediatric-oncology-patients-with-a-totally-implantable-venous-access-port-a-cohort-study
#16
Michelle Ribeiro Viana Taveira, Luciana Santana Lima, Cláudia Corrêa de Araújo, Maria Júlia Gonçalves de Mello
BACKGROUND: Totally implantable venous access ports (TIVAPs) are used for prolonged central venous access, allowing the infusion of chemotherapy and other fluids and improving the quality of life of children with cancer. TIVAPs were developed to reduce the infection rates associated with central venous catheters; however, infectious events remain common and have not been fully investigated in pediatric oncology patients. PROCEDURE: A retrospective cohort was formed to investigate risk factors for central line-associated bloodstream infection (CLABSI) in pediatric cancer patients...
September 26, 2016: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/27664891/long-term-central-venous-access-in-a-pediatric-leukemia-population
#17
Aurelia B Fu, Erica I Hodgman, Lorraine S Burkhalter, Rachel Renkes, Tamra Slone, Adam C Alder
BACKGROUND: Central venous access devices (CVADs) play an important role in the management of pediatric oncology patients; unfortunately, they are also associated with potentially serious complication rates. We hypothesized that, despite the significantly different disease courses typical of acute lymphoblastic leukemia and acute myelogenous leukemia, there would be identifiable risk factors for premature CVAD removal. METHODS: We retrospectively studied clinical characteristics and procedure records for all patients admitted with a leukemia diagnosis at our institution from May 2009 to July 2014...
October 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27663229/co-release-of-dicloxacillin-and-thioridazine-from-catheter-material-containing-an-interpenetrating-polymer-network-for-inhibiting-device-associated-staphylococcus-aureus-infection
#18
Michael Stenger, Kasper Klein, Rasmus B Grønnemose, Janne K Klitgaard, Hans J Kolmos, Jes S Lindholt, Martin Alm, Peter Thomsen, Thomas E Andersen
Approximately half of all nosocomial bloodstream infections are caused by bacterial colonization of vascular catheters. Attempts have been made to improve devices using anti-adhesive or antimicrobial coatings; however, it is often difficult to bind coatings stably to catheter materials, and the low amounts of drug in thin-film coatings limit effective long-term release. Interpenetrating polymer networks (IPNs) are polymer hybrid materials with unique drug release properties. While IPNs have been extensively investigated for use in tablet- or capsule-based drug delivery systems, the potential for use of IPNs in drug release medical devices remains largely unexplored...
November 10, 2016: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/27647824/evaluating-safety-of-tunneled-small-bore-central-venous-catheters-in-chronic-kidney-disease-population-a-quality-improvement-initiative
#19
Gauri Bhutani, Mireille El Ters, Walter K Kremers, Joe L Klunder, Sandra J Taler, Amy W Williams, Andrew H Stockland, Marie C Hogan
Introduction Peripherally inserted central venous catheters (PICCs) may adversely impact future successful arteriovenous fistulae (AVF). As part of a quality improvement project, the performance of tunneled small bore tunneled central venous catheters (TSB-CVCs), as alternatives to PICCs, was evaluated. Methods A retrospective observational study, involving individuals ≥18 years of age who underwent TSB-CVC placement by Interventional Radiology at Mayo Clinic, Rochester, MN between 1/1/2010 and 8/30/2013...
September 20, 2016: Hemodialysis International
https://www.readbyqxmd.com/read/27645121/risk-factors-for-persistent-bacteremia-in-infants-with-catheter-related-bloodstream-infection-due-to-coagulase-negative-staphylococcus-in-the-neonatal-intensive-care-unit
#20
Munehiro Furuichi, Isao Miyairi
BACKGROUND: Coagulase-negative Staphylococcus (CoNS) is the predominant cause of catheter-related bloodstream infections (CRBSI). Infants in neonatal intensive care units (NICU) often suffer from CoNS CRBSI, which are often refractory to treatment. OBJECTIVES: We sought to evaluate risk factors for developing persistent bacteremia due to CoNS CRBSI in infants, in order to identify those who require early aggressive management. METHODS: We conducted a retrospective case-control study of infants in the NICU who developed CRBSI due to CoNS...
September 16, 2016: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
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