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https://www.readbyqxmd.com/read/29129459/reliability-and-validity-of-the-youth-leisure-time-sedentary-behavior-questionnaire-ylsbq
#1
Verónica Cabanas-Sánchez, David Martínez-Gómez, Irene Esteban-Cornejo, José Castro-Piñero, Julio Conde-Caveda, Óscar L Veiga
OBJECTIVES: To develop a questionnaire able to assess time spent by youth in a wide range of leisure-time sedentary behaviors (SB) and evaluate its test-retest reliability and criterion validity. DESIGN: Cross-sectional observational. METHODS: The reliability sample included 194 youth, aged 10-18 years, who completed the questionnaire twice, separated by one-week interval. The validity study comprised 1207 participants aged 8-18 years. Participants wore an accelerometer for 7 consecutive days...
November 7, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29030956/spatial-transcriptomes-within-the-pseudomonas-aeruginosa-biofilm-architecture
#2
Yun Heacock-Kang, Zhenxin Sun, Jan Zarzycki-Siek, Ian A McMillan, Michael H Norris, Andrew P Bluhm, Darlene Cabanas, Dawson Fogen, Hung Vo, Stuart P Donachie, Bradley R Borlee, Christopher D Sibley, Shawn Lewenza, Michael J Schurr, Herbert P Schweizer, Tung T Hoang
Bacterial cooperative associations and dynamics in the biofilm microenvironments are of special interest in recent years. Knowledge of localized gene-expression and corresponding bacterial behaviors within the biofilm architecture at a global scale has been limited, due to a lack of robust technology to study limited number of cells in stratified layers of biofilms. With our recent pioneering developments in single bacterial cell transcriptomic analysis technology, we generated herein an unprecedented spatial transcriptome map of the mature in vitro Pseudomonas aeruginosa biofilm model, revealing contemporaneous yet altered bacterial behaviors at different layers within the biofilm architecture (i...
October 14, 2017: Molecular Microbiology
https://www.readbyqxmd.com/read/29023762/tolerance-of-olive-olea-europaea-cv-frantoio-to-verticillium-dahliae-relies-on-both-basal-and-pathogen-induced-differential-transcriptomic-responses
#3
María de la O Leyva-Pérez, Jaime Jiménez-Ruiz, Carmen Gómez-Lama Cabanás, Antonio Valverde-Corredor, Juan B Barroso, Francisco Luque, Jesús Mercado-Blanco
Verticillium wilt of olive (VWO) is one of the most serious biotic constraints for this tree crop. Our knowledge of the genetics of the tolerance/resistance to this disease is very limited. Here we show that tolerance of the cv Frantoio relies on both basal and early pathogen-induced differential transcriptomic responses. A comparative transcriptomic analysis (RNA-seq) was conducted in root tissues of cvs Frantoio (VWO-tolerant) and Picual (VWO-susceptible). RNA samples originated from roots of inoculated olive plants during the early infection stages by Verticillium dahliae (highly virulent, defoliating pathotype)...
October 12, 2017: New Phytologist
https://www.readbyqxmd.com/read/28969467/postpartum-depression-when-should-health-care-providers-identify-those-at-risk
#4
Michelle McKean, Aaron B Caughey, Melanie A Yuracko McKean, Michael D Cabana, Valerie J Flaherman
Maternal postpartum depression (PPD) has an impact on mothers and infants. The American Academy of Pediatrics recommends screening for PPD at well-child visits during the first 6 months. We conducted a secondary data analysis of depression screening data collected each month during months 1 to 12 postpartum for 152 mothers with an infant participating in a randomized controlled trial. We used descriptive statistics to describe the incidence and the cumulative incidence of a positive PPD screen during months 1 to 12 postpartum...
September 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28969456/newborn-skin-findings-in-the-nursery
#5
Nancy Carmona, Michael G Bentz, Manavi M Bhagwat, Michael D Cabana
No abstract text is available yet for this article.
September 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28959922/acceptability-and-feasibility-of-self-sampling-for-the-screening-of-sexually-transmitted-infections-in-cabana-privacy-shelters
#6
Ellen Pittman, Hillary Purcell, Laura Dize, Charlotte Gaydos, Sherine Patterson-Rose, Frank Biro, DeAnna Owens, Lea E Widdice
Screening for sexually transmitted infections (STIs) outside of traditional health-care facilities is limited by the privacy needed for sample collection. We explored the acceptability of privacy shelters for the self-collection of genital swabs and tested the use of privacy shelters during mobile STI screening. Attendees ≥14 years old at two outdoor community events completed a questionnaire that assessed participant characteristics, health-care access, and rating of acceptability of self-collecting penile or vaginal swabs in a privacy shelter and four other private spaces: portable restroom, health van, home, and doctor's office...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28934250/changes-in-striatal-activity-and-functional-connectivity-in-a-mouse-model-of-huntington-s-disease
#7
Magali Cabanas, Fares Bassil, Nicole Mons, Maurice Garret, Yoon H Cho
Hereditary Huntington's disease (HD) is associated with progressive motor, cognitive and psychiatric symptoms. A primary consequence of the HD mutation is the preferential loss of medium spiny projection cells with relative sparing of local interneurons in the striatum. In addition, among GABAergic striatal projection cells, indirect pathway cells expressing D2 dopamine receptors are lost earlier than direct pathway cells expressing D1 receptors. To test in vivo the functional integrity of direct and indirect pathways as well as interneurons in the striatum of male R6/1 transgenic mice, we assessed their c-Fos expression levels induced by a striatal-dependent cognitive task and compared them with age-matched wild-type littermates...
2017: PloS One
https://www.readbyqxmd.com/read/28906252/work-productivity-and-activity-impairment-allergic-specific-wpai-as-questionnaire-using-mobile-technology-the-mask-study
#8
J Bousquet, O VandenPlas, M Bewick, S Arnavielhe, A Bedbrook, R Murray, M van Eerd, J Fonseca, M Morais-Almeida, A Todo Bom, A A Cruz, F Sarquis Serpa, J da Silva, E Menditto, G Passalacqua, C Stellato, M T Ventura, D Caimmi, P Demoly, K C Bergmann, T Keil, L Klimek, R Mösges, S Shamai, T Zuberbier, D Larenas-Linnemann, M Rodriguez Gonzalez, M T Burguete Cabañas, D Ryan, A Sheikh, J M Anto, J Mullol, A Valero, M L Kowalski, P Kuna, B Samolinski, P V Tomazic, S Bosnic-Anticevich, R E O Hehir, G De Vries, D Laune
No abstract text is available yet for this article.
August 29, 2017: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/28906011/the-allergic-rhinitis-and-its-impact-on-asthma-aria-score-of-allergic-rhinitis-using-mobile-technology-correlates-with-quality-of-life-the-mask-study
#9
J Bousquet, S Arnavielhe, A Bedbrook, J Fonseca, M Morais Almeida, A Todo Bom, I Annesi-Maesano, D Caimmi, P Demoly, P Devillier, V Siroux, E Menditto, G Passalacqua, C Stellato, M T Ventura, A A Cruz, F Sarquis Serpa, J da Silva, D Larenas-Linnemann, M Rodriguez Gonzalez, M T Burguete Cabañas, K C Bergmann, T Keil, L Klimek, R Mösges, S Shamai, T Zuberbier, M Bewick, D Price, D Ryan, A Sheikh, J M Anto, J Mullol, A Valero, T Haahtela, E Valovirta, W J Fokkens, P Kuna, B Samolinski, C Bindslev-Jensen, E Eller, S Bosnic-Anticevich, R E O'Hehir, P V Tomazic, A Yorgancioglu, B Gemicioglu, C Bachert, P W Hellings, I Kull, E Melén, M Wickman, M van Eerd, G De Vries
Mobile technology has been used to appraise allergic rhinitis control, but more data are needed. To better assess the importance of mobile technologies in rhinitis control, the ARIA (Allergic Rhinitis and its Impact on Asthma) score ranging from 0 to 4 of the Allergy Diary was compared with EQ-5D (EuroQuol) and WPAI-AS (Work Productivity and Activity Impairment in allergy) in 1288 users in 18 countries. This study showed that quality-of-life data (EQ-5D visual analogue scale and WPA-IS Question 9) are similar in users without rhinitis and in those with mild rhinitis (scores 0-2)...
September 14, 2017: Allergy
https://www.readbyqxmd.com/read/28900146/a-bead-assisted-flow-cytometry-method-for-the-semi-quantitative-analysis-of-extracellular-vesicles
#10
Henar Suárez, Ana Gámez-Valero, Raquel Reyes, Soraya López-Martín, María Josefa Rodríguez, José L Carrascosa, Carlos Cabañas, Francesc E Borràs, María Yáñez-Mó
Most experimental approaches commonly employed for the characterization and quantitation of EVs are time consuming, require of specialized instrumentation and often are rather inaccurate. To circumvent the caveats imposed by EV small size, we used general and specific membrane markers in bead assisted flow cytometry, to provide a semi-quantitative measure of EV content in a given sample. EVs were isolated from in vitro cultured cells-conditioned medium and biological fluids by size exclusion chromatography and coupled to latex beads to allow their detection by standard flow cytometers...
September 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28889863/the-persistence-of-human-dna-in-soil-following-surface-decomposition
#11
Alexandra L Emmons, Jennifer M DeBruyn, Amy Z Mundorff, Kelly L Cobaugh, Graciela S Cabana
Though recent decades have seen a marked increase in research concerning the impact of human decomposition on the grave soil environment, the fate of human DNA in grave soil has been relatively understudied. With the purpose of supplementing the growing body of literature in forensic soil taphonomy, this study assessed the relative persistence of human DNA in soil over the course of decomposition. Endpoint PCR was used to assess the presence or absence of human nuclear and mitochondrial DNA, while qPCR was used to evaluate the quantity of human DNA recovered from the soil beneath four cadavers at the University of Tennessee's Anthropology Research Facility (ARF)...
September 2017: Science & Justice: Journal of the Forensic Science Society
https://www.readbyqxmd.com/read/28860459/association-of-the-plcb1-gene-with-drug-dependence
#12
Judit Cabana-Domínguez, Carlos Roncero, Laura Pineda-Cirera, R Felipe Palma-Álvarez, Elena Ros-Cucurull, Lara Grau-López, Abderaman Esojo, Miquel Casas, Concepció Arenas, Josep Antoni Ramos-Quiroga, Marta Ribasés, Noèlia Fernàndez-Castillo, Bru Cormand
Genetic factors involved in the susceptibility to drug addiction still remain largely unknown. MiRNAs seem to play key roles in the drug-induced plasticity of the brain that likely drives the emergence of addiction. In this work we explored the role of miRNAs in drug addiction. With this aim, we selected 62 SNPs located in the 3'UTR of target genes that are predicted to alter the binding of miRNA molecules and performed a case-control association study in a Spanish sample of 735 cases (mainly cocaine-dependent subjects with multiple drug dependencies) and 739 controls...
August 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28809374/new-horizons-in-anticoagulation-direct-oral-anticoagulants-and-their-implications-in-oral-surgery
#13
V Serrano-Sánchez, J Ripollés-de Ramón, L Collado-Yurrita, I Vaello-Checa, C Colmenero-Ruiz, A Helm, M Ciudad-Cabañas, V Serrano-Cuenca
Thrombotic disorders remain a leading cause of death in the Western World. For decades, vitamin K antagonists used in the prevention of this pathology, such as warfarin or sintrom, were the only oral agents available for long-term anticoagulation, in spite of their disadvantages. Therefore, in recent years, the so-called "new oral anticoagulants" have been introduced in clinical practice to treat those patients whose medical conditions require long-term anticoagulant treatment, replacing traditional oral anticoagulants...
August 15, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28774480/-effect-of-mixed-edaphic-bacterial-inoculants-in-the-early-development-of-improved-cocoa-cultivars-theobroma-cacao-l-in-a-traditional-agroforestry-system-of-oaxaca-mexico
#14
E Hipólito-Romero, M G Carcaño-Montiel, J M Ramos-Prado, E A Vázquez-Cabañas, L López-Reyes, J Ricaño-Rodríguez
Cocoa plant (Theobroma cacao L.) is native from South America and it represents one of the most significant "bio-cultural" resources of Mesoamerica, since it is a region where it was domesticated and had a relevance as ritual drink and as currency in many pre-hispanic cultures until the arrival of the Spaniards who spread its use worldwide, and became it one of the most consumed commodity goods. Through this research, an alternative is proposed to address the problem of cultivars through the introduction of a wide variety of cocoa plants in traditional agroforestry systems, in synergy with the inoculation of nitrogen-fixing and insoluble phosphor solubilizing edaphic bacterial consortia...
July 31, 2017: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/28743416/asymptomatic-choroidal-tubercle-in-a-patient-with-crohn-s-disease-on-adalimumab-treatment
#15
V M Asensio-Sánchez, L Díaz-Cabanas, A Martín-Prieto, B Haro-Álvarez
INTRODUCTION: Adalimumab, an anti-tumour necrosis factor alpha therapy for active Crohn's disease (CD), is associated with increased risks of tuberculosis infection. CASE REPORT: The case is presented of a 48 year-old male with active CD on treatment with adalimumab. After three months, he developed a miliary pulmonary tuberculosis infection, with a solitary non-reactive choroidal tubercle temporal-superior to the optic disc being found in an ophthalmological study...
July 22, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28742507/severe-neurological-abnormalities-in-a-young-boy-with-impaired-thyroid-hormone-sensitivity-due-to-a-novel-mutation-in-the-mct8-gene
#16
Teresa Rego, Carmen Gomez Lado, Paloma Cabanas Rodríguez, Francisco Sousa Santos, Francisco Barros Angueira, Lidia Castro-Feijóo, Jesús Barreiro Conde, Manuel Castro-Gago
Monocarboxylate transporter 8 (MCT8) is an active and specific thyroid hormone transporter into neurons. MCT8 mutations cause an X-linked condition known as Allan-Herndon-Dudley syndrome and are characterized by impaired psychomotor development and typical abnormal thyroid function. We describe a 10-year-old boy with severe cognitive disability, axial hypotonia, spastic quadriplegia and sporadic dyskinetic episodes. He initially presented with thyroid dysfunction (high FT3, low rT3, low FT4 and normal TSH) and generalized retardation of the cerebral and cerebellar myelination in brain magnetic resonance imaging...
April 2017: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28734679/assessment-of-biodistribution-using-mesenchymal-stromal-cells-algorithm-for-study-design-and-challenges-in-detection-methodologies
#17
Blanca Reyes, Maria Isabel Coca, Margarita Codinach, María Dolores López-Lucas, Anna Del Mazo-Barbara, Marta Caminal, Irene Oliver-Vila, Valentín Cabañas, Silvia Lope-Piedrafita, Joan García-López, José M Moraleda, Cesar G Fontecha, Joaquim Vives
BACKGROUND AIMS: Biodistribution of candidate cell-based therapeutics is a critical safety concern that must be addressed in the preclinical development program. We aimed to design a decision tree based on a series of studies included in actual dossiers approved by competent regulatory authorities, noting that the design, execution and interpretation of pharmacokinetics studies using this type of therapy is not straightforward and presents a challenge for both developers and regulators...
July 19, 2017: Cytotherapy
https://www.readbyqxmd.com/read/28689324/fast-detection-of-listeria-monocytogenes-through-a-nanohybrid-quantum-dot-complex
#18
Wendy Donoso, Ricardo I Castro, Luis Guzmán, Zoraya López-Cabaña, Fabiane M Nachtigall, Leonardo S Santos
Listeria monocytogenes is a recognized foodborne pathogen that causes listeriosis in susceptible consumers. Currently, the detection systems for Listeria in food detect live and dead bacteria, being the viable microorganisms most relevant for their ability to cause sickness in the population at risk. For this reason, a new nanohybrid compound was developed for the optical detection of Listeria that was based on polyamidoamine dendrimers functionalized with an auxotrophic cofactor (lipoic acid), together with the coupling of fluorescent semiconductor crystals (quantum dots)...
July 8, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28674111/probiotics-in-the-child-care-center-context-matters
#19
COMMENT
Michael D Cabana, Daniel J Merenstein
No abstract text is available yet for this article.
August 2017: Pediatrics
https://www.readbyqxmd.com/read/28663767/changes-in-physical-activity-and-cardiovascular-mortality-in-older-adults
#20
Sara Higueras-Fresnillo, Pilar Guallar-Castillón, Verónica Cabanas-Sanchez, José R Banegas, Fernando Rodríguez-Artalejo, David Martinez-Gomez
No abstract text is available yet for this article.
April 2017: Journal of Geriatric Cardiology: JGC
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