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https://www.readbyqxmd.com/read/28906252/work-productivity-and-activity-impairment-allergic-specific-wpai-as-questionnaire-using-mobile-technology-the-mask-study
#1
J Bousquet, O VandenPlas, M Bewick, S Arnavielhe, A Bedbrook, R Murray, M van Eerd, J Fonseca, M Morais-Almeida, A Todo Bom, A A Cruz, F Sarquis Serpa, J da Silva, E Menditto, G Passalacqua, C Stellato, M T Ventura, D Caimmi, P Demoly, K C Bergmann, T Keil, L Klimek, R Mösges, S Shamai, T Zuberbier, D Larenas-Linnemann, M Rodriguez Gonzalez, M T Burguete Cabañas, D Ryan, A Sheikh, J M Anto, J Mullol, A Valero, M L Kowalski, P Kuna, B Samolinski, P V Tomazic, S Bosnic-Anticevich, R E O Hehir, G De Vries, D Laune
No abstract text is available yet for this article.
August 29, 2017: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/28906011/the-aria-score-of-allergic-rhinitis-using-mobile-technology-correlates-with-quality-of-life-the-mask-study
#2
J Bousquet, S Arnavielhe, A Bedbrook, J Fonseca, M Morais Almeida, A Todo Bom, I Annesi-Maesano, D Caimmi, P Demoly, P Devillier, V Siroux, E Menditto, G Passalacqua, C Stellato, M T Ventura, A A Cruz, F S Serpa, J da Silva, D Larenas-Linnemann, M Rodriguez Gonzalez, M T Burguete Cabañas, K C Bergmann, T Keil, L Klimek, R Mösges, S Shamai, T Zuberbier, M Bewick, D Price, D Ryan, A Sheikh, J M Anto, J Mullol, A Valero, T Haahtela, E Valovirta, W J Fokkens, P Kuna, B Samolinski, C Bindslev-Jensen, E Eller, S Bosnic-Anticevich, R E O'Hehir, P V Tomazic, A Yorgancioglu, B Gemicioglu, C Bachert, P W Hellings, I Kull, E Melén, M Wickman, M van Eerd, G De Vries
Mobile technology has been used to appraise allergic rhinitis control but more data are needed. In order to better assess the importance of mobile technologies in rhinitis control, the ARIA (Allergic Rhinitis and its Impact on Asthma) score ranging from 0 to 4 of the Allergy Diary was compared with EQ-5D (EuroQuol) and WPAI-AS (Work Productivity and Activity Impairment in allergy) in 1,288 users in 18 countries. This study showed that quality-of-life data (EQ-5D visual analogue scale and WPA-IS Question 9) are similar in users without rhinitis and in those with mild rhinitis (scores 0-2)...
September 14, 2017: Allergy
https://www.readbyqxmd.com/read/28900146/a-bead-assisted-flow-cytometry-method-for-the-semi-quantitative-analysis-of-extracellular-vesicles
#3
Henar Suárez, Ana Gámez-Valero, Raquel Reyes, Soraya López-Martín, María Josefa Rodríguez, José L Carrascosa, Carlos Cabañas, Francesc E Borràs, María Yáñez-Mó
Most experimental approaches commonly employed for the characterization and quantitation of EVs are time consuming, require of specialized instrumentation and often are rather inaccurate. To circumvent the caveats imposed by EV small size, we used general and specific membrane markers in bead assisted flow cytometry, to provide a semi-quantitative measure of EV content in a given sample. EVs were isolated from in vitro cultured cells-conditioned medium and biological fluids by size exclusion chromatography and coupled to latex beads to allow their detection by standard flow cytometers...
September 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28889863/the-persistence-of-human-dna-in-soil-following-surface-decomposition
#4
Alexandra L Emmons, Jennifer M DeBruyn, Amy Z Mundorff, Kelly L Cobaugh, Graciela S Cabana
Though recent decades have seen a marked increase in research concerning the impact of human decomposition on the grave soil environment, the fate of human DNA in grave soil has been relatively understudied. With the purpose of supplementing the growing body of literature in forensic soil taphonomy, this study assessed the relative persistence of human DNA in soil over the course of decomposition. Endpoint PCR was used to assess the presence or absence of human nuclear and mitochondrial DNA, while qPCR was used to evaluate the quantity of human DNA recovered from the soil beneath four cadavers at the University of Tennessee's Anthropology Research Facility (ARF)...
September 2017: Science & Justice: Journal of the Forensic Science Society
https://www.readbyqxmd.com/read/28860459/association-of-the-plcb1-gene-with-drug-dependence
#5
Judit Cabana-Domínguez, Carlos Roncero, Laura Pineda-Cirera, R Felipe Palma-Álvarez, Elena Ros-Cucurull, Lara Grau-López, Abderaman Esojo, Miquel Casas, Concepció Arenas, Josep Antoni Ramos-Quiroga, Marta Ribasés, Noèlia Fernàndez-Castillo, Bru Cormand
Genetic factors involved in the susceptibility to drug addiction still remain largely unknown. MiRNAs seem to play key roles in the drug-induced plasticity of the brain that likely drives the emergence of addiction. In this work we explored the role of miRNAs in drug addiction. With this aim, we selected 62 SNPs located in the 3'UTR of target genes that are predicted to alter the binding of miRNA molecules and performed a case-control association study in a Spanish sample of 735 cases (mainly cocaine-dependent subjects with multiple drug dependencies) and 739 controls...
August 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28809374/new-horizons-in-anticoagulation-direct-oral-anticoagulants-and-their-implications-in-oral-surgery
#6
V Serrano-Sánchez, J Ripollés-de Ramón, L Collado-Yurrita, I Vaello-Checa, C Colmenero-Ruiz, A Helm, M Ciudad-Cabañas, V Serrano-Cuenca
Thrombotic disorders remain a leading cause of death in the Western World. For decades, vitamin K antagonists used in the prevention of this pathology, such as warfarin or sintrom, were the only oral agents available for long-term anticoagulation, in spite of their disadvantages. Therefore, in recent years, the so-called "new oral anticoagulants" have been introduced in clinical practice to treat those patients whose medical conditions require long-term anticoagulant treatment, replacing traditional oral anticoagulants...
August 15, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28774480/-effect-of-mixed-edaphic-bacterial-inoculants-in-the-early-development-of-improved-cocoa-cultivars-theobroma-cacao-l-in-a-traditional-agroforestry-system-of-oaxaca-mexico
#7
E Hipólito-Romero, M G Carcaño-Montiel, J M Ramos-Prado, E A Vázquez-Cabañas, L López-Reyes, J Ricaño-Rodríguez
Cocoa plant (Theobroma cacao L.) is native from South America and it represents one of the most significant "bio-cultural" resources of Mesoamerica, since it is a region where it was domesticated and had a relevance as ritual drink and as currency in many pre-hispanic cultures until the arrival of the Spaniards who spread its use worldwide, and became it one of the most consumed commodity goods. Through this research, an alternative is proposed to address the problem of cultivars through the introduction of a wide variety of cocoa plants in traditional agroforestry systems, in synergy with the inoculation of nitrogen-fixing and insoluble phosphor solubilizing edaphic bacterial consortia...
July 31, 2017: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/28743416/asymptomatic-choroidal-tubercle-in-a-patient-with-crohn-s-disease-on-adalimumab-treatment
#8
V M Asensio-Sánchez, L Díaz-Cabanas, A Martín-Prieto, B Haro-Álvarez
INTRODUCTION: Adalimumab, an anti-tumour necrosis factor alpha therapy for active Crohn's disease (CD), is associated with increased risks of tuberculosis infection. CASE REPORT: The case is presented of a 48 year-old male with active CD on treatment with adalimumab. After three months, he developed a miliary pulmonary tuberculosis infection, with a solitary non-reactive choroidal tubercle temporal-superior to the optic disc being found in an ophthalmological study...
July 22, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28742507/severe-neurological-abnormalities-in-a-young-boy-with-impaired-thyroid-hormone-sensitivity-due-to-a-novel-mutation-in-the-mct8-gene
#9
Teresa Rego, Carmen Gomez Lado, Paloma Cabanas Rodríguez, Francisco Sousa Santos, Francisco Barros Angueira, Lidia Castro-Feijóo, Jesús Barreiro Conde, Manuel Castro-Gago
Monocarboxylate transporter 8 (MCT8) is an active and specific thyroid hormone transporter into neurons. MCT8 mutations cause an X-linked condition known as Allan-Herndon-Dudley syndrome and are characterized by impaired psychomotor development and typical abnormal thyroid function. We describe a 10-year-old boy with severe cognitive disability, axial hypotonia, spastic quadriplegia and sporadic dyskinetic episodes. He initially presented with thyroid dysfunction (high FT3, low rT3, low FT4 and normal TSH) and generalized retardation of the cerebral and cerebellar myelination in brain magnetic resonance imaging...
April 2017: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28734679/assessment-of-biodistribution-using-mesenchymal-stromal-cells-algorithm-for-study-design-and-challenges-in-detection-methodologies
#10
Blanca Reyes, Maria Isabel Coca, Margarita Codinach, María Dolores López-Lucas, Anna Del Mazo-Barbara, Marta Caminal, Irene Oliver-Vila, Valentín Cabañas, Silvia Lope-Piedrafita, Joan García-López, José M Moraleda, Cesar G Fontecha, Joaquim Vives
BACKGROUND AIMS: Biodistribution of candidate cell-based therapeutics is a critical safety concern that must be addressed in the preclinical development program. We aimed to design a decision tree based on a series of studies included in actual dossiers approved by competent regulatory authorities, noting that the design, execution and interpretation of pharmacokinetics studies using this type of therapy is not straightforward and presents a challenge for both developers and regulators...
July 19, 2017: Cytotherapy
https://www.readbyqxmd.com/read/28689324/fast-detection-of-listeria-monocytogenes-through-a-nanohybrid-quantum-dot-complex
#11
Wendy Donoso, Ricardo I Castro, Luis Guzmán, Zoraya López-Cabaña, Fabiane M Nachtigall, Leonardo S Santos
Listeria monocytogenes is a recognized foodborne pathogen that causes listeriosis in susceptible consumers. Currently, the detection systems for Listeria in food detect live and dead bacteria, being the viable microorganisms most relevant for their ability to cause sickness in the population at risk. For this reason, a new nanohybrid compound was developed for the optical detection of Listeria that was based on polyamidoamine dendrimers functionalized with an auxotrophic cofactor (lipoic acid), together with the coupling of fluorescent semiconductor crystals (quantum dots)...
July 8, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28674111/probiotics-in-the-child-care-center-context-matters
#12
Michael D Cabana, Daniel J Merenstein
No abstract text is available yet for this article.
August 2017: Pediatrics
https://www.readbyqxmd.com/read/28663767/changes-in-physical-activity-and-cardiovascular-mortality-in-older-adults
#13
Sara Higueras-Fresnillo, Pilar Guallar-Castillón, Verónica Cabanas-Sanchez, José R Banegas, Fernando Rodríguez-Artalejo, David Martinez-Gomez
No abstract text is available yet for this article.
April 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28648366/-oxidative-stress-in-perinatal-asphyxia-and-hypoxic-ischaemic-encephalopathy
#14
Antonio Nuñez, Isabel Benavente, Dorotea Blanco, Héctor Boix, Fernando Cabañas, Mercedes Chaffanel, Belén Fernández-Colomer, José Ramón Fernández-Lorenzo, Begoña Loureiro, María Teresa Moral, Antonio Pavón, Inés Tofé, Eva Valverde, Máximo Vento
Birth asphyxia is one of the principal causes of early neonatal death. In survivors it may evolve to hypoxic-ischaemic encephalopathy and major long-term neurological morbidity. Prolonged and intense asphyxia will lead to energy exhaustion in tissues exclusively dependent on aerobic metabolism, such as the central nervous system. Energy deficit leads to ATP-dependent pumps blockage, with the subsequent loss of neuronal transmembrane potential. The most sensitive areas of the brain will die due to necrosis. In more resistant areas, neuronal hyper-excitability, massive entrance of ionic calcium, activation of NO-synthase, free radical generation, and alteration in mitochondrial metabolism will lead to a secondary energy failure and programmed neuronal death by means of the activation of the caspase pathways...
June 22, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28643460/periodic-limb-movement-in-sleep-and-sickle-cell-disease-a-neglected-association
#15
Ana C Cabañas-Pedro, Suely Roizenblatt, Altay A L de Souza, Sérgio Tufik, Maria S Figueiredo
High frequency of periodic limb movements in sleep (PLMS) has been described among children with sickle cell disease (SCD), but there is little information about PLMS among adults with SCD. We aim to determine the frequency of PLMS among adults with SCD and to identify possible associations with iron status and haemolytic parameters. We analysed polysomnography on 99 adults: 74 with sickle cell anaemia (HbSS), 19 with HbSC (double heterozygosis HbS and HbC) and 6 with HbS-beta thalassaemia. Laboratory data were collected close to the time of the polysomnography examination...
June 23, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28636826/degradation-mechanisms-of-magnesium-metal-anodes-in-electrolytes-based-on-cf3so2-2n-at-high-current-densities
#16
Hyun Deog Yoo, Sang-Don Han, Igor L Bolotin, Gene M Nolis, Ryan D Bayliss, Anthony K Burrell, John T Vaughey, Jordi Cabana
The energy density of rechargeable batteries utilizing metals as anodes surpasses that of Li ion batteries, which employ carbon instead. Among possible metals, magnesium represents a potential alternative to the conventional choice, lithium, in terms of storage density, safety, stability, and cost. However, a major obstacle for metal-based batteries is the identification of electrolytes that show reversible deposition/dissolution of the metal anode and support reversible intercalation of ions into a cathode...
July 5, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28635047/feeding-asian-pangolins-an-assessment-of-current-diets-fed-in-institutions-worldwide
#17
Francis Cabana, Amy Plowman, Thai Van Nguyen, Shih-Chien Chin, Sung-Lin Wu, Hsuan-Yi Lo, Hirofumi Watabe, Fujio Yamamoto
Pangolins are ant specialists which are under intense threat from the illegal wildlife trade. Nutrition has notoriously been their downfall in captivity and is still an issue in regards to rescue and rehabilitation. We analyzed the nutrient content of diets used by institutions that are successfully keeping Asian pangolins and to assess the variety of the ingredients and nutrients, compared these with the nutritional requirements of potential nutritional model species. We performed intake studies at five institutions and also had data from three other institutions...
June 20, 2017: Zoo Biology
https://www.readbyqxmd.com/read/28624938/synergetic-integration-of-laccase-and-versatile-peroxidase-with-magnetic-silica-microspheres-towards-remediation-of-biorefinery-wastewater
#18
Dhanya Vishnu, Gerard Neeraj, Ramachandran Swaroopini, Ravi Shobana, Vaidyanathan Vinoth Kumar, Hubert Cabana
In this study, a tailor-made biocatalyst consisting of a co-immobilized lignolytic enzyme cascade on multi-functionalized magnetic silica microspheres (MSMS) was developed. Physical adsorption was the most promising strategy for the synthesis of individual immobilized laccase (IL), immobilized versatile peroxidase (IP), as well as co-immobilized laccase (Lac) and versatile peroxidase (VP) with an enzyme activity recovery of about 79, 93, 27, and 27.5%, respectively. Similarly, the biocatalytic load of 116, 183, 23...
June 17, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28559037/repeated-emergency-medical-services-use-by-older-adults-analysis-of-a-comprehensive-statewide-database
#19
Christopher S Evans, Timothy F Platts-Mills, Antonio R Fernandez, Joseph M Grover, Jose G Cabanas, Mehul D Patel, Gary M Vilke, Jane H Brice
STUDY OBJECTIVE: The objective of this study is to characterize repeated emergency medical services (EMS) transports among older adults across a large and socioeconomically diverse region. METHODS: Using the North Carolina Prehospital Medical Information System, we analyzed the frequency of repeated EMS transports within 30 days of an index EMS transport among adults aged 65 years and older from 2010 to 2015. We used multivariable logistic regressions to determine characteristics associated with repeated EMS transport...
May 27, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28557773/corticosteroids-and-asthma-too-much-or-too-little
#20
Michael D Cabana
No abstract text is available yet for this article.
May 2017: Pediatrics
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