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https://www.readbyqxmd.com/read/28643460/periodic-limb-movement-in-sleep-and-sickle-cell-disease-a-neglected-association
#1
Ana C Cabañas-Pedro, Suely Roizenblatt, Altay A L de Souza, Sérgio Tufik, Maria S Figueiredo
High frequency of periodic limb movements in sleep (PLMS) has been described among children with sickle cell disease (SCD), but there is little information about PLMS among adults with SCD. We aim to determine the frequency of PLMS among adults with SCD and to identify possible associations with iron status and haemolytic parameters. We analysed polysomnography on 99 adults: 74 with sickle cell anaemia (HbSS), 19 with HbSC (double heterozygosis HbS and HbC) and 6 with HbS-beta thalassaemia. Laboratory data were collected close to the time of the polysomnography examination...
June 23, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28636826/degradation-mechanisms-of-magnesium-metal-anodes-in-electrolytes-based-on-cf3so2-2n-at-high-current-densities
#2
Hyun Deog Yoo, Sang-Don Han, Igor L Bolotin, Gene M Nolis, Ryan D Bayliss, Anthony K Burrell, John T Vaughey, Jordi Cabana
The energy density of rechargeable batteries utilizing metals as anodes surpasses Li-ion batteries, which employ carbon instead. Among possible metals, magnesium represents a potential alternative to the conventional choice, lithium, in terms of storage density, safety, stability, and cost. However, a major obstacle for metal-based batteries is the identification of electrolytes that show reversible deposition/dissolution of the metal anode and support reversible intercalation of ions into a cathode. Traditional Grignard-based Mg electrolytes are excellent toward reversible deposition of Mg, but their limited anodic stability and compatibility with oxide cathodes hinder their applicability in Mg batteries with higher voltage...
June 21, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28624938/synergetic-integration-of-laccase-and-versatile-peroxidase-with-magnetic-silica-microspheres-towards-remediation-of-biorefinery-wastewater
#3
Dhanya Vishnu, Gerard Neeraj, Ramachandran Swaroopini, Ravi Shobana, Vaidyanathan Vinoth Kumar, Hubert Cabana
In this study, a tailor-made biocatalyst consisting of a co-immobilized lignolytic enzyme cascade on multi-functionalized magnetic silica microspheres (MSMS) was developed. Physical adsorption was the most promising strategy for the synthesis of individual immobilized laccase (IL), immobilized versatile peroxidase (IP), as well as co-immobilized laccase (Lac) and versatile peroxidase (VP) with an enzyme activity recovery of about 79, 93, 27, and 27.5%, respectively. Similarly, the biocatalytic load of 116, 183, 23...
June 17, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28559037/repeated-emergency-medical-services-use-by-older-adults-analysis-of-a-comprehensive-statewide-database
#4
Christopher S Evans, Timothy F Platts-Mills, Antonio R Fernandez, Joseph M Grover, Jose G Cabanas, Mehul D Patel, Gary M Vilke, Jane H Brice
STUDY OBJECTIVE: The objective of this study is to characterize repeated emergency medical services (EMS) transports among older adults across a large and socioeconomically diverse region. METHODS: Using the North Carolina Prehospital Medical Information System, we analyzed the frequency of repeated EMS transports within 30 days of an index EMS transport among adults aged 65 years and older from 2010 to 2015. We used multivariable logistic regressions to determine characteristics associated with repeated EMS transport...
May 27, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28557773/corticosteroids-and-asthma-too-much-or-too-little
#5
Michael D Cabana
No abstract text is available yet for this article.
May 2017: Pediatrics
https://www.readbyqxmd.com/read/28553726/randomized-controlled-trial-of-a-clinic-based-intervention-to-promote-healthy-beverage-consumption-among-latino-children
#6
Amy L Beck, Alicia Fernandez, Jenssy Rojina, Michael Cabana
The objective of this study was to evaluate an educational module for Latino parents about the health effects of sweet beverages. Latino parents were randomized to receive the beverage module or a control module. Child beverage consumption was assessed at baseline, 2 weeks, 2 months, and 3 months via a beverage recall survey. At 2-week follow-up, children of intervention participants had a mean reduction in 7-day total sugar-sweetened beverage and 100% fruit juice consumption of 16 ounces while controls had a mean increase of 4 ounces ( P = ...
May 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28548836/intergranular-cracking-as-a-major-cause-of-long-term-capacity-fading-of-layered-cathodes
#7
Hao Liu, Mark Wolf, Khim Karki, Young-Sang Yu, Eric A Stach, Jordi Cabana, Karena W Chapman, Peter J Chupas
Capacity fading has limited commercial layered Li-ion battery electrodes to <70% of their theoretical capacity. Higher capacities can be achieved initially by charging to higher voltages, however, these gains are eroded by a faster fade in capacity. Increasing lifetimes and reversible capacity are contingent on identifying the origin of this capacity fade to inform electrode design and synthesis. We used operando X-ray diffraction to observe how the lithiation-delithiation reactions within a LiNi0.8Co0.15Al0...
June 14, 2017: Nano Letters
https://www.readbyqxmd.com/read/28521822/central-nervous-system-manganese-induced-lesions-and-clinical-consequences-in-patients-with-hereditary-hemorrhagic-telangiectasia
#8
M M Serra, C H Besada, A Cabana Cal, A Saenz, C V Stefani, D Bauso, A B Golimstok, J C Bandi, D H Giunta, C M Elizondo
BACKGROUND: Around 47-74% of patients with hereditary hemorrhagic telangiectasia (HHT) have hepatic vascular malformations (HVMs); magnetic resonance images (MRI) of the central nervous system (CNS) might show in T1 sequences a hyper-intensity signal in different areas, mainly in the basal ganglia (BG) as consequence of manganese (Mn) deposits as observed in cirrhotic patients. These patients might suffer from different neuropsychiatric disorders (hepatic encephalopathy). In HHT patients, even in the presence of hepatic shunts, hepatocellular function is usually preserved...
May 18, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28521558/rising-utilization-of-inpatient-pediatric-asthma-pathways
#9
Sunitha V Kaiser, Jonathan Rodean, Arpi Bekmezian, Matt Hall, Samir S Shah, Sanjay Mahant, Kavita Parikh, Rustin Morse, Henry Puls, Michael D Cabana
INTRODUCTION: Clinical pathways are detailed care plans that operationalize evidence-based guidelines into an accessible format for health providers. Their goal is to link evidence to practice to optimize patient outcomes and delivery efficiency. It is unknown to what extent inpatient pediatric asthma pathways are being utilized nationally. OBJECTIVES: (1) Describe inpatient pediatric asthma pathway design and implementation across a large hospital network. (2) Compare characteristics of hospitals with and without pathways...
May 19, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28521324/the-role-of-hydrolyzed-formula-in-allergy-prevention
#10
Michael D Cabana
Asthma, eczema, food allergy, and allergic rhinitis are some of the most common pediatric, chronic conditions in the world. Breastfeeding is the optimal way to feed all infants. For those infants who are exposed to infant formula, some studies suggest that certain partially hydrolyzed or extensively hydrolyzed formulas may decrease the risk of allergic disease compared to nonhydrolyzed formulas for children with a family history of atopic disease. Overall, there is some evidence to suggest that partially hydrolyzed whey formulas and extensively hydrolyzed casein formulas may decrease the risk of developing eczema for infants at high risk of allergic disease...
2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28503997/television-during-meals-in-the-first-4-years-of-life
#11
RANDOMIZED CONTROLLED TRIAL
Lindsay M Thimmig, Michael D Cabana, Michael G Bentz, Katherine Potocka, Amy Beck, Lawrence Fong, Cewin Chao, Aaron B Caughey, Angela Wong, Michelle McKean
The development of children's mealtime television (TV) habits has not been well studied. We assessed whether mealtime TV habits established in infancy will persist into early childhood. We analyzed data collected through parent surveys at birth and at 6-month intervals from a randomized controlled trial. We used t-tests, χ(2) tests, and a multivariable logistic regression to determine if family characteristics were associated with mealtime TV. A McNemar test was used to assess whether mealtime TV exposure changed over time...
June 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28499155/simple-screening-protocol-for-identification-of-potential-mycoremediation-tools-for-the-elimination-of-polycyclic-aromatic-hydrocarbons-and-phenols-from-hyperalkalophile-industrial-effluents
#12
Ramón Alberto Batista-García, Vaidyanathan Vinoth Kumar, Arielle Ariste, Omar Eduardo Tovar-Herrera, Olivier Savary, Heidy Peidro-Guzmán, Deborah González-Abradelo, Stephen A Jackson, Alan D W Dobson, María Del Rayo Sánchez-Carbente, Jorge Luis Folch-Mallol, Roland Leduc, Hubert Cabana
A number of fungal strains belonging to the ascomycota, basidiomycota and zygomycota genera were subjected to an in vitro screening regime to assess their ligninolytic activity potential, with a view to their potential use in mycoremediation-based strategies to remove phenolic compounds and polycyclic aromatic hydrocarbons (PAHs) from industrial wastewaters. All six basidiomycetes completely decolorized remazol brilliant blue R (RBBR), while also testing positive in both the guaiacol and gallic acid tests indicating good levels of lignolytic activity...
May 9, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28444791/trialling-nutrient-recommendations-for-slow-lorises-nycticebus-spp-based-on-wild-feeding-ecology
#13
F Cabana, E Dierenfeld, W Wirdateti, G Donati, K A I Nekaris
Slow loris (Nycticebus spp.) captive diets have been based on routine and anecdotes rather than scientific fact. The growing body of evidence contradicts the high fruit diet supported by such anecdotes. Non-human primate nutrient requirements are grouped into new (based on the common marmoset Callithrix jacchus) or old world (based on rhesus macaques Macaca mulatta) primates. Slow lorises are known to suffer from many health ailments in captivity such as dental disease, obesity, wasting and kidney issues all of which have been linked to diet...
April 26, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28406071/validation-and-reliability-of-the-spanish-version-of-the-function-in-sitting-test-s-fist-to-assess-sitting-balance-in-subacute-post-stroke-adult-patients
#14
Rosa Cabanas-Valdés, Caritat Bagur-Calafat, Fernanda Maria Caballero-Gómez, Carmen Cervera-Cuenca, Raúl Moya-Valdés, Pere Ramón Rodríguez-Rubio, Gerard Urrútia
BACKGROUND: Function in Sitting Test (FIST) is a clinical functional assessment of sitting balance validated in adults with stroke. For a major use of this, the test is recommended to be translated in Spanish-speaking countries. OBJECTIVES: Translate to Spanish the FIST and determine its intra-rater and inter-rater reliabilities and concurrent validity as a measure of sitting balance in adult individuals with stroke. METHODS: The original version was translated into Spanish and was agreed by a team of experts...
April 13, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/28402365/vectorization-of-ultrasound-responsive-nanoparticles-in-placental-mesenchymal-stem-cells-for-cancer-therapy
#15
Juan L Paris, Paz de la Torre, M Victoria Cabañas, Miguel Manzano, Montserrat Grau, Ana I Flores, María Vallet-Regí
A new platform constituted by engineered responsive nanoparticles transported by human mesenchymal stem cells is here presented as a proof of concept. Ultrasound-responsive mesoporous silica nanoparticles are coated with polyethylenimine to favor their effective uptake by decidua-derived mesenchymal stem cells. The responsive-release ability of the designed nanoparticles is confirmed, both in vial and in vivo. In addition, this capability is maintained inside the cells used as carriers. The migration capacity of the nanoparticle-cell platform towards mammary tumors is assessed in vitro...
May 4, 2017: Nanoscale
https://www.readbyqxmd.com/read/28381192/downregulation-of-sorting-nexin-10-is-associated-with-overexpression-of-mir-30d-during-liver-cancer-progression-in-rats
#16
Nancy Cervantes-Anaya, Alberto Ponciano-Gómez, Guadalupe Soledad López-Álvarez, Christian Gonzalez-Reyes, Sergio Hernández-Garcia, María Asunción Cabañas-Cortes, José Efraín Garrido-Guerrero, Saúl Villa-Treviño
As of 2012, liver cancer was the second leading cause of death worldwide, and hepatocellular carcinoma is the most common primary cancer of the liver. The identification of molecules that might be molecular markers or therapeutic targets is urgently needed to improve clinical management. Based on a microarray analysis performed in our laboratory, we selected six genes-namely, ANXA2, DYNLT1, PFKP, PLA2G7, KRT19, and SNX10-as candidates for validation as tumor markers of liver cancer in a rat model. Their patterns of overexpression in preneoplastic lesions and established tumors at 10 different time points between 24 h and 18 months were analyzed to identify putative tumor markers for further studies...
April 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28351168/long-term-follow-up-of-a-randomized-controlled-trial-on-additional-core-stability-exercises-training-for-improving-dynamic-sitting-balance-and-trunk-control-in-stroke-patients
#17
Rosa Cabanas-Valdés, Caritat Bagur-Calafat, Montserrat Girabent-Farrés, Fernanda Mª Caballero-Gómez, Helena du Port de Pontcharra-Serra, Ana German-Romero, Gerard Urrútia
OBJECTIVE: Analyse the effect of core stability exercises in addition to conventional physiotherapy training three months after the intervention ended. DESIGN: A randomized controlled trial. SETTING: Outpatient services. SUBJECTS: Seventy-nine stroke survivors. INTERVENTIONS: In the intervention period, both groups underwent conventional physiotherapy performed five days/week for five weeks, and in addition the experimental group performed core stability exercises for 15 minutes/day...
March 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28347550/unexpected-obstetric-haemorrhage-krukenberg-tumour
#18
J Montoro García, M Cabellos Olivares, A Cabana Navia, J López Saña, J R Rodríguez Fraile
Obstetric haemorrhage can endanger the lives of mother and foetus. It often occurs unexpectedly without clear predictors. A high degree of suspicion helps to avoid delaying resuscitation measures. We present the case of a ruptured ovarian metastasis that occurred during labour. It caused a massive bleed forcing a caesarean section due to non-reassuring foetal status. This was an unprecedented and undescribed onset of Krukenberg tumour formation. Malignant tumours in pregnancy are rare and difficult to diagnose due to their clinical manifestations which often overlap with those of pregnancy itself (dyspepsia, nausea and bloating)...
March 24, 2017: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/28336532/moag-4-promotes-the-aggregation-of-%C3%AE-synuclein-by-competing-with-self-protective-electrostatic-interactions
#19
Yuichi Yoshimura, Mats A Holmberg, Predrag Kukic, Camilla B Andersen, Alejandro Mata-Cabana, S Fabio Falsone, Michele Vendruscolo, Ellen A A Nollen, Frans A A Mulder
Aberrant protein aggregation underlies a variety of age-related neurodegenerative disorders, including Alzheimer's and Parkinson's diseases. Little is known, however, about the molecular mechanisms that modulate the aggregation process in the cellular environment. Recently, MOAG-4/SERF has been identified as a class of evolutionarily conserved proteins that positively regulates aggregate formation. Here, by using nuclear magnetic resonance (NMR) spectroscopy, we examine the mechanism of action of MOAG-4 by characterizing its interaction with α-synuclein (α-Syn)...
May 19, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28306505/identification-of-an-rna-polymerase-iii-regulator-linked-to-disease-associated-protein-aggregation
#20
Olga Sin, Tristan de Jong, Alejandro Mata-Cabana, Michelle Kudron, Mohamad Amr Zaini, Francesco A Aprile, Renée I Seinstra, Esther Stroo, Roméo Willinge Prins, Céline N Martineau, Hai Hui Wang, Wytse Hogewerf, Anne Steinhof, Erich E Wanker, Michele Vendruscolo, Cornelis F Calkhoven, Valerie Reinke, Victor Guryev, Ellen A A Nollen
Protein aggregation is associated with age-related neurodegenerative disorders, such as Alzheimer's and polyglutamine diseases. As a causal relationship between protein aggregation and neurodegeneration remains elusive, understanding the cellular mechanisms regulating protein aggregation will help develop future treatments. To identify such mechanisms, we conducted a forward genetic screen in a C. elegans model of polyglutamine aggregation and identified the protein MOAG-2/LIR-3 as a driver of protein aggregation...
March 16, 2017: Molecular Cell
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