Masanori Tsubosaka, Masahiro Maruyama, Elaine Lui, Junichi Kushioka, Masakazu Toya, Qi Gao, Huaishuang Shen, Xueping Li, Simon Kwoon-Ho Chow, Ning Zhang, Yunzhi Peter Yang, Stuart B Goodman
Nontraumatic osteonecrosis of the femoral head (ONFH) is a refractory condition that commonly results in femoral head collapse and degenerative arthritis of the hip. In the early stages, surgical procedures for hip preservation, including core decompression (CD), have been developed to prevent progressive collapse of the femoral head. Optimization of bone regeneration and biological augmentation may further enhance the therapeutic efficacy of CD for ONFH. Thus, combining CD with cell-based therapy has recently been proposed...
January 2024: Journal of Biomedical Materials Research. Part B, Applied Biomaterials