keyword
MENU ▼
Read by QxMD icon Read
search

proprioceptor

keyword
https://www.readbyqxmd.com/read/27880894/requirement-for-dicer-in-maintenance-of-monosynaptic-sensory-motor-circuits-in-the-spinal-cord
#1
Fumiyasu Imai, Xiaoting Chen, Matthew T Weirauch, Yutaka Yoshida
In contrast to our knowledge of mechanisms governing circuit formation, our understanding of how neural circuits are maintained is limited. Here, we show that Dicer, an RNaseIII protein required for processing microRNAs (miRNAs), is essential for maintenance of the spinal monosynaptic stretch reflex circuit in which group Ia proprioceptive sensory neurons form direct connections with motor neurons. In postnatal mice lacking Dicer in proprioceptor sensory neurons, there are no obvious defects in specificity or formation of monosynaptic sensory-motor connections...
November 22, 2016: Cell Reports
https://www.readbyqxmd.com/read/27868313/nutrient-dependent-increased-dendritic-arborization-of-somatosensory-neurons
#2
Kaori Watanabe, Yuki Furumizo, Tadao Usui, Yukako Hattori, Tadashi Uemura
Suboptimal nutrition imposes developmental constraints on infant animals, which marshal adaptive responses to eventually become mature adults. Such responses are mounted at multiple levels from systemic to cellular. At the cellular level, the underlying mechanisms of cell proliferation control have been intensively studied. However, less is known about how growth of postmitotic and morphologically complex cells, such as neurons, is controlled by nutritional status. We address this question using Class I and Class IV dendritic arborization neurons in Drosophila larvae...
November 21, 2016: Genes to Cells: Devoted to Molecular & Cellular Mechanisms
https://www.readbyqxmd.com/read/27669454/a-comparative-animal-study-of-tendon-grafts-healing-after-remnant-preserving-versus-conventional-anterior-cruciate-ligament-reconstruction
#3
Lei Zhang, Kan Jiang, Hao Chai, Mei Zhou, Jingping Bai
BACKGROUND The aim of this study was to determine if anterior cruciate ligament (ACL) reconstruction by remnant preservation promotes cell proliferation, vascularization, proprioception recovery, and improved biomechanical properties of the tendon grafts. MATERIAL AND METHODS 75 New Zealand rabbits were randomly assigned into the control group (group A), conventional ACL reconstruction group (group B), ACL reconstruction using remnant preservation and graft through remnant sleeve technique group (group C), and ACL reconstruction using remnant preservation and remnant tensioning technique group (group D)...
September 26, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27665954/an-evaluation-of-the-posterior-cruciate-ligament-function-in-total-knee-arthroplasty-with-regard-to-its-morphology-and-clinical-properties
#4
Dariusz Marczak, Jacek Kowalczewski, Tomasz Okoń, Marek Synder, Marcin Piotr Sibiński
The aim of the study was to determine the degree of PCL (posterior cruciate ligament) degeneration and the reduction in the number of its mechanoreceptors, in patients with advanced degenerative joint disease. PCLs taken from study group of 50 patients in the mean age of 70.7 (53 to 84 years) with a diagnosis of advanced idiopathic osteoarthritis undergoing condylar TKA were compared to those taken form the control group of 10 knee joints of cadavers. Groups were matched with regard to sex and age. Histological examination of PCLs of the study group showed changes of an inflammatory process and no significant signs of osteoarthritis in the control group...
September 26, 2016: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/27486390/whisking-kinematics-enables-object-localization-in-head-centered-coordinates-based-on-tactile-information-from-a-single-vibrissa
#5
Anne E T Yang, Mitra J Z Hartmann
During active tactile exploration with their whiskers (vibrissae), rodents can rapidly orient to an object even though there are very few proprioceptors in the whisker muscles. Thus a long-standing question in the study of the vibrissal system is how the rat can localize an object in head-centered coordinates without muscle-based proprioception. We used a three-dimensional model of whisker bending to simulate whisking motions against a peg to investigate the possibility that the 3D mechanics of contact from a single whisker are sufficient for localization in head-centered coordinates...
2016: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/27397106/a-novel-path-to-chronic-proprioceptive-disability-with-oxaliplatin-distortion-of-sensory-encoding
#6
Jacob A Vincent, Krystyna B Wieczerzak, Hanna M Gabriel, Paul Nardelli, Mark M Rich, Timothy C Cope
Persistent neurotoxic side effects of oxaliplatin (OX) chemotherapy, including sensory ataxia, limit the efficacy of treatment and significantly diminish patient quality of life. The common explanation for neurotoxicity is neuropathy, however the degree of neuropathy varies greatly among patients and appears insufficient in some cases to fully account for disability. We recently identified an additional mechanism that might contribute to sensory ataxia following OX treatment. In the present study, we tested whether that mechanism, selective modification of sensory signaling by muscle proprioceptors might result in behavioral deficits in rats...
November 2016: Neurobiology of Disease
https://www.readbyqxmd.com/read/27309215/motor-control-of-fly-feeding
#7
Claire E McKellar
Following considerable progress on the molecular and cellular basis of taste perception in fly sensory neurons, the time is now ripe to explore how taste information, integrated with hunger and satiety, undergo a sensorimotor transformation to lead to the motor actions of feeding behavior. I examine what is known of feeding circuitry in adult flies from more than 250 years of work in larger flies and from newer work in Drosophila. I review the anatomy of the proboscis, its muscles and their functions (where known), its motor neurons, interneurons known to receive taste inputs, interneurons that diverge from taste circuitry to provide information to other circuits, interneurons from other circuits that converge on feeding circuits, proprioceptors that influence the motor control of feeding, and sites of integration of hunger and satiety on feeding circuits...
June 2016: Journal of Neurogenetics
https://www.readbyqxmd.com/read/27304988/neuromodulation-of-limb-proprioceptive-afferents-decreases-apnea-of-prematurity-and-accompanying-intermittent-hypoxia-and-bradycardia
#8
Kalpashri Kesavan, Paul Frank, Daniella M Cordero, Peyman Benharash, Ronald M Harper
BACKGROUND: Apnea of Prematurity (AOP) is common, affecting the majority of infants born at <34 weeks gestational age. Apnea and periodic breathing are accompanied by intermittent hypoxia (IH). Animal and human studies demonstrate that IH exposure contributes to multiple pathologies, including retinopathy of prematurity (ROP), injury to sympathetic ganglia regulating cardiovascular action, impaired pancreatic islet cell and bone development, cerebellar injury, and neurodevelopmental disabilities...
2016: PloS One
https://www.readbyqxmd.com/read/27298354/transmembrane-channel-like-tmc-gene-regulates-drosophila-larval-locomotion
#9
Yanmeng Guo, Yuping Wang, Wei Zhang, Shan Meltzer, Damiano Zanini, Yue Yu, Jiefu Li, Tong Cheng, Zhenhao Guo, Qingxiu Wang, Julie S Jacobs, Yashoda Sharma, Daniel F Eberl, Martin C Göpfert, Lily Yeh Jan, Yuh Nung Jan, Zuoren Wang
Drosophila larval locomotion, which entails rhythmic body contractions, is controlled by sensory feedback from proprioceptors. The molecular mechanisms mediating this feedback are little understood. By using genetic knock-in and immunostaining, we found that the Drosophila melanogaster transmembrane channel-like (tmc) gene is expressed in the larval class I and class II dendritic arborization (da) neurons and bipolar dendrite (bd) neurons, both of which are known to provide sensory feedback for larval locomotion...
June 28, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27184818/a-critical-role-for-piezo2-channels-in-the-mechanotransduction-of-mouse-proprioceptive-neurons
#10
Danny Florez-Paz, Kiran Kumar Bali, Rohini Kuner, Ana Gomis
Proprioceptors are responsible for the conscious sensation of limb position and movement, muscle tension or force, and balance. Recent evidence suggests that Piezo2 is a low threshold mechanosensory receptor in the peripheral nervous system, acting as a transducer for touch sensation and proprioception. Thus, we characterized proprioceptive neurons in the mesencephalic trigeminal nucleus that are involved in processing proprioceptive information from the face and oral cavity. This is a specific population of neurons that produce rapidly adapting mechanically-activated currents that are fully dependent on Piezo2...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27161260/evidence-for-the-involvement-of-asic3-in-sensory-mechanotransduction-in-proprioceptors
#11
Shing-Hong Lin, Yuan-Ren Cheng, Robert W Banks, Ming-Yuan Min, Guy S Bewick, Chih-Cheng Chen
Acid-sensing ion channel 3 (ASIC3) is involved in acid nociception, but its possible role in neurosensory mechanotransduction is disputed. We report here the generation of Asic3-knockout/eGFPf-knockin mice and subsequent characterization of heterogeneous expression of ASIC3 in the dorsal root ganglion (DRG). ASIC3 is expressed in parvalbumin (Pv+) proprioceptor axons innervating muscle spindles. We further generate a floxed allele of Asic3 (Asic3(f/f)) and probe the role of ASIC3 in mechanotransduction in neurite-bearing Pv+ DRG neurons through localized elastic matrix movements and electrophysiology...
2016: Nature Communications
https://www.readbyqxmd.com/read/26863348/neural-responses-to-physical-characteristics-of-a-high-velocity-low-amplitude-spinal-manipulation-effect-of-thrust-direction
#12
William R Reed, Cynthia R Long, Gregory N Kawchuk, Randall S Sozio, Joel G Pickar
STUDY DESIGN: Electrophysiological recordings were obtained from proprioceptors in deep lumbar paraspinal muscles of anesthetized cats during high velocity low amplitude spinal manipulation (HVLA-SM). OBJECTIVE: To determine how thrust direction of an HVLA-SM affects neural input from back musculature. SUMMARY OF BACKGROUND DATA: A clinician's ability to apply the thrust of an HVLA-SM in a specified direction is considered an important component of its optimal delivery...
December 5, 2015: Spine
https://www.readbyqxmd.com/read/26860522/proprioceptive-ability-at-the-lips-and-jaw-measured-using-the-same-psychophysical-discrimination-task
#13
Ellie Frayne, Susan Coulson, Roger Adams, Glen Croxson, Gordon Waddington
In the human face, the muscles and joints that generate movement have different properties. Whereas the jaw is a conventional condyle joint, the facial musculature has neither distinct origin nor insertion points, and the muscles do not contain muscle spindle proprioceptors. This current study aims to compare the proprioceptive ability at the orofacial muscles with that of the temporomandibular joint (TMJ) in 21 neuro-typical people aged between 18 and 65 years. A novel psychophysical task was devised for use with both structures that involved a fixed 30...
June 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/26830369/palisade-endings-are-a-constant-feature-in-the-extraocular-muscles-of-frontal-eyed-but-not-lateral-eyed-animals
#14
Roland Blumer, Barbara Maurer-Gesek, Bernhard Gesslbauer, Michael Blumer, Elisabeth Pechriggl, María A Davis-López de Carrizosa, Anja K Horn, Paul J May, Johannes Streicher, Rosa R de la Cruz, Ángel M Pastor
PURPOSE: To test whether palisade endings are a general feature of mammalian extraocular muscles (EOMs). METHODS: Thirteen species, some frontal-eyed (human, monkey, cat, and ferret), and others lateral-eyed (pig, sheep, calf, horse, rabbit, rat, mouse, gerbil, and guinea pig) were analyzed. Palisade endings were labeled by using different combinations of immunofluorescence techniques. Three-dimensional reconstructions of immunolabeled palisade endings were done...
February 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/26824659/muscle-type-identity-of-proprioceptors-specified-by-spatially-restricted-signals-from-limb-mesenchyme
#15
Sebastian Poliak, Amy L Norovich, Masahito Yamagata, Joshua R Sanes, Thomas M Jessell
The selectivity with which proprioceptive sensory neurons innervate their central and peripheral targets implies that they exhibit distinctions in muscle-type identity. The molecular correlates of proprioceptor identity and its origins remain largely unknown, however. In screens to define muscle-type proprioceptor character, we find all-or-none differences in gene expression for proprioceptors that control antagonistic muscles at a single hindlimb joint. Analysis of three of these genes, cadherin13 (cdh13), semaphorin5a (sema5a), and cartilage-acidic protein-1 (crtac1), reveals expression in proprioceptor subsets that supply muscle groups located at restricted dorsoventral and proximodistal domains of the limb...
January 28, 2016: Cell
https://www.readbyqxmd.com/read/26794680/a-newly-identified-type-of-attachment-cell-is-critical-for-normal-patterning-of-chordotonal-neurons
#16
Naomi Halachmi, Atalya Nachman, Adi Salzberg
This work describes unknown aspects of chordotonal organ (ChO) morphogenesis revealed in post-embryonic stages through the use of new fluorescently labeled markers. We show that towards the end of embryogenesis a hitherto unnoticed phase of cell migration commences in which the cap cells of the ventral ChOs elongate and migrate towards their prospective attachment sites. This migration and consequent cell attachment generates a continuous zigzag line of proprioceptors, stretching from the ventral midline to a dorsolateral position in each abdominal segment...
March 1, 2016: Developmental Biology
https://www.readbyqxmd.com/read/26551544/piezo2-is-the-principal-mechanotransduction-channel-for-proprioception
#17
Seung-Hyun Woo, Viktor Lukacs, Joriene C de Nooij, Dasha Zaytseva, Connor R Criddle, Allain Francisco, Thomas M Jessell, Katherine A Wilkinson, Ardem Patapoutian
Proprioception, the perception of body and limb position, is mediated by proprioceptors, specialized mechanosensory neurons that convey information about the stretch and tension experienced by muscles, tendons, skin and joints. In mammals, the molecular identity of the stretch-sensitive channel that mediates proprioception is unknown. We found that the mechanically activated nonselective cation channel Piezo2 was expressed in sensory endings of proprioceptors innervating muscle spindles and Golgi tendon organs in mice...
December 2015: Nature Neuroscience
https://www.readbyqxmd.com/read/26486370/behavioural-evidence-for-a-visual-and-proprioceptive-control-of-head-roll-in-hoverflies-episyrphus-balteatus
#18
Roman Goulard, Alice Julien-Laferriere, Jérome Fleuriet, Jean-Louis Vercher, Stéphane Viollet
The ability of hoverflies to control their head orientation with respect to their body contributes importantly to their agility and their autonomous navigation abilities. Many tasks performed by this insect during flight, especially while hovering, involve a head stabilization reflex. This reflex, which is mediated by multisensory channels, prevents the visual processing from being disturbed by motion blur and maintains a consistent perception of the visual environment. The so-called dorsal light response (DLR) is another head control reflex, which makes insects sensitive to the brightest part of the visual field...
December 2015: Journal of Experimental Biology
https://www.readbyqxmd.com/read/26451482/multisensory-signaling-shapes-vestibulo-motor-circuit-specificity
#19
Emanuela Basaldella, Aya Takeoka, Markus Sigrist, Silvia Arber
The ability to continuously adjust posture and balance is necessary for reliable motor behavior. Vestibular and proprioceptive systems influence postural adjustments during movement by signaling functionally complementary sensory information. Using viral tracing and mouse genetics, we reveal two patterns of synaptic specificity between brainstem vestibular neurons and spinal motor neurons, established through distinct mechanisms. First, vestibular input targets preferentially extensor over flexor motor pools, a pattern established by developmental refinement in part controlled by vestibular signaling...
October 8, 2015: Cell
https://www.readbyqxmd.com/read/26388836/dynamic-high-cadence-cycling-improves-motor-symptoms-in-parkinson-s-disease
#20
Angela L Ridgel, Robert S Phillips, Benjamin L Walter, Fred M Discenzo, Kenneth A Loparo
RATIONALE: Individuals with Parkinson's disease (PD) often have deficits in kinesthesia. There is a need for rehabilitation interventions that improve these kinesthetic deficits. Forced (tandem) cycling at a high cadence improves motor function. However, tandem cycling is difficult to implement in a rehabilitation setting. OBJECTIVE: To construct an instrumented, motored cycle and to examine if high cadence dynamic cycling promotes improvements in motor function...
2015: Frontiers in Neurology
keyword
keyword
33409
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"