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https://www.readbyqxmd.com/read/28425029/comparison-of-a-novel-formulation-of-abiraterone-acetate-vs-the-originator-formulation-in-healthy-male-subjects-two-randomized-open-label-crossover-studies
#1
Ronald Goldwater, Azra Hussaini, Bill Bosch, Paul Nemeth
BACKGROUND AND OBJECTIVE: Abiraterone acetate is approved for the treatment of metastatic castration-resistant prostate cancer. The originator abiraterone acetate (OAA) formulation is poorly absorbed and exhibits large pharmacokinetic variability in abiraterone exposure. Abiraterone acetate fine particle (AAFP) is a proprietary formulation (using SoluMatrix Fine Particle Technology™) designed to increase the oral bioavailability of abiraterone acetate. Here, we report on two phase I studies in healthy male subjects aged 18-50 years...
April 19, 2017: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/28418540/guideline-acp-and-aafp-recommend-systolic-bp-targets-based-on-history-and-risk-level-in-adults-%C3%A2-%C3%A2-60-years-of-age
#2
Alena Shantsila, Gregory Y H Lip
No abstract text is available yet for this article.
April 18, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28409587/management-of-chronic-pain-and-opioid-misuse-a-position-paper-from-the-aafp
#3
Lisa Hauk
No abstract text is available yet for this article.
April 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28376468/family-physicians-play-integral-role-in-emergency-medicine
#4
Gerald C Banks, Anthony W Gerard, Kim Yu, Kim A Bullock
No abstract text is available yet for this article.
January 2017: Annals of Family Medicine
https://www.readbyqxmd.com/read/28376446/aafp-president-pledges-honest-best-effort-toward-better-future-for-family-physicians
#5
Sheri Porter
No abstract text is available yet for this article.
November 2016: Annals of Family Medicine
https://www.readbyqxmd.com/read/28339076/an-activatable-aptamer-based-fluorescence-probe-for-the-detection-of-hepg2-cells
#6
Zongqiang Lai, Juntao Tan, Ruirong Wan, Jie Tan, Zhenghua Zhang, Zixi Hu, Jieping Li, Wei Yang, Yiwei Wang, Yafeng Jiang, Jian He, Nuo Yang, Xiaoling Lu, Yongxiang Zhao
It is significant to develop a probe with sensitivity and specificity for the detection of cancer cells. The present study aimed to develop an 'activatable' aptamer-based fluorescence probe (AAFP) to detect cancer cells and frozen cancer tissue. This AAFP consisted of two fragments: aptamer TLS11a that targets HepG2 cells, and two short extending complementary DNA sequences with a 5'- and 3'-terminus that make the aptamer in hairpin structure a capable quencher to fluorophore. The ability of the AAFP to bind specifically to cancer cells was assessed using flow cytometry, fluorescence spectroscopy and fluorescence microscopy...
May 2017: Oncology Reports
https://www.readbyqxmd.com/read/28318213/aafp-news-afp-edition
#7
(no author information available yet)
No abstract text is available yet for this article.
March 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/28182607/advisory-committee-on-immunization-practices-recommended-immunization-schedule-for-children-and-adolescents-aged-18-years-or-younger-united-states-2017
#8
Candice L Robinson, José R Romero, Allison Kempe, Cynthia Pellegrini
In October 2016, the Advisory Committee on Immunization Practices (ACIP) approved the Recommended Immunization Schedule for Children and Adolescents Aged 18 Years or Younger-United States, 2017. The 2017 child and adolescent immunization schedule summarizes ACIP recommendations, including several changes from the 2016 immunization schedules, in three figures, and footnotes for the figures. These documents can be found on the CDC immunization schedule website (https://www.cdc.gov/vaccines/schedules/index.html)...
February 10, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28182599/advisory-committee-on-immunization-practices-recommended-immunization-schedule-for-adults-aged-19-years-or-older-united-states-2017
#9
David K Kim, Laura E Riley, Kathleen H Harriman, Paul Hunter, Carolyn B Bridges
In October 2016, the Advisory Committee on Immunization Practices (ACIP) voted to approve the Recommended Adult Immunization Schedule for Adults Aged 19 Years or Older-United States, 2017. The 2017 adult immunization schedule summarizes ACIP recommendations in two figures, footnotes for the figures, and a table of contraindications and precautions for vaccines recommended for adults. These documents are available at https://www.cdc.gov/vaccines/schedules. The full ACIP recommendations for each vaccine can be found at https://www...
February 10, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28145672/aafp-news-afp-edition
#10
(no author information available yet)
No abstract text is available yet for this article.
February 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28135725/pharmacologic-treatment-of-hypertension-in-adults-aged-60-years-or-older-to-higher-versus-lower-blood-pressure-targets-a-clinical-practice-guideline-from-the-american-college-of-physicians-and-the-american-academy-of-family-physicians
#11
Amir Qaseem, Timothy J Wilt, Robert Rich, Linda L Humphrey, Jennifer Frost, Mary Ann Forciea
Description: The American College of Physicians (ACP) and the American Academy of Family Physicians (AAFP) jointly developed this guideline to present the evidence and provide clinical recommendations based on the benefits and harms of higher versus lower blood pressure targets for the treatment of hypertension in adults aged 60 years or older. Methods: This guideline is based on a systematic review of published randomized, controlled trials for primary outcomes and observational studies for harms only (identified through EMBASE, the Cochrane Database of Systematic Reviews, MEDLINE, and ClinicalTrials...
March 21, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28075107/aafp-news-afp-edition
#12
(no author information available yet)
No abstract text is available yet for this article.
January 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28075097/aafp-news-afp-edition
#13
(no author information available yet)
No abstract text is available yet for this article.
December 15, 2016: American Family Physician
https://www.readbyqxmd.com/read/28044476/clinical-research-abstracts-accepted-for-presentation-at-aafp-conference-2016
#14
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/27929278/aafp-news-afp-edition
#15
(no author information available yet)
No abstract text is available yet for this article.
November 15, 2016: American Family Physician
https://www.readbyqxmd.com/read/27929266/aafp-news-afp-edition
#16
(no author information available yet)
No abstract text is available yet for this article.
December 1, 2016: American Family Physician
https://www.readbyqxmd.com/read/27929249/aafp-news-afp-edition
#17
(no author information available yet)
No abstract text is available yet for this article.
November 1, 2016: American Family Physician
https://www.readbyqxmd.com/read/27929230/aafp-news-afp-edition
#18
(no author information available yet)
No abstract text is available yet for this article.
October 15, 2016: American Family Physician
https://www.readbyqxmd.com/read/27929211/aafp-news-afp-edition
#19
(no author information available yet)
No abstract text is available yet for this article.
October 1, 2016: American Family Physician
https://www.readbyqxmd.com/read/27898573/improving-physician-recommendations-for-human-papillomavirus-vaccination-the-role-of-professional-organizations
#20
Yulin Hswen, Melissa B Gilkey, Barbara K Rimer, Noel T Brewer
BACKGROUND: To address low human papillomavirus (HPV) vaccination coverage, the American Academy of Family Physicians (AAFP) and the American Academy of Pediatrics (AAP) have launched national campaigns encouraging physicians to deliver strong HPV vaccine recommendations. We surveyed family physicians and pediatricians to examine the impact of these efforts on physicians' recommendation practices. METHODS: A national sample of family physicians and pediatricians (n = 776) completed our online survey in 2014...
January 2017: Sexually Transmitted Diseases
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