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https://www.readbyqxmd.com/read/28340233/increase-in-drug-overdose-deaths-involving-fentanyl-rhode-island-january-2012-march-2014
#1
Melissa C Mercado, Steven A Sumner, M Bridget Spelke, Michele K Bohm, David E Sugerman, Christina Stanley
Objective.:  This study identified sociodemographic, substance use, and multiple opioid prescriber and dispenser risk factors among drug overdose decedents in Rhode Island, in response to an increase in overdose deaths (ODs) involving fentanyl. Methods.:  This cross-sectional investigation comprised all ODs reviewed by Rhode Island's Office of the State Medical Examiners (OSME) during January 2012 to March 2014. Data for 536 decedents were abstracted from OSME's charts, death certificates, toxicology reports, and Prescription Monitoring Program (PMP) databases...
March 6, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28339555/an-item-bank-for-abuse-of-prescription-pain-medication-from-the-patient-reported-outcomes-measurement-information-system-promis%C3%A2
#2
Paul A Pilkonis, Lan Yu, Nathan E Dodds, Kelly L Johnston, Suzanne M Lawrence, Thomas F Hilton, Dennis C Daley, Ashwin A Patkar, Dennis McCarty
Objective.:  There is a need to monitor patients receiving prescription opioids to detect possible signs of abuse. To address this need, we developed and calibrated an item bank for severity of abuse of prescription pain medication as part of the Patient-Reported Outcomes Measurement Information System (PROMIS ® ). Methods.:  Comprehensive literature searches yielded an initial bank of 5,310 items relevant to substance use and abuse, including abuse of prescription pain medication, from over 80 unique instruments...
October 8, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28339456/in-errata-kratom-the-new-legal-high-on-the-block-the-case-of-an-emerging-opioid-receptor-agonist-with-substance-abuse-potential
#3
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Pain Physician
https://www.readbyqxmd.com/read/28339122/mortality-risk-in-a-nationwide-cohort-of-individuals-with-tic-disorders-and-with-tourette-syndrome
#4
Sandra M Meier, Søren Dalsgaard, Preben B Mortensen, James F Leckman, Kerstin J Plessen
BACKGROUND: Few studies have investigated mortality risk in individuals with tic disorders. METHODS: We thus measured the risk of premature death in individuals with tic disorders and with Tourette syndrome in a prospective cohort study with 80 million person-years of follow-up. We estimated mortality rate ratios and adjusted for calendar year, age, sex, urbanicity, maternal and paternal age, and psychiatric disorders to compare individuals with and without tic disorders...
March 24, 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28338724/sex-differences-in-the-development-of-emotion-circuitry-in-adolescents-at-risk-for-substance-abuse-a-longitudinal-fmri-study
#5
Jillian E Hardee, Lora M Cope, Emily C Munier, Robert C Welsh, Robert A Zucker, Mary M Heitzeg
There is substantial evidence for behavioral sex differences in risk trajectories for alcohol and substance use disorders (SUDs), with internalizing factors such as negative affectivity contributing more to female risk. Because the neural development of emotion circuitry varies between males and females across adolescence, it represents a potential mechanism by which underlying neurobiology contributes to SUD risk. Longitudinal functional magnetic resonance imaging (fMRI) was conducted in males and females (n = 18 each) with a family history of alcohol use disorders starting at ages 8-13yrs...
February 21, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28335616/predictors-of-cd4-health-and-viral-suppression-outcomes-for-formerly-homeless-people-living-with-hiv-aids-in-scattered-site-supportive-housing
#6
Elizabeth A Bowen, James Canfield, Suzanne Moore, Midge Hines, Brent Hartke, Chrissy Rademacher
Stable housing is key to improving health outcomes for people living with HIV/AIDS. Though many formerly homeless HIV positive individuals reside in supportive housing, little research has examined biometric HIV health outcomes for residents of these programs. Through a community-based research partnership, this study analyzed secondary data from a Shelter Plus Care supportive housing program in Cincinnati, Ohio to examine the likelihood of participants achieving a healthy CD4 count (>500 cells/mm(3)) and viral suppression (viral load <200 copies/mL) while in supportive housing and to identify participant characteristics associated with these outcomes...
March 23, 2017: AIDS Care
https://www.readbyqxmd.com/read/28334805/hair-testing-for-drugs-of-abuse-and-new-psychoactive-substances-in-a-high-risk-population
#7
Alberto Salomone, Joseph J Palamar, Enrico Gerace, Daniele Di Corcia, Marco Vincenti
Hundreds of new psychoactive substances (NPS) have emerged in the drug market over the last decade. Few drug surveys in the USA, however, ask about use of NPS, so prevalence and correlates of use are largely unknown. A large portion of NPS use is unintentional or unknown as NPS are common adulterants in drugs like ecstasy/Molly, and most NPS are rapidly eliminated from the body, limiting efficacy of urine, blood and saliva testing. We utilized a novel method of examining prevalence of NPS use in a high-risk population utilizing hair-testing...
March 4, 2017: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/28333533/a-randomized-clinical-trial-of-behavioral-couples-therapy-versus-individually-based-treatment-for-drug-abusing-women
#8
Timothy J O'Farrell, Jeremiah A Schumm, Marie M Murphy, Patrice M Muchowski
OBJECTIVE: Behavioral couples therapy (BCT) is more efficacious than individually-based therapy (IBT) for substance and relationship outcomes among substance use disorder patients. This study compared BCT with IBT for drug-abusing women. METHOD: Sixty-one women, mostly White, late 30s, with primary substance use disorder other than alcohol (74% opioid), and male partners were randomized to 26 sessions over 13 weeks of BCT plus 12-step-oriented IBT (i.e., BCT + IBT) or IBT...
April 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28332947/mothers-with-substance-and-alcohol-abuse-support-through-pregnancy-and-early-infancy
#9
Monica Nordenfors, Ingrid Höjer
This article is about the support given to pregnant women and mothers, at an antenatal and child welfare team in Gothenburg (Sweden), specialised on working with mothers who abuse alcohol and/or other substances. The study consists of interviews with 17 women. The aim of the article is to account for how the women experienced the support they got and how they perceived the impact. The results show the importance for the staff of finding the balance between control and support and of creating a non-judgmental attitude in order to build trusting relationships with the women...
March 23, 2017: Social Work in Health Care
https://www.readbyqxmd.com/read/28332123/self-poisoning-suicide-deaths-in-people-with-bipolar-disorder-characterizing-a-subgroup-and-identifying-treatment-patterns
#10
Ayal Schaffer, Lauren M Weinstock, Mark Sinyor, Catherine Reis, Benjamin I Goldstein, Lakshmi N Yatham, Anthony J Levitt
OBJECTIVE: To characterize self-poisoning suicide deaths in BD compared to other suicide decedents. METHODS: Extracted coroner data from all suicide deaths (n = 3319) in Toronto, Canada from 1998 to 2012. Analyses of demographics, clinical history, recent stressors, and suicide details were conducted in 5 subgroups of suicide decedents: BD self-poisoning, BD other methods, non-BD self-poisoning, non-BD other methods, and unipolar depression self-poisoning. Toxicology results for lethal and present substances were also compared between BD and non-BD self-poisoning subgroups as well as between BD and unipolar depression self-poisoning subgroups...
December 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/28332099/integrated-multisystem-analysis-in-a-mental-health-and-criminal-justice-ecosystem
#11
Erin Falconer, Tal El-Hay, Dimitris Alevras, John P Docherty, Chen Yanover, Alan Kalton, Yaara Goldschmidt, Michal Rosen-Zvi
BACKGROUND: Patients with a serious mental illness often receive care that is fragmented due to reduced availability of or access to resources, and inadequate, discontinuous, and uncoordinated care across health, social services, and criminal justice organizations. This article describes the creation of a multisystem analysis that derives insights from an integrated dataset including patient access to case management services, medical services, and interactions with the criminal justice system...
December 2017: Health & Justice
https://www.readbyqxmd.com/read/28331860/quetiapine-misuse-and-abuse-is-it-an-atypical-paradigm-of-drug-seeking-behavior
#12
REVIEW
Sean Kim, Gayoung Lee, Eric Kim, Hyejin Jung, Jongwha Chang
Recent case reports in medical literatures suggest that more and more second-generation atypical antipsychotics (AAs) have been prescribed for off-label use; quetiapine (Brand name: Seroquel(®)) showed increase in its trend for off-label use. Little is known about the reasons behind this trend, although historical sedative and hypnotic prescription patterns suggest that despite relatively superior safety profiles of quetiapine (especially for movement disorders), it may be used for treating substance abuse disorder...
January 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28330465/the-impact-of-non-response-bias-due-to-sampling-in-public-health-studies-a-comparison-of-voluntary-versus-mandatory-recruitment-in-a-dutch-national-survey-on-adolescent-health
#13
Kei Long Cheung, Peter M Ten Klooster, Cees Smit, Hein de Vries, Marcel E Pieterse
BACKGROUND: In public health monitoring of young people it is critical to understand the effects of selective non-response, in particular when a controversial topic is involved like substance abuse or sexual behaviour. Research that is dependent upon voluntary subject participation is particularly vulnerable to sampling bias. As respondents whose participation is hardest to elicit on a voluntary basis are also more likely to report risk behaviour, this potentially leads to underestimation of risk factor prevalence...
March 23, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28329841/using-latent-class-analysis-to-identify-profiles-of-elder-abuse-perpetrators
#14
Marguerite DeLiema, Jeanine Yonashiro-Cho, Zach D Gassoumis, Yongjie Yon, Ken J Conrad
Objectives: Research suggests that abuser risk factors differ across elder mistreatment types, but abuse interventions are not individualized. To move away from assumptions of perpetrator homogeneity and to inform intervention approaches, this study classifies abusers into subtypes according to their behavior profiles. Method: Data are from the Older Adult Mistreatment Assessment administered to victims by Adult Protective Service (APS) in Illinois. Latent class analysis was used to categorize abusers (N = 336) using victim and caseworker reports on abusers' harmful and supportive behaviors and characteristics...
March 8, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28329723/analysis-of-synthetic-phenethylamine-street-drugs-using-direct-sample-analysis-coupled-to-accurate-mass-time-of-flight-mass-spectrometry
#15
Maura K McGonigal, Joshua A Wilhide, Philip B Smith, Noelle M Elliott, Frank L Dorman
Serious health complications and fatal overdoses have brought phenethylamine, otherwise known as 2C, drug abuse to the public's attention. These compounds are 2C-X series analogs of mescaline. The name "2C" results from the two carbons in the ethyl chain. The substituents on these emerging drugs are constantly changed in order to avoid listing as controlled substances. These synthetic drugs are marketed as having affects similar to LSD and MDMA and are typically consumed sublingually via blotter paper. Twenty-six commercially available standards were analyzed using a direct sample analysis technique coupled to accurate mass time of flight mass spectrometry...
March 8, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28329626/associations-between-indoor-tanning-and-risky-health-related-behaviors-among-high-school-students-in-the-united-states
#16
Stephanie Chapman, Kurt Ashack, Eric Bell, Myra Ann Sendelweck, Robert Dellavalle
Understanding of the associations between indoor tanning and risky health related behaviors such as sexual activity and substance abuse among adolescents across the United States is incomplete. The purpose of this study is to identify risky health related behaviors among high school students utilizing indoor tanning according to region. We analyzed the results from surveys of adolescents in 14 different states administered as part of the Youth Risk Behavior Surveillance System (YRBSS) 2013. Data were collected and analyzed over a 4-month period from January 2016 to April 2016...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28328546/temporal-patterns-and-drug-resistance-in-csf-viral-escape-among-art-experienced-hiv-1-infected-adults
#17
Shibani S Mukerji, Vikas Misra, David Lorenz, Anna M Cervantes-Arslanian, Jennifer Lyons, Spyridon Chalkias, Alysse Wurcel, Deirdre Burke, Nagagopal Venna, Susan Morgello, Igor J Koralnik, Dana Gabuzda
BACKGROUND: Cerebrospinal fluid (CSF) viral escape is an increasingly recognized clinical event among HIV-1-infected adults. We analyzed longitudinal data and drug-resistance mutations to characterize profiles of HIV-1-infected patients on antiretroviral therapy with discordant CSF and plasma HIV-1 RNA levels. METHODS: Forty-one cases of CSF escape defined as detectable CSF HIV-1 RNA when plasma levels were undetectable, or HIV-1 RNA >0.5-log higher in CSF than plasma, were identified from Boston Hospitals and National NeuroAIDS Tissue Consortium (NNTC) from 2005-2016...
March 21, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28328384/the-surgeon-general-s-facing-addiction-report-an-historic-document-for-healthcare
#18
Sharon Levy, J Paul Seale, Victoria A Osborne, Kevin L Kraemer, Daniel P Alford, Jeffrey Baxter, Deborah S Finnell, Hillary Kunins, Alexander Y Walley, David C Lewis, Doreen MacLane-Baeder, Adam J Gordon
The publication of Facing Addiction in America: The Surgeon General's Report on Alcohol, Drugs, and Health presents an historic moment not only for the field of addiction medicine, but also for the United States as a nation. The Board of Directors of the Association for Medical Education and Research in Substance Abuse (AMERSA), on behalf of our organization, would like to express our appreciation of the efforts of Dr. Vivek Murthy and the Surgeon General's Office to publish the first surgeon general's report covering substance misuse and substance use disorders...
March 22, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28328314/from-education-to-practice-addressing-opioid-misuse-through-healthcare-provider-training-a-special-issue-of-saj
#19
Adam J Gordon, John Daniel Harding
Opioid misuse may be ignored by providers who are unwilling or not confident in engaging the complex nature of substance use disorders among their patient populations. Addiction is a complex disease and although providers often are comfortable in identifying, assessing, and treating the complex diseases of their patients, basic knowledge and skills of identification, assessment, and treatment expertise involving opioids for pain, addressing opioid misuse, and treatment of opioid use disorder are lacking. Initiatives to improve knowledge of opioid use, misuse, and opioid use disorder among health care providers are emerging...
March 22, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28328306/integration-and-evaluation-of-substance-abuse-research-education-training-saret-into-a-master-of-social-work-program
#20
Ellen Tuchman, Kathleen Hanley, Madeline Naegle, Frederick More, Sewit Bereket, Marc N Gourevitch
BACKGROUND: The Substance Abuse Research and Education Training (SARET) program is funded by the National Institutes of Drug Abuse in 2006 as a novel approach to spark interest in substance abuse research among medical, dental, nursing, and social work graduate students through a Web-based curriculum and research mentorships. This report presents the initial integration of the intervention in a Master of Social Work (MSW) program, the components of the program, and the mixed-methods evaluation of its effect on students' attitudes towards substance abuse research and treatment...
February 8, 2017: Substance Abuse
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