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https://www.readbyqxmd.com/read/29356414/bidirectional-influences-of-caregiver-utterances-and-supported-joint-engagement-in-children-with-and-without-autism-spectrum-disorder
#1
Kristen Bottema-Beutel, Blair Lloyd, Linda Watson, Paul Yoder
This study examined sequential associations between pairs of caregiver talk and caregiver-child joint engagement categories. Sequential associations quantify the extent to which one event (such as a particular type of caregiver talk) follows another event (such as a particular type of joint engagement) in a pre-specified time window, while controlling for the chance occurrence of the sequence. Although unable to support strong conclusions about causality, the requirement of sequential analysis that key events occur within a close temporal sequence rules out alternative explanation for associations that summary-level correlations cannot...
January 22, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29356292/in-memoriam-dr-jimmie-c-holland
#2
Maggie Watson, Leah Webster
No abstract text is available yet for this article.
January 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29355055/recruiting-ent-and-audiology-patients-into-pharmaceutical-trials-evaluating-the-multi-centre-experience-in-the-uk-and-usa
#3
Victoria A Sanchez, Deborah A Hall, Bonnie Millar, Celia D Escabi, Alice Sharman, Jeannette Watson, Sornaraja Thasma, Peter Harris
OBJECTIVE: Recruiting into clinical trials on time and on target is a major challenge and yet often goes unreported. This study evaluated the adjustment to procedures, recruitment and screening methods in two multi-centre pharmaceutical randomised controlled trials (RCTs) for hearing-related problems in adults. DESIGN: Recruitment monitoring and subsequent adjustment of various study procedures (e.g. eligibility criteria, increasing recruiting sites and recruitment methods) are reported...
January 21, 2018: International Journal of Audiology
https://www.readbyqxmd.com/read/29353635/supporting-prostate-cancer-survivors-in-primary-care-findings-from-a-pilot-trial-of-a-nurse-led-psycho-educational-intervention-prospectiv
#4
Eila K Watson, Bethany Shinkins, Lauren Matheson, Richeal M Burns, Emma Frith, David Neal, Freddie Hamdy, Fiona M Walter, David Weller, Claire Wilkinson, Sara Faithfull, Prasanna Sooriakumaran, Christof Kastner, Christine Campbell, Richard D Neal, Hugh Butcher, Mike Matthews, Rafael Perera, Jane Wolstenholme, Peter W Rose
PURPOSE: This study sought to test the acceptability and feasibility of a nurse-led psycho-educational intervention (NLPI) delivered in primary care to prostate cancer survivors, and to provide preliminary estimates of the effectiveness of the intervention. METHODS: Men who reported an ongoing problem with urinary, bowel, sexual or hormone-related functioning/vitality on a self-completion questionnaire were invited to participate. Participants were randomly assigned to the NLPI plus usual care, or to usual care alone...
February 2018: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/29352543/a-paradigm-shift-in-psychiatric-classification-the-hierarchical-taxonomy-of-psychopathology-hitop
#5
EDITORIAL
Roman Kotov, Robert F Krueger, David Watson
No abstract text is available yet for this article.
February 2018: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
https://www.readbyqxmd.com/read/29351906/edc-impact-molecular-effects-of-developmental-fm-550-exposure-in-wistar-rat-placenta-and-fetal-forebrain
#6
Kylie R Baldwin, Brian Horman, Allison L Phillips, Susan L McRitchie, Scott Watson, Jocelin Deese-Spruill, Dereje Jima, Susan Sumner, Heather Stapleton, Heather Patisaul
Firemaster 550 (FM 550) is a flame retardant (FR) mixture that has become one of the most commonly used FRs in foam-based furniture and baby products. Human exposure to this commercial mixture, comprised of brominated and organophosphate components, is widespread. We have repeatedly shown that developmental exposure can lead to sex-specific behavioral effects in rats. Accruing evidence of endocrine disruption and potential neurotoxicity have raised concerns regarding the neurodevelopmental effects of FM 550 exposure, but the specific mechanisms of action remains unclear...
January 19, 2018: Endocrine Connections
https://www.readbyqxmd.com/read/29351507/-i-smoke-like-this-to-suppress-these-issues-that-are-flaws-of-my-character-challenges-and-facilitators-of-cessation-among-smokers-with-bipolar-disorder
#7
Jaimee L Heffner, Noreen L Watson, Jennifer B McClure, Robert M Anthenelli, Sarah Hohl, Jonathan B Bricker
OBJECTIVE: Smokers with bipolar disorder (BD) have low rates of successful quitting, yet no prior studies have evaluated the process of quitting among these smokers in the context of a current quit attempt. To facilitate development of more effective interventions, we conducted a qualitative exploration of challenges and facilitators of quitting in an intervention study for smokers with BD. METHODS: Participants were adult daily smokers with BD (n = 10) who completed a 10-week smoking cessation intervention consisting of Acceptance and Commitment Therapy (ACT) and nicotine patch...
January 19, 2018: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/29350722/chemical-decontamination-of-ips-cell-derived-neural-cell-mixtures
#8
Di Mao, Xie Khim Watson Chung, Tomoko Andoh-Noda, Ying Qin, Shin-Ichi Sato, Yasushi Takemoto, Wado Akamatsu, Hideyuki Okano, Motonari Uesugi
This report describes the design and evaluation of phosphorylated 7-ethyl-10-hydroxycamptothecin (SN38-P), which selectively eliminates tumor-forming proliferative stem cells, including human induced pluripotent stem cells (hiPSCs) and neural stem cells, from iPSC-derived neural cell mixtures. Results of the present study demonstrate that simple phosphorylation of an anticancer drug can provide a safe, cost-effective, and chemically-defined tool for decontaminating hiPSC-derived neuron.
January 19, 2018: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29350573/feasibility-and-acceptability-of-screening-for-adverse-childhood-experiences-in-prenatal-care
#9
Tracy Flanagan, Amy Alabaster, Brigid McCaw, Nicole Stoller, Carey Watson, Kelly C Young-Wolff
INTRODUCTION: Adverse childhood experiences (ACEs) are common among pregnant women and contribute to increased risk for negative perinatal outcomes, yet few clinicians screen prenatal patients for ACEs. The purpose of this study was to evaluate the feasibility and acceptability of screening for ACEs in standard prenatal care. METHODS: We evaluated a 4-month pilot (March 2016-June 2016) to screen pregnant women (at ∼14-23 weeks of gestation) for ACEs and resiliency in two Kaiser Permanente Northern California medical centers (N = 480)...
January 19, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29350150/role-of-environmental-factors-in-shaping-spatial-distribution-of-salmonella-enterica-serovar-typhi-fiji
#10
Ruklanthi de Alwis, Conall Watson, Birgit Nikolay, John H Lowry, Nga Tran Vu Thieu, Tan Trinh Van, Dung Tran Thi Ngoc, Kitione Rawalai, Mere Taufa, Jerimaia Coriakula, Colleen L Lau, Eric J Nilles, W John Edmunds, Mike Kama, Stephen Baker, Jorge Cano
Fiji recently experienced a sharp increase in reported typhoid fever cases. To investigate geographic distribution and environmental risk factors associated with Salmonella enterica serovar Typhi infection, we conducted a cross-sectional cluster survey with associated serologic testing for Vi capsular antigen-specific antibodies (a marker for exposure to Salmonella Typhi in Fiji in 2013. Hotspots with high seroprevalence of Vi-specific antibodies were identified in northeastern mainland Fiji. Risk for Vi seropositivity increased with increased annual rainfall (odds ratio [OR] 1...
February 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29349854/implementing-health-and-social-care-integration-in-scotland-renegotiating-new-partnerships-in-changing-cultures-of-care
#11
Charlotte Pearson, Nick Watson
Health and social care integration has been a long-term goal for successive governments in Scotland, culminating in the implementation of the recent Public Bodies (Joint Working) Scotland Act 2014. This laid down the foundations for the delegation of health and social care functions and resources to newly formed Integrated Joint Boards. It put in place demands for new ways of working and partnership planning. In this article, we explore the early implementation of this Act and how health and social care professionals and the third sector have begun to renegotiate their roles...
January 18, 2018: Health & Social Care in the Community
https://www.readbyqxmd.com/read/29349696/assessing-priming-for-prosodic-representations-speaking-rate-intonational-phrase-boundaries-and-pitch-accenting
#12
Kristen M Tooley, Agnieszka E Konopka, Duane G Watson
Recent work in the literature on prosody presents a puzzle: Some aspects of prosody can be primed in production (e.g., speech rate), but others cannot (e.g., intonational phrase boundaries, or IPBs). In three experiments we aimed to replicate these effects and identify the source of this dissociation. In Experiment 1 we investigated how speaking rate and the presence of an intonational boundary in a prime sentence presented auditorily affect the production of these aspects of prosody in a target sentence presented visually...
January 18, 2018: Memory & Cognition
https://www.readbyqxmd.com/read/29349406/thrombolytic-therapy-for-critical-limb-ischemia-in-a-jehovah-s-witness-with-severe-anemia
#13
Jeremy D Kauffman, T Joseph Watson, Joseph J Campbell
A patient's refusal to receive blood products can pose both clinical and ethical challenges to the surgeon. In this report, we review the case of a Jehovah's Witness presenting with critical lower limb ischemia and severe anemia for whom the decision of whether to perform thrombolytic therapy was complicated by his refusal to accept blood products. The case demonstrates that thrombolytic therapy can produce favorable results in severely anemic patients even when transfusion is not an option. We conclude that offering thrombolytic therapy in this context is a reasonable therapeutic option from both a clinical and ethical perspective...
September 2017: Journal of Vascular Surgery Cases and Innovative Techniques
https://www.readbyqxmd.com/read/29349385/novel-non-gadolinium-enhanced-magnetic-resonance-imaging-technique-of-pedal-artery-aneurysms
#14
J Devin B Watson, Beatrice Grasu, Rajiv Menon, Raymond Pensy, Robert S Crawford, Taehoon Shin
Non-gadolinium-enhanced magnetic resonance angiography (nMRA) is a noninvasive, contrast-free imaging modality used for visualizing pedal arterial anatomy. We report application of the nMRA technique for detailed arterial imaging in a patient with dorsalis pedis aneurysm. Compared with digital subtraction angiography, we demonstrate that nMRA provides sufficient arterial detail needed to develop a complex operative plan before vascular intervention without risk of contrast agent or ionizing radiation exposure...
June 2017: Journal of Vascular Surgery Cases and Innovative Techniques
https://www.readbyqxmd.com/read/29348925/volume-estimates-in-chronic-hemodialysis-patients-by-the-watson-equation-and-bioimpedance-spectroscopy-and-the-impact-on-the-kt-vurea-calculation
#15
Nazanin Noori, Ron Wald, Arti Sharma Parpia, Marc B Goldstein
Background: Accurate assessment of total body water (TBW) is essential for the evaluation of dialysis adequacy (Kt/Vurea). The Watson formula, which is recommended for the calculation of TBW, was derived in healthy volunteers thereby leading to potentially inaccurate TBW estimates in maintenance hemodialysis recipients. Bioimpedance spectroscopy (BIS) may be a robust alternative for the measurement of TBW in hemodialysis recipients. Objectives: The primary objective of this study was to evaluate the accuracy of Watson formula-derived TBW estimates as compared with TBW measured with BIS...
2018: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/29348647/the-contribution-of-predators-and-scavengers-to-human-well-being
#16
REVIEW
Christopher J O'Bryan, Alexander R Braczkowski, Hawthorne L Beyer, Neil H Carter, James E M Watson, Eve McDonald-Madden
Predators and scavengers are frequently persecuted for their negative effects on property, livestock and human life. Research has shown that these species play important regulatory roles in intact ecosystems including regulating herbivore and mesopredator populations that in turn affect floral, soil and hydrological systems. Yet predators and scavengers receive surprisingly little recognition for their benefits to humans in the landscapes they share. We review these benefits, highlighting the most recent studies that have documented their positive effects across a range of environments...
January 18, 2018: Nature Ecology & Evolution
https://www.readbyqxmd.com/read/29348251/reducing-cardiovascular-disparities-through-community-engaged-implementation-research-a-national-heart-lung-and-blood-institute-workshop-report
#17
George A Mensah, Richard S Cooper, Anna Maria Siega-Riz, Lisa A Cooper, Justin D Smith, C Hendricks Brown, John M Westfall, Elizabeth O Ofili, LeShawndra N Price, Sonia Arteaga, Melissa C Green Parker, Cheryl R Nelson, Bradley J Newsome, Nicole Redmond, Rebecca A Roper, Bettina M Beech, Jada L Brooks, Debra Furr-Holden, Samson Y Gebreab, Wayne H Giles, Regina Smith James, Tené T Lewis, Ali H Mokdad, Kari D Moore, Joseph E Ravenell, Al Richmond, Nancy E Schoenberg, Mario Sims, Gopal K Singh, Anne E Sumner, Roberto P Treviño, Karriem S Watson, M Larissa Avilés-Santa, Jared P Reis, Charlotte A Pratt, Michael M Engelgau, David C Goff, Eliseo J Pérez-Stable
Cardiovascular disparities remain pervasive in the United States. Unequal disease burden is evident among population groups based on sex, race, ethnicity, socioeconomic status, educational attainment, nativity, or geography. Despite the significant declines in cardiovascular disease mortality rates in all demographic groups during the last 50 years, large disparities remain by sex, race, ethnicity, and geography. Recent data from modeling studies, linked micromap plots, and small-area analyses also demonstrate prominent variation in cardiovascular disease mortality rates across states and counties, with an especially high disease burden in the southeastern United States and Appalachia...
January 19, 2018: Circulation Research
https://www.readbyqxmd.com/read/29348221/assessing-nature-s-contributions-to-people
#18
Sandra Díaz, Unai Pascual, Marie Stenseke, Berta Martín-López, Robert T Watson, Zsolt Molnár, Rosemary Hill, Kai M A Chan, Ivar A Baste, Kate A Brauman, Stephen Polasky, Andrew Church, Mark Lonsdale, Anne Larigauderie, Paul W Leadley, Alexander P E van Oudenhoven, Felice van der Plaat, Matthias Schröter, Sandra Lavorel, Yildiz Aumeeruddy-Thomas, Elena Bukvareva, Kirsten Davies, Sebsebe Demissew, Gunay Erpul, Pierre Failler, Carlos A Guerra, Chad L Hewitt, Hans Keune, Sarah Lindley, Yoshihisa Shirayama
No abstract text is available yet for this article.
January 19, 2018: Science
https://www.readbyqxmd.com/read/29348010/early-outcomes-with-the-evolut-pro-repositionable-self-expanding-transcatheter-aortic-valve-with-pericardial-wrap
#19
John K Forrest, Abeel A Mangi, Jeffrey J Popma, Kamal Khabbaz, Michael J Reardon, Neal S Kleiman, Steven J Yakubov, Daniel Watson, Susheel Kodali, Isaac George, Peter Tadros, George L Zorn, John Brown, Robert Kipperman, Sara Saul, Hongyan Qiao, Jae K Oh, Mathew R Williams
OBJECTIVES: This study sought to evaluate the Medtronic Evolut PRO Transcatheter Aortic Valve System in patients with severe symptomatic aortic stenosis. BACKGROUND: A next-generation self-expanding transcatheter aortic valve was designed with an external pericardial wrap with the intent to reduce paravalvular leak while maintaining the benefits of a low-profile, self-expanding, and repositionable supra-annular valve. METHODS: The Medtronic Evolut PRO Clinical Study included 60 patients undergoing transcatheter aortic valve replacement with the Evolut PRO valve at 8 investigational sites in the United States...
January 22, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29346651/bipartite-network-analysis-of-gene-sharings-in-the-microbial-world
#20
Eduardo Corel, Raphaël Méheust, Andrew K Watson, James O McInerney, Philippe Lopez, Eric Bapteste
Extensive microbial gene flows affect how we understand virology, microbiology, medical sciences, genetic modification and evolutionary biology. Phylogenies only provide a narrow view of these gene flows: plasmids and viruses, lacking core genes, cannot be attached to cellular life on phylogenetic trees. Yet viruses and plasmids have a major impact on cellular evolution, affecting both the gene content and the dynamics of microbial communities. Using bipartite graphs that connect up to 149,000 clusters of homologous genes with 8217 related and unrelated genomes, we can in particular show patterns of gene sharing that do not map neatly with the organismal phylogeny...
January 15, 2018: Molecular Biology and Evolution
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