keyword
MENU ▼
Read by QxMD icon Read
search

renal ischemia

keyword
https://www.readbyqxmd.com/read/28209953/-extracorporeal-partial-nephrectomy-under-pharmaco-cold-ischemia-for-renal-cell-carcinoma
#1
A A Gritskevich, I V Miroshkina, S S Piyanikin, Z A Adyrkhayev, Yu A Stepanova, A E Zotikov, A A Teplov, V A Kubyshkin, A Sh Revishvili
AIM: To develop the method for extracorporeal partial nephrectomy under pharmaco-cold ischemia without ureter intersection with orthotopic replantation of renal vessels for RCC. MATERIAL AND METHODS: The study included 37 patients with morphologically confirmed RCC pT1a-Т3bN0M0-1G1-3 with intraparenchymal and central location of the tumor in cases of single kidney, comorbidity of contralateral kidney and kidney on the side of lesion. RESULTS: Mean surgery time was 413...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28209087/the-effect-of-hypericum-perforatum-on-kidney-ischemia-reperfusion-damage
#2
Murat Cakir, Halil Duzova, Işil Baysal, Cemile Ceren Gül, Gülbahar Kuşcu, Fatma Kutluk, Hilal Çakin, Şifanur Şeker, Esranur İlbeği, Seda Uslu, Umut Avci, Samet Demir, Cihan Akinci, Sercan Atli
It has been revealed in recent studies that Hypericum Perforatum (HP) is influential on cancer, inflammatory diseases, bacterial and viral diseases, and has neuroprotective and antioxidant properties. In this study, we investigated the effect of HP, which is known to have antioxidant and anti-inflammatory effects, on kidney I/R damage. Male Sprague-Dawley rats were divided into three groups, and each of the groups had eight rats: The Control Group; the Ischemia/Reperfusion (I/R) Group; and the IR + HP Group which was treated with 50 mg/kg of HP...
November 2017: Renal Failure
https://www.readbyqxmd.com/read/28207510/endovascular-repair-of-bilateral-common-iliac-artery-aneurysms-using-gore-excluder-iliac-branch-endoprosthesis-without-aortobi-iliac-stent-graft-conjunction-a-case-report
#3
Vincenzo Ardita, Alessia Giaquinta, Massimiliano Veroux, Angelo Sanfiorenzo, Carla Virgilio, Giuseppe D'Arrigo, Pierfrancesco Veroux
INTRODUCTION: Bilateral common iliac artery (CIA) aneurysm (CIAA) is a rare entity. In the past decade, different endovascular approaches have been adopted for patients with several comorbidities or unfit for open repair (OR). Recently, the use of iliac branch stent graft has been proposed, resulting in satisfactory patency rates and decrease in morbidity. Currently, according to instruction for use, the iliac branch stent graft is to be used with aortobi-iliac stent graft conjunction...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28205545/octreotide-attenuates-acute-kidney-injury-after-hepatic-ischemia-and-reperfusion-by-enhancing-autophagy
#4
Huiping Sun, Shuangfa Zou, Keith A Candiotti, Yanhua Peng, Qinya Zhang, Weiqiang Xiao, Yiyun Wen, Jiao Wu, Jinfeng Yang
Octreotide exerts a protective effect in hepatic ischemia-reperfusion (HIR) injury. However, whether octreotide preconditioning could also reduce acute kidney injury (AKI) after HIR is unknown. This study was designed to investigate the role of octreotide in AKI after HIR. Male Sprague-Dawley rats were pretreated with octreotide or octreotide combined with 3-methyladenine (autophagy inhibitor, 3MA). Plasma creatinine, inflammation markers (e.g., TNF-α and IL-6 etc.), apoptosis, autophagy and phosphorylation of protein kinase B/mammalian target of rapamycin/p70 ribosomal S6 kinase (Akt/mTOR/p70S6K) in the kidney were measured after 60 minutes of liver ischemia and 24 hours of reperfusion for each rat...
February 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28204833/small-heterodimer-partner-attenuates-hydrogen-peroxide-induced-expression-of-cyclooxygenase-2-and-inducible-nitric-oxide-synthase-by-suppression-of-activator-protein-1-and-nuclear-factor-%C3%AE%C2%BAb-in-renal-proximal-tubule-epithelial-cells
#5
Jung Sun Park, Hoon In Choi, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
The orphan nuclear receptor, small heterodimer partner (SHP), plays a negative regulatory role in innate immune responses and is involved in various inflammatory signaling pathways. In the present study, we aimed to ascertain whether SHP is effective in preventing hydrogen peroxide (H2O2)-induced kidney tubular inflammation and explored the molecular mechanisms underlying the protective effects of SHP. Renal ischemia/reperfusion (I/R) injury was induced in mice by clamping both renal pedicles for 30 min...
March 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28204726/the-role-of-qutenza%C3%A2-topical-capsaicin-8-in-treating-neuropathic-pain-from-critical-ischemia-in-patients-with-end-stage-renal-disease-an-observational-cohort-study
#6
Emma Aitken, Gillian McColl, David Kingsmore
No abstract text is available yet for this article.
February 1, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28203024/-significance-of-renal-filtration-fraction-evaluation-of-renal-artery-stenting-for-atherosclerotic-renal-artery-stenosis-treatment
#7
Q C Feng, X Li, J Y Luan, C M Wang, T R Li
OBJECTIVE: To investigate the significance of filtration fraction (FF) and renal artery stenting in the treatment of atherosclerotic renal artery stenosis. METHODS: In the study, 42 cases of renal artery stenosis were treated with 52 renal artery stent implantation. Percutaneous transluminal renal angioplasty and stent (PTRAS) of the patients' health side kidney, ipsilateral kidney (renal) glomerular filtration rate (GFR), renal effective renal plasma flow effective renal plasma flow (ERPF), kidney filtration fraction changes of preoperative and postoperative serum creatinine (SCR) and the changes in the patients with blood pressure (SBP) and the changes after taking antihypertensive drugs were observed and analyzed...
February 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28202852/association-of-serum-uric-acid-levels-with-leg-ischemia-in-patients-with-peripheral-arterial-disease-after-treatment
#8
Yoko Sotoda, Shigeki Hirooka, Hiroyuki Orita, Ichiro Wakabayashi
AIM: We investigated the relationships of serum uric acid levels with the progression of atherosclerosis in patients with peripheral arterial disease (PAD) after treatment. METHODS: Subjects were male patients diagnosed with PAD. Atherosclerosis at the common carotid artery was evaluated based on its intima-media thickness (IMT). Leg arterial flow was evaluated by measuring ankle-brachial index (ABI) and exercise-induced decrease in ABI. RESULTS: Among various risk factors including age, blood pressure, adiposity, estimated glomerular filtration rate, and blood lipid, blood glucose, uric acid, fibrinogen and C-reactive protein levels, only uric acid levels showed significant correlations with ABI [Pearson's correlation coefficient, -0...
February 15, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28202440/exposure-to-placental-ischemia-impairs-postpartum-maternal-renal-and-cardiac-function-in-rats
#9
Nina D Paauw, Jaap A Joles, Frank T Spradley, Bhavisha Bakrania, Zsuzsanna K Zellenger, Arie Franx, Marianne C Verhaar, Joey P Granger, A Titia Lely
INTRODUCTION: Women with a history of preeclampsia (PE) have an increased risk to develop cardiovascular and renal diseases later in life, but the mechanisms underlying this effect are unknown. In rats, we assessed whether placental ischemia results in long-term effects on the maternal cardiovascular and renal systems using the Reduced Uterine Perfusion Pressure (RUPP) model for PE. METHODS: Sprague-Dawley rats received either a SHAM or RUPP operation at gestational day 14...
February 15, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28198766/the-differential-effect-of-apyrase-treatment-and-hcd39-overexpression-on-chronic-renal-fibrosis-following-ischemia-reperfusion-injury
#10
Veena Roberts, Duncan J Campbell, Bo Lu, Joanne Chia, Peter J Cowan, Karen M Dwyer
BACKGROUND: Renal ischemia reperfusion injury (IRI) leads to acute kidney injury and renal fibrosis. CD39 is a key purinergic enzyme in the hydrolysis of ATP and increased CD39 enzymatic activity protects from acute IRI but its effect on renal fibrosis is not known. METHODS: Using a mouse model of unilateral renal IRI, the effects of increased CD39 activity (using soluble apyrase and mice expressing human CD39 transgene) on acute and chronic renal outcomes were examined...
February 14, 2017: Transplantation
https://www.readbyqxmd.com/read/28197781/sclerosing-mesenteritis-a-systematic-review-of-192-cases
#11
REVIEW
Prabin Sharma, Siddhartha Yadav, Christine Marie Needham, Paul Feuerstadt
INTRODUCTION: Sclerosing mesenteritis includes a spectrum of inflammatory disorders involving the adipose tissue of the bowel mesentery. AIM: To perform a systematic review of previously reported cases of sclerosing mesenteritis (SM) to determine the epidemiology, risk factors, methods of diagnosis, treatment patterns and outcomes for this disease. METHODS: Medline, PubMed, Google Scholar and Cochrane database were searched using keywords mesenteric panniculitis, retractile mesenteritis, mesenteric lipodystrophy and sclerosing mesenteritis...
February 14, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28197727/perioperative-morbidity-oncological-outcomes-and-predictors-of-pt3a-upstaging-for-patients-undergoing-partial-nephrectomy-for-ct1-tumors
#12
Pascal Mouracade, Onder Kara, Julien Dagenais, M J Maurice, R J Nelson, Ercan Malkoc, J H Kaouk
OBJECTIVES: To evaluate perioperative morbidity, oncological outcome and predictors of pT3a upstaging after partial nephrectomy (PN). MATERIALS AND METHODS: Retrospective study of 1042 patients who underwent PN for cT1N0M0 renal cell carcinoma between 2007 and 2015. A total of 113 cT1 patients were upstaged to pT3a, while 929 were staged as pT1. Demographic, perioperative and pathological variables were reviewed. We compared the clinico-pathological characteristics, perioperative morbidity and oncological outcomes between pT3a and pT1 groups...
February 14, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28195189/protective-effect-of-maternal-uteroplacental-insufficiency-on-oxygen-induced-retinopathy-in-offspring-removing-bias-of-premature-birth
#13
Silke Becker, Haibo Wang, Baifeng Yu, Randy Brown, Xiaokun Han, Robert H Lane, M Elizabeth Hartnett
To address the hypothesis that maternal uteroplacental insufficiency (UPI) increases severity of retinopathy of prematurity, we developed a composite rat model of UPI and oxygen-fluctuations and removed premature birth as a confounding factor. Timed-pregnant Sprague-Dawley dams underwent bilateral uterine artery ligation or anesthesia (control) at e19.5. Full-term pups developed in room air (RA) or an oxygen-induced retinopathy (OIR) model. Isolectin-stained retinal flat-mounts were analyzed for percent of areas of avascular/total retina (AVA) and of intravitreal neovascular/total retina (IVNV)...
February 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28194034/high-pressure-carbon-monoxide-preserves-rat-kidney-grafts-from-apoptosis-and-inflammation
#14
Toyofumi Abe, Koji Yazawa, Masayuki Fujino, Ryoichi Imamura, Naoyuki Hatayama, Yoichi Kakuta, Koichi Tsutahara, Masayoshi Okumi, Naotsugu Ichimaru, Jun-Ya Kaimori, Yoshitaka Isaka, Kunihiro Seki, Shiro Takahara, Xiao-Kang Li, Norio Nonomura
Renal ischemia-reperfusion (I/R) injury is unavoidable in kidney transplantation (KTx) and frequently influences both short- and long-term allograft survival. Carbon monoxide (CO) has attracted attention as a medical gas with anti-inflammatory and anti-apoptotic effects. We investigated a new strategy for organ preservation using ex vivo application of high-pressure CO in an experimental rat KTx model. We preserved kidney grafts using a high-pressure chamber filled with mixed gases composed of CO and O2. We found that cold I/R injury resulted in progressive deterioration of renal graft function in University of Wisconsin solution, whereas CO significantly improved renal function...
February 13, 2017: Laboratory Investigation; a Journal of Technical Methods and Pathology
https://www.readbyqxmd.com/read/28191789/attenuation-of-partial-unilateral-ureteral-obstruction-induced-renal-damage-with-hyperbaric-oxygen-therapy-in-a-rat-model
#15
Eyup Burak Sancak, Yusuf Ziya Tan, Hakan Turkon, Coskun Silan
OBJECTIVE: The objective of the present study was to evaluate the effectiveness of HBO therapy on biochemical parameters, renal morphology and renal scintigraphy in rats undergoing chronic unilateral partial ureteral obstruction (UPUO). MATERIAL AND METHODS: Thirty-five rats were divided into five equal groups: Control group; Sham group; HBO group; UPUO group and UPUO/HBO group. The effects of HBO therapy were examined using biochemical parameters and histopathological changes...
January 27, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28188362/comparing-renal-function-preservation-after-laparoscopic-radio-frequency-ablation-assisted-tumor-enucleation-and-laparoscopic-partial-nephrectomy-for-clinical-t1a-renal-tumor-using-a-3d-parenchyma-measurement-system
#16
Liangsong Zhu, Guangyu Wu, Jiwei Huang, Jianfeng Wang, Ruiyun Zhang, Wen Kong, Wei Xue, Yiran Huang, Yonghui Chen, Jin Zhang
PURPOSE: To compare the renal function preservation between laparoscopic radio frequency ablation assisted tumor enucleation and laparoscopic partial nephrectomy. METHODS: Data were analyzed from 246 patients who underwent laparoscopic radio frequency ablation assisted tumor enucleation and laparoscopic partial nephrectomy for solitary cT1a renal cell carcinoma from January 2013 to July 2015. To reduce the intergroup difference, we used a 1:1 propensity matching analysis...
February 10, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28185287/tumor-size-and-invasiveness-matters-for-partial-nephrectomy-external-validation-and-modification-of-the-arterial-based-complexity-score
#17
Maximilian C Kriegmair, Svetlana Hetjens, Philipp Mandel, Jula Wadle, Johannes Budjan, Maurice S Michel, Daniel Pfalzgraf, Nina Wagener
BACKGROUND: Outcome of partial nephrectomy (PN) depends on anatomic features of the renal tumor, which can be assessed by nephrometry scores. The aim was to externally validate and refine the Arterial Based Complexity (ABC) score and to compare it to established systems. METHODS: Tumors of 300 patients undergoing PN were categorized according to the ABC, RENAL, and PADUA score. Size and tumor invasiveness were combined to form the ABCD score. Correlation analysis and multivariate logistic regression was performed to validate and compare the respective scores as predictors of surgical outcome...
February 10, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28184260/perioperative-management-of-left-ventricular-diastolic-dysfunction-and-heart-failure-an-anesthesiologist-s-perspective
#18
REVIEW
Taeha Ryu, Seok-Young Song
Anesthesiologists frequently see asymptomatic patients with diastolic dysfunction or heart failure for various surgeries. These patients typically show normal systolic function but abnormal diastolic parameters in their preoperative echocardiographic evaluations. The symptoms that are sometimes seen are similar to those of chronic obstructive pulmonary disease. Patients with diastolic dysfunction, and even with diastolic heart failure, have the potential to develop a hypertensive crisis or pulmonary congestion...
February 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/28184034/hyperbaric-oxygenation-protects-against-ischemia-reperfusion-injury-in-transplanted-rat-kidneys-by-triggering-autophagy-and-inhibiting-inflammatory-response
#19
Ding-Su Bao, Yu-Ke Wu, Shi-Jie Fu, Guo-You Wang, Si-Jin Yang, Guo-Biao Liang, Zhi-Hui Xie, Song Rong
BACKGROUND Ischemia-reperfusion injury (IRI) is a clinically common pathologic process defined as the inability to improve neuronal function. This study aimed to investigate the pathological mechanism of IRI and to explore effects of hyperbaric oxygenation (HBO) on autophagy and inflammatory response in IRI. MATERIAL AND METHODS Ninety Sprague-Dawley (SD) rats were randomly divided into a Sham group, a kidney transplant group (Trans), and a kidney transplant plus HBO treatment group (Trans+HBO). The kidney was harvested from the donor and transplanted to recipient rats according to a previously reported study...
February 10, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28173878/the-effects-of-glomerular-and-tubular-renal-progenitors-and-derived-extracellular-vesicles-on-recovery-from-acute-kidney-injury
#20
Andrea Ranghino, Stefania Bruno, Benedetta Bussolati, Aldo Moggio, Veronica Dimuccio, Marta Tapparo, Luigi Biancone, Paolo Gontero, Bruno Frea, Giovanni Camussi
BACKGROUND: Mesenchymal stromal cells (MSCs) and renal stem/progenitors improve the recovery of acute kidney injury (AKI) mainly through the release of paracrine mediators including the extracellular vesicles (EVs). Several studies have reported the existence of a resident population of MSCs within the glomeruli (Gl-MSCs). However, their contribution towards kidney repair still remains to be elucidated. The aim of the present study was to evaluate whether Gl-MSCs and Gl-MSC-EVs promote the recovery of AKI induced by ischemia-reperfusion injury (IRI) in SCID mice...
February 7, 2017: Stem Cell Research & Therapy
keyword
keyword
33396
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"