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https://www.readbyqxmd.com/read/28944197/influence-of-corneal-power-on-circumpapillary-retinal-nerve-fiber-layer-and-optic-nerve-head-measurements-by-spectral-domain-optical-coherence-tomography
#1
Kazunori Hirasawa, Nobuyuki Shoji
AIM: To evaluate the influence of corneal power on circumpapillary retinal nerve fiber layer (cpRNFL) and optic nerve head (ONH) measurements by spectral-domain optical coherence tomography (SD-OCT). METHODS: Twenty-five eyes of 25 healthy participants (mean age 23.6±3.6y) were imaged by SD-OCT using horizontal raster scans. Disposable soft contact lenses of different powers (from -11 to +5 diopters including 0 diopter) were worn to induce 2-diopter changes in corneal power...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28942577/peripapillary-retinal-nerve-fiber-layer-thickness-in-preeclampsia-and-eclampsia
#2
Maliheh Arab, Morteza Entezari, Hamidreza Ghamary, Alireza Ramezani, Adele Ashori, Arman Mowlazadeh, Mehdi Yaseri
PURPOSE: To evaluate peripapillary retinal nerve fiber layer (RNFL) thickness during and after pregnancy in pregnant women with preeclampsia or eclampsia and compare it with normotensive pregnant women as controls. METHODS: In a prospective comparative case-control study 35 women (70 eyes) with mild to moderate preeclampsia, 70 women (140 eyes) with severe preeclampsia and eclampsia, and 44 (88 eyes) healthy pregnant women were enrolled in three groups. Peripapillary RNFL thickness in three groups was measured after 28 weeks of pregnancy and 2 months postpartum by using optical coherence tomography...
September 23, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28941529/emerging-applications-of-optical-coherence-tomography-in-pediatric-optic-neuropathies
#3
Sidney M Gospe, M Tariq Bhatti, Mays A El-Dairi
Limited cooperation and attention span often lead to poorly reliable assessments of visual acuity and visual fields in children, making diagnosis and monitoring of pediatric optic neuropathies challenging. As a noninvasive imaging modality, optical coherence tomography (OCT) could offer particular utility in this patient population. OCT provides high-resolution characterization of the optic nerve head, peripapillary retinal nerve fiber layer, and cellular layers of the macula, all of which can be used to assess the severity of optic nerve disease qualitatively and quantitatively...
May 2017: Seminars in Pediatric Neurology
https://www.readbyqxmd.com/read/28938625/predictive-value-of-preoperative-retinal-nerve-fiber-layer-thickness-for-postoperative-visual-recovery-in-patients-with-chiasmal-compression
#4
Jing Zhang, Sunfu Zhang, Yanlin Song, Chenjing Zhu, Min He, Qingqing Ren, Baoyin Shan, Ziqiong Wang, Yunhui Zeng, Jianguo Xu
The aim of this study was to evaluate the predictive role of preoperative retinal nerve fiber layer (RNFL) thickness for postoperative visual recovery in patients with chiasmal compression through performing a meta-analysis. PubMed, EMBASE, Cochrane Library and China National Knowledge Infrastructure were searched for relevant studies. The study and patient characteristics were extracted. Pooled odds ratio (OR) with 95% confidence interval (CI) was calculated to estimate the predictive value of RNFL thickness...
August 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28937877/changes-in-peripapillary-nerve-fiber-layer-thickness-after-adjuvant-stereotactic-radiotherapy-in-patients-with-neovascular-age-related-macular-degeneration
#5
Mahdy Ranjbar, Maximilian Kurz, Annekatrin Holzhey, Dirk Rades, Salvatore Grisanti
PURPOSE: To evaluate the effect of stereotactic radiotherapy (SRT) in conjunction with intravitreal injections (IVI) of anti-vascular endothelial growth factor (anti-VEGF) drugs on peripapillary retinal nerve fiber layer (pRNFL) thickness in patients with neovascular age-related macular degeneration (nAMD). METHODS: This was a retrospective, observational case series of patients with nAMD, who underwent SRT and subsequently had at least 12 months of complete follow-up...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28937823/optic-disc-parameters-of-myopic-children-with-atropine-treatment
#6
Li-Wei Chan, Yi-Ting Hsieh, Wei-Cherng Hsu, Han-Chih Cheng, Elizabeth P Shen
PURPOSE: To characterize optic disc parameters, retinal nerve fiber layer thickness (RNFLT), and the intraocular pressure (IOP) of myopic children under continual topical 0.25% atropine treatment. METHODS: From October 1, 2010 to September 31, 2011, 67 eyes of 35 myopic children were recruited. The children were treated with 0.25% atropine nightly for myopia control. Visual acuity, refraction, IOP, axial length (AL, IOL Master), RNFLT, and optic disc parameters (Stratus OCT) were measured at enrollment and every 2 months...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28934355/study-of-myelin-structure-changes-during-the-nerve-fibers-demyelination
#7
Natalia N Rodionova, Elvin S Allakhverdiev, Georgy V Maksimov
Raman, NMR and EPR spectroscopy and electrophysiology methods were used to investigate the excitability and the packaging of myelin lipid layers and its viscosity during nerve exposure to pronase E. It was established that during exposure of nerve to pronase E the action potential (AP) conduction velocity and the Schwann cell (SC) (or myelin) water ordering increases, but the nerve myelin refractive index and internode incisions numbers decrease. This effect included two periods-short- and long-time period, probably, because the first one depends on SC protein changes and the second one-on the nerve fiber internode demyelination...
2017: PloS One
https://www.readbyqxmd.com/read/28933972/visual-acuity-and-macular-and-peripapillary-thickness-in-high-myopia
#8
Solmaz Abdolrahimzadeh, Francesco Parisi, Andrea Maria Plateroti, Federica Evangelista, Vito Fenicia, Gianluca Scuderi, Santi Maria Recupero
PURPOSE: To investigate best corrected visual acuity (BCVA), and choroidal and retinal thickness values between high myopes without myopic maculopathy and emmetropes. MATERIALS AND METHODS: Case control study where 53 myopes with axial length (AL) above 26 mm without myopic maculopathy and 53 age-matched emmetropes with AL between 21.50 and 24.50 were included as controls. Complete ophthalmological examination and biometry were performed. Choroidal and individual retinal layer thickness maps using spectral domain optical coherence tomography were obtained in the macular and peripapillary area with enhanced depth imaging...
September 21, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28933185/identification-and-distribution-of-the-interstitial-cells-of-cajal-in-the-abomasum-of-goats
#9
Lingling Wang, Yu Liang, Qiusheng Chen, Nisar Ahmed, Feng Wang, Bing Hu, Ping Yang
The interstitial cells of Cajal (ICCs) are regarded as pacemakers and are involved in neurotransmission in the gastrointestinal tract (GIT) of animals. However, limited information is available about the existence of ICCs within the GIT of ruminants. In this study, we investigated the ultrastructural characteristics and distribution of ICCs in goat abomasum using transmission electron microscopy and c-kit immunohistochemistry. Two different kinds of c-kit immunoreactive cells were observed in the abomasum. The first was identified as ICCs, which appeared to be multipolar or bipolar in shape, with some processes...
January 1, 2017: Cell Transplantation
https://www.readbyqxmd.com/read/28931463/severe-streptomycin-ototoxicity-in-the-mouse-utricle-leads-to-a-flat-epithelium-but-the-peripheral-neural-degeneration-is-delayed
#10
Guo-Peng Wang, Ishani Basu, Lisa A Beyer, Hiu Tung Wong, Donald L Swiderski, Shu-Sheng Gong, Yehoash Raphael
The damaged vestibular sensory epithelium of mammals has a limited capacity for spontaneous hair cell regeneration, which largely depends on the transdifferentiation of surviving supporting cells. Little is known about the response of vestibular supporting cells to a severe insult. In the present study, we evaluated the impact of a severe ototoxic insult on the histology of utricular supporting cells and the changes in innervation that ensued. We infused a high dose of streptomycin into the mouse posterior semicircular canal to induce a severe lesion in the utricle...
September 11, 2017: Hearing Research
https://www.readbyqxmd.com/read/28929274/minimally-invasive-posterior-cervical-foraminotomy-for-treatment-of-radiculopathy-an-effective-time-tested-and-cost-efficient-motion-preservation-technique
#11
REVIEW
L Papavero, R Kothe
OBJECTIVE: To relieve foraminal root impingement due to lateral soft disc fragments, bony spurs, or other rarer causes. INDICATIONS: Soft disc fragment whose bulk is >2/3 lateral to the lateral border of the thecal sac. Intraforaminal dorsal bony narrowing of the root canal. Intraforaminal synovial cyst, extra/intradural tumor. CONTRAINDICATIONS: Paramedian and median soft/hard disc protrusions. Kyphosis of the index level. SURGICAL TECHNIQUE: Patient prone in reverse Trendelenburg position with the head fixed in a Mayfield clamp...
September 19, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28929241/assessment-of-peripapillary-choroidal-thickness-in-primary-open-angle-glaucoma-patients-with-choroidal-vascular-prominence
#12
Yong Ju Song, Young Kook Kim, Jin Wook Jeoung, Ki Ho Park
PURPOSE: To investigate the relationship between peripapillary choroidal thickness (PCT) and choroidal vascular prominence (CVP) colocalized with retinal nerve fiber layer (RNFL) defect in primary open-angle glaucoma (POAG) eyes and to evaluate the relationship between PCT and POAG severity. METHODS: In this cross-sectional comparative study, 29 POAG patients with CVP on RNFL imaging (Group A), 70 POAG patients without CVP (Group B) and 63 healthy controls (Group C) were examined...
September 19, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28928966/optical-coherence-tomography-angiography-in-glaucoma-a-mini-review
#13
REVIEW
Kelvin H Wan, Christopher K S Leung
The advent of optical coherence tomography angiography (OCT-A) provides a new opportunity to visualize the retinal vasculature in a non-invasive and dye-free manner which may help identify vascular abnormalities in glaucoma. While a reduction in retinal and optic nerve head vessel densities and blood flow indexes measured by OCT-A has been demonstrated in patients with glaucoma in many studies, it is unclear whether OCT-A provides additional information for the detection and monitoring of glaucoma compared with OCT measurements such as retinal nerve fiber layer thickness, neuroretinal rim width, and ganglion cell inner plexiform layer thickness...
2017: F1000Research
https://www.readbyqxmd.com/read/28926646/vascular-hypoperfusion-in-acute-optic-neuritis-is-a-potentially-new-neurovascular-model-for-demyelinating-diseases
#14
Ta-Ching Chen, Chao-Yuan Yeh, Chao-Wen Lin, Chung-May Yang, Chang-Hao Yang, I-Hung Lin, Pao-Yang Chen, Jung-Yu Cheng, Fung-Rong Hu
PURPOSE: Optic neuritis is highly correlated with multiple sclerosis and is a major cause of acute visual loss and long-term neuronal degeneration. Primary cerebral hypoperfusion has been reported in brain demyelinating diseases. This study investigated whether peripapillary perfusion is changed in patients with acute optic neuritis (AON). METHODS: This three-year cohort study was conducted from September 1 2012, to August 31, 2015. Two hundred and forty-one patients with non-glaucomatous acute optic neuropathy were screened, and 42 non-highly myopic patients who had suffered their first episode of unilaterally idiopathic AON were studied...
2017: PloS One
https://www.readbyqxmd.com/read/28924339/assessment-of-retinal-nerve-fiber-layer-changes-by-cirrus-high-definition-optical-coherence-tomography-in-myopia
#15
Divya Singh, Sanjay K Mishra, Esha Agarwal, Reetika Sharma, Shibal Bhartiya, Tanuj Dada
INTRODUCTION: To evaluate the relationship between retinal nerve fiber layer (RNFL) thickness measured by Cirrus high-definition (HD) optical coherence tomography (OCT) and the axial length and refractive error of the eye. MATERIALS AND METHODS: A total of 100 eyes of 100 healthy subjects (age 20-34 years with M/F ratio of 57/43), comprising 50 eyes with emmetropia [spherical equivalent (SE) 0 D], 25 eyes with moderate myopia (SE between -4 D and -8 D), and 25 eyes with high myopia (SE between -8 D and -12 D) were analyzed in this cross-sectional study...
May 2017: Journal of Current Glaucoma Practice
https://www.readbyqxmd.com/read/28922725/ameliorative-impact-of-morus-alba-leaves-aqueous-extract-against-embryonic-ophthalmic-tissue-malformation-in-streptozotocin-induced-diabetic-rats
#16
Adel M A Assiri, Mohamed E El-Beeh, Ali H Amin, Mohamed Fawzy Ramadan
BACKGROUND: Diabetes mellitus (DM) is becoming a serious threat to human health. Morus alba var. multicaulis (Perr.) Loudon (Moraceae) showed a bright future in DM therapy. OBJECTIVE: The study evaluates the antioxidant activity of Morus alba leaves aqueous extract (MLAE) and antidiabetic properties of MLAE in streptozotocin-induced diabetic rats focusing on the ameliorative effects against embryogenesis defects. MATERIALS AND METHODS: MLAE was assayed for bioactive compounds, and antiradical potential...
September 13, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28915835/macular-retinal-and-choroidal-thickness-in-unilateral-amblyopia-using-swept-source-optical-coherence-tomography
#17
Syunsuke Araki, Atsushi Miki, Katsutoshi Goto, Tsutomu Yamashita, Go Takizawa, Kazuko Haruishi, Yoshiaki Ieki, Junichi Kiryu, Kiyoshi Yaoeda
BACKGROUND: To investigate macular retinal and choroidal thickness in amblyopic eyes compared to that in fellow and normal eyes using swept-source optical coherence tomography (SS-OCT). METHODS: This study examined 31 patients with hyperopic anisometropic amblyopia (6.9 ± 3.8 years, mean ± standard deviation), 15 patients with strabismic amblyopia without anisometropia (7.9 ± 4.2 years), and 24 age-matched controls (7.8 ± 3.3 years). Retinal and choroidal thickness was measured by 3D scans using SS-OCT...
September 15, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28915799/analysis-of-various-factors-affecting-pupil-size-in-patients-with-glaucoma
#18
Ji Woong Park, Bong Hui Kang, Ji Won Kwon, Kyong Jin Cho
BACKGROUND: Pupil size is an important factor in predicting post-operative satisfaction. We assessed the correlation between pupil size, measured by Humphrey static perimetry, and various affecting factors in patients with glaucoma. METHODS: In total, 825 eyes of 415 patients were evaluated retrospectively. Pupil size was measured with Humphrey static perimetry. Comparisons of pupil size according to the presence of glaucoma were evaluated, as were correlations between pupil size and various factors, including age, logMAR best corrected visual acuity (BCVA), retinal nerve fiber layer (RNFL) thickness, spherical equivalent, intraocular pressure, axial length, central corneal thickness, white-to-white, and the kappa angle...
September 16, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28915256/optical-coherence-tomography-angiography-of-the-peripapillary-capillaries-in-primary-open-angle-and-normal-tension-glaucoma
#19
Ryoko Igarashi, Shun Ochiai, Yuta Sakaue, Aki Suetake, Ryu Iikawa, Testuya Togano, Fuuko Miyamoto, Daiki Miyamoto, Takeo Fukuchi
OBJECTIVES: To evaluate the vascular architecture of the radial peripapillary capillaries (RPCs) and its relation with visual function in patients with open-angle glaucoma (OAG) and normal-tension glaucoma using spectral-domain optical coherence tomography (SD-OCT) angiography. SUBJECTS AND METHODS: Clear OCT angiography images of blood vessels in the optic disc and peripapillary retina were obtained from 52 patients (52 eyes) aged 55.42±10.64 (range 28-72) years with primary OAG...
2017: PloS One
https://www.readbyqxmd.com/read/28912848/changes-in-the-anterior-cornea-during-the-early-stages-of-severe-myopia-prior-to-and-following-lasik-as-detected-by-confocal-microscopy
#20
Jinrong Zhao, Jinguo Yu, Liu Υang, Yang Liu, Shaozhen Zhao
The present study aimed to assess the microscopic changes of the epithelium and Bowman's layer under confocal microscopy during the early stages of severe myopia following laser in situ keratomileusis (LASIK). The study comprised 54 patients (54 eyes) with severe myopia and 65 patients (65 eyes) with low and moderate myopia, who underwent LASIK surgery at Tianjin Medical University Eye Hospital (Tianjin, China). In all patients, the epithelium, Bowman's layer and anterior stroma were examined prior to and 1, 7, 30, 90 and 180 days after the surgery, using in vivo confocal microscopy...
October 2017: Experimental and Therapeutic Medicine
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