Agustina Aragón-Daud, Sofía Milagros Oberti De Luca, Sofía Schurmann Vignaga, Pilar Prado, Rosario Figueras, Lucia Lizaso, María Luz González-Gadea, Facundo Manes, Marcelo Cetkovich, Carla Pallavicini, Teresa Torralva, Laura Alethia de la Fuente
BACKGROUND: Cocaine consumption is associated with reduced attentional event-related potentials (ERPs), namely P3a and P3b, indicating bottom-up and top-down deficits respectively. At cognitive level, these impairments are larger for faster routes of administration (e.g., smoked cocaine [SC]) than slower routes (e.g., insufflated cocaine [IC]). Here we assess these ERPs considering the route of cocaine administration. We hypothesized that SC dependent (SCD) would exhibit reduced amplitude of the P3a, while both SCD and IC dependent (ICD) would show reduced amplitude of the P3b...
April 10, 2024: Drug and Alcohol Dependence