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trace element and pregnancy

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https://www.readbyqxmd.com/read/29413109/serum-cobalt-status-during-pregnancy-and-the-risks-of-pregnancy-induced-hypertension-syndrome-a-prospective-birth-cohort-study
#1
Chunmei Liang, Jianqing Wang, Xun Xia, Qunan Wang, Zhijuan Li, Ruiwen Tao, Yiran Tao, Haiyun Xiang, Shilu Tong, Fangbiao Tao
Cobalt (Co) is an essential trace element and has been suggested to be involved in blood pressure regulation, but few studies have focused on serum Co status during pregnancy and the risks of pregnancy-induced hypertension syndrome (PIH). The aim of this study was to prospectively assess the association between serum Co levels during pregnancy and the risks of PIH, and to explore how the maternal Co status contributes to the incidence of PIH. 3260 non-hypertensive women before pregnancy with singleton births in Ma'anShan birth cohort study (MABC) were recruited with the assessment of maternal Co concentrations, additionally, the levels of 7 inflammatory factors and 3 stress factors in placentas were also determined...
March 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29413099/early-pregnancy-maternal-trace-mineral-status-and-the-association-with-adverse-pregnancy-outcome-in-a-cohort-of-australian-women
#2
Rebecca L Wilson, Tina Bianco-Miotto, Shalem Y Leemaqz, Luke E Grzeskowiak, Gustaaf A Dekker, Claire T Roberts
Maternal micronutrient deficiencies in pregnancy can have profound effects on fetal development and pregnancy outcome. Plasma trace minerals including copper, zinc, selenium and iron have been shown to be extremely important in supporting reproduction. We sought to determine whether there is an association between maternal trace mineral status in early pregnancy and pregnancy complications using a prospective cohort study of 1065 pregnant Australian women who were recruited as part of the Screening for Pregnancy Endpoints (SCOPE) study in Adelaide...
March 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29277664/the-altered-platelet-mineral-ratios-in-pregnancy-complicated-with-intrauterine-growth-restriction
#3
Barbara Poniedziałek, Joanna Nowaczyk, Mariola Ropacka-Lesiak, Przemysław Niedzielski, Anna Komosa, Karolina Pańczak, Piotr Rzymski
Altered function of maternal platelets has been evidenced in intrauterine growth restriction (IUGR) but intraplatelet burden of trace elements, factors known to affect platelet activity, remains unknown in IUGR pregnancy. This study assessed the intraplatelet status of Ca, Cu, Mg, Na, K, P, Zn and their ratios (Ca/P, Ca/Mg, Na/K, Cu/Zn) in IUGR pregnancy (n = 35), uncomplicated pregnancy (n = 25) and in non-pregnant females (n = 25). The IUGR group was characterized by the lowest content of Ca, Mg and Zn, and Ca/P ratio (<1...
December 22, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/29206191/the-metal-neurotoxins-an-important-role-in-current-human-neural-epidemics
#4
REVIEW
Keith Schofield
Many published studies have illustrated that several of the present day neurological epidemics (autism, attention deficit disorder, Alzheimer's) cannot be correlated to any single neurotoxicant. However, the present scientific examination of the numerous global blood monitoring databases for adults that include the concentrations of the neurotoxic elements, aluminum (Al), arsenic (As), lead (Pb), manganese (Mn), mercury (Hg), and selenium (Se) clearly indicate that, when considered in combination, for some, the human body may become easily over-burdened...
December 5, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29173484/strontium-and-oxidative-stress-in-normal-pregnancy
#5
Clara Barneo-Caragol, Eduardo Martínez-Morillo, Susana Rodríguez-González, Paloma Lequerica-Fernández, Ignacio Vega-Naredo, Francisco V Álvarez Menéndez
BACKGROUND: Pregnancy brings about metabolic and oxidative changes that involve various trace elements and oxidative stress. Strontium (Sr) is a trace element scarcely studied in this context, although it has been suggested that it may play a role in the pathophysiology of preeclampsia. The main aim of this study was to evaluate Sr concentrations and oxidative status in normal pregnancy. METHODS: The study population included non-pregnant women (n=31), healthy pregnant women in the first (n=50), second (n=51) and third (n=53) trimesters of gestation, and women in postpartum period (n=31)...
January 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29173474/metallothionein-2a-gene-polymorphism-and-trace-elements-in-mother-newborn-pairs-in-the-croatian-population
#6
Ankica Sekovanić, Jasna Jurasović, Martina Piasek, Daria Pašalić, Tatjana Orct, Antonija Sulimanec Grgec, Sandra Stasenko, Karmen Branović Čakanić, Anamarija Jazbec
The main source of exposure for all essential and toxic elements in the general population is diet. In smokers, the main route for cadmium (Cd) and lead (Pb) intake is the inhalation of tobacco smoke. Besides gender, age, nutrition, lifestyle, and physiological conditions such as pregnancy, specific genetic characteristics also influence individual element uptake. Metallothionein MT2 is a cysteine-rich low-weight protein found ubiquitously throughout the body. Specific gene polymorphism may influence MT2 expression and subsequent binding, transfer and organ accumulation of metals, though data on these influences are lacking, especially in human mother-newborn pairs...
January 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29138022/to-which-mixtures-are-french-pregnant-women-mainly-exposed-a-combination-of-the-second-french-total-diet-study-with-the-eden-and-elfe-cohort-studies
#7
T Traoré, A Forhan, V Sirot, M Kadawathagedara, B Heude, M Hulin, B de Lauzon-Guillain, J Botton, M A Charles, A Crépet
Pregnant women and their unborn child are exposed to a large number of substances during pregnancy. Some of these substances may cross the placenta, resulting in exposure of the foetus. There is growing evidence that certain substances could interact to produce a mixture effect. It is therefore essential to identify the main mixtures mothers are exposed to. This study aimed to identify the major mixtures French pregnant women included in EDEN and ELFE cohorts were exposed to, on the basis of the 441 substances analysed in the second French total diet study...
November 11, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29057438/selected-trace-elements-concentrations-in-pregnancy-and-their-possible-role-literature-review
#8
Iwona Lewicka, Rafał Kocyłowski, Mariusz Grzesiak, Zuzanna Gaj, Przemysław Oszukowski, Joanna Suliburska
The aim of this study was to review the role of selected trace elements in pregnancy and fetal development. Citations related to the role of iron (Fe), zinc (Zn), manganese (Mn), copper (Cu) and selenium (Se) during pregnancy were searched in PubMed, Medline, Web of Science, using keywords and MeSH terms. Inadequate supply of trace elements can cause abnormalities of fetal development and predispose a child to disorders later on in life. Trace elements are the key elements of complex enzymes responsible for the modulation of the antioxidant defense system of the organism...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28910945/-nested-case-control-study-on-associated-factors-for-anemia-during-pregnancy
#9
C L Fan, J Y Luo, W J Gong, X Q Liu, S J Zhou, F F Zhang, J Zeng, H X Li, N Feng
Objective: To explore the related factors of anemia during pregnancy and provide scientific evidence for the primary prevention of anemia during pregnancy. Methods: The pregnant women (≤12 pregnant weeks) who received the first pregnancy care in a local medical institution in Hunan province from June 2013 to November 2014 were included in this cohort study, and for them anemia had been excluded by physical examination. Baseline survey and follow up till childbirth were conducted for them. A queue-based nested case-control study (1 ∶ 2) was conducted (380 pregnant women with anemia detected in this study as case group, 760 pregnant women without anemia randomly selected and matched by age, habitual residence during pregnancy as control group...
September 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28855805/correlation-between-serum-trace-elements-and-risk-of-preeclampsia-a-case-controlled-study-in-riyadh-saudi-arabia
#10
Noura Al-Jameil, Hajera Tabassum, Mir Naiman Ali, Mohammed Abdul Qadeer, Farah Aziz Khan, May Al-Rashed
Preeclampsia is a serious medical complication during pregnancy. In response to an increasing number of preeclamptic cases and scarcity of data concerning the interrelation between trace element levels and preeclampsia, we carried out a hospital based case-control study in Riyadh, Saudi Arabia to study the correlation between levels of serum trace elements and risk of preeclampsia. One hundred and twenty pregnant women were enrolled in this study and divided into three groups of 40 each-Control group, HR group (women at high risk of preeclampsia) and PET group (Preeclampsia group)...
September 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28845935/-using-l-and-acetyl-l-carnintines-in-combination-with-clomiphene-citrate-and-antioxidant-complex-for-treating-idiopathic-male-infertility-a-prospective-randomized-trial
#11
RANDOMIZED CONTROLLED TRIAL
V A Bozhedomov, N A Lipatova, G E Bozhedomova, I M Rokhlikov, E V Shcherbakova, R A Komarina
The most common cause of male infertility is idiopathic oligo-, and or astheno-, and /or teratozoospermia. In such cases, anti-estrogens, antioxidants (vitamins and trace elements) or carnitines are used, but the evidence on their effectiveness is inconsistent; there are currently no published studies exploring their concurrent use. AIM: To investigate the efficacy and safety of the L- and acetyl-L-carnitine complex, vitamins A, E, C, selenium, zinc and other antioxidants ("SpermActin" + "More than vitamins") in combination with clomiphene citrate (CC) in managing male idiopathic infertility in the form of oligo, and/or astheno-, and/or teratozoospermia...
July 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28645012/associations-between-toxic-and-essential-trace-elements-in-maternal-blood-and-fetal-congenital-heart-defects
#12
Yanqiu Ou, Michael S Bloom, Zhiqiang Nie, Fengzhen Han, Jinzhuang Mai, Jimei Chen, Shao Lin, Xiaoqing Liu, Jian Zhuang
Prenatal exposure to toxic trace elements, including heavy metals, is an important public health concern. Few studies have assessed if individual and multiple trace elements simultaneously affect cardiac development. The current study evaluated the association between maternal blood lead (Pb), cadmium (Cd), chromium (Cr), copper (Cu), mercury (Hg), and selenium (Se) levels and congenital heart defects (CHDs) in offspring. This hospital-based case-control study included 112 case and 107 control infants. Maternal peripheral blood draw was made during gestational weeks 17-40 and used to determine trace element levels by inductively coupled plasma mass spectrometry...
June 20, 2017: Environment International
https://www.readbyqxmd.com/read/28641718/alterations-in-lipid-profile-zinc-and-copper-levels-and-superoxide-dismutase-activities-in-normal-pregnancy-and-preeclampsia
#13
Pardis Keshavarz, B Fatemeh Nobakht M Gh, Seyed Reza Mirhafez, Mohsen Nematy, Mohsen Azimi-Nezhad, Sedigheh Ayati Afin, Habibollah Esmaily, Leila Pourali, Atieh Mehdizadeh Hakak, Mohammad Soukhtanloo, Masoumeh Mirteimouri, Nayereh Ghomian, Gordon A Ferns
BACKGROUND: Increased oxidative stress (OS) and lipid peroxidation may be involved in the pathogenesis of preeclampsia (PE). We conducted a case-control study to evaluate the levels of plasma lipids and trace elements as well as activity of superoxide dismutase (SOD) in PE. MATERIALS AND METHODS: The study consisted of 100 patients who had been diagnosed with PE and 100 normotensive pregnant women who underwent medical checkups that served as the control group. Lipid profile, zinc (Zn) and copper (Cu) levels and SOD activities were measured in the plasma of all subjects...
June 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28444499/hair-trace-element-and-electrolyte-content-in-women-with-natural-and-in-vitro-fertilization-induced-pregnancy
#14
Anatoly V Skalny, Alexey A Tinkov, Irina Voronina, Olga Terekhina, Margarita G Skalnaya, Yulia Kovas
The objective of the present study was to perform comparative analysis of hair trace element content in women with natural and in vitro fertilization (IVF)-induced pregnancy. Hair trace element content in 33 women with IVF-induced pregnancy and 99 age- and body mass index-matched control pregnant women (natural pregnancy) was assessed using inductively coupled plasma mass spectrometry. The results demonstrated that IVF-pregnant women are characterized by significantly lower hair levels of Cu, Fe, Si, Zn, Ca, Mg, and Ba at p < 0...
April 25, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28441332/pregnant-sheep-in-a-farm-environment-did-not-develop-anaemia
#15
Gabrielle C Musk, Amanda James, Matthew W Kemp, Sara Ritchie, Andrew Ritchie, Michael Laurence
The aim of this study was to document the haematological profile of pregnant ewes throughout gestation. Sheep were divided into three groups (n = 8 per group): non-pregnant, singleton, or twin pregnancy. Blood samples were collected every 14 days from day 55 of gestation for haemoglobin concentration; packed cell volume; total protein; and albumin concentration. On days 55 and 125 of gestation blood was collected for trace element estimation: soluble copper and zinc; glutathione peroxidase (GSHPx); and methylmalonic acid (MMA)...
April 25, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/28384582/dioxins-furans-and-pcbs-in-canadian-human-milk-2008-2011
#16
Dorothea F K Rawn, Amy R Sadler, Valerie A Casey, François Breton, Wing-Fung Sun, Tye E Arbuckle, William D Fraser
Human milk was collected between 2008 and 2011 as part of the Maternal - Infant Research on Environmental Chemicals (MIREC) study that was initiated to establish Canadian national estimates of maternal and infant exposure to a broad suite of environmental contaminants (e.g., persistent organic pollutants [POPs], trace elements, phthalates, etc.). Among the 1017 human milk samples collected, 298 were analysed for polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs)...
October 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28347462/interactions-of-iron-with-manganese-zinc-chromium-and-selenium-as-related-to-prophylaxis-and-treatment-of-iron-deficiency
#17
REVIEW
Geir Bjørklund, Jan Aaseth, Anatoly V Skalny, Joanna Suliburska, Margarita G Skalnaya, Alexandr A Nikonorov, Alexey A Tinkov
Iron (Fe) deficiency is considered as the most common nutritional deficiency. Iron deficiency is usually associated with low Fe intake, blood loss, diseases, poor absorption, gastrointestinal parasites, or increased physiological demands as in pregnancy. Nutritional Fe deficiency is usually treated with Fe tablets, sometimes with Fe-containing multimineral tablets. Trace element interactions may have a significant impact on Fe status. Existing data demonstrate a tight interaction between manganese (Mn) and Fe, especially in Fe-deficient state...
May 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/28335545/reference-values-of-14-serum-trace-elements-for-pregnant-chinese-women-a-cross-sectional-study-in-the-china-nutrition-and-health-survey-2010-2012
#18
Xiaobing Liu, Yu Zhang, Jianhua Piao, Deqian Mao, Yajie Li, Weidong Li, Lichen Yang, Xiaoguang Yang
The development of reference values of trace elements is recognized as a fundamental prerequisite for the assessment of trace element nutritional status and health risks. In this study, a total of 1400 pregnant women aged 27.0 ± 4.5 years were randomly selected from the China Nutrition and Health Survey 2010-2012 (CNHS 2010-2012). The concentrations of 14 serum trace elements were determined by high-resolution inductively coupled plasma mass spectrometry. Reference values were calculated covering the central 95% reference intervals (P2...
March 21, 2017: Nutrients
https://www.readbyqxmd.com/read/28071021/the-effect-of-alcohol-consumption-on-maternal-and-cord-blood-electrolyte-and-trace-element-levels
#19
Anatoly V Skalny, Elena S Berezkina, Elena V Kiyaeva, Inara E Alidzhanova, Andrew R Grabeklis, Alexey A Tinkov
BACKGROUND: Earlier studies demonstrated that alcoholism significantly alters electrolyte and trace element homeostasis. However, the existing data on the interplay between maternal alcohol consumption and fetal trace element status are contradictory. Therefore, the primary objective of the present study was to assess the influence of alcohol consumption on maternal and cord blood trace elements. METHODS: A total of 30 pregnant women (15 women consuming alcohol and 15 controls) were examined...
October 2016: Acta Scientiarum Polonorum. Technologia Alimentaria
https://www.readbyqxmd.com/read/27943108/associations-between-ivf-outcomes-and-essential-trace-elements-measured-in-follicular-fluid-and-urine-a-pilot-study
#20
Mary E Ingle, Michael S Bloom, Patrick J Parsons, Amy J Steuerwald, Pamela Kruger, Victor Y Fujimoto
PURPOSE: A hypothesis-generating pilot study exploring associations between essential trace elements measured in follicular fluid (FF) and urine and in vitro fertilization (IVF) endpoints. METHODS: We recruited 58 women undergoing IVF between 2007 and 2008, and measured cobalt, chromium, copper, manganese, molybdenum, and zinc in FF (n = 46) and urine (n = 45) by inductively coupled plasma mass spectrometry (ICP-MS). We used multivariable regression models to assess the impact of FF and urine trace elements on IVF outcomes, adjusted for age, body mass index, race, and cigarette smoking...
February 2017: Journal of Assisted Reproduction and Genetics
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