Zhihang Yu, Yiqun Chen, Jingjing Li, Chang Chen, Huaxiu Lu, Siyuan Chen, Tingting Zhang, Tianruo Guo, Yonggang Zhu, Jing Jin, Sheng Yan, Huaying Chen
Pathological conditions linked to shear stress have been identified in hematological diseases, cardiovascular diseases, and cancer. These conditions often exhibit significantly elevated shear stress levels, surpassing 1000 dyn/cm2 in severely stenotic arteries. Heightened shear stress can induce mechanical harm to endothelial cells, potentially leading to bleeding and fatal consequences. However, current technology still grapples with limitations, including inadequate flexibility in simulating bodily shear stress environments, limited range of shear stress generation, and spatial and temporal adaptability...
April 17, 2024: Journal of Nanobiotechnology