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Postural orthostatic tachycardia

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https://www.readbyqxmd.com/read/29784553/postural-orthostatic-tachycardia-syndrome-during-pregnancy-a-systematic-review-of-the-literature
#1
REVIEW
Kate Morgan, Catherine Chojenta, Meredith Tavener, Angela Smith, Deb Loxton
PURPOSE: Postural Orthostatic Tachycardia Syndrome is most commonly seen in women of child bearing age, however little is known about its effects in pregnancy. METHOD: A systematic review was conducted in March 2015 and updated in February 2018. Medline, Embase, PsychInfo, CINHAL, and the Cochrane Library were searched from database inception. The ClinicalTrials.gov site and bibliographies were searched. MeSH and Emtree headings and keywords included; Postural Orthostatic Tachycardia Syndrome, Postural Tachycardia Syndrome, and were combined with pregnancy and pregnancy related subject headings and keywords...
May 9, 2018: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/29778304/postural-orthostatic-tachycardia-syndrome-in-children-and-adolescents
#2
REVIEW
Jeffrey R Boris
Postural orthostatic tachycardia syndrome (POTS) affects up to 3,000,000 people in the United States, with at least one-third of them developing POTS before the age of 18. POTS as a disorder is similar in adult and pediatric populations, but there are factors specific to pediatric patients that affect how it presents and how it is experienced that make pediatric POTS different. This review discusses the both the similarities in this population to their adult counterparts and the unique challenges faced by pediatric POTS patients, including management of schooling and education as well as the complex interactions between these pediatric patients and their parents...
May 12, 2018: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/29753556/pharmacotherapy-for-postural-tachycardia-syndrome
#3
REVIEW
Amanda J Miller, Satish R Raj
Postural tachycardia syndrome (POTS) is a disorder characterized by the presence of orthostatic symptoms (including lightheadedness, palpitations, nausea, dyspnea, and tremulousness) as well as excessive upright tachycardia. POTS predominantly affects women of childbearing age. Treating POTS involves a multi-faceted approach using non-pharmacological and pharmacological interventions. There are no pharmacological treatments that are currently United States Food and Drug Administration (FDA) approved for POTS due to lack of randomized controlled trials...
May 4, 2018: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/29705015/evaluation-of-postural-tachycardia-syndrome-pots
#4
REVIEW
Brent P Goodman
The diagnostic evaluation of a patient with suspected postural tachycardia syndrome (POTS) requires a thoughtful diagnostic approach utilizing a careful clinical history and examination, laboratory, and autonomic testing. This article outlines the importance of a thorough history in identifying mechanism of symptom onset, clinical features, associated clinical conditions or disorders, and factors that may result in symptom exacerbation. The clinical examination involves an assessment of pupillary responses, an evaluation for sudomotor and vasomotor signs, and an assessment for joint hypermobility...
April 22, 2018: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/29701190/-relationship-between-unexplained-palpitation-in-children-and-head-up-tilt-test
#5
Tuoyu Gan, Lijia Wu, Runmei Zou, Ping Lin, Fang Li, Hong Yang, Ping Liu, Xiaohui Gong, Cheng Wang
To explore the relationship between unexplained palpitation in children and head-up tilt test (HUTT).
 Methods: A total of 142 children with the main symptom of unexplained palpitation were admitted to the Specialist Out-Patient Clinic of Children's Cardiovascular Disease from Sept. 2008 to Feb. 2017 in the Second Xiangya Hospital, Central South University. Among them, 63 cases were male, 79 cases were female, with the mean age of (10.12±2.88) years old. The detailed history, physical examinations, conventional 12 electrocardiogram, chest X-ray, echocardiography, myocardial enzymes and thyroid function were all examined...
March 28, 2018: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/29696346/orthostatic-intolerance-and-postural-tachycardia-syndrome-new-insights-into-pathophysiology-and-treatment
#6
REVIEW
Mohammed Ruzieh, Blair P Grubb
Orthostatic intolerance is characterized by symptoms of light-headedness or syncope that is provoked upon standing or in an upright posture. It is most commonly caused by postural orthostatic tachycardia syndrome (POTS) or orthostatic hypotension (OH). Its pathophysiology is complex and commonly involves abnormal autonomic nervous system regulation, autoimmunity, a hyperadrenergic state, and hypovolemia. This article reviews the pathophysiology underlying orthostatic intolerance, as well as the current treatment available...
April 25, 2018: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/29687025/autoimmune-postural-orthostatic-tachycardia-syndrome
#7
Mari Watari, Shunya Nakane, Akihiro Mukaino, Makoto Nakajima, Yukiko Mori, Yasuhiro Maeda, Teruaki Masuda, Koutaro Takamatsu, Yanosuke Kouzaki, Osamu Higuchi, Hidenori Matsuo, Yukio Ando
The aim of this study was to evaluate the association between postural orthostatic tachycardia syndrome (POTS) and circulating antiganglionic acetylcholine receptor (gAChR) antibodies. We reviewed clinical assessments of Japanese patients with POTS, and determined the presence of gAChR antibodies in serum samples from those patients. Luciferase immunoprecipitation systems detected anti-gAChR α 3 and β 4 antibodies in the sera from POTS (29%). Antecedent infections were frequently reported in patients in POTS patients...
April 2018: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/29682372/from-postural-orthostatic-tachycardia-syndrome-to-radiologically-isolated-syndrome
#8
Richa Tripathi, Evanthia Bernitsas
Background: Autonomic dysfunction is common in Multiple Sclerosis (MS) patients. Most spinal cord lesions entail some degree of autonomic nervous system dysfunction. MS patients may develop autonomic dysfunction later in their disease course. Methods: We report a patient with no prior history of MS presenting with orthostatic symptoms and diagnosed initially with postural orthostatic tachycardia syndrome (POTS). Four months later, she was diagnosed with radiologically isolated syndrome (RIS)...
2018: Case Reports in Neurological Medicine
https://www.readbyqxmd.com/read/29628432/cognitive-and-psychological-issues-in-postural-tachycardia-syndrome
#9
REVIEW
Vidya Raj, Morwenna Opie, Amy C Arnold
Postural tachycardia syndrome (POTS) is one of the most common forms of chronic orthostatic intolerance. In addition to orthostatic symptoms, many POTS patients report incapacitating cognitive dysfunction or "brain fog" even while lying down or seated. Consistent with these subjective reports, there is accruing objective evidence of specific cognitive difficulties in POTS, with studies showing mild to moderate cognitive impairment using standardized neuropsychological assessment batteries. The precise profile of cognitive dysfunction in POTS patients has been shown to vary among these studies potentially due to the neuropsychological tests used, postural position, comorbidities and length of illness, inclusion of adolescent versus adult patients, and sites of recruitment...
March 27, 2018: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/29618472/angiotensin-ii-type-1-receptor-autoantibodies-in-postural-tachycardia-syndrome
#10
Xichun Yu, Hongliang Li, Taylor A Murphy, Zachary Nuss, Jonathan Liles, Campbell Liles, Christopher E Aston, Satish R Raj, Artur Fedorowski, David C Kem
BACKGROUND: Both the adrenergic and renin-angiotensin systems contribute to orthostatic circulatory homeostasis, which is impaired in postural orthostatic tachycardia syndrome (POTS). Activating autoantibodies to the α1-adrenergic and β1/2-adrenergic receptors have previously been found in sera from patients with POTS. We hypothesized that patients with POTS might also harbor activating autoantibodies to the angiotensin II type 1 receptor (AT1R) independently of antiadrenergic autoimmunity...
April 4, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29588088/the-etiologic-relation-between-disequilibrium-and-orthostatic-intolerance-in-patients-with-myalgic-encephalomyelitis-chronic-fatigue-syndrome
#11
Kunihisa Miwa, Yukichi Inoue
BACKGROUND: Orthostatic intolerance (OI) causes a marked reduction in the activities of daily living in patients with myalgic encephalomyelitis (ME) or chronic fatigue syndrome. Most symptoms of OI are thought to be related to cerebral hypo-perfusion and sympathetic activation. Because postural stability is an essential element of orthostatic tolerance, disequilibrium may be involved in the etiology of OI. METHODS AND RESULTS: The study comprised 44 patients with ME (men, 11 and women, 33; mean age, 37±9 years), who underwent neurological examinations and 10-min standing and sitting tests...
March 24, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29530592/postural-orthostatic-tachycardia-syndrome-pots-in-denmark-increasingly-recognized-or-new-epidemic
#12
Louise Brinth, Kirsten Pors, Jasmina Medic Spahic, Richard Sutton, Artur Fedorowski, Jesper Mehlsen
AIMS: The incidence of Postural Orthostatic Tachycardia Syndrome (POTS) has grown in recent years. Whether this is an emerging epidemic or increasing recognition is unclear. METHODS: We retrospectively examined 8790 tilt-table tests (HUT) performed between 1997 and 2014 in patients with orthostatic intolerance and/or suspected syncope. Tests were reclassified according to the current diagnostic criteria for POTS. The number of POTS diagnoses in proportion to the number of tilt tests performed per year was calculated...
March 3, 2018: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/29529557/vagal-nerve-stimulation-is-beneficial-in-postural-orthostatic-tachycardia-syndrome-and-epilepsy
#13
Zeljka Petelin Gadze, Andreja Bujan Kovac, Ivan Adamec, Nina Milekic, Vlatko Sulentic
No abstract text is available yet for this article.
April 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29523389/postural-tachycardia-syndrome-diagnosis-physiology-and-prognosis
#14
REVIEW
Amy C Arnold, Jessica Ng, Satish R Raj
Postural tachycardia syndrome (POTS) is a heterogeneous clinical syndrome that has gained increasing interest over the past few decades due to its increasing prevalence and clinical impact on health-related quality of life. POTS is clinically characterized by sustained excessive tachycardia upon standing that occurs in the absence of significant orthostatic hypotension and other medical conditions and or medications, and with chronic symptoms of orthostatic intolerance. POTS represents one of the most common presentations of syncope and presyncope secondary to autonomic dysfunction in emergency rooms and in cardiology, neurology, and primary care clinics...
February 28, 2018: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/29519641/postural-tachycardia-syndrome-and-other-forms-of-orthostatic-intolerance-in-ehlers-danlos-syndrome
#15
REVIEW
Maria Roma, Colleen L Marden, Inge De Wandele, Clair A Francomano, Peter C Rowe
OBJECTIVE: To review the association between orthostatic intolerance syndromes and both joint hypermobility and Ehlers-Danlos syndrome, and to propose reasons for identifying hereditary connective tissue disorders in those with orthostatic intolerance in the context of both clinical care and research. METHODS: We searched the published peer-reviewed medical literature for papers reporting an association between joint hypermobility or Ehlers-Danlos syndrome and orthostatic intolerance...
March 5, 2018: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/29519640/emotional-orienting-during-interoceptive-threat-in-orthostatic-intolerance-dysautonomic-contributions-to-psychological-symptomatology-in-the-postural-tachycardia-syndrome-and-vasovagal-syncope
#16
Andrew P Owens, David A Low, Hugo D Critchley, Christopher J Mathias
Cognitive and emotional processes are influenced by interoception (homeostatic somatic feedback), particularly when physiological arousal is unexpected and discrepancies between predicted and experienced interoceptive signals may engender anxiety. Due to the vulnerability for comorbid psychological symptoms in forms of orthostatic intolerance (OI), this study investigated psychophysiological contributions to emotional symptomatology in 20 healthy control participants (13 females, mean age 36 ± 8 years), 20 postural tachycardia syndrome (PoTS) patients (18 females, mean age 38 ± 13 years) and 20 vasovagal syncope (VVS) patients (15 females, mean age 39 ± 12 years)...
January 31, 2018: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/29508112/youth-with-chronic-pain-and-postural-orthostatic-tachycardia-syndrome-pots-treatment-mediators-of-improvement-in-functional-disability
#17
Ashley N Junghans-Rutelonis, Julia R Craner, Chelsea M Ale, Cynthia Harbeck-Weber, Philip R Fischer, Karen E Weiss
Intensive pain rehabilitation programs are effective in increasing functioning for youth with chronic pain (CP). However, the utility of such programs for youth with CP and co-morbid postural orthostatic tachycardia syndrome (POTS) is rarely examined. In addition, studies examining mediators of treatment for CP are sparse. This paper compares treatment outcomes for youth with CP (n = 117) and youth with CP + POTS (n = 118). Additionally, depression and pain catastrophizing were tested as potential mediators of treatment effects...
March 5, 2018: Journal of Clinical Psychology in Medical Settings
https://www.readbyqxmd.com/read/29500811/efficacy-of-propranolol-bisoprolol-and-pyridostigmine-for-postural-tachycardia-syndrome-a-randomized-clinical-trial
#18
Jangsup Moon, Do-Yong Kim, Woo-Jin Lee, Han Sang Lee, Jung-Ah Lim, Tae-Joon Kim, Jin-Sun Jun, Byeongsu Park, Jung-Ick Byun, Jun-Sang Sunwoo, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Ki-Young Jung, Manho Kim, Sang Kun Lee, Kon Chu
Postural tachycardia syndrome (POTS) is a form of dysautonomia which presents with complex symptoms including orthostatic intolerance. Several medications are prescribed for POTS; however, the efficacy of sustained medical treatment has not been well-investigated. Here, we conducted a 2 × 2 factorial design, randomized, clinical trial of a 3-month medical treatment regimen in POTS patients. Patients were randomly allocated to 4 treatment groups (Group 1: propranolol; Group 2: bisoprolol; Group 3: propranolol + pyridostigmine; Group 4: bisoprolol + pyridostigmine)...
March 2, 2018: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/29472161/overview-of-the-management-of-postural-tachycardia-syndrome-in-pregnant-patients
#19
REVIEW
Mohammed Ruzieh, Blair P Grubb
Postural tachycardia syndrome (POTS) is a chronic condition characterized by symptoms of orthostatic intolerance. Pregnancy can cause different physiological changes in cardiovascular parameters, that could have greater impact on POTS patients. In this review, we discuss the management of POTS in the pregnant and obstetric settings.
February 16, 2018: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/29436000/bascule-syndrome-associated-with-syncopal-episodes
#20
José M Martín, Catalina Torres, Pilar Cordero, Sara Sánchez, Liria Terradez, Dolores Ramón
Bascule syndrome is a recently described benign vasomotor dermatosis characterized by Bier anemic spots, cyanosis, and urticaria-like eruption. We report a case of a 13-year-old girl with cutaneous lesions consistent with Bascule syndrome who had had three exercise-related syncopal episodes. It would be recommended to exclude orthostatic intolerance or postural orthostatic tachycardia syndrome when evaluating patients with Bascule syndrome.
March 2018: Pediatric Dermatology
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