keyword
https://read.qxmd.com/read/38618124/analysis-of-approved-dental-teaching-projects-in-the-teaching-practice-research-program-in-8-dental-schools-of-taiwan-from-2018-to-2023
#21
JOURNAL ARTICLE
Chia-Ming Liu, Ni-Yu Su, Yi-Tzu Chen, Chun-Pin Chiang, Chuan-Hang Yu
BACKGROUND/PURPOSE: The teaching practice research program was initiated by Taiwan's Ministry of Education in 2018 to improve medical teaching quality. This study analyzed dental teaching projects conducted under this program from 2018 to 2023. MATERIALS AND METHODS: Data of submitted and approved medical (including dental) teaching projects from 2018 to 2023 were obtained from the annual reports released by the program committee. The annual passing rates were calculated by dividing the number of approved dental teaching projects by the total number of approved medical teaching projects in the category of medical and healthcare sciences in a particular year...
April 2024: Journal of Dental Sciences
https://read.qxmd.com/read/38615250/teleconsultations-in-oral-medicine-dentist-perception-during-the-covid-19-pandemic-in-brazil
#22
JOURNAL ARTICLE
K-M Paiva, S Trezena, D-M Silveira, L-A França, D-R Martelli, A-L Ribeiro, P-R Bonan, H Martelli-Júnior
BACKGROUND: The aim of this study was to describe the perception of dentists from the North macroregion of Minas Gerais, Brazil, users of telediagnosis in Oral Medicine, during the COVID-19 pandemic. MATERIAL AND METHODS: This is a cross-sectional and descriptive study. Data collection was carried out online, between May and October 2022. The information was transferred to the Statistical Package for the Social Sciences for Windows (SPPS)® version 24. RESULTS: The sample consisted of 255 dentists, predominantly female...
April 14, 2024: Medicina Oral, Patología Oral y Cirugía Bucal
https://read.qxmd.com/read/38613220/magnetic-resonance-observation-of-cartilage-repair-tissue-mocart-scores-55-at-6-months-postoperative-predict-ability-to-achieve-patient-acceptable-symptomatic-state-at-minimum-1-year-postoperative-following-autologous-chondrocyte-implantation-for-grade-iv-chondral
#23
JOURNAL ARTICLE
Julia S Retzky, Connor Fletcher, Morgan Rizy, Alissa Burge, Sabrina M Strickland
PURPOSE: The primary aim is to evaluate the relationship between MOCART scores and patient satisfaction, as evaluated by achievement of (1) the Patient Acceptable Symptomatic State (PASS) and (2) the minimal clinically important difference (MCID) for Knee Injury and Osteoarthritis Score Quality of Life (KOOS QoL), for patients undergoing autologous chondrocyte implantation (ACI) for focal Grade IV patellofemoral chondral defects. The secondary aim is to determine the threshold MOCART score which predicts the ability to meet the PASS and the MCID for KOOS QoL...
April 13, 2024: Cartilage
https://read.qxmd.com/read/38611813/new-thiosemicarbazide-derivatives-with-multidirectional-biological-action
#24
JOURNAL ARTICLE
Patryk Lasek, Urszula Kosikowska, Przemysław Kołodziej, Grażyna Kubiak-Tomaszewska, Natalia Krzyżanowska, Tomasz Szostek, Marta Struga, Marcin Feldo, Anna Bogucka-Kocka, Monika Wujec
Over the years, several new medicinal substances have been introduced for the treatment of diseases caused by bacteria and parasites. Unfortunately, due to the production of numerous defense mechanisms by microorganisms and parasites, they still pose a serious threat to humanity around the world. Therefore, laboratories all over the world are still working on finding new, effective methods of pharmacotherapy. This research work aimed to synthesize new compounds derived from 3-trifluoromethylbenzoic acid hydrazide and to determine their biological activity...
March 29, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38607114/cds-based-hydrothermal-photocatalysts-for-complete-reductive-dehalogenation-of-a-chlorinated-propionic-acid-in-water-by-visible-light
#25
JOURNAL ARTICLE
Martina Milani, Michele Mazzanti, Claudia Stevanin, Tatiana Chenet, Giuliana Magnacca, Luisa Pasti, Alessandra Molinari
Cadmium sulfide (CdS)-based photocatalysts are prepared following a hydrothermal procedure (with CdCl2 and thiourea as precursors). The HydroThermal material annealed (CdS-HTa) is crystalline with a band gap of 2.31 eV. Photoelectrochemical investigation indicates a very reducing photo-potential of -0.9 V, which is very similar to that of commercial CdS. CdS-HTa, albeit having similar reducing properties, is more active than commercial CdS in the reductive dehalogenation of 2,2-dichloropropionic acid (dalapon) to propionic acid...
March 26, 2024: Nanomaterials
https://read.qxmd.com/read/38603401/assessing-national-action-through-emergency-paid-leave-to-mitigate-the-impact-of-covid-19-related-school-closures-on-working-families-in-182-countries
#26
JOURNAL ARTICLE
Amy Raub, Jody Heymann
In April 2020, nearly 1.6 billion learners were out of school. While a growing body of literature has documented the detrimental impact of these closures on children, less attention has been devoted to the steps countries took to mitigate the impact of these closures on working families. Paid leave is recognized as an important policy tool to enable working parents the time they need to respond to family needs without risking job or income loss. This article uses a novel data set to assess whether countries had policies in place prior to the pandemic to respond to increased care needs and the extent to which policies were introduced or expanded during the pandemic to fill the gap...
August 2023: Global Social Policy
https://read.qxmd.com/read/38600929/upper-incisor-position-in-the-sagittal-plane-when-smiling-a-photographic-and-cbct-study
#27
JOURNAL ARTICLE
Asunción Bedoya-Valiente, José-María Llamas-Carreras, Francisco Pastor, Juan-Carlos Rodríguez, Eduardo Espinar-Escalona, José-María Barrera-Mora
BACKGROUND: The aim of this study was to analyze the anteroposterior position between the upper incisors (UI) and the soft tissues based on photographs in which the head has been oriented along the Frankfort Horizontal Plane. MATERIAL AND METHODS: Restrospective case-control study carried out by analizing photographic and CBCT images of 109 patientes. The sample was divided into 4 different groups: 21 normocclusive (N), 29 Class II/1st, 29 Class II/2nd y 30 Class III...
March 2024: Journal of Clinical and Experimental Dentistry
https://read.qxmd.com/read/38596132/impact-of-stent-retriever-size-on-clinical-outcomes-in-the-reco-registry
#28
JOURNAL ARTICLE
Yunlong Ding, Xiaoxiao Mao, Lei Bao, Tingting Zhai, Wenjuan Wang, Zhiqun Gu, Yan Liu, Jiali Niu
OBJECTIVE: In the RECO study, we investigated the impact of the operator's choice of stent retriever size on patients with internal carotid artery (ICA) occlusion. METHODS: Data from the RECO Registry, a prospective multicentre study, were utilized. Patients who underwent mechanical thrombectomy (MT) were divided according to the size of the stent into the RECO 4 × 20 group, the RECO 5 × 30 group and the RECO 6 × 30 group...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38595352/analysis-comparing-the-recovery-of-airway-reflexes-and-cognitive-ability-after-sevoflurane-with-desflurane-anesthesia
#29
JOURNAL ARTICLE
Mohammed Wajid Ali Khan, Prajnyananda Das, V Bhavani, Smit Thakkar, Sai Prannoy Nagella, Alok Dubey
INTRODUCTION: Although sevoflurane and desflurane have nearly identical blood-gas solubilities, current research suggests that airway reflexes recover more quickly with desflurane than sevoflurane; however, cognitive function recovery varies substantially. The current study was piloted to appraise the lengths of time needed to recover from anesthesia following desflurane and sevoflurane anesthesia. MATERIALS AND METHODS: A prospective clinical trial was piloted among 70 adult non-obese subjects who underwent elective surgery and were classified I-II by the " American Association of Anesthesiologists (ASA)"...
February 2024: Journal of Pharmacy & Bioallied Sciences
https://read.qxmd.com/read/38595261/-vertebral-fractures-combined-with-prolonged-activated-partial-prothrombin-time-a-case-report
#30
JOURNAL ARTICLE
Xinzhu Bai, Jinhui He, Songsong Lu, Chun Li, Yilin Wang, Jian Xiong
With the development of modern medical standards, autoimmune diseases and their associated successive osteoporosis have received increasing attention in recent years. Patients with autoimmune diseases, due to the characteristics of the disease and the prolonged use of glucocorticoid hormone therapy, may affect the bone formation and bone absorption of the patient, followed by severe successive osteoporosis, thereby increasing the risk of osteoporotic vertebral fractures. Vertebral compression fractures of the spine are common fracture types in patients with osteoporotic fractures...
April 18, 2024: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://read.qxmd.com/read/38592984/clinical-anatomy-of-pulmonary-connections-in-young-people
#31
JOURNAL ARTICLE
Vitalii I Liakhovskyi, Oleh H Krasnov, Ruslan B Lysenko, Anastasiia V Lіakhovska, Tamara V Horodova-Andrieieva, Natalia O Lyakhova, Oksana I Krasnova
OBJECTIVE: Aim: To study the clinical anatomy of the pulmonary ligaments of young people. PATIENTS AND METHODS: Materials and Methods: The study was carried out when performing 28 autopsies of young people aged 25 to 44 years. Methods of dissection of chest organocomplexes, macro-microscopy, morphometry and planimetry, and statistical processing were used. The shape and topography of the pulmonary ligaments was assessed, their area, the localization of lymph nodes was examined...
2024: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://read.qxmd.com/read/38590602/fine-needle-aspiration-cytology-of-lymph-nodes-in-metastatic-cancer-and-lymphoma-our-single-institution-experience
#32
JOURNAL ARTICLE
Sanela Vesnic, Anes Joguncic, Vesna Sarajlic, Mirsad Doric
BACKGROUND: Lymphadenopathy is a common finding in clinical practice. The cause of enlarged nodes on clinical examination alone is challenging and there may be multiple reasons for this enlargement. It may become enlarged due to stimulation by infectious agents or the involvement of metastasis or malignant diseases, such as lymphoma. OBJECTIVE: The aim of the study was to investigate the diagnostic role of fine needle aspiration cytology of lymph nodes in metastatic cancer and lymphoma...
2024: Materia Socio-medica
https://read.qxmd.com/read/38587026/thorax-computed-tomography-ctx-guided-ground-truth-annotation-of-chest-radiographs-cxr-for-improved-classification-and-detection-of-covid-19
#33
JOURNAL ARTICLE
Şükrü Mehmet Ertürk, Tuğçe Toprak, Rana Günöz Cömert, Cemre Candemir, Eda Cingöz, Zeynep Nur Akyol Sari, Celal Caner Ercan, Esin Düvek, Berke Ersoy, Edanur Karapinar, Atadan Tunaci, M Alper Selver
Several data sets have been collected and various artificial intelligence models have been developed for COVID-19 classification and detection from both chest radiography (CXR) and thorax computed tomography (CTX) images. However, the pitfalls and shortcomings of these systems significantly limit their clinical use. In this respect, improving the weaknesses of advanced models can be very effective besides developing new ones. The inability to diagnose ground-glass opacities by conventional CXR has limited the use of this modality in the diagnostic work-up of COVID-19...
April 8, 2024: International Journal for Numerical Methods in Biomedical Engineering
https://read.qxmd.com/read/38585458/transdermal-drug-delivery-systems-a-focused-review-of-the-physical-methods-of-permeation-enhancement
#34
REVIEW
Rifath Sheikh Vaseem, Alison D'cruz, Srishti Shetty, Hafsa -, Aditya Vardhan, Shreya Shenoy R, Shirleen Miriam Marques, Lalit Kumar, Ruchi Verma
The skin is the body's largest organ and serves as a site of administration for various medications. Transdermal drug delivery systems have several advantages over traditional delivery systems. It has both local and systemic therapeutic properties. Controlled plasma drug levels, reduced dosing frequency, and avoidance of hepatic first-pass metabolism are just a few of these systems' advantages. To achieve maximum efficacy, it is critical to understand the kinetics, physiochemical properties of the drug moiety, and drug transport route...
March 2024: Advanced Pharmaceutical Bulletin
https://read.qxmd.com/read/38585246/qualitative-assessment-of-the-experiences-of-transgender-individuals-assigned-female-at-birth-undergoing-gender-affirming-mastectomy-for-the-treatment-of-gender-dysphoria
#35
JOURNAL ARTICLE
Jose G Christiano, Imran Punekar, Alap Patel, Holly A McGregor, Marian Moskow, Elizabeth Anson
PURPOSE: Evaluation and comparison of outcomes following gender-affirming mastectomy have been hindered by the lack of a validated population- and surgery-specific patient-reported outcome measure (PROM). The purpose of this study was to explore the lived experiences of transgender individuals assigned female at birth (AFAB) from before-to-after gender-affirming mastectomy to identify key qualitative themes that might inform the creation of a quantitative PROM in the future. METHODS: Identified candidates were transgender men AFAB, 18-65 years of age (mean±standard deviation: 30...
April 2024: Transgender Health
https://read.qxmd.com/read/38584732/crystal-structure-and-hirshfeld-surface-analysis-of-4-4-di-meth-oxy-biphenyl-3-3-5-5-tetra-carb-oxy-lic-acid-dihydrate
#36
JOURNAL ARTICLE
Thomas Hanauer, Wilhelm Seichter, Monika Mazik
In the crystal of the title compound, C18 H14 O10 ·2H2 O, the arene rings of the biphenyl moiety are tilted at an angle of 24.3 (1)°, while the planes passing through the carboxyl groups are rotated at angles of 8.6 (1) and 7.7 (1)° out of the plane of the benzene ring to which they are attached. The crystal structure is essentially stabilized by O-H⋯O bonds. Here, the carboxyl groups of neighbouring host mol-ecules are connected by cyclic R 2 2 (8) synthons, leading to the formation of a three-dimensional network...
March 1, 2024: Acta Crystallographica. Section E, Crystallographic Communications
https://read.qxmd.com/read/38581527/piezo1-the-new-actor-in-cell-volume-regulation
#37
REVIEW
A Michelucci, L Catacuzzeno
All animal cells control their volume through a complex set of mechanisms, both to counteract osmotic perturbations of the environment and to enable numerous vital biological processes, such as proliferation, apoptosis, and migration. The ability of cells to adjust their volume depends on the activity of ion channels and transporters which, by moving K+ , Na+ , and Cl- ions across the plasma membrane, generate the osmotic gradient that drives water in and out of the cell. In 2010, Patapoutian's group identified a small family of evolutionarily conserved, Ca2+ -permeable mechanosensitive channels, Piezo1 and Piezo2, as essential components of the mechanically activated current that mediates mechanotransduction in vertebrates...
April 6, 2024: Pflügers Archiv: European Journal of Physiology
https://read.qxmd.com/read/38579702/malaria-slide-bank-to-strengthen-and-improve-the-quality-of-malaria-diagnosis-a-national-slide-repository-in-india
#38
JOURNAL ARTICLE
Shrikant Nema, Bina Srivastava, Naseem Ahmad, Supriya Sharma, Anup R Anvikar, Manju Rahi, Amit Sharma, Praveen Kumar Bharti, Nitika Nitika
Malaria elimination is one of the top health care priorities in India, necessitating accessible and accurate diagnosis for effective treatment. A malaria slide bank in India is a collection of quality-controlled malaria-positive and -negative slides and is considered a vital asset for quality diagnosis. The collection of blood samples, preparation of blood smears, staining, quality control, molecular characterizations, and slide validation were carried out according to standard operating procedures in accordance with the WHO reference laboratory...
April 2, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38576849/revisiting-methotrexate-and-phototrexate-zinc15-library-based-derivatives-using-deep-learning-in-silico-drug-design-approach
#39
JOURNAL ARTICLE
Farhan Siddique, Ahmar Anwaar, Maryam Bashir, Sumaira Nadeem, Ravi Rawat, Volkan Eyupoglu, Samina Afzal, Mehvish Bibi, Yousef A Bin Jardan, Mohammed Bourhia
Introduction: Cancer is the second most prevalent cause of mortality in the world, despite the availability of several medications for cancer treatment. Therefore, the cancer research community emphasized on computational techniques to speed up the discovery of novel anticancer drugs. Methods : In the current study, QSAR-based virtual screening was performed on the Zinc15 compound library (271 derivatives of methotrexate (MTX) and phototrexate (PTX)) to predict their inhibitory activity against dihydrofolate reductase (DHFR), a potential anticancer drug target...
2024: Frontiers in Chemistry
https://read.qxmd.com/read/38576603/the-i-gel-%C3%A2-supraglottic-airway-device-compared-to-endotracheal-intubation-as-the-initial-prehospital-advanced-airway-device-a-natural-experiment-during-the-covid-19-pandemic
#40
JOURNAL ARTICLE
Daniel Levi, Joris Hoogendoorn, Shenae Samuels, Lindsay Maguire, Ruben Troncoso, Scott Gunn, Matthew Katz, Christine VanDillen, Susan A Miller, Jay L Falk, Steven H Katz, Linda Papa
OBJECTIVE: Unlike randomized controlled trials, practical real-world studies can offer important information about implementation of prehospital interventions, particularly in community settings where there may be reluctance to adopt new practices. We present the results of a natural experiment that was driven by mandated COVID-19 pandemic-driven shift from endotracheal intubation (ETI) to the i-gel® supraglottic airway (SGA) as a primary advanced airway management device in the prehospital setting to reduce emergency medical services (EMS) personnel exposure to potentially infectious secretions...
April 2024: Journal of the American College of Emergency Physicians open
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