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https://www.readbyqxmd.com/read/28729951/young-children-do-not-require-perceptual-motor-feedback-to-solve-aesop-s-fable-tasks
#1
Rachael Miller, Sarah A Jelbert, Elsa Loissel, Alex H Taylor, Nicola S Clayton
Aesop's Fable tasks-in which subjects drop objects into a water-filled tube to raise the water level and obtain out-of-reach floating rewards -have been used to test for causal understanding of water displacement in both young children and non-human animals. However, a number of alternative explanations for success on these tasks have yet to be ruled out. One hypothesis is that subjects may respond to perceptual-motor feedback: repeating those actions that bring the reward incrementally closer. Here, we devised a novel, forced-choice version of the Aesop's Fable task to assess whether subjects can solve water displacement tasks when this type of feedback is removed...
2017: PeerJ
https://www.readbyqxmd.com/read/28724273/effects-of-inhaled-salbutamol-on-sport-specific-fitness-of-non-asthmatic-football-players
#2
Farzin Halabchi, Mahdi Abarashi, Mohammad Ali Mansournia, Tohid Seifbarghi
In this article, we investigated the effectiveness of inhaled salbutamol withtherapeutic dose on the sport-specific performance of non-asthmatic young football players. In a double-blinded, randomised placebo controlled trial with 2-treatment, 2-period crossover design, twenty participants who were non-asthmatic junior professional football players were randomly allocated to two groups. Fifteen minutes before sport-specific fitness testing, each group randomly received 2 inhalations (200 micrograms) of salbutamol or placebo, respectively...
May 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28719899/the-relationship-between-mmp-2-1306c-t-and-mmp-9-1562c-t-polymorphisms-and-the-risk-and-prognosis-of-t-cell-acute-lymphoblastic-leukemia-in-a-chinese-population-a-case-control-study
#3
Cong-Meng Lin, Yan-Ling Zeng, Min Xiao, Xu-Qiao Mei, Lv-Ying Shen, Meng-Xian Guo, Zhe-Yao Lin, Qi-Fa Liu, Tin Yang
BACKGROUND: T-cell acute lymphoblastic leukemia (T-ALL) is a malignant hematological disease and is often accompanied by a variety of genetic abnormalities. Hence, our study aims to investigate the relationship between MMP-2 -1306C>T and MMP-9 -1562C>T polymorphisms and the risk and prognosis of T-ALL. METHODS: From April 2009 to February 2011, a total of 376 T-ALL patients were chosen as the case group. Meanwhile, 352 healthy people who passed routine health examinations were selected as the control group...
July 18, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28717267/semen-culture-and-the-assessment-of-genitourinary-tract-infections
#4
REVIEW
Michael Solomon, Ralf Henkel
The male factor contributes approximately 50% to infertility-related cases in couples with an estimated 12%-35% of these cases attributable to male genital tract infections. Depending on the nature of the infection, testicular sperm production, sperm transport, and sperm function can be compromised. Yet, infections are potentially treatable causes of infertility. Male genital tract infections are increasingly difficult to detect. Moreover, they often remain asymptomatic ("silent") with the result that they are then passed on to the relevant sexual partner leading to fertilization and pregnancy failure as well as illness of the offspring...
July 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28715986/the-hiv-care-cascade-among-individuals-under-community-supervision-in-baltimore-maryland
#5
Nickolas Zaller, Michael Gordon, Lauri Bazerman, Irene Kuo, Curt Beckwith
An estimated one in seven HIV-infected individuals pass through U.S. correctional facilities each year. Transitioning from correctional to community settings may increase HIV treatment interruptions and increase the risk of continued HIV transmission in the community. This study assessed access to HIV providers in the community, antiretroviral treatment, and viral suppression to inform the development of interventions to improve HIV treatment outcomes among individuals involved in community corrections. The sample included 100 individuals under community supervision (probation or parole) in Baltimore, Maryland...
July 2017: Journal of Correctional Health Care
https://www.readbyqxmd.com/read/28714490/current-diagnostic-approach-and-initial-treatment-patterns-for-renal-colic-in-emergency-department
#6
R Shrestha, Y Bista, A Khan
BACKGROUND: Renal colic is a common clinical presentation in emergency. The goal of this study was to describe the epidemiology, current diagnostic and treatment strategies of ureteric colic in our emergency department. METHODS: This is a retrospective study performed over a six months period of patients with clinically suspected renal colic. Data collected included age, sex, urine analysis, ultrasound studies regarding size, site of the stone and presence of hydronephrosis...
January 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28711188/plan-delivery-quality-assurance-for-cyberknife-statistical-process-control-analysis-of-350-film-based-patient-specific-qas
#7
J Bellec, N Delaby, F Jouyaux, M Perdrieux, J Bouvier, S Sorel, O Henry, C Lafond
PURPOSE: Robotic radiosurgery requires plan delivery quality assurance (DQA) but there has never been a published comprehensive analysis of a patient-specific DQA process in a clinic. We proposed to evaluate 350 consecutive film-based patient-specific DQAs using statistical process control. We evaluated the performance of the process to propose achievable tolerance criteria for DQA validation and we sought to identify suboptimal DQA using control charts. METHODS AND MATERIAL: DQAs were performed on a CyberKnife-M6 using Gafchromic-EBT3 films...
July 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28708868/dynamics-of-tactical-behaviour-in-association-football-when-manipulating-players-space-of-interaction
#8
Angel Ric, Carlota Torrents, Bruno Gonçalves, Lorena Torres-Ronda, Jaime Sampaio, Robert Hristovski
The analysis of positional data in association football allows the spatial distribution of players during matches to be described in order to improve the understanding of tactical-related constraints on the behavioural dynamics of players. The aim of this study was to identify how players' spatial restrictions affected the exploratory tactical behaviour and constrained the perceptual-motor workspace of players in possession of the ball, as well as inter-player passing interactions. Nineteen professional outfield male players were divided into two teams of 10 and 9 players, respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28704286/the-effect-of-force-feedback-in-a-virtual-learning-environment-on-the-performance-and-satisfaction-of-dental-students
#9
Ilse R de Boer, Maxim D Lagerweij, Merlijn W de Vries, Paul R Wesselink, Johanna M Vervoorn
INTRODUCTION: This study investigated the effect of force feedback (FFB) on student performance in a virtual learning environment (VLE) using the Simodont dental trainer (Moog, Nieuw-Vennep, the Netherlands) and evaluated the students' satisfaction with and without FFB. METHODS: The Simodont dental trainer, which was used as a VLE, was randomly assigned to 101 first-year dental students with no previous experience in cutting a tooth or working in a VLE with FFB...
April 2017: Simulation in Healthcare: Journal of the Society for Simulation in Healthcare
https://www.readbyqxmd.com/read/28695270/maternal-use-of-prednisolone-is-unlikely-to-be-associated-with-neonatal-adrenal-suppression-a-single-center-study-of-16-cases
#10
Leanne de Vetten, Margriet van Stuijvenberg, Ido P Kema, Gianni Bocca
The use of supra-physiological, exogenous corticosteroids in pregnancy may lead to neonatal adrenal suppression. We report on a single-center, case series study carried out between 2006 and 2014, which included all newborns (n = 16) of mothers using prednisolone ≥10 mg/day during pregnancy. Newborns were routinely assessed according to hospital protocol, with follow-up until 6 weeks after birth. We investigated the clinical symptoms and biochemical findings of adrenal suppression occurring in the newborns...
July 10, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28694734/case-report-of-unexplained-hypocalcaemia-in-a-slightly-haemolysed-sample
#11
Michael Cornes
The case presented highlights a common pre-analytical problem identified in the laboratory that was initially missed. It concerns a young, generally healthy adult patient with no significant medical history and no significant family history. They presented with common flu like symptoms to their primary care clinician who considered this was most likely a viral problem that would pass with time. The clinician, however, did some routine bloods to reassure the patient despite a lack of clinical indication. When the sample was analysed the sample was haemolysed with strikingly low calcium...
June 15, 2017: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/28693050/long-term-results-of-fixation-free-incisional-hernia-repair-using-a-tentacle-shaped-implant
#12
Giuseppe Amato, Giorgio Romano, Thorsten Goetze, Luca Gordini, Enrico Erdas, Fabio Medas, Piergiorgio Calò
INTRODUCTION: The fixation and the overlap of the mesh represent an open issue in incisional hernia repair. An exclusively designed prosthesis has been developed to assure a suture-free repair and a broader coverage of the abdominal wall. This study describes the long-term results of incisional hernia procedures carried out positioning a tentacle-shaped implant through a specifically developed surgical technique. MATERIALS AND METHODS: A proprietary symmetrically-shaped flat mesh constituted by a large central body with integrated radiating arms was used to repair incisional hernias in 68 patients...
July 11, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28690176/evaluation-of-the-current-guidelines-for-resection-of-hepatocellular-carcinoma-using-the-appraisal-of-guidelines-research-and-evaluation-ii-instrument
#13
Pascal Gavriilidis, Keith J Roberts, Alan Askari, Robert P Sutcliffe, Teh-la Huo, Po-Hong Liu, Ernest Hidalgo, Philippe Compagnon, Chetana Lim, Daniel Azoulay
BACKGROUND & AIMS: Numerous guidelines for the management of HCC have been developed. The AGREE II is the only validated instrument to assess the methodological quality of guidelines. We aim to appraise the methodological quality of existing guidelines for the resection of hepatocellular carcinoma (HCC) using the Appraisal of Guidelines for Research & Evaluation (AGREE II) instrument. METHODS: Cochrane, Medline, Google scholar and Embase were searched using both PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) criteria and free text...
July 6, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28689268/successful-removal-of-an-internal-pancreatic-stent-that-migrated-into-the-bile-duct-using-double-balloon-enteroscopy-after-pancreaticoduodenectomy
#14
Seiko Hirono, Manabu Kawai, Yasunobu Yamashita, Ken-Ichi Okada, Motoki Miyazawa, Masaki Ueno, Yoshimasa Maeda, Masahiro Itonaga, Masayuki Kitano, Hiroki Yamaue
PURPOSE: Internal stents used during pancreaticoduodenectomy (PD) are generally spontaneously passed through the rectum by defecation. However, we encountered six patients with internal stents that migrated into the bile duct after PD. We herein report the outcomes of these six patients and the usefulness of double-balloon enteroscopy (DBE) for removal of such stents from the bile duct. METHODS: An internal stent was placed across pancreaticojejunostomy in 416 (68...
July 8, 2017: Surgery Today
https://www.readbyqxmd.com/read/28682570/-a-variant-of-the-classic-technique-of-ultrasound-guided-percutaneous-renal-biopsy-the-perpendicular-entry-by-longitudinal-viewing-planes-with-a-perforated-probe
#15
Simone Brardi, Gabriele Cevenini, Angelo Giovanni Bonadio, Roberto Ponchietti, Marcello Caremani, Ennio Duranti
The percutaneous biopsy of native kidneys according to the classic methodology, takes place with the introduction of the needle and its guide with ultrasound sagittal viewing planes, with a 30-degree angle, up to the lower pole of the kidney. Since the longitudinal axis of the kidneys converges towards the spine with a sharp angle, we observed that starting from a longitudinal scan of the kidney (conducted along the posterior axillary line with the patient prone) you can drive the needle by a perforated probe through a shorter path perpendicular to the end section of the lower pole of the kidney where the front and rear rims of the cortex bearings without the renal sinus interposed so increasing the chance to obtain, even with a single pass, a good sample of cortical tissue while limiting the possibility to damage the lower chalices that may cause hematuria...
April 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28682134/brain-targeted-delivery-of-mucoadhesive-thermosensitive-nasal-gel-of-selegiline-hydrochloride-for-treatment-of-parkinson-s-disease
#16
Vinay Sridhar, Sarika Wairkar, Ram Gaud, Amrita Bajaj, Pramod Meshram
Selegiline hydrochloride (SL), is an Anti-Parkinson's agent, has low oral bioavailability due to its high first pass metabolism and scarce oral absorption. In the present study, SL mucoadhesive nasal thermosensitive gel (SNT-gel) was prepared to enhance the bioavailability and subsequently, its concentration in the brain. The SNT-gel was prepared using Poloxamer 407-Chitosan combination and optimized formulation was further evaluated for physicochemical parameters. The comparative pharmacodynamic studies including behavioral studies, biochemical testing and histopathology of the brain was carried out in rats for SNT-gel, SL-nasal solution and SL Marketed Tablets...
July 6, 2017: Journal of Drug Targeting
https://www.readbyqxmd.com/read/28677051/development-of-a-reliable-simulation-based-test-for-diagnostic-abdominal-ultrasound-with-a-pass-fail-standard-usable-for-mastery-learning
#17
Mia L Østergaard, Kristina R Nielsen, Elisabeth Albrecht-Beste, Lars Konge, Michael B Nielsen
BACKGROUND: This study aimed to develop a test with validity evidence for abdominal diagnostic ultrasound with a pass/fail-standard to facilitate mastery learning. METHOD: The simulator had 150 real-life patient abdominal scans of which 15 cases with 44 findings were selected, representing level 1 from The European Federation of Societies for Ultrasound in Medicine and Biology. Four groups of experience levels were constructed: Novices (medical students), trainees (first-year radiology residents), intermediates (third- to fourth-year radiology residents) and advanced (physicians with ultrasound fellowship)...
July 4, 2017: European Radiology
https://www.readbyqxmd.com/read/28676834/exponentially-modified-peak-functions-in-biomedical-sciences-and-related-disciplines
#18
A Golubev
In many cases relevant to biomedicine, a variable time, which features a certain distribution, is required for objects of interest to pass from an initial to an intermediate state, out of which they exit at random to a final state. In such cases, the distribution of variable times between exiting the initial and entering the final state must conform to the convolution of the first distribution and a negative exponential distribution. A common example is the exponentially modified Gaussian (EMG), which is widely used in chromatography for peak analysis and is long known as ex-Gaussian in psychophysiology, where it is applied to times from stimulus to response...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28676655/non-darcy-interfacial-dynamics-of-air-water-two-phase-flow-in-rough-fractures-under-drainage-conditions
#19
Chun Chang, Yang Ju, Heping Xie, Quanlin Zhou, Feng Gao
Two-phase flow interfacial dynamics in rough fractures is fundamental to understanding fluid transport in fractured media. The Haines jump of non-Darcy flow in porous media has been investigated at pore scales, but its fundamental processes in rough fractures remain unclear. In this study, the micron-scale Haines jump of the air-water interface in rough fractures was investigated under drainage conditions, with the air-water interface tracked using dyed water and an imaging system. The results indicate that the interfacial velocities represent significant Haines jumps when the meniscus passes from a narrow "throat" to a wide "body", with jump velocities as high as five times the bulk drainage velocity...
July 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28676563/melatonin-mediates-vasodilation-through-both-direct-and-indirect-activation-of-bkca-channels
#20
Tengteng Zhao, Huirong Zhang, Cheng Jin, Fang Qiu, Ying Wu, Lijun Shi
Melatonin, synthesized primarily by the pineal gland, is a neuroendocrine hormone with high membrane permeability. The vascular effects of melatonin, including vasoconstriction and vasodilation, have been demonstrated in numerous studies. However, the mechanisms underlying these effects are not fully understood. Large-conductance Ca2+-activated K+ (BKCa) channels are expressed broadly on smooth muscle cells and play an important role in vascular tone regulation. The present study explored the mechanisms of myocyte BKCa channels and endothelial factors underlying the action of melatonin on the mesenteric arteries (MAs)...
July 4, 2017: Journal of Molecular Endocrinology
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