Read by QxMD icon Read


Betty Titus Mathew, Shaima Raji, Sawsan Dagher, Ali Hilal-Alnaqbi, Abdel-Hamid Ismail Mourad, Sulaiman Al-Zuhair, Mahmoud Al Ahmad, Khaled Abbas El-Tarabily, Amr Amin
Background: Activated carbon (AC) is a common adsorbent that is used in both artificial and bioartificial liver devices. Methods: Three natural materials - date pits of Phoenix dactylifera (fruit), Simmondsia chinensis (jojoba) seeds, and Scenedesmus spp. (microalgae) - were used in the present investigation as precursors for the synthesis of AC using physical activation. The chemical structures and morphology of AC were analyzed. Then, AC's bilirubin adsorption capacity and its cytotoxicity on normal liver (THLE2) and liver cancer (HepG2) cells were characterized...
2018: International Journal of Nanomedicine
Andrea Darzi, Manale Harfouche, Thurayya Arayssi, Samar Alemadi, Khalid A Alnaqbi, Humeira Badsha, Farida Al Balushi, Bassel Elzorkany, Hussein Halabi, Mohammed Hamoudeh, Wissam Hazer, Basel Masri, Mohammed A Omair, Imad Uthman, Nelly Ziade, Jasvinder A Singh, Robin Christiansen, Peter Tugwell, Holger J Schünemann, Elie A Akl
No abstract text is available yet for this article.
October 26, 2017: Health and Quality of Life Outcomes
Ali Hilal-Alnaqbi, Anas Alazzam, Sawsan Dagher, Bobby Mathew
This article models a dielectrophoresis based approach for achieving 3D focusing, of micro-scale objects, in microfluidic devices. The microfluidic device employs four planar electrodes; two electrodes each on the top and bottom surface of the microchannel and each slightly protrude into the microchannel. Each electrode establishes electric field with the neighboring electrode on the same and opposite surfaces. The dielectrophoretic force pushes the micro-scale objects both the directions transverse to the flow direction to achieve the desired 3D focusing...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Andrea Darzi, Manale Harfouche, Thurayya Arayssi, Samar Alemadi, Khalid A Alnaqbi, Humeira Badsha, Farida Al Balushi, Bassel Elzorkany, Hussein Halabi, Mohammed Hamoudeh, Wissam Hazer, Basel Masri, Mohammed A Omair, Imad Uthman, Nelly Ziade, Jasvinder A Singh, Robin Christiansen, Peter Tugwell, Holger J Schünemann, Elie A Akl
BACKGROUND: It has been hypothesized that adaptation of health practice guidelines to the local setting is expected to improve their uptake and implementation while cutting on required resources. We recently adapted the published American College of Rheumatology (ACR) Rheumatoid Arthritis (RA) treatment guideline to the Eastern Mediterranean Region (EMR). The objective of this paper is to describe the process used for the adaptation of the 2015 ACR guideline on the treatment of RA for the EMR...
September 21, 2017: Health and Quality of Life Outcomes
Christopher-Philipp Nobis, Sven Otto, Tamara Grigorieva, Mohamed Alnaqbi, Matthias Troeltzsch, Jakob Schöpe, Stefan Wagenpfeil, Michael Ehrenfeld, Klaus-Dietrich Wolff, Marco Rainer Kesting
PURPOSE: Elective neck dissection (END) is a common primary treatment strategy for oral tongue squamous cell carcinoma (OTSCC), although uncertainty remains regarding the necessary extent of END for strictly unilateral early stage OTSCC. The authors evaluated two END variations, unilateral and bilateral, to determine the optimal extent. MATERIALS AND METHODS: A retrospective cohort study was performed on patient data from two departments of oral and maxillofacial surgery...
April 2017: Journal of Cranio-maxillo-facial Surgery
Razan Alkhatib, Ali Hilal-Alnaqbi, Mariam Naciri, Rasoul Al-Majmaie, Prashanth Saseedharan, Sherif M Karam, Mohamed Al-Rubeai
The lining epithelium of the stomach includes multipotent stem cells which undergo proliferation and migration-associated differentiation. These cells give rise to multiple cell lineages that produce mucus, acid, pepsinogen and various hormones/peptides. A 3D culture for stem cells would facilitate identification of the factors that control proliferation and/or differentiation programs. Here, we report on the use of disk-like ImmobaSil HD silicone-rubber matrix based microcarriers that are permeable to oxygen and reduce the creation of toxic environment within the center of the microcarrierd for culturing the mouse gastric stem (mGS) cells...
January 1, 2017: Frontiers in Bioscience (Scholar Edition)
Ali Hilal-AlNaqbi, Salah B Al-Omari, Mohamed Y E Selim
The gasification and combustion of dry tree leaves and the cogasification of dry tree leaves soaking crude glycerol were studied experimentally. An updraft fixed bed gasification and combustion system was built. The operation was conducted at different air to fuel ratios. Results show more stable combustion and more effective heat transfer to furnace walls for the cases when tree leaves flakes are mixed with 20 percent (on mass basis) of crude glycerol, as compared with the case when only dry tree leaves are used as fuel...
2016: BioMed Research International
Abdulbari Bener, Elnour Elnaeim Dafeeah, Khalid Alnaqbi
STUDY DESIGN: Cross-sectional. PURPOSE: The purpose of the study was to determine the prevalence of low back pain (LBP) in the primary care setting with emphasis on the socio-demographic contributing factors and impact of LBP on lifestyle habits. OVERVIEW OF LITERATURE: LBP is one of the most common medical conditions seen in the Primary Health Care Clinic. METHODS: A representative sample of 2,600 patients were approached and 1,829 subjects agreed to participate in this study (70...
June 2014: Asian Spine Journal
Dharini Mahendira, Arane Thavaneswaran, Adele Carty, Nigil Haroon, Ammepa Anton, Laura Passalent, Khalid A Alnaqbi, Laurie Savage, Elin Aslanyan, Robert D Inman
OBJECTIVE: There are unexplained sex-specific changes in the clinical expression of ankylosing spondylitis (AS). We sought to examine the potential effect of exogenous estrogen in the form of oral contraceptive pills (OCP) on AS initiation and severity. METHODS: This cross-sectional study consisted of women with AS from the membership of the Spondylitis Association of America. Measures of disease severity included use of biological agents and hip replacement surgery, while Bath AS Functional Index (BASFI) scores served as a surrogate marker of disability...
July 2014: Journal of Rheumatology
Mahmoud Al Ahmad, Sulaiman Al-Zuhair, Hanifa Taher, Ali Hilal-Alnaqbi
Most conventional techniques for the determination of microalgae lipid content are time consuming and in most cases are indirect and require excessive sample preparations. This work presents a new technique that utilizes radio frequency (RF) for rapid lipid quantification, without the need for sample preparation. Tests showed that a shift in the resonance frequency of a RF open-ended coaxial resonator and a gradual increase in its resonance magnitude may occur as the lipids content of microalgae cells increases...
2014: Scientific Reports
Ali Hilal-Alnaqbi, Abdel-Hamid I Mourad, Basem F Yousef
A mathematical model is developed to predict oxygen transfer in the fiber-in-fiber (FIF) bioartificial liver device. The model parameters are taken from the constructed and tested FIF modules. We extended the Krogh cylinder model by including one more zone for oxygen transfer. Cellular oxygen uptake was based on Michaelis-Menten kinetics. The effect of varying a number of important model parameters is investigated, including (1) oxygen partial pressure at the inlet, (2) the hydraulic permeability of compartment B (cell region), (3) the hydraulic permeability of the inner membrane, and (4) the oxygen diffusivity of the outer membrane...
May 2014: Biotechnology and Applied Biochemistry
Khalid A Alnaqbi, Zahi Touma, Laura Passalent, Sindhu R Johnson, George A Tomlinson, Adele Carty, Robert D Inman
OBJECTIVE: There is an unacceptable delay in the diagnosis of axial spondyloarthritis (axSpA) in its early stages among patients at high risk, in particular those with inflammatory bowel disease (IBD). Our objectives were to develop a sensible and reliable questionnaire to identify undetected axSpA among patients with IBD. METHODS: Literature was reviewed for item generation in the Toronto axSpA Questionnaire on IBD (TASQ-IBD). Sensibility of the questionnaire was assessed among healthcare professionals and patients...
October 2013: Journal of Rheumatology
Ali Hilal-Alnaqbi, Abdel-Hamid I Mourad, Basem F Yousef, John D S Gaylor
Bioartificial liver support provides a bridge to transplantation which is at present the only proven specific treatment for acute liver failure. In this paper, a novel multi-coaxial hollow fiber bioreactor so-called "Fibre-in-Fibre FIF Bioartificial liver device" with three compartments is experimentally and mathematically studied. The mathematical model in this paper is an extension of Krogh cylinder model for hollow fibre devices by including one more zone for oxygen transfer, i.e. oxygenation compartment...
2013: Bio-medical Materials and Engineering
Abdulbari Bener, Elnour E Dafeeah, Khalid Alnaqbi, Omar Falah, Taha Aljuhaisi, Alhassan Sadeeq, Shehryar Khan, Josia Schlogl
BACKGROUND: Low back pain is one of the most common conditions for which patients seek medical care. AIM: The aim of the study was to study the epidemiology of low back pain in primary care setting with emphasis on frequency, sociodemographic factors, and impact of low back pain on lifestyle habits. SUBJECTS AND METHODS: This is a cross-sectional study. A representative sample of 2742 patients was approached and 2180 subjects agreed to participate in this study (79...
July 1, 2013: Journal of Primary Care & Community Health
Ali Hilal-Alnaqbi, Alan Y C Hu, Zhibing Zhang, Mohamed Al-Rubeai
Chinese hamster ovary (CHO) cells producing β-galactosidase (β-gal) were successfully cultured on silicone-based porous microcarriers (ImmobaSil FS) in a 1 L stirred-tank perfusion bioreactor. We studied the growth, metabolism, and productivity of free and immobilized cells to understand cellular activity in immobilized conditions. CHO cells attached to ImmobaSil FS significantly better than to other microcarriers. Scanning electron microscope images showed that the CHO cells thoroughly colonized the porous surfaces of the ImmobaSil FS, exhibiting a spherical morphology with microvilli that extended to anchorage cells on the silicone surface...
July 2013: Biotechnology and Applied Biochemistry
Mohammed A Omair, Khalid A Alnaqbi, Peter Lee
Tumor necrosis factor inhibitors (TNFI) are novel therapies used to treat ankylosing spondylitis (AS). Demyelinating disease is a rare but serious complication of TNFI. We report a patient with a case of AS who developed demyelinating disease secondary to TNFI and was treated successfully with rituximab.
August 2012: Clinical Rheumatology
K A Y Alnaqbi, S Joshi, S Ghazal-Aswad, F M Abu Zidan
Primary umbilical tumours are extremely rare. We report primary serous adenocarcinoma arising from the coelomic mesothelium of the hernial sac. A 60-year-old woman presented with an umbilical swelling of six months duration that became painful in the last three days. Examination revealed a tender umbilical swelling diagnosed as obstructive hernia that needed surgery. When dissecting the sac during surgery, a small subcutaneous abscess was encountered. The sac contained an omentum with a hard nodule at the surface which was excised...
December 2007: Singapore Medical Journal
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"