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https://www.readbyqxmd.com/read/28338726/cumulative-exposure-to-systolic-blood-pressure-during-young-adulthood-through-midlife-and-the-urine-albumin-to-creatinine-ratio-at-midlife
#1
Holly Kramer, Laura Colangelo, Cora E Lewis, David R Jacobs, Mark Pletcher, Kirstin Bibbins-Domingo, Alex Chang, David Siscovick, Michael Shlipak, Carmen A Peralta, Nisha Bansal, Paul Muntner, Kiang Liu
BACKGROUND: Higher blood pressure during young adulthood may increase cardiovascular and kidney disease risk later in life. This study examined the association of cumulative systolic blood pressure (SBP) exposure during young adulthood through midlife with urine albumin-to-creatinine ratios (ACR) measured during midlife. METHODS: We used data from the Coronary Artery Risk Development in Young Adults (CARDIA) study, a biracial cohort recruited in 4 urban areas during years 1985-1986...
February 21, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28332920/terminal-decline-of-episodic-memory-and-perceptual-speed-in-a-biracial-population
#2
Robert S Wilson, Kumar B Rajan, Lisa L Barnes, Willemijn Jansen, Priscilla Amofa, Jennifer Weuve, Denis A Evans
We compared trajectories of terminal cognitive decline in older Black (n = 3372) and White (n = 1756) persons from a defined population who completed tests of episodic memory and perceptual speed at 3-year intervals for up to 18 years. During a mean of 9.9 years of observation, 1608 Black persons and 902 White persons died. Preterminal decline of episodic memory did not differ by race. Terminal episodic memory decline began earlier in Black persons (mean of 4.3 years before death) than in White persons (mean = 3...
March 23, 2017: Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition
https://www.readbyqxmd.com/read/28321981/evaluation-of-the-modified-findrisc-diabetes-score-to-identify-individuals-at-high-risk-for-diabetes-among-middle-aged-white-and-black-aric-study-participants
#3
Manjusha Kulkarni, Randi E Foraker, Ann Marie McNeill, Cynthia Girman, Sherita Hill Golden, Wayne D Rosamond, Bruce Duncan, Maria Ines Schmidt, Jaakko Tuomilehto
OBJECTIVE: To evaluate a modified Finnish Diabetes Risk Score (FINDRISC) score for predicting the risk of incident diabetes among white and black middle-aged Atherosclerosis Risk in Communities (ARIC) study participants. Research Design and Methods We assessed 9,754 ARIC cohort participants who were free of diabetes at baseline. Logistic regression and receiver operator characteristic (ROC) curves were used to evaluate a modified FINDRISC score for predicting incident diabetes after 9 years of follow-up, overall and by race/gender group...
March 21, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28258258/association-between-acute-kidney-disease-and-intravenous-dye-administration-in-patients-with-acute-stroke-a-population-based-study
#4
Stacie L Demel, Aaron W Grossman, Jane C Khoury, Charles J Moomaw, Kathleen Alwell, Brett M Kissela, Daniel Woo, Matthew L Flaherty, Simona Ferioli, Jason Mackey, Felipe De Los Rios la Rosa, Sharyl Martini, Opeolu Adeoye, Dawn O Kleindorfer
BACKGROUND AND PURPOSE: Computed tomographic angiography and conventional angiography provide timely vascular anatomic information in patients with stroke. However, iodinated contrast dye may cause acute kidney injury (AKI). Within a large, biracial population, we examined in-hospital incidence of new or worsening kidney disease in patients with stroke and its association with administration of intravenous dye. METHODS: All adult residents of the Greater Cincinnati/Northern Kentucky region with acute ischemic stroke or intracerebral hemorrhage who presented to an emergency department in 2010 were included...
March 3, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28235961/distributions-of-subclinical-cardiovascular-disease-in-a-socioeconomically-and-racially-diverse-sample
#5
Carrington R Wendell, Shari R Waldstein, Michele K Evans, Alan B Zonderman
BACKGROUND AND PURPOSE: Differential subgroup vulnerability to subclinical cardiovascular disease is likely, and yet few, if any, studies have addressed interactive relations of age, sex, race, and socioeconomic status (SES) to these conditions to examine nuances of known health disparities. We examined distributions of carotid atherosclerosis and arterial stiffness in a socioeconomically diverse, biracial, urban sample. METHODS: Participants (n=2270) in the population-based HANDLS study (Healthy Aging in Neighborhoods of Diversity Across the Life Span; 30-64 years old, 44% men, 57% African American, 39% with household income <125% federal poverty threshold) underwent carotid intimal medial thickness (IMT) and pulse wave velocity assessment...
February 24, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28191321/postprandial-lipemia-and-the-risk-of-coronary-heart-disease-and-stroke-the-atherosclerosis-risk-in-communities-aric-study
#6
Dmitry Kats, A Richey Sharrett, Henry N Ginsberg, Vijay Nambi, Christie M Ballantyne, Ron C Hoogeveen, Gerardo Heiss
OBJECTIVE: Excessive levels of triglyceride-rich lipoproteins during postprandial lipemia (PPL) have been reported to be atherogenic. However, it is unclear whether the degree of PPL independently predicts cardiovascular disease (CVD) given the scarcity of longitudinal data with standardised measures of postprandial change. We reexamined associations of PPL with incident CVD events in a population-based cohort using detailed measures of postprandial change from a standardised fat challenge...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28179490/paleolithic-and-mediterranean-diet-pattern-scores-are-inversely-associated-with-all-cause-and-cause-specific-mortality-in-adults
#7
Kristine A Whalen, Suzanne Judd, Marjorie L McCullough, W Dana Flanders, Terryl J Hartman, Roberd M Bostick
Background: Poor diet quality is associated with a higher risk of many chronic diseases that are among the leading causes of death in the United States. It has been hypothesized that evolutionary discordance may account for some of the higher incidence and mortality from these diseases.Objective: We investigated associations of 2 diet pattern scores, the Paleolithic and the Mediterranean, with all-cause and cause-specific mortality in the REGARDS (REasons for Geographic and Racial Differences in Stroke) study, a longitudinal cohort of black and white men and women ≥45 y of age...
February 8, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28127708/associations-between-hunter-type-a-b-personality-and-cardiovascular-risk-factors-from-adolescence-through-young-adulthood
#8
Benjamin D Pollock, Wei Chen, Emily W Harville, Lydia A Bazzano
PURPOSE: Type A personality, characterized by action-oriented tendencies, has been linked to cardiovascular disease in middle-aged and elderly adults. Alternatively, limited research has tested whether personality type A/B and cardiovascular (CVD) risk are linked prior to adulthood. Therefore, we used the Hunter-Wolf A/B personality score to determine whether personality type A/B is associated with traditional CVD risk factors during adolescence, and more importantly if personality type, or its individual type A components, are associated with cardiovascular risk through young adulthood...
January 26, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28065769/habitual-and-recent-sleep-durations-graded-and-interactive-risk-for-impaired-glycemic-control-in-a-biracial-population
#9
Donald L Bliwise, Sophia A Greer, Michael K Scullin, Lawrence S Phillips
BACKGROUND: We examined how habitual sleep duration interacts with recent sleep (2 nights) to predict morning oral glucose tolerance test results. We hypothesized that short habitual and recent sleep durations would be additive for poor glucose control. METHODS: A biracial population of adults (n = 1559) without known diabetes and recruited from the workforce of 2 urban universities was assessed for glycated hemoglobin and underwent oral glucose tolerance testing...
January 5, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28061370/fine-particulate-air-pollution-and-premature-ventricular-contractions-the-reasons-for-geographic-and-racial-differences-in-stroke-regards-study
#10
Wesley T O'Neal, Elsayed Z Soliman, Jimmy T Efird, Virginia J Howard, George Howard, Leslie A McClure
BACKGROUND: It is unknown if higher levels of ambient particulate matter (PM) exposure increase the risk for premature ventricular contractions (PVC) in a population-based study of men and women, and if this relationship varies by race or sex. METHODS: We examined the association of PM <2.5µm in diameter (PM2.5) concentration with PVCs in 26,121 (mean age=64±9.3 years; 55% female; 41% black) participants from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study...
April 2017: Environmental Research
https://www.readbyqxmd.com/read/28043942/a-cognitive-turning-point-in-development-of-clinical-alzheimer-s-disease-dementia-and-mild-cognitive-impairment-a-biracial-population-study
#11
Kumar B Rajan, Robert S Wilson, Lisa L Barnes, Neelum T Aggarwal, Jennifer Weuve, Denis A Evans
BACKGROUND: Cognitive changes during the preclinical phase of Alzheimer's disease (AD) dementia have been characterized among European Americans (EAs), but studies of preclinical changes among African Americans (AAs) are notably absent. METHODS: Preclinical changes in cognition before the development of AD dementia and mild cognitive impairment over a period of 18 years were examined using change points in a biracial sample of 2,125 older adults. RESULTS: Of 2,125 participants, 442 (21%) developed AD dementia and 661 (31%) developed mild cognitive impairment...
January 1, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28039314/olfaction-and-risk-of-dementia-in-a-biracial-cohort-of-older-adults
#12
Kristine Yaffe, Daniel Freimer, Honglei Chen, Keiko Asao, Andrea Rosso, Susan Rubin, Greg Tranah, Steve Cummings, Eleanor Simonsick
OBJECTIVE: Prior studies indicate that olfactory function may be an early marker for cognitive impairment, but the body of evidence has been largely restricted to white populations. METHODS: We studied 2,428 community-dwelling black and white older adults (baseline age 70-79 years) without dementia enrolled in the Health, Aging, and Body Composition (Health ABC) study. Olfaction was measured as odor identification (OI) with the 12-item Cross Cultural Smell Identification Test in year 3...
January 31, 2017: Neurology
https://www.readbyqxmd.com/read/27994005/associations-of-brain-structure-with-adiposity-and-changes-in-adiposity-in-a-middle-aged-and-older-biracial-population
#13
B Gwen Windham, Seth T Lirette, Myriam Fornage, Emelia J Benjamin, Kirby G Parker, Stephen T Turner, Clifford R Jack, Michael E Griswold, Thomas H Mosley
BACKGROUND: Studies of adiposity and brain pathology in African Americans (AA) are sparse despite higher rates of obesity, dementia, and dementia-associated brain pathology in AA. This study examined relations of adiposity to white matter hyperintensities (WMH) and total brain volume (TBV) in AA and non-Hispanic whites (NHW). METHODS: Waist circumference (WC) and body mass index (BMI) were measured in the Genetic Epidemiology Network of Arteriopathy study at Visits 1 (mean age 57 [±11]) and 2 (mean age 61 [±10], mean 5...
December 18, 2016: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/27902495/methodological-evaluation-of-the-noninvasive-estimation-of-central-systolic-blood-pressure-in-nontreated-patients-the-bogalusa-heart-study
#14
COMPARATIVE STUDY
Camilo Fernandez, Robert Hsu, Gary Sander, Azad Hussain, Rupert Barshop, Shengxu Li, Tian Shu, Tao Zhang, Patrycja Galazka, Wei Chen, Lydia Bazzano, Thomas D Giles
OBJECTIVES: This study sought to compare the estimation of central systolic blood pressure (cSBP) obtained by two different noninvasive devices, in addition to its comparisons with measured peripheral systolic blood pressure (pSBP), in a biracial (Black/White) community-based cohort. PARTICIPANTS AND METHODS: Estimations of cSBP by applanation tonometry were obtained in 586 participants of the Bogalusa Heart Study (mean age: 43.5 years; 69% White, 54% women) using two different commonly used instruments: Omron HEM-9000AI and SphygmoCor CPV...
April 2017: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/27895486/factors-associated-with-vitamin-d-status-of-low-income-hospitalized-psychiatric-patients-results-of-a-retrospective-study
#15
Alessandra N Bazzano, Lisa Littrell, Stephen Lambert, Cody Roi
BACKGROUND: Recent evidence has indicated a potential role of vitamin D3 in a range of neuropsychiatric outcomes, as well as on cognitive function, but conflicting data have left that role uncertain. Understanding potential associations of vitamin D status with psychiatric illness will allow clinicians to better assess therapeutic options. Few studies have examined vitamin D status among a racially diverse group of psychiatric patients who have been hospitalized, and none has done so in the southern US where socioeconomic inequality is high...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27852134/further-evidence-of-the-limited-role-of-candidate-genes-in-relation-to-infant-mother-attachment-outcomes
#16
Esther M Leerkes, Lindsey R Gedaly, Nan Zhou, Susan Calkins, Vincent C Henrich, Andrew Smolen
In this paper, we examine the associations between specific candidate genes (DRD2, DRD4, COMT, biallelic and tri-allelic 5HTTLPR, and OXTR) and infant attachment outcomes as main effects and in conjunction with maternal sensitivity. The sample included 200 infants (97 European American, 94 African-American, and 9 biracial) and their mothers. Maternal sensitivity and overtly negative maternal behavior were observed when infants were 6 months and 1 year old in distress-eliciting contexts, attachment was assessed via the Strange Situation at age 1, and DNA samples were collected when children were 2 years old...
February 2017: Attachment & Human Development
https://www.readbyqxmd.com/read/27822934/births-to-parents-with-asian-origins-in-the-united-states-1992-2012
#17
Do Hyun Kim, Jihyun Jeon, Chang Gi Park, Sudhir Sriram, Kwang Sun Lee
Despite a remarkable increase in Asian births in the U.S., studies on their birth outcomes have been lacking. We investigated outcomes of births to Asian parents and biracial Asian/White parents in the U.S. From the U.S. birth data (1992-2012), we selected singleton births to Korean, Chinese, Japanese, Filipino, Asian Indian, and Vietnamese. These births were divided into three groups; births to White mother/Asian father, Asian mother/White father, and births to the both ethnic Asian parents. We compared birth outcomes of these 18 subgroups to those of the White mother/White father group...
December 2016: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27792658/microbiota-dependent-metabolite-trimethylamine-n-oxide-and-coronary-artery-calcium-in-the-coronary-artery-risk-development-in-young-adults-study-cardia
#18
Katie A Meyer, Thomas Z Benton, Brian J Bennett, David R Jacobs, Donald M Lloyd-Jones, Myron D Gross, J Jeffrey Carr, Penny Gordon-Larsen, Steven H Zeisel
BACKGROUND: Clinical studies implicate trimethylamine N-oxide (TMAO; a gut microbiota-dependent nutrient metabolite) in cardiovascular disease risk. There is a lack of population-based data on the role of TMAO in advancing early atherosclerotic disease. We tested the prospective associations between TMAO and coronary artery calcium (CAC) and carotid intima-media thickness (cIMT). METHODS AND RESULTS: Data were from the Coronary Artery Risk Development in Young Adults Study (CARDIA), a biracial cohort of US adults recruited in 1985-1986 (n=5115)...
October 21, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27639985/psychological-contributors-to-noncompletion-of-an-adolescent-preoperative-bariatric-surgery-program
#19
Megan J Cohen, Jennifer L Curran, Thao-Ly T Phan, Kirk Reichard, George A Datto
BACKGROUND: Noncompletion of preoperative bariatric programs is a significant problem among adolescents. Adult studies suggest that psychological factors contribute to noncompletion of preoperative bariatric programs. OBJECTIVE: The aim of this study was to determine the association between adolescent psychological functioning and completion of the preoperative phase of a bariatric program. SETTING: The study was conducted at a tertiary care children's hospital affiliated with a university medical center...
January 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/27610927/sleep-architecture-relates-to-daytime-affect-and-somatic-complaints-in-clinically-anxious-but-not-healthy-children
#20
Cara A Palmer, Candice A Alfano
It is increasingly clear that seminal sleep-affective relationships begin to take root in childhood, yet studies exploring how nighttime sleep characteristics relate to daytime affective symptoms, both in clinical and healthy populations of children, are lacking. The current study sought to explore these relationships by investigating whether trait-like and/or daily reports of affective and somatic symptoms of children with generalized anxiety disorder and matched controls relate to sleep architecture. Sixty-six children (ages 7-11; 54...
March 2017: Journal of Clinical Child and Adolescent Psychology
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