Junqiang Hu, Gang Wang, Mingxuan Hou, Shilong Du, Jun Han, Yangguang Yu, Hongxia Gao, Dan He, Jianrong Shi, Yin-Won Lee, Sherif Ramzy Mohamed, Dawood H Dawood, Qing Hong, Xin Liu, Jianhong Xu
Zearalenone (ZEN) is an estrogenic mycotoxin most frequently found in cereals that can cause reproductive disorders in livestock and pose a severe threat to animal husbandry. In this study, we isolated a ZEN-degrading Aeromicrobium strain from soil and found that ZenH, a hydrolase, is responsible for the hydrolysis of ZEN through comparative proteomics and biochemical studies. ZenH exhibited the highest similarity with lactone hydrolase ZHD607 from Phialophora americana at 21.52%. ZenH displayed maximal enzymatic activity at pH 7...
February 8, 2023: Journal of Agricultural and Food Chemistry