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maned wolf

L Mark Elbroch, Anna Kusler
Background: Interspecific competition affects species fitness, community assemblages and structure, and the geographic distributions of species. Established dominance hierarchies among species mitigate the need for fighting and contribute to the realized niche for subordinate species. This is especially important for apex predators, many of which simultaneous contend with the costs of competition with more dominant species and the costs associated with human hunting and lethal management...
2018: PeerJ
R C Siqueira, S C Rahal, L R Inamassu, M J Mamprim, M Felix, M S Castilho, L R Mesquita, V L Ribeiro, C R Teixeira, F B Rassy
This study describes the osteology and radiology of the pelvic limb in maned wolves. Ten (five live and five dead) maned wolves (Chrysocyon brachyurus), five males and five females, aged from 2 to 7 years old were used. Digital radiographs were taken and recorded for both pelvic limbs in all animals. Osteology was correlated with the radiographic images. The pelvis had a rectangular shape, and the obturator foramen (foramen obturatum) was oval. The femoral neck (collum femoris) was short and thick. The greater trochanter (trochanter major) extended proximally to near the dorsum of the femoral head (caput ossis femoris)...
September 20, 2017: Anatomia, Histologia, Embryologia
Daniela A Braun, Jia Rao, Geraldine Mollet, David Schapiro, Marie-Claire Daugeron, Weizhen Tan, Olivier Gribouval, Olivia Boyer, Patrick Revy, Tilman Jobst-Schwan, Johanna Magdalena Schmidt, Jennifer A Lawson, Denny Schanze, Shazia Ashraf, Jeremy F P Ullmann, Charlotte A Hoogstraten, Nathalie Boddaert, Bruno Collinet, Gaëlle Martin, Dominique Liger, Svjetlana Lovric, Monica Furlano, I Chiara Guerrera, Oraly Sanchez-Ferras, Jennifer F Hu, Anne-Claire Boschat, Sylvia Sanquer, Björn Menten, Sarah Vergult, Nina De Rocker, Merlin Airik, Tobias Hermle, Shirlee Shril, Eugen Widmeier, Heon Yung Gee, Won-Il Choi, Carolin E Sadowski, Werner L Pabst, Jillian K Warejko, Ankana Daga, Tamara Basta, Verena Matejas, Karin Scharmann, Sandra D Kienast, Babak Behnam, Brendan Beeson, Amber Begtrup, Malcolm Bruce, Gaik-Siew Ch'ng, Shuan-Pei Lin, Jui-Hsing Chang, Chao-Huei Chen, Megan T Cho, Patrick M Gaffney, Patrick E Gipson, Chyong-Hsin Hsu, Jameela A Kari, Yu-Yuan Ke, Cathy Kiraly-Borri, Wai-Ming Lai, Emmanuelle Lemyre, Rebecca Okashah Littlejohn, Amira Masri, Mastaneh Moghtaderi, Kazuyuki Nakamura, Fatih Ozaltin, Marleen Praet, Chitra Prasad, Agnieszka Prytula, Elizabeth R Roeder, Patrick Rump, Rhonda E Schnur, Takashi Shiihara, Manish D Sinha, Neveen A Soliman, Kenza Soulami, David A Sweetser, Wen-Hui Tsai, Jeng-Daw Tsai, Rezan Topaloglu, Udo Vester, David H Viskochil, Nithiwat Vatanavicharn, Jessica L Waxler, Klaas J Wierenga, Matthias T F Wolf, Sik-Nin Wong, Sebastian A Leidel, Gessica Truglio, Peter C Dedon, Annapurna Poduri, Shrikant Mane, Richard P Lifton, Maxime Bouchard, Peter Kannu, David Chitayat, Daniella Magen, Bert Callewaert, Herman van Tilbeurgh, Martin Zenker, Corinne Antignac, Friedhelm Hildebrandt
Galloway-Mowat syndrome (GAMOS) is an autosomal-recessive disease characterized by the combination of early-onset nephrotic syndrome (SRNS) and microcephaly with brain anomalies. Here we identified recessive mutations in OSGEP, TP53RK, TPRKB, and LAGE3, genes encoding the four subunits of the KEOPS complex, in 37 individuals from 32 families with GAMOS. CRISPR-Cas9 knockout in zebrafish and mice recapitulated the human phenotype of primary microcephaly and resulted in early lethality. Knockdown of OSGEP, TP53RK, or TPRKB inhibited cell proliferation, which human mutations did not rescue...
October 2017: Nature Genetics
Jenna D Hinton, Luis R Padilla, Priscilla H Joyner, Rodney Schnellbacher, Timothy F Walsh, Copper Aitken-Palmer
Gastric dilatation volvulus (GDV) was identified in six adult maned wolves ( Chrysocyon brachyurus ) housed at the Smithsonian Conservation Biology Institute in Front Royal, Virginia, and the Dickerson Park Zoo in Springfield, Missouri. Four individuals were found dead in their enclosures, and GDV was diagnosed postmortem based on radiographic and necropsy findings. Two individuals were diagnosed with GDV antemortem, with one wolf surviving following surgical intervention and supportive management. A concurrent splenic torsion was identified in three of six cases...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
Bozho Todorich, Aristomenis Thanos, Yoshihiro Yonekawa, Gerta Mane, Madeleine Hasbrook, Benjamin J Thomas, Maria A Woodward, George A Williams, Antonio Capone, Jeremy D Wolfe, Lisa J Faia, Tarek S Hassan
PURPOSE: To evaluate the efficacy of a dexamethasone intravitreal implant in combination with intravitreal anti-VEGF agents for treatment resistant neovascular age-related macular degeneration (nvAMD). METHODS: This study was designed as a single-center, retrospective interventional case series. Consecutive patients with treatment-resistant nvAMD underwent simultaneous combined injection of anti-VEGF agent and dexamethasone intravitreal implant. Eighteen patients with mean age of 81...
2017: Journal of Vitreoretinal Diseases
Shuai Shang, Xiaoyang Wu, Jun Chen, Huanxin Zhang, Huaming Zhong, Qinguo Wei, Jiakuo Yan, Haotian Li, Guangshuai Liu, Weilai Sha, Honghai Zhang
Bitter taste receptors (Tas2rs) play important roles in mammalian defense mechanisms by helping animals detect and avoid toxins in food. Although Tas2r genes have been widely studied in several mammals, minimal research has been performed in canids. To analyze the genetic basis of Tas2r genes in canids, we first identified Tas2r genes in the wolf, maned wolf, red fox, corsac fox, Tibetan fox, fennec fox, dhole and African hunting dog. A total of 183 Tas2r genes, consisting of 118 intact genes, 6 partial genes and 59 pseudogenes, were detected...
July 2017: Amino Acids
Copper Aitken-Palmer, Dipl A C Z M, Lisa H Ware, Lacey Braun, Kenneth Lang, Priscilla H Joyner
Maned wolves ( Chrysocyon brachyurus ) maintained in ex situ populations challenge veterinarians and managers with high neonatal mortality and parental incompetence. These challenges led to the development of a novel diagnostic approach for pregnancy detection using radiographic imaging without anesthesia or sedation. To do this, a specialized crate was constructed to easily contain a single maned wolf, allowing the capture of lateral projection radiographic images of the abdomen prior to and throughout a 66-day pregnancy (days 20, 34, 48, and 55 of 66)...
March 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
Julia Angélica Gonçalves Silveira, Mirella Lauria D'Elia, Isabela de Oliveira Avelar, Lara Ribeiro de Almeida, Hudson Andrade Dos Santos, Danielle Ferreira de Magalhães Soares, Múcio Flávio Barbosa Ribeiro, Walter Dos Santos Lima, Roselene Ecco
An adult free-ranged female maned wolf was rescued from a periurban area subject to anthropogenic disturbances in the Minas Gerais, Brazil. The animal presented poor body condition and anemia. The clinical condition rapidly deteriorated culminating in dead and a necropsy was performed. The main gross lesions were marked anemia and blood content in the intestines accompanied by many types of parasites. The protozoa Rangelia vitalii was identified by histopathological analysis predominantly within the cytoplasm of endothelial cells of capillaries of the small intestine...
December 2016: International Journal for Parasitology. Parasites and Wildlife
Mariana Malzoni Furtado, Erika Midori Kida Hayashi, Susan Dora Allendorf, Claudio José Coelho, Anah Tereza de Almeida Jácomo, Jane Megid, José Domingues Ramos Filho, Leandro Silveira, Natália Mundim Tôrres, José Soares Ferreira Neto
Human population growth around protected areas increases the contact between wild and domestic animals, promoting disease transmission between them. This study investigates the exposure of free-ranging wild carnivores and domestic dogs to canine distemper virus (CDV) and parvovirus in Emas National Park (ENP) in the Cerrado savanna of central Brazil. Serum samples were collected from 169 wild carnivores, including the maned wolf (Chrysocyon brachyurus), crab-eating fox (Cerdocyon thous), hoary fox (Pseudalopex vetulus), puma (Puma concolor), ocelot (Leopardus pardalis), pampas cat (Leopardus colocolo), jaguarundi (Herpailurus yagouaroundi), striped hog-nosed skunk (Conepatus semistriatus) and coati (Nasua nasua), and from 35 domestic dogs living on rural properties bordering ENP...
September 2016: EcoHealth
Marianna Madeo, Michelle Stewart, Yuyang Sun, Nadia Sahir, Sarah Wiethoff, Indra Chandrasekar, Anna Yarrow, Jill A Rosenfeld, Yaping Yang, Dawn Cordeiro, Elizabeth M McCormick, Colleen C Muraresku, Tyler N Jepperson, Lauren J McBeth, Mohammed Zain Seidahmed, Heba Y El Khashab, Muddathir Hamad, Hamid Azzedine, Karl Clark, Silvia Corrochano, Sara Wells, Mariet W Elting, Marjan M Weiss, Sabrina Burn, Angela Myers, Megan Landsverk, Patricia L Crotwell, Quinten Waisfisz, Nicole I Wolf, Patrick M Nolan, Sergio Padilla-Lopez, Henry Houlden, Richard Lifton, Shrikant Mane, Brij B Singh, Marni J Falk, Saadet Mercimek-Mahmutoglu, Kaya Bilguvar, Mustafa A Salih, Abraham Acevedo-Arozena, Michael C Kruer
Glutamatergic neurotransmission governs excitatory signaling in the mammalian brain, and abnormalities of glutamate signaling have been shown to contribute to both epilepsy and hyperkinetic movement disorders. The etiology of many severe childhood movement disorders and epilepsies remains uncharacterized. We describe a neurological disorder with epilepsy and prominent choreoathetosis caused by biallelic pathogenic variants in FRRS1L, which encodes an AMPA receptor outer-core protein. Loss of FRRS1L function attenuates AMPA-mediated currents, implicating chronic abnormalities of glutamatergic neurotransmission in this monogenic neurological disease of childhood...
June 2, 2016: American Journal of Human Genetics
Jamile de Moura Bubadué, Nilton Cáceres, Renan Dos Santos Carvalho, Carlo Meloro
Species morphological changes can be mutually influenced by environmental or biotic factors, such as competition. South American canids represent a quite recent radiation of taxa that evolved forms very disparate in phenotype, ecology and behaviour. Today, in the central part of South America there is one dominant large species (the maned wolf, Chrysocyon brachyurus) that directly influence sympatric smaller taxa via interspecific killing. Further south, three species of similar sized foxes (Lycalopex spp.) share the same habitats...
2016: Evolutionary Biology
Carlyle Mendes Coelho, Cristiano Schetini de Azevedo, Marcelo Alcino de Barros Vaz Guimarães, Robert John Young
Environmental enrichment is a technique that may reduce the stress of nonhuman animals in captivity. Stress may interfere with normal behavioral expression and affect cognitive decision making. Noninvasive hormonal studies can provide important information about the stress statuses of animals. This study evaluated the effectiveness of different environmental enrichment treatments in the diminution of fecal glucocorticoid metabolites (stress indicators) of three captive maned wolves (Chrysocyon brachyurus). Correlations of the fecal glucocorticoid metabolite levels with expressed behaviors were also determined...
October 2016: Journal of Applied Animal Welfare Science: JAAWS
Paulo de Souza Junior, Flavio Machado de Moraes, Natan da Cruz de Carvalho, Evandro Alves Canelo, Roberto Thiesen, André Luiz Quagliatto Santos
Chrysocyon brachyurus (maned wolf) is the biggest South American canid and has a high frequency of dental injuries, both in the wild and in captivity. Thus, veterinary procedures are necessary to preserve the feeding capacity of hundreds of captive specimens worldwide. The aim of this study was to investigate the mandibular morphometry of the maned wolf with emphasis on the establishment of anatomic references for anesthetic block of the inferior alveolar and mental nerves. Therefore, 16 measurements in 22 mandibles of C...
March 2016: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
Richard R Orlandi, Todd T Kingdom, Peter H Hwang, Timothy L Smith, Jeremiah A Alt, Fuad M Baroody, Pete S Batra, Manuel Bernal-Sprekelsen, Neil Bhattacharyya, Rakesh K Chandra, Alexander Chiu, Martin J Citardi, Noam A Cohen, John DelGaudio, Martin Desrosiers, Hun-Jong Dhong, Richard Douglas, Berrylin Ferguson, Wytske J Fokkens, Christos Georgalas, Andrew Goldberg, Jan Gosepath, Daniel L Hamilos, Joseph K Han, Richard Harvey, Peter Hellings, Claire Hopkins, Roger Jankowski, Amin R Javer, Robert Kern, Stilianos Kountakis, Marek L Kowalski, Andrew Lane, Donald C Lanza, Richard Lebowitz, Heung-Man Lee, Sandra Y Lin, Valerie Lund, Amber Luong, Wolf Mann, Bradley F Marple, Kevin C McMains, Ralph Metson, Robert Naclerio, Jayakar V Nayak, Nobuyoshi Otori, James N Palmer, Sanjay R Parikh, Desiderio Passali, Anju Peters, Jay Piccirillo, David M Poetker, Alkis J Psaltis, Hassan H Ramadan, Vijay R Ramakrishnan, Herbert Riechelmann, Hwan-Jung Roh, Luke Rudmik, Raymond Sacks, Rodney J Schlosser, Brent A Senior, Raj Sindwani, James A Stankiewicz, Michael Stewart, Bruce K Tan, Elina Toskala, Richard Voegels, De Yun Wang, Erik K Weitzel, Sarah Wise, Bradford A Woodworth, Peter-John Wormald, Erin D Wright, Bing Zhou, David W Kennedy
BACKGROUND: The body of knowledge regarding rhinosinusitis(RS) continues to expand, with rapid growth in number of publications, yet substantial variability in the quality of those presentations. In an effort to both consolidate and critically appraise this information, rhinologic experts from around the world have produced the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS). METHODS: Evidence-based reviews with recommendations(EBRRs) were developed for scores of topics, using previously reported methodology...
February 2016: International Forum of Allergy & Rhinology
Jonathan D W Evans, Barbara Girerd, David Montani, Xiao-Jian Wang, Nazzareno Galiè, Eric D Austin, Greg Elliott, Koichiro Asano, Ekkehard Grünig, Yi Yan, Zhi-Cheng Jing, Alessandra Manes, Massimiliano Palazzini, Lisa A Wheeler, Ikue Nakayama, Toru Satoh, Christina Eichstaedt, Katrin Hinderhofer, Matthias Wolf, Erika B Rosenzweig, Wendy K Chung, Florent Soubrier, Gérald Simonneau, Olivier Sitbon, Stefan Gräf, Stephen Kaptoge, Emanuele Di Angelantonio, Marc Humbert, Nicholas W Morrell
BACKGROUND: Mutations in the gene encoding the bone morphogenetic protein receptor type II (BMPR2) are the commonest genetic cause of pulmonary arterial hypertension (PAH). However, the effect of BMPR2 mutations on clinical phenotype and outcomes remains uncertain. METHODS: We analysed individual participant data of 1550 patients with idiopathic, heritable, and anorexigen-associated PAH from eight cohorts that had been systematically tested for BMPR2 mutations. The primary outcome was the composite of death or lung transplantation...
February 2016: Lancet Respiratory Medicine
Susana González, Mariana Cosse, María del Rosario Franco, Louise Emmons, Carly Vynne, José Maurício Barbanti Duarte, Marcelo D Beccacesi, Jesús E Maldonado
The maned wolf (Chrysocyon brachyurus) is one of the largest South American canids, and conservation across this charismatic carnivore's large range is presently hampered by a lack of knowledge about possible natural subdivisions which could influence the population's viability. To elucidate the phylogeographic patterns and demographic history of the species, we used 2 mtDNA markers (D-loop and cytochrome b) from 87 individuals collected throughout their range, in Argentina, Bolivia, Brazil, and Uruguay. We found moderate levels of haplotype and nucleotide diversity, and the 14 D-loop haplotypes were closely related...
2015: Journal of Heredity
S N Vitaliano, H S Soares, A H H Minervino, A L Q Santos, K Werther, M F V Marvulo, D B Siqueira, H F J Pena, R M Soares, C Su, S M Gennari
This study aimed to isolate and genotype T. gondii from Brazilian wildlife. For this purpose, 226 samples were submitted to mice bioassay and screened by PCR based on 18S rRNA sequences. A total of 15 T. gondii isolates were obtained, including samples from four armadillos (three Dasypus novemcinctus, one Euphractus sexcinctus), three collared anteaters (Tamandua tetradactyla), three whited-lipped peccaries (Tayassu pecari), one spotted paca (Cuniculus paca), one oncilla (Leopardus tigrinus), one hoary fox (Pseudalopex vetulus), one lineated woodpecker (Dryocopus lineatus) and one maned wolf (Chrysocyon brachyurus)...
December 2014: International Journal for Parasitology. Parasites and Wildlife
Rodrigo Otávio Silveira Silva, Mirella Lauria D'Elia, Erika Procópio Tostes Teixeira, Pedro Lúcio Lithg Pereira, Danielle Ferreira de Magalhães Soares, Álvaro Roberto Cavalcanti, Aleksander Kocuvan, Maja Rupnik, André Luiz Quagliatto Santos, Carlos Augusto Oliveira Junior, Francisco Carlos Faria Lobato
Despite some case reports, the importance of Clostridium perfringens and Clostridium difficile for wild carnivores remains unclear. Thus, the objective of this study was to identify C. perfringens and C. difficile strains in stool samples from wild carnivore species in Brazil. A total of 34 stool samples were collected and subjected to C. perfringens and C. difficile isolation. Suggestive colonies of C. perfringens were then analyzed for genes encoding the major C. perfringens toxins (alpha, beta, epsilon and iota) and the beta-2 toxin (cpb2), enterotoxin (cpe) and NetB (netb) genes...
August 2014: Anaerobe
Amy E M Johnson, Elizabeth W Freeman, Mark Colgin, Caitlin McDonough, Nucharin Songsasen
Assisted reproductive techniques, such as ovarian manipulation and artificial insemination, are useful for enhancing genetic management of threatened wildlife maintained ex situ. In this study, we used noninvasive fecal hormone monitoring to investigate (1) the influence of pairing with a male on endocrine responses of female maned wolves (Chrysocyon brachyurus) to a GnRH agonist (deslorelin) and (2) the efficiency of recombinant LH (reLH) on ovulation induction in females housed alone. Deslorelin (2.1 mg Ovuplant) was given to females that were either paired with a male (n = 4) or housed alone (n = 7); the implant was removed 7 to 11 days postimplantation...
July 1, 2014: Theriogenology
Amy E M Johnson, Elizabeth W Freeman, David E Wildt, Nucharin Songsasen
We assessed the influences of medium osmolality, cryoprotectant and cooling and warming rate on maned wolf (Chrysocyon brachyurus) spermatozoa. Ejaculates were exposed to Ham's F10 medium (isotonic control) or to this medium plus NaCl (350-1000mOsm), sucrose (369 and 479mOsm), 1M glycerol (1086mOsm) or dimethyl sulfoxide (Me2SO, 1151mOsm) for 10 min. Each sample then was diluted back into Ham's medium and assessed for sperm motility and plasma membrane integrity. Although glycerol and Me2SO had no influence (P>0...
June 2014: Cryobiology
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