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https://www.readbyqxmd.com/read/28294385/potential-excitatory-role-of-nitric-oxide-on-2-deoxy-d-glucose-induced-gastric-motility-in-rats
#1
A M Sevgili, Z D Balkanci, A Erdem
Previous studies have shown that 2-deoxy-d-glucose (2-DG) increases gastric motility via the vagus nerve, but the underlying mechanism remains elusive. Since nitric oxide (NO) is involved in gastric motility, a possible interplay between 2-DG and NO can be suggested. In the present study, Wistar rats (250-350 g) of both sexes were intravenously injected with 2-DG (200 mg·kg(-1) ), and the effects of the intravenous injection of the nitric oxide synthase (NOS) inhibitors; nitro-l-arginine methyl ester (l-NAME, 10 mg·kg(-1) ) and N(ω) -nitro-l-arginine (l-NNA, 10 mg·kg(-1) ) were investigated...
March 13, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/28292405/selected-endoscopic-gastric-devices-for-obesity
#2
REVIEW
Kartik Sampath, Richard I Rothstein
This article focuses on the stomach target devices that are currently in various stages of development. Approved intragastric balloons, devices targeting small bowel and aspiration techniques, are described in other contributions to this issue. Bariatric endoscopic devices targeting the stomach directly alter gastric physiology and promote weight loss by potentially changing functional gastric volume, gastric emptying, gastric wall compliance, neurohormonal signaling, and, thereby, satiety. Many stomach-targeting devices are on the horizon for clinical use, and further study will determine the safety and efficacy for clinical use...
April 2017: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/28292403/intragastric-balloons-in-clinical-practice
#3
REVIEW
Marianna Papademetriou, Violeta Popov
Cost-effective therapies to address the growing epidemic of obesity are a leading priority in modern medicine. Intragastric balloons (IGBs) are one such option, with increased effectiveness compared with pharmacotherapy and lifestyle and a lower rate of adverse events than bariatric surgery. IGBs are endoscopically placed or swallowed space-occupying devices in the stomach. Three IGB systems were approved in 2015 to 2016 by the Food and Drug Administration for use in the United States, with more devices nearing approval...
April 2017: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/28285471/the-influence-of-the-orbera-intragastric-balloon-filling-volumes-on-weight-loss-tolerability-and-adverse-events-a-systematic-review-and-meta-analysis
#4
Nitin Kumar, Fateh Bazerbachi, Tarun Rustagi, Thomas R McCarty, Christopher C Thompson, Manoel P Galvao Neto, Natan Zundel, Erik B Wilson, Christopher J Gostout, Barham K Abu Dayyeh
BACKGROUND: The Orbera intragastric balloon (IGB) has been approved by the US Food and Drug Administration for use in patients with a body mass index (BMI) between 30 and 40 kg/m(2) and is in wide use worldwide as a primary and bridge obesity management tool. The balloon filling volume (BFV) ranges between 400 and 700 mL of saline. Our objective was to determine whether there is an association between BFV and clinically relevant endpoints, namely weight loss outcomes, balloon tolerability, and adverse events...
March 12, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28270675/spontaneous-hyperinflation-of-an-intragastric-balloon-5-months-after-insertion
#5
Sindhu Barola, Abhishek Agnihotri, Angela Chang Chiu, Anthony N Kalloo, Vivek Kumbhari
No abstract text is available yet for this article.
March 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28236255/a-call-for-more-research-from-the-arabian-gulf
#6
Fatemah AlMarri, Salman Al Sabah, Eliana Al Haddad, Jonathan D Vaz
INTRODUCTION: Obesity has become an epidemic in the Arabian Gulf, with the prevalence of obesity according to the latest report from the World Health Organization (WHO) showing the gulf region to be countries with the highest incidence of obesity in the 30% plus group. This study aims to examine publications on bariatric surgery and compare them with the other countries with a high incidence of obesity in the world. METHODS: A literature review on bariatric surgery published from the earliest detected year of publication up until March 2016 using SCOPUS, PubMed, Ovid, and Google Scholar was conducted...
February 24, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28229608/usefulness-of-an-intra-gastric-balloon-before-bariatric-surgery
#7
Cristina Vicente, Luis Ramón Rábago, Alejandro Ortega, Marisa Arias, Jaime Vázquez Echarri
INTRODUCTION: There are only few reports regarding the use of intragastric-balloons (IGB®) to achieve weight loss and subsequently decrease surgical complications. In this study, we try to assess whether presurgery weight loss using IGB decreases the postsurgical mortality after bariatric surgery. METHODS: This is a prospective case-control study. We matched 1:1 by gender, age (± 10 y-o) and type of surgery (sleeve resection [LSG] or gastric bypass [LGBP]), matching cases (A) and controls (H, from a historic cohort)...
February 23, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28180149/the-obalon-swallowable-intragastric-balloon-in-pediatric-and-adolescent-morbid-obesity
#8
Francesco De Peppo, Romina Caccamo, Ottavio Adorisio, Emanuela Ceriati, Paola Marchetti, Antonio Contursi, Arianna Alterio, Claudia Della Corte, Malnia Manco, Valerio Nobili
Background and study aims Incidence of morbid obesity has grown dramatically in the last half century and this phenomenon affects with particular severity the pediatric population. Dietary restrictions and careful programs to improve lifestyle are often ineffective to manage this particular group of patients, due to poor compliance typical of the adolescence. The aim of this study was to evaluate the effectiveness of a new intragastric balloon for treatment of morbidly obese children. Patients and methods A new swallowable intragastric balloon (Obalon) has been used for the first time in 17 obese children in order to assess its safety and effectiveness in terms of reduction in excess weight...
January 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28147471/recent-trends-in-endoscopic-bariatric-therapies
#9
REVIEW
Hyuk Soon Choi, Hoon Jai Chun
Obesity and its associated metabolic diseases including diabetes mellitus are severe medical problems that are increasing in prevalence worldwide and result in significant healthcare expenses. While behavioral and pharmacological treatment approaches are partly effective in the short term, their effects are not long-lasting. Although previous studies have described bariatric surgery as the most effective treatment for obesity, it is associated with morbidity, mortality, and economic burden. Endoluminal interventions performed entirely using gastrointestinal flexible endoscopy offer alternative approaches to the treatment of obesity that are safer and more cost-effective than current surgical approaches...
January 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28119935/gastric-occlusion-due-to-intragastric-balloon-with-gastric-necrosis-and-portal-pneumatosis
#10
Maria Saladich-Cubero, Josep Alayrach Vilella, Yuhamy Curbelo Peña, Meritxell Medarde-Ferrer, Javier De Castro Gutiérrez, Xavier Quer Vall, Enric De Caralt Mestres
No abstract text is available yet for this article.
August 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/28117361/the-impact-of-intragastric-balloons-on-obesity-related-co-morbidities-a-systematic-review-and-meta-analysis
#11
REVIEW
Violeta B Popov, Amy Ou, Allison R Schulman, Christopher C Thompson
ObjectivesTherapies less invasive than surgery and more effective than lifestyle and pharmacotherapy are needed to contend with the obesity epidemic. Intragastric balloons (IGBs) are a minimally invasive endoscopic weight loss method recently approved for use in the US. The purpose of the study is to assess the effect of IGBs on metabolic outcomes associated with obesity.MethodsMEDLINE, Embase, and Cochrane Database were searched through July 2016. Dual extraction and quality assessment of studies using Cochrane risk of bias tool were performed independently by two authors...
March 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28098700/high-risk-of-aspiration-in-patients-with-reshape-intragastric-balloon-weight-loss-system
#12
Mark A Burbridge, Clarity Coffman
No abstract text is available yet for this article.
February 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28070780/laparoscopic-sleeve-gastrectomy-in-adolescents-with-or-without-syndromic-obesity-two-years-follow-up
#13
Angelo Iossa, Francesco De Peppo, Romina Caccamo, Brad Michael Watkins, Francesca Abbatini, Emanuela Ceriati, Gianfranco Silecchia
INTRODUCTION: Childhood obesity is an emerging health problem. Surgical treatment of obese adolescents, particularly those affected by congenital syndrome, represents a controversial issue. The aim of this multicenter study was to retrospectively assess the results of laparoscopic sleeve gastrectomy (LSG) in a cohort of adolescents affected by morbid obesity, with or without congenital syndromes. MATERIALS AND METHODS: Forty-one obese (BMI 49 ± 6 kg/m(2)) adolescents with mean age of 16 ± 3 years (58...
January 9, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28017964/intragastric-balloon-as-an-adjunct-to-lifestyle-intervention-a-randomized-controlled-trial
#14
A Courcoulas, B K Abu Dayyeh, L Eaton, J Robinson, G Woodman, M Fusco, V Shayani, H Billy, D Pambianco, C Gostout
BACKGROUND/OBJECTIVES: This trial evaluated the safety and effectiveness of the Orbera Intragastric Balloon as an adjunct to lifestyle intervention. SUBJECTS/METHODS: In this multicenter, randomized, open-label clinical trial, 255 adults with a body mass index of 30-40 kg m(-)(2) were treated and outcomes were assessed up to 12 months. Participants were randomized to endoscopic placement of an intragastric balloon plus lifestyle or lifestyle intervention alone...
January 24, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28008162/endoscopic-approach-for-major-complications-of-bariatric-surgery
#15
Moon Kyung Joo
As lifestyle and diet patterns have become westernized in East Asia, the prevalence of obesity has rapidly increased. Bariatric surgeries, such as Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG), and laparoscopic adjustable gastric banding (LAGB), are considered the first-line treatment option in patients with severe obesity. However, postoperative complications have increased and the proper management of these complications, including the use of endoscopic procedures, has become important. The most serious complications, such as leaks and fistulas, can be treated with endoscopic stent placement and injection of fibrin glue, and a novel full-thickness closure over-the-scope clip (OTSC) has been used for treatment of postoperative leaks...
January 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28000756/a-magnetic-soft-endoscopic-capsule-inflated-intragastric-balloon-for-weight-management
#16
Thanh Nho Do, Khek Yu Ho, Soo Jay Phee
Overweight and obesity have been identified as a cause of high risk diseases like diabetes and cancer. Although conventional Intragastric Balloons (IGBs) have become an efficient and less invasive method for overweight and obesity treatment, the use of conventional tools such as catheter or endoscope to insert and remove the IGBs from the patient's body causes nausea, vomiting, discomfort, and even gastric mucous damage. To eliminate these drawbacks, we develop a novel magnetic soft capsule device with gas-filled balloon inflation...
December 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27784008/does-intragastric-balloon-treatment-for-obesity-in-chronic-kidney-disease-heighten-acute-kidney-injury-risk
#17
Helen L MacLaughlin, Iain C Macdougall, Wendy L Hall, Tracy Dew, Konstantinos Mantzoukis, Jude A Oben
BACKGROUND: The outcomes of intragastric balloon (IGB) placement to achieve weight loss in obese patients with chronic kidney disease (CKD) have not been reported to date. This study aimed to assess the safety and efficacy of the IGB as a weight-loss treatment among this patient population. METHODS: A prospective, single-arm, 'first in CKD' interventional study was conducted in patients with a body mass index >35 kg/m2 and CKD stages 3-4, referred for weight loss...
2016: American Journal of Nephrology
https://www.readbyqxmd.com/read/27771316/changes-in-physical-activity-after-bariatric-surgery-using-objective-and-self-reported-measures
#18
Sorena Afshar, Keith Seymour, Seamus B Kelly, Sean Woodcock, Vincent T van Hees, John C Mathers
BACKGROUND: Many studies using self-reported physical activity (PA) assessment tools have suggested there is an increase in PA after bariatric surgery. OBJECTIVES: Our aim was to assess PA and sedentary behavior before bariatric surgery and at 6 months after, using subjective and objective tools. SETTING: Bariatric surgery candidates were recruited from a single center. METHODS: Demographic data, medical history, current medications, and anthropometric measurements were recorded...
March 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/27752806/initial-approach-to-childhood-obesity-in-spain-a-multisociety-expert-panel-assessment
#19
Ramon Vilallonga, José Manuel Moreno Villares, Diego Yeste Fernández, Raquel Sánchez Santos, Felipe Casanueva Freijo, Francisco Santolaya Ochando, Nuria Leal Hernando, Albert Lecube Torelló, Luis Antonio Castaño González, Albert Feliu, Gontrand Lopez-Nava, Dolores Frutos, Antonio J Torres Garcia, Juan Carlos Ruiz de Adana
PURPOSE: In recent years, the incidence of childhood obesity in Europe, and Spain in particular, has increased dramatically. Bariatric surgery could play a major role in treating of adolescents with severe obesity. However, no specific guidelines for bariatric surgery currently exist in Spain. METHODS: The Board of the Spanish Society for Obesity Surgery and Metabolic Diseases (SECO) proposed a study of childhood obesity by using the Delphi method. This prospective study involved 60 experts from nine national societies...
October 17, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27743165/increased-proliferative-activity-accompanies-the-local-inflammatory-response-of-gastric-mucosa-after-intragastric-balloon-insertion
#20
Ehab Atef, Khaled Refaat Zalata, Hoda Atef, Ahmed A M Abdel-Hamid
BACKGROUND AND AIM: The use of BioEnterics intragastric balloon (BIB) is progressively increasing, owing to the fact that morbid obesity becomes a global epidemic together with risks of bariatric surgery. Yet, the possible local BIB effect on gastric mucosa is not clearly elucidated. The aim of the current study was to assess the histological changes occurring in the gastric mucosa post-BIB insertion. METHODS: Gastric mucosa biopsy was obtained from 87 cases of morbid obesity both pre-BIB and 6 months post-BIB insertion to compare the local changes by histological and immunohistochemical analysis...
October 14, 2016: Digestive Diseases and Sciences
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