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https://www.readbyqxmd.com/read/29450594/position-paper-for-the-organization-of-ecmo-programs-for-cardiac-failure-in-adults
#1
Darryl Abrams, A Reshad Garan, Akram Abdelbary, Matthew Bacchetta, Robert H Bartlett, James Beck, Jan Belohlavek, Yih-Sharng Chen, Eddy Fan, Niall D Ferguson, Jo-Anne Fowles, John Fraser, Michelle Gong, Ibrahim F Hassan, Carol Hodgson, Xiaotong Hou, Katarzyna Hryniewicz, Shingo Ichiba, William A Jakobleff, Roberto Lorusso, Graeme MacLaren, Shay McGuinness, Thomas Mueller, Pauline K Park, Giles Peek, Vin Pellegrino, Susanna Price, Erika B Rosenzweig, Tetsuya Sakamoto, Leonardo Salazar, Matthieu Schmidt, Arthur S Slutsky, Christian Spaulding, Hiroo Takayama, Koji Takeda, Alain Vuylsteke, Alain Combes, Daniel Brodie
Extracorporeal membrane oxygenation (ECMO) has been used increasingly for both respiratory and cardiac failure in adult patients. Indications for ECMO use in cardiac failure include severe refractory cardiogenic shock, refractory ventricular arrhythmia, active cardiopulmonary resuscitation for cardiac arrest, and acute or decompensated right heart failure. Evidence is emerging to guide the use of this therapy for some of these indications, but there remains a need for additional evidence to guide best practices...
February 15, 2018: Intensive Care Medicine
https://www.readbyqxmd.com/read/29447407/the-feasibility-of-venovenous-ecmo-at-role-2-facilities-in-austere-military-environments
#2
Mohamed A T Mohamed, Tareq Maraqa, Matthew D Bacchetta, Michael McShane, Kenneth L Wilson
Introduction: Venovenous extracorporeal membrane oxygenation (VV-ECMO) has been gaining use to bridge the recovery from acute respiratory distress syndrome (ARDS) refractory to conventional treatment. However, these interventions are often limited to higher echelons of military care. We present a case of lung salvage from severe ARDS in an Afghani soldier with VV-ECMO at a Role-2 (R2) facility in an austere military environment in Afghanistan. Case: A 25-year-old Afghani soldier presented to an R2 facility with blast lung injury and multiple penetrating injuries following an explosion...
February 13, 2018: Military Medicine
https://www.readbyqxmd.com/read/29446472/hantavirus-induced-cardiopulmonary-syndrome-a-public-health-concern
#3
REVIEW
Sibghat Tul Llah, Sheema Mir, Sumaiya Sharif, Salman Khan, Mohammed A Mir
Hantavirus cardiopulmonary syndrome is characterized by pulmonary capillary leakage and alveolar flooding, resulting in 50% mortality due to fulminant hypoxic respiratory failure. In addition, depression of cardiac function ensues, which complicates the picture with cardiogenic shock. Early diagnosis and appropriate use of extracorporeal membrane oxygenation (ECMO) are amongst the lifesaving interventions in this fatal illness. However, a recent case report demonstrates that implementation of high volume continuous hemofilteration along with protective ventilation reverses the cardiogenic shock within few hours in hantavirus infected patients...
February 15, 2018: Journal of Medical Virology
https://www.readbyqxmd.com/read/29445475/endogenous-carbon-monoxide-production-in-extracorporeal-membrane-oxygenation-related-hemolysis-potential-use-of-point-of-care-co-oximetry-carboxyhemoglobin-to-detect-hemolysis
#4
Chan Kai Man, Lam Koon Ngai
Extracorporeal membrane oxygenation (ECMO)-related hemolysis is a rare but devastating condition. Death is inevitable without early recognition and prompt management. Endogenous carbon monoxide production, as an epiphenomenon of hemolysis, potentially allows rapid detection of such condition by use of point-of-care CO-oximetry carboxyhemoglobin.
February 2018: Clinical Case Reports
https://www.readbyqxmd.com/read/29444222/extracorporeal-membrane-oxygenation-as-a-bridge-to-lung-transplantation-may-not-impact-overall-mortality-risk-after-transplantation-results-from-a-7-year-single-centre-experience
#5
Fabio Ius, Ruslan Natanov, Jawad Salman, Christian Kuehn, Wiebke Sommer, Murat Avsar, Thierry Siemeni, Dmitry Bobylev, Reza Poyanmehr, Dietmar Boethig, Joerg Optenhoefel, Nicolaus Schwerk, Axel Haverich, Gregor Warnecke, Igor Tudorache
OBJECTIVES: Extracorporeal membrane oxygenation (ECMO) has an important role in bridging patients to lung transplantation. In this study, we present our experience with pretransplant ECMO during the last 7 years and investigate its impact on graft outcomes. METHODS: Records of all lung-transplanted patients at our institution between January 2010 and April 2017 were retrospectively reviewed. Graft survival was compared between patients who required pretransplant ECMO (pre-Tx ECMO+) and patients who did not (pre-Tx ECMO-)...
February 12, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29443864/past-and-present-role-of-ecmo-in-combat-casualty-care-how-far-will-we-go
#6
Jeremy W Cannon, Phillip E Mason, Andriy I Batchinsky
Advanced extracorporeal therapies have been successfully applied in the austere environment of combat casualty care over the previous decade. In this review, we describe the historic underpinnings of extracorporeal membrane oxygenation (ECMO), review the recent experience with both partial and full lung support during combat operations, and critically assess both the current status of the Department of Defense ECMO program and the way forward to establish long-range lung rescue therapy as a routine capability for combat casualty care...
February 13, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29440824/extracorporeal-membrane-oxygenation-in-pediatric-cardiac-surgery-a-retrospective-review-of-trends-and-outcomes-in-scotland
#7
Maziar Khorsandi, Mark Davidson, Omar Bouamra, Andrew McLean, Kenneth MacArthur, Ida Torrance, Gillian Wylie, Ed Peng, Mark Danton
Introduction: Around 3.2%-8.4% of patients receive venoarterial (VA) extracorporeal membrane oxygenation (ECMO) support after pediatric cardiac surgery. The desired outcome is "bridge-to-recovery" in most cases. There is no universally agreed protocol, and given the associated costs and complications rates, the decisions as of when and when not to institute VA ECMO are largely empirical. Methods: A retrospective review of the ECMO database at the Scottish Pediatric Cardiac Services (SPCS) was undertaken...
January 2018: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/29436001/effects-of-pulsatile-blood-flow-on-oxygenator-performance
#8
Lotte Schraven, Andreas Kaesler, Christian Flege, Rüdger Kopp, Thomas Schmitz-Rode, Ulrich Steinseifer, Jutta Arens
Extracorporeal membrane oxygenation (ECMO) is mainly used for the therapy of acute respiratory distress syndrome and chronic obstructive lung disease. In the last years, the development of these systems underwent huge steps in optimization, but there are still problems with thrombus formation, clogging, and thus insufficient gas exchange. One idea of ECMO optimization is a pulsatile blood flow through the oxygenator, but this is still a controversy discussion. Analyzing available publications, it was not possible to identify a general statement about the effect of pulsatile blood flow on the gas exchange performance...
February 13, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29435994/evaluation-of-the-novel-centrifugal-pump-capiox-sl-in-chronic-large-animal-experiments
#9
Kei Iizuka, Nobumasa Katagiri, Yoshiaki Takewa, Tomonori Tsukiya, Toshihide Mizuno, Yosuke Itamochi, Kouko Kumano, Eisuke Tatsumi
In the development of a new device for extracorporeal circulation, long-term durability and biocompatibility are required. The CAPIOX SL Pump (SL pump, Terumo Corporation, Tokyo, Japan), which is a centrifugal pump using a two-pivot bearing, was developed with the hope of suppressing pump thrombus formation around the bearings. This study aimed to evaluate the in vivo performance of the SL pump in the condition assumed severe clinical situation for long-term extracorporeal membrane oxygenation (ECMO) support...
February 12, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29434806/extracorporeal-membrane-oxygenation-support-for-a-multitrauma-patient-with-ards-a-case-report-and-literature-review
#10
Yuexing Tu, Qi Jin, Renhua Sun, Qian Li
Extracorporeal membrane oxygenation (ECMO) provides rescue treatment for patients with severe acute respiratory distress syndrome (ARDS) when conventional management fails. The present study reported ECMO as a life-saving treatment for ARDS due to bilateral pulmonary contusion in a 24-year-old male multiple trauma patient. ECMO therapy lasted 7 days for the patient and was successively stopped without any complications. ECMO modality should be chosen according to the respiratory and circulatory condition of each individual...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29429200/-outcome-of-pediatric-extracorporeal-membrane-oxygenation-in-a-single-center
#11
Q Bao, X Y Hong, Y Y Liu, X J Zhang, H T Gao, Z C Feng
Objective: To investigate the application and outcome of pediatric extracorporeal membrane oxygenation (ECMO) in a single center. Methods: The clinical data of 52 pediatric patients with cardiopulmonary failure received ECMO support in Bayi Children's Hospital Affiliated to General Hospital of Beijing Military Command of PLA were collected from January 2012 to October 2016. All patients were divided into two stages by time. January 2012 to December 2014 was stage one. January 2015 to October 2016 was stage two...
February 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29428358/central-veno-arterial-extracorporeal-membrane-oxygenation-c-va-ecmo-after-cardiothoracic-surgery-a-single-center-experience
#12
Antonio Rubino, Diego Costanzo, Daniel Stanszus, Kamen Valchanov, David Jenkins, Federico Sertic, Jo-Anne Fowles, Alain Vuylsteke
OBJECTIVES: Central veno-arterial extracorporeal membrane oxygenation (C-VA-ECMO) provides temporary cardiorespiratory support for patients in heart failure who cannot be weaned from cardiopulmonary bypass successfully. Outcomes are influenced by the reversibility of the initial insult and complications of the technique. METHODS: The authors reviewed their single-center experience over the last 8 years to inform future practice. The study included all patients supported with C-VA-ECMO after cardiothoracic surgery between January 2008 and July 2016...
December 6, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29422067/predictors-of-hospital-mortality-in-adult-trauma-patients-receiving-extracorporeal-membrane-oxygenation-for-advanced-life-support-a-retrospective-cohort-study
#13
Meng-Yu Wu, Pin-Li Chou, Tzu-I Wu, Pyng-Jing Lin
BACKGROUND: Using extracorporeal membrane oxygenation (ECMO) to provide advanced life support in adult trauma patients remains a controversial issue now. The study was aimed at identifying the independent predictors of hospital mortality in adult trauma patients receiving ECMO for advanced cardiopulmonary dysfunctions. METHODS: This retrospective study enrolled 36 adult trauma patients receiving ECMO due to advanced shock or respiratory failure in a level I trauma center between August 2006 and October 2014...
February 8, 2018: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/29420842/acute-myocardial-infarction-complicated-with-ventricular-septal-rupture-and-intracranial-hemorrhage
#14
Munevver Sari, Gokhan Kahveci, Alev Kilicgedik, Mehmet Ayturk, Selcuk Pala
Ventricular septal rupture (VSR) is a rare but fatal complication of acute myocardial infarction (AMI) with an associated mortality that ranges from 41% to 80%. The treatment consists of supplemental oxygenation, afterload reduction, intraaortic balloon pump, and surgical repair. In selected patients, extracorporeal membrane oxygenation (ECMO) and/or percutaneous closure of the defect can be considered if anatomically appropriate. Echocardiography evaluates the morphology and location of the defect, anatomical concerns for percutaneous closure, and accompanying pathologies...
February 8, 2018: Echocardiography
https://www.readbyqxmd.com/read/29419538/percutaneous-mechanical-circulation-support-combined-with-extracorporeal-membrane-oxygenation-oxyrvad-in-secondary-right-heart-failure
#15
Philipp M Lepper, Sabrina I Hörsch, Frederik Seiler, Annegret Kamp, Sören L Becker, Christian Lensch, Lars O Conzelmann, Hendrik Haake, Ralf M Muellenbach, Robert Bals, Markus Kredel, Frank Langer, Heinrike Wilkens, Franziska C Trudzinski
Right heart failure (RHF) because of pulmonary hypertension (PH) is a frequently encountered clinical problem with high mortality. The last resort, if pharmacological therapy fails, is mechanical circulatory support. There is a lack of percutaneous systems to support the right ventricle (RV). Venoarterial extracorporeal membrane oxygenation is widely used as a bailout in acute RHF in non-left ventricular assist device patients. Venoarterial extracorporeal membrane oxygenation does not unload the left ventricle and may cause failure of the left ventricle if used for a longer period of time...
February 6, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29409389/weaning-adult-patients-with-cardiogenic-shock-on-veno-arterial-extracorporeal-membrane-oxygenation-by-pump-controlled-retrograde-trial-off
#16
Lowell Ling, Kai Man Chan
BACKGROUND: There is a lack of consensus on the timing of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) liberation. VA-ECMO weaning usually consists of serial decrements until an idling flow is achieved, supported by echocardiographic and haemodynamic assessments. Even with minimal idling flow, right ventricular (RV) preload is reduced and, hence, right heart function is not fully tested under adequate loading conditions. Following the use of a novel technique called Pump Controlled Retrograde Trial Off (PCRTO) in neonate VA-ECMO weaning, we report the use of this technique in seven adult patients on VA-ECMO...
February 1, 2018: Perfusion
https://www.readbyqxmd.com/read/29404795/prolonged-extracorporeal-membrane-oxygenation-for-pediatric-necrotizing-pneumonia-due-to-streptococcus-pneumonia-and-influenza-h1n1-co-infection-how-long-should-we-wait-for-native-lung-recovery
#17
Gerard Cortina, Christian Niederwanger, Uwe Klingkowski, Corinna Velik-Salchner, Nikolaus Neu
Most children with severe respiratory failure require extracorporeal membrane oxygenation (ECMO) for 7-10 days. However, some may need prolonged duration ECMO (> 14 days). To date, no consensus exists on how long to wait for native lung recovery. Here we report the case of a 3-year-old boy who developed severe necrotizing pneumonia requiring venovenous (VV) ECMO after 19 days of mechanical ventilation. In the first 4 weeks of his ECMO run, he showed no lung aeration, requiring total extracorporeal support...
February 5, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29399566/predictive-value-of-procalcitonin-for-infection-and-survival-in-adult-cardiogenic-shock-patients-treated-with-extracorporeal-membrane-oxygenation
#18
Do Wan Kim, Hwa Jin Cho, Gwan Sic Kim, Sang Yun Song, Kook Joo Na, Sang Gi Oh, Bong Suk Oh, In Seok Jeong
Procalcitonin (PCT) is a predictive marker for the occurrence of bacterial infection and the decision to terminate antibiotic treatment in critically ill patients. An unusual increase in PCT, regardless of infection, has been observed during extracorporeal membrane oxygenation (ECMO) support. We evaluated trends and the predictive value of PCT levels in adult cardiogenic shock during treatment with ECMO. We reviewed the clinical records of 38 adult cardiogenic shock patients undergoing veno-arterial ECMO support between January 2014 and December 2016...
January 2018: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29395370/adequacy-of-nutrition-support-during-extracorporeal-membrane-oxygenation
#19
Liisa MacGowan, Elizabeth Smith, Charmaine Elliott-Hammond, Barnaby Sanderson, Dennis Ong, Kathleen Daly, Nicholas A Barrett, Kevin Whelan, Danielle E Bear
BACKGROUND: The use of veno-venous extracorporeal membrane oxygenation (vv-ECMO) is increasing in adults with severe respiratory failure. Observational data suggest that there are significant challenges to providing adequate nutrition support for patients on vv-ECMO. We aimed to describe firstly the nutrition support practices in a large single-centre providing vv-ECMO to adults and secondly any association with clinical outcome. METHODS: We conducted a retrospective review of patients receiving vv-ECMO on the Intensive Care Unit (ICU) of a large London teaching hospital...
January 26, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29395201/duration-of-extracorporeal-membrane-oxygenation-support-and-survival-in-cardiovascular-surgery-patients
#20
Klaus Distelmaier, Dominik Wiedemann, Christina Binder, Thomas Haberl, Daniel Zimpfer, Gottfried Heinz, Herbert Koinig, Alessia Felli, Barbara Steinlechner, Alexander Niessner, Günther Laufer, Irene M Lang, Georg Goliasch
OBJECTIVE: The overall therapeutic goal of venoarterial extracorporeal membrane oxygenation (ECMO) in patients with postcardiotomy shock is bridging to myocardial recovery. However, in patients with irreversible myocardial damage prolonged ECMO treatment would cause a delay or even withholding of further permanent potentially life-saving therapeutic options. We therefore assessed the prognostic effect of duration of ECMO support on survival in adult patients after cardiovascular surgery...
December 26, 2017: Journal of Thoracic and Cardiovascular Surgery
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