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https://www.readbyqxmd.com/read/28231513/increasing-ascorbate-levels-in-crops-to-enhance-human-nutrition-and-plant-abiotic-stress-tolerance
#1
REVIEW
Richard C Macknight, William A Laing, Sean M Bulley, Ronan C Broad, Alexander At Johnson, Roger P Hellens
Ascorbate (or vitamin C) is an essential human micronutrient predominantly obtained from plants. In addition to preventing scurvy, it is now known to have broader roles in human health, for example as a cofactor for enzymes involved in epigenetic programming and as regulator of cellular iron uptake. Furthermore, ascorbate is the major antioxidant in plants and underpins many environmentally induced abiotic stress responses. Biotechnological approaches to enhance the ascorbate content of crops therefore have potential to improve both human health and abiotic stress tolerance of crops...
February 20, 2017: Current Opinion in Biotechnology
https://www.readbyqxmd.com/read/28217165/headband-sign-on-magnetic-resonance-imaging-an-unusual-finding-of-scurvy-in-a-5-year-old-child-described-first-time
#2
Umesh I Patel, Jayendra R Gohil, Alpa N Parekh, Hardik R Chauhan
Scurvy usually presents with tender and painful limbs, swelling of joints, gum bleeding, poor wound healing, and muscle weakness. Here, we report a case of 5-year-old child with global developmental delay who presented with soft swelling of the head over scalp and protrusion of the left eye with extremely irritability. Neuroimaging was suggestive of diffuse extensive soft-tissue swelling involving the entire scalp with large necrotic collections with mild proptosis of the left orbit. It is not mentioned elsewhere, so we are giving name to this magnetic resonance imaging finding as "headband" sign or "turban" sign...
October 2016: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/28216897/high-performance-liquid-chromatography-diode-array-detector-method-for-the-simultaneous-determination-of-five-compounds-in-the-pulp-and-seed-of-sea-buckthorn
#3
Lu Zhao, E Wen, Halmuart Upur, Shuge Tian
CONTEXT: Sea buckthorn (Hippophae rhamnoides L.) as a traditional Chinese medicinal plant has various uses in Xinjiang. OBJECTIVE: A reversed-phase rapid-resolution liquid-chromatography method with diode array detector was developed for simultaneous determination of protocatechuic acid, rutin, quercetin, kaempferol, and isorhamnetin in the pulp and seed of sea buckthorn, a widely used traditional Chinese medicine for promoting metabolism and treating scurvy and other diseases...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28101580/crude-extract-and-solvent-fractions-of-calystegia-soldanella-induce-g1-and-s%C3%A2-phase-arrest-of-the-cell-cycle-in-hepg2-cells
#4
Jung Im Lee, In-Hye Kim, Taek-Jeong Nam
The representative halophyte Calystegia soldanella (L) Roem. et Schult is a perennial vine herb that grows in coastal dunes throughout South Korea as well as in other regions around the world. This plant has long been used as an edible and medicinal herb to cure rheumatic arthritis, sore throat, dropsy, and scurvy. Some studies have also shown that this plant species exhibits various biological activities. However, there are few studies on cytotoxicity induced by C. soldanella treatment in HepG2 human hepatocellular carcinoma cells...
February 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/28087031/dermoscopic-diagnosis-of-scurvy
#5
Carlos Gustavo Wambier, Mark Aaron Cappel, Betina Werner, Erika Rodrigues, Mariana Sandri Schumacher Welling, Mário Rodrigues Montemór Netto, Sarah Perillo de Farias Wambier
No abstract text is available yet for this article.
February 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27927640/sixty-seconds-on-scurvy
#6
Susan Mayor
No abstract text is available yet for this article.
December 7, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27915106/insights-gained-from-ancient-biomolecules-into-past-and-present-tuberculosis-a-personal-perspective
#7
REVIEW
Helen D Donoghue
Ancient and historical tuberculosis (TB) can be recognized by its typical paleopathology in human remains. Using paleomicrobiology, it is possible to detect many more individuals infected with TB but with no visible lesions. Due to advances in molecular analysis over the past two decades, it is clear that TB was widespread in humans from the Neolithic period and has remained so until the present day. Past human populations were associated with different lineages of the Mycobacterium tuberculosis complex, thereby elucidating early human migrations...
November 30, 2016: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/27859562/vitamin%C3%A2-c-deficiency-and-diabetes-mellitus-easily-missed
#8
D J Christie-David, J E Gunton
Scurvy and vitamin C deficiency are usually considered to be of only historical interest. Interestingly, most animals can synthesize vitamin C, but not humans, higher primates, guinea-pigs and some bats. Deficiency results in the defective formation of collagen and connective tissues; symptoms of deficiency may include bruising, bleeding gums, petechiae, arthralgia and impaired wound healing [1,2]. This article is protected by copyright. All rights reserved.
November 18, 2016: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/27851280/1645-cardiac-arrest-and-pulmonary-hypertension-in-scurvy-a-case-report
#9
Terry Dean, Neeru Kaushik, Sharon Williams, Jeffrey Fineman, Paul Kim
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27836062/back-to-the-future-1753-vitamin-c-remediates-scurvy-2016-folinic-acid-does-the-same-for-mthfd1-scid-with-the-help-of-exome-sequencing
#10
EDITORIAL
Roger H Kobayashi
No abstract text is available yet for this article.
November 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27795777/systematic-reviews-in-context-highlighting-systematic-reviews-relevant-to-africa-in-the-pan-african-medical-journal
#11
Charles Shey Wiysonge, Raoul Kamadjeu, Landry Tsague
Health research serves to answer questions concerning health and to accumulate facts (evidence) required to guide healthcare policy and practice. However, research designs vary and different types of healthcare questions are best answered by different study designs. For example, qualitative studies are best suited for answering questions about experiences and meaning; cross-sectional studies for questions concerning prevalence; cohort studies for questions regarding incidence and prognosis; and randomised controlled trials for questions on prevention and treatment...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27778040/modern-american-scurvy-experience-with-vitamin-c-deficiency-at-a-large-children-s-hospital
#12
Farahnaz Golriz, Lane F Donnelly, Sridevi Devaraj, Raj Krishnamurthy
BACKGROUND: Until recently scurvy has been viewed in developed countries as a disease of the past. More recently there have been reports of case series of children with scurvy who have had a delayed diagnosis after an extensive diagnostic workup that included imaging. Most of these children have had underlying neurologic conditions such as autism. OBJECTIVE: To review the medical records of children diagnosed with vitamin C (ascorbic acid) deficiency based on serum ascorbic acid levels at a large pediatric health care system, to determine imaging findings and utility of imaging in management, and to identify at-risk pediatric populations...
February 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/27726750/imaging-findings-of-metabolic-bone-disease
#13
Connie Y Chang, Daniel I Rosenthal, Deborah M Mitchell, Atsuhiko Handa, Susan V Kattapuram, Ambrose J Huang
Metabolic bone diseases are a diverse group of diseases that result in abnormalities of (a) bone mass, (b) structure mineral homeostasis, (c) bone turnover, or (d) growth. Osteoporosis, the most common metabolic bone disease, results in generalized loss of bone mass and deterioration in the bone microarchitecture. Impaired chondrocyte development and failure to mineralize growth plate cartilage in rickets lead to widened growth plates and frayed metaphyses at sites of greatest growth. Osteomalacia is the result of impaired mineralization of newly formed osteoid, which leads to characteristic Looser zones...
October 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/27682441/reversible-right-heart-failure-in-scurvy-rediscovery-of-an-old-observation
#14
Farrukh Abbas, Le Dung Ha, Richard Sterns, Laura von Doenhoff
No abstract text is available yet for this article.
October 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27673049/poster-293-pain-and-weakness-due-to-scurvy-and-other-vitamin-deficiencies-a-case-report
#15
Christine Chan, Sarah Eby
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27529239/vitamin-c-and-heart-health-a-review-based-on-findings-from-epidemiologic-studies
#16
REVIEW
Melissa A Moser, Ock K Chun
Vitamin C is a powerful dietary antioxidant that has received considerable attention in the literature related to its possible role in heart health. Although classical vitamin C deficiency, marked by scurvy, is rare in most parts of the world, some research has shown variable heart disease risks depending on plasma vitamin C concentration, even within the normal range. Furthermore, other studies have suggested possible heart-related benefits to vitamin C taken in doses beyond the minimal amounts required to prevent classically defined deficiency...
August 12, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27503863/scurvy-and-the-enhancement-of-the-senses
#17
Jonathan Lamb
No abstract text is available yet for this article.
August 8, 2016: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/27502755/-atypical-scurvy-associated-with-anorexia-nervosa
#18
R André, A Gabrielli, E Laffitte, O Kherad
INTRODUCTION: Scurvy, or "Barlow's disease", is a widely described disease involving cutaneous and mucosal lesions resulting from vitamin C deficiency. Herein, we report a case of scurvy in a 48-year-old woman that was unusual in its atypical cutaneous-mucosal presentation as well as its association with anorexia nervosa. PATIENTS AND METHODS: A 48-year-old woman treated for depression for several years was admitted to hospital for her impaired general state of health...
February 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/27426835/scurvy-from-a-selective-diet-in-children-with-developmental-delay
#19
Megumi Seya, Atsuhiko Handa, Daisuke Hasegawa, Toshihiro Matsui, Taiki Nozaki
No abstract text is available yet for this article.
October 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27416817/a-case-of-scurvy-uncommon-disease-presenting-as-panniculitis-purpura-and-oligoarthritis
#20
Danielle Mintsoulis, Nataliya Milman, Simone Fahim
IMPORTANCE: Scurvy remains prevalent in certain populations, including addicts, people of low socioeconomic status, and the severely malnourished. It classically presents as follicular hyperkeratosis and perifollicular hemorrhage of the lower extremities, as well as bleeding in other areas such as the gingiva and joints. This case presentation and literature review highlights the common pathophysiological findings associated with scurvy and current methods of diagnosis and treatment. OBSERVATION: The patient described in this case presented with sudden oligoarthritis and purpura of the lower extremities...
November 2016: Journal of Cutaneous Medicine and Surgery
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