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Motivation and learning

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https://www.readbyqxmd.com/read/27911344/patient-perspectives-on-deep-brain-stimulation-clinical-research-in-early-stage-parkinson-s-disease
#1
Lauren Heusinkveld, Mallory Hacker, Maxim Turchan, Madelyn Bollig, Christina Tamargo, William Fisher, Lauren McLaughlin, Adria Martig, David Charles
The FDA approved a multicenter, double-blind, Phase III, pivotal trial testing deep brain stimulation in 280 people with very early stage Parkinson's disease (PD; IDE#G050016). In partnership with The Michael J. Fox Foundation for Parkinson's Research, we conducted a survey to investigate motivating factors, barriers, and gender differences for participation in a trial testing DBS in early PD. The majority of survey respondents (72%) indicated they would consider learning more about participating. Men and women with early PD are likely to consider enrolling in trials of invasive therapies that may slow symptom progression and help future patients...
November 30, 2016: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/27910723/powered-mobility-intervention-understanding-the-position-of-tool-use-learning-as-part-of-implementing-the-alp-tool
#2
Lisbeth Nilsson, Josephine Durkin
PURPOSE: To explore the knowledge necessary for adoption and implementation of the Assessment of Learning Powered mobility use (ALP) tool in different practice settings for both adults and children. To consult with a diverse population of professionals working with adults and children, in different countries and various settings; who were learning about or using the ALP tool, as part of exploring and implementing research findings. METHOD: Classical grounded theory with a rigorous comparative analysis of data from informants together with reflections on our own rich experiences of powered mobility practice and comparisons with the literature...
December 2, 2016: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/27909854/does-everyone-s-motivational-beliefs-about-physical-science-decline-in-secondary-school-heterogeneity-of-adolescents-achievement-motivation-trajectories-in-physics-and-chemistry
#3
Ming-Te Wang, Angela Chow, Jessica Lauren Degol, Jacquelynne Sue Eccles
Students' motivational beliefs about learning physical science are critical for achieving positive educational outcomes. In this study, we incorporated expectancy-value theory to capture the heterogeneity of adolescents' motivational trajectories in physics and chemistry from seventh to twelfth grade and linked these trajectories to science-related outcomes. We used a cross-sequential design based on three different cohorts of adolescents (N = 699; 51.5 % female; 95 % European American; M ages for youngest, middle, and oldest cohorts at the first wave = 13...
December 1, 2016: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/27909395/reversal-learning-in-humans-and-gerbils-dynamic-control-network-facilitates-learning
#4
Christian Jarvers, Tobias Brosch, André Brechmann, Marie L Woldeit, Andreas L Schulz, Frank W Ohl, Marcel Lommerzheim, Heiko Neumann
Biologically plausible modeling of behavioral reinforcement learning tasks has seen great improvements over the past decades. Less work has been dedicated to tasks involving contingency reversals, i.e., tasks in which the original behavioral goal is reversed one or multiple times. The ability to adjust to such reversals is a key element of behavioral flexibility. Here, we investigate the neural mechanisms underlying contingency-reversal tasks. We first conduct experiments with humans and gerbils to demonstrate memory effects, including multiple reversals in which subjects (humans and animals) show a faster learning rate when a previously learned contingency re-appears...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27909103/habenula-induced-inhibition-of-midbrain-dopamine-neurons-is-diminished-by-lesions-of-the-rostromedial-tegmental-nucleus
#5
P Leon Brown, Heather Palacorolla, Dana Brady, Katelyn Riegger, Greg I Elmer, Paul D Shepard
: Neurons in the lateral habenula (LHb) are transiently activated by aversive events and have been implicated in associative learning. Functional changes associated with tonic and phasic activation of the LHb are often attributed to a corresponding inhibition of midbrain dopamine (DA) neurons. Activation of GABAergic neurons in the rostromedial tegmental nucleus (RMTg), a region that receives dense projections from the LHb and projects strongly to midbrain monoaminergic nuclei, is believed to underlie the transient inhibition of DA neurons attributed to activation of the LHb...
December 1, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27909022/development-and-evaluation-of-the-tigriopus-course-based-undergraduate-research-experience-impacts-on-students-content-knowledge-attitudes-and-motivation-in-a-majors-introductory-biology-course
#6
Jeffrey T Olimpo, Ginger R Fisher, Sue Ellen DeChenne-Peters
Within the past decade, course-based undergraduate research experiences (CUREs) have emerged as a viable mechanism to enhance novices' development of scientific reasoning and process skills in the science, technology, engineering, and mathematics disciplines. Recent evidence within the bioeducation literature suggests that student engagement in such experiences not only increases their appreciation for and interest in scientific research but also enhances their ability to "think like a scientist." Despite these critical outcomes, few studies have objectively explored CURE versus non-CURE students' development of content knowledge, attitudes, and motivation in the discipline, particularly among nonvolunteer samples...
2016: CBE Life Sciences Education
https://www.readbyqxmd.com/read/27908840/prescription-opioid-taper-support-for-outpatients-with-chronic-pain-a-randomized-controlled-trial
#7
Mark D Sullivan, Judith A Turner, Cory DiLodovico, Angela D'Appolonio, Kari Stephens, Ya-Fen Chan
Patients receiving long-term opioid therapy for chronic pain and interested in tapering their opioid dose were randomly assigned to a 22-week taper support intervention (psychiatric consultation, opioid dose tapering, and 18 weekly meetings with a physician assistant to explore motivation for tapering and learn pain self-management skills) or usual care (N=35). Assessments were conducted at baseline and 22 and 34 weeks after randomization. Using an intention-to-treat approach, we constructed linear regression models to compare groups at each follow-up...
November 28, 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/27906668/an-analysis-of-factors-affecting-mature-age-students-academic-success-in-undergraduate-nursing-programs-a-critical-literature-review
#8
Lisa J Hayden, Sarah Y Jeong, Carol A Norton
The population of mature age students entering university nursing programs has steadily increased in both Australia and worldwide. The objective of the literature review was to explore how mature age students perform academically and to analyse the factors associated with their academic performance in nursing programs. A literature search was conducted in the following databases: CINAHL, ProQuest, Medline, Cochrane, Mosby's Index, Joanna Briggs Institute (JBI), and Scopus. Twenty-six (26) research papers published between 2000 and 2014 have met the selection criteria of this review...
January 1, 2016: International Journal of Nursing Education Scholarship
https://www.readbyqxmd.com/read/27906494/alcohol-dependent-molecular-adaptations-of-the-nmda-receptor-system
#9
REVIEW
Nadege Morisot, Dorit Ron
Phenotypes such as motivation to consume alcohol, goal-directed alcohol seeking and habit formation contribute to the mechanisms underlying heavy alcohol use. Learning and memory processes greatly contribute to the establishment and maintenance of these behavioral phenotypes. The N-Methyl-D-Aspartate receptor (NMDAR) is a driving force of synaptic plasticity, a key cellular hallmark of learning and memory. Here, we describe data in rodents and humans linking signaling molecules that center around the NMDARs and behaviors associated with the development and/or maintenance of alcohol abuse...
December 1, 2016: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/27900507/-why-throw-away-something-useful-attitudes-and-opinions-of-people-treated-for-bipolar-disorder-and-their-relatives-on-organ-and-tissue-donation
#10
Carolina S Padoan, Lucas F Garcia, Aline A Rodrigues, Lucas M Patusco, Mariana V Atz, Flavio Kapczinski, José R Goldim, Pedro V S Magalhães
In regard to mental illness, brain donation is essential for the biological investigation of central pathology. Nevertheless, little is known about the thoughts of people with mental disorders on tissue donation for research. Here, our objective was to understand the attitudes and opinions of people treated for bipolar disorder and their relatives regarding donation in general, and particularly donation for research. This is a qualitative study that used in-depth interviews to determine the thoughts of participants regarding tissue donation for research...
November 29, 2016: Cell and Tissue Banking
https://www.readbyqxmd.com/read/27900481/trial-by-trial-switching-between-procedural-and-declarative-categorization-systems
#11
Matthew J Crossley, Jessica L Roeder, Sebastien Helie, F Gregory Ashby
Considerable evidence suggests that human category learning recruits multiple memory systems. A popular assumption is that procedural memory is used to form stimulus-to-response mappings, whereas declarative memory is used to form and test explicit rules about category membership. The multiple systems framework has been successful in motivating and accounting for a broad array of empirical observations over the past 20 years. Even so, only a couple of studies have examined how the different categorization systems interact...
November 30, 2016: Psychological Research
https://www.readbyqxmd.com/read/27899828/pharmacy-educator-motives-to-pursue-pedagogical-knowledge
#12
Patricia Baia, Aimee F Strang
Objective. To investigate motives of pharmacy educators who pursue pedagogical knowledge through professional development programs and to develop a model of motivation to inform future development. Methods. A mixed-methods approach was used to study both qualitative and quantitative data. Written narratives, postmodule quizzes, and survey data were collected during a 5-year period (2010-2014) from pharmacy educators who participated in an online professional development program titled Helping Educators Learn Pedagogy (HELP)...
October 25, 2016: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/27899333/abnormalities-of-brain-neural-circuits-related-to-obesity-a-diffusion-tensor-imaging-study
#13
Ioannis Papageorgiou, Loukas G Astrakas, Vassileios Xydis, George Alexiou, Panagiotis Bargiotas, Loukia Tzarouchi, Anastasia K Zikou, Dimitrios N Kiortsis, Maria I Argyropoulou
PURPOSE: Increased Body-Mass-Index (BMI) has been associated with brain atrophy in both gray and white matter structures. However, little is known concerning the integrity of white matter tracts in obesity. The purpose of the study was to evaluate the pattern of changes in white matter microstructure in human adiposity. MATERIAL AND METHODS: The study included 268 participants (52 obese, 96 overweight and 120 normal-weight) that were retrospectively evaluated by Diffusion Tensor Imaging...
November 26, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27897764/nursing-students-perceptions-of-effective-problem-based-learning-tutors
#14
Nancy Matthew-Maich, Lynn Martin, Cynthia Hammond, Amy Palma, Maria Pavkovic, Darlene Sheremet, Carmen Roche
Aim To explore baccalaureate nursing students' perceptions of what makes an effective tutor in problem-based learning courses, and the influence of effective teaching on students' learning and experience. Method Students enrolled in all four years of a baccalaureate nursing programme completed online surveys (n=511) and participated in focus groups (n=19). Data were analysed and combined using content analysis. Findings The data were summarised using five themes, the '5 Ps' of effective teaching in problem-based learning...
November 16, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27895719/drabal-novel-method-to-mine-large-high-throughput-screening-assays-using-bayesian-active-learning
#15
Othman Soufan, Wail Ba-Alawi, Moataz Afeef, Magbubah Essack, Panos Kalnis, Vladimir B Bajic
BACKGROUND: Mining high-throughput screening (HTS) assays is key for enhancing decisions in the area of drug repositioning and drug discovery. However, many challenges are encountered in the process of developing suitable and accurate methods for extracting useful information from these assays. Virtual screening and a wide variety of databases, methods and solutions proposed to-date, did not completely overcome these challenges. This study is based on a multi-label classification (MLC) technique for modeling correlations between several HTS assays, meaning that a single prediction represents a subset of assigned correlated labels instead of one label...
2016: Journal of Cheminformatics
https://www.readbyqxmd.com/read/27895602/motivational-and-behavioral-activation-as-an-adjunct-to-psychiatric-rehabilitation-for-mild-to-moderate-negative-symptoms-in-individuals-with-schizophrenia-a-proof-of-concept-pilot-study
#16
Kee-Hong Choi, Eunju Jaekal, Ga-Young Lee
Few psychosocial approaches address the negative symptoms of schizophrenia, which shares common features with depression and anxiety. Behavioral activation (BA) is effective for addressing depression and anxiety in adults with various mental disorders. Motivational interviewing (MI) has been successfully applied to address ambivalence or lack of motivation toward treatment. Motivational and behavioral activation (mBA) has been developed by incorporating the core principles from BA and MI with recent findings on the negative symptoms of schizophrenia...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27895562/brain-computation-is-organized-via-power-of-two-based-permutation-logic
#17
Kun Xie, Grace E Fox, Jun Liu, Cheng Lyu, Jason C Lee, Hui Kuang, Stephanie Jacobs, Meng Li, Tianming Liu, Sen Song, Joe Z Tsien
There is considerable scientific interest in understanding how cell assemblies-the long-presumed computational motif-are organized so that the brain can generate intelligent cognition and flexible behavior. The Theory of Connectivity proposes that the origin of intelligence is rooted in a power-of-two-based permutation logic (N = 2 (i) -1), producing specific-to-general cell-assembly architecture capable of generating specific perceptions and memories, as well as generalized knowledge and flexible actions. We show that this power-of-two-based permutation logic is widely used in cortical and subcortical circuits across animal species and is conserved for the processing of a variety of cognitive modalities including appetitive, emotional and social information...
2016: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/27893248/can-student-engagement-serve-as-a-motivational-resource-for-academic-coping-persistence-and-learning-during-late-elementary-and-early-middle-school
#18
Ellen A Skinner, Jennifer R Pitzer, Joel S Steele
How children and youth deal with academic challenges and setbacks can make a material difference to their learning and school success. Hence, it is important to investigate the factors that allow students to cope constructively. A process model focused on students' motivational resources was used to frame a study examining whether engagement in the classroom shapes students' academic coping, and whether coping in turn contributes to subsequent persistence on challenging tasks and learning, which then feed back into ongoing engagement...
December 2016: Developmental Psychology
https://www.readbyqxmd.com/read/27892727/information-deficits-and-second-opinion-seeking-a-survey-on-cancer-patients
#19
Tobias Fuchs, Hani Hanaya, Eckart Seilacher, Marie-Jolin Koester, Christian Keinki, Patrick Liebl, Jutta Huebner
OBJECTIVE: To learn more about cancer patients' motivation for seeking a second opinion. METHODS: Participants filled in a standardized questionnaire. RESULTS: Among 106 patients, 34% had looked for a second opinion, 81% wanted to check the accuracy of their treatment, and 49% needed to better understand the diagnosis. Low understanding of information was associated with looking for a second opinion, and 79% felt assured after a second opinion...
November 28, 2016: Cancer Investigation
https://www.readbyqxmd.com/read/27891217/models-of-eucalypt-phenology-predict-bat-population-flux
#20
John R Giles, Raina K Plowright, Peggy Eby, Alison J Peel, Hamish McCallum
Fruit bats (Pteropodidae) have received increased attention after the recent emergence of notable viral pathogens of bat origin. Their vagility hinders data collection on abundance and distribution, which constrains modeling efforts and our understanding of bat ecology, viral dynamics, and spillover. We addressed this knowledge gap with models and data on the occurrence and abundance of nectarivorous fruit bat populations at 3 day roosts in southeast Queensland. We used environmental drivers of nectar production as predictors and explored relationships between bat abundance and virus spillover...
October 2016: Ecology and Evolution
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