Tomoyuki Tsujikawa, Riichiro Nezu, Akira Andoh, Takao Saotome, Yoshio Araki, Yoshiyuki Ishizuka, Masaya Sasaki, Shigeki Koyama, Yoshihide Fujiyama
Acute lower gastrointestinal bleeding is a rare complication of Crohn's disease (CD). Although anti-tumor necrosis factor-alpha (TNF-alpha, infliximab) therapy has been established for patients with inflammatory and fistulous CD, there has been little evidence on whether infliximab is effective for the hemorrhagic type of CD. We report a case of a 31-year-old man with CD who had recurrent sudden-onset bloody stool. After a second surgery, he visited our hospital because of bloody stool. Infusion of infliximab stopped the bleeding and promoted the healing of ulcers in the ileum and ileocolon anastomosis...
2004: Journal of Gastroenterology