Letizia Senesi, Francesco De Francesco, Luca Farinelli, Sandra Manzotti, Giulio Gagliardi, Giuseppe Francesco Papalia, Michele Riccio, Antonio Gigante
Adipose-derived MSCs (ASCs) and stromal vascular fraction (SVF) play an important role in regenerative medicine and in the treatment of osteoarthritis. ASCs extracted from lipoaspirates are a valuable cell source due to their abundance and accessibility. ASCs are retrieved from the aqueous fraction of the digested lipoaspirate. The aqueous fraction is known as SVF and includes, ASCs, endothelial precursor cells (EPCs), endothelial cells (ECs), macrophages, smooth muscle cells, lymphocytes, pericytes, as well as pre-adipocytes...
2019: Frontiers in Cell and Developmental Biology