Olafur O Gudmundsson, G Bragi Walters, Andres Ingason, Stefan Johansson, Tetyana Zayats, Lavinia Athanasiu, Ida Elken Sonderby, Omar Gustafsson, Muhammad S Nawaz, Gudbjorn F Jonsson, Lina Jonsson, Per-Morten Knappskog, Ester Ingvarsdottir, Katrin Davidsdottir, Srdjan Djurovic, Gun Peggy Strømstad Knudsen, Ragna Bugge Askeland, Gyda S Haraldsdottir, Gisli Baldursson, Pall Magnusson, Engilbert Sigurdsson, Daniel F Gudbjartsson, Hreinn Stefansson, Ole A Andreassen, Jan Haavik, Ted Reichborn-Kjennerud, Kari Stefansson
Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable common childhood-onset neurodevelopmental disorder. Some rare copy number variations (CNVs) affect multiple neurodevelopmental disorders such as intellectual disability, autism spectrum disorders (ASD), schizophrenia and ADHD. The aim of this study is to determine to what extent ADHD shares high risk CNV alleles with schizophrenia and ASD. We compiled 19 neuropsychiatric CNVs and test 14, with sufficient power, for association with ADHD in Icelandic and Norwegian samples...
October 17, 2019: Translational Psychiatry