keyword
https://read.qxmd.com/read/36382982/bronchodilatateurs-chez-les-fumeurs-sans-bpco%C3%A2-une-fausse-bonne-id%C3%A3-e%C3%A2
#21
Gaétan Naudi
No abstract text is available yet for this article.
November 16, 2022: Revue Médicale Suisse
https://read.qxmd.com/read/36371331/-nurse-practitioners-as-key-actors-in-pulmonary-rehabilitation-for-chronic-obstructive-pulmonary-disease
#22
JOURNAL ARTICLE
G Fieutelot, S Valentin, B Ribeiro Baptista, A Chaouat, F Chabot, A Guillaumot
INTRODUCTION: While pulmonary rehabilitation is registered in the COPD management guidelines with a high level of evidence, it is not adequately performed in accordance with patients' needs. Advanced nurse practitioners (IPA, in French) provide expertise enabling improved access and enhanced implementation of rehabilitation programs. Based on foreign experience, the present study has been designed to propose avenues for the development of more effective practices in France. METHODS: Using Google Scholar and Pubmed databases, a search algorithm was used to identify international publications from 2003 to 2022 dealing with the role of nurse practitioners (IP, in French) in respiratory rehabilitation for COPD patients...
November 9, 2022: Revue des Maladies Respiratoires
https://read.qxmd.com/read/36170131/-copd-guidelines-for-primary-care-physicians
#23
JOURNAL ARTICLE
Mohammad Razban, Manuel Diego Sztajzel, Frédéric Lador, Johanna Sommer, Dagmar M Haller, Thierry Favrod-Coune
Chronic obstructive pulmonary disease (COPD) is common and should be suspected in any patient with chronic dyspnea, cough, or sputum with a history of exposure to tobacco or harmful particles. Spirometry is used for diagnosis. Full evaluation includes the severity of obstruction and clinical data, following the Global Initiative for Chronic Obstructive Lung Disease guidelines. Although the only treatments that have an impact on mortality are tobacco cessation, pulmonary rehabilitation and, for advanced disease, oxygen therapy, new symptomatic treatment have recently been made available...
September 28, 2022: Revue Médicale Suisse
https://read.qxmd.com/read/36115751/-inhaled-marijuana-and-the-lung-a-toxic-cocktail
#24
REVIEW
P Pradère, A M Ruppert, G Peiffer, J Perriot, M Adler, M Underner
Unlike the well-documented effects of tobacco smoke on the lung, the effects of cannabis smoke remain controversial, the main bias consisting in co-consumption of tobacco. That said, the composition of joint smoke is close to that of cigarettes, containing many compounds that are carcinogenic and/or alter the respiratory epithelium. Confirmed respiratory effects in chronic cannabis smokers include aggravated chronic bronchitis symptoms, a cumulative effect with tobacco on COPD and emphysema occurrence, an increased risk of bullous emphysema, and pneumothorax with heightened risk of recurrence after pleural symphysis...
October 2022: Revue des Maladies Respiratoires
https://read.qxmd.com/read/36108648/pulmonary-embolism-and-chronic-obstructive-pulmonary-disease
#25
JOURNAL ARTICLE
Laurent Bertoletti, Francis Couturaud, Olivier Sanchez, David Jimenez
Chronic obstructive pulmonary disease (COPD) is a frequent and devastating chronic respiratory disease. COPD is ranked among the top five causes of death worldwide. Patients with COPD suffer from persistent dyspnea, with periods of acute worsening, called exacerbations. Such exacerbations may be severe. In fact, one-third of COPD patients will be hospitalized because of an exacerbation. Hospitalization due to respiratory failure has been identified as a powerful predisposing risk factor for venous thromboembolism (VTE) for many years...
September 15, 2022: Seminars in Thrombosis and Hemostasis
https://read.qxmd.com/read/36081543/the-slow-path-to-therapeutic-adherence
#26
EDITORIAL
Francesco Ferrara, Livia Nava, Ugo Trama, Eduardo Nava, Antonio Vitiello
The therapeutic adherence to drug therapies is a crucial aspect for the proper management of chronicity. Over time, we are witnessing the evolution of the concept of adherence: today the patient must play an increasingly active role in the entire process in order for the pharmacological therapy to be fully successful. Poor therapeutic adherence can cause a bad success of the treatment path and, at the same time, lead to higher expenses. In this regard, it is necessary that each health company must undertake dedicated and organized paths...
October 2022: Hospital Pharmacy
https://read.qxmd.com/read/36057489/-is-helium-beneficial-in-a-pulmonary-rehabilitation-program-for-severe-copd
#27
JOURNAL ARTICLE
D Gindre, P Surpas, M T Garcia-Tejero, E Decullier, S Bin
Helium is known to reduce airflow limitation. Our hypothesis was that severe COPD patients undertaking exercise would show greater improvement in endurance under a heliox mixture (80/20%) than under air alone. This hypothesis was tested in a double-blinded, randomized study. METHODS: Out of the 53 patients included, 45 were randomly assigned to two groups : Heliox (n= 23) and Air (n= 22). Patients were assessed with spirometry under air and heliox, incremental exercise test, constant workload (80% Wmax) exercise test and weekly 6-minute walk test...
August 31, 2022: Revue des Maladies Respiratoires
https://read.qxmd.com/read/36055950/-copd-and-eosinophils
#28
REVIEW
M Gueçamburu, M Zysman
COPD is a major cause of morbidity and mortality worldwide. As research progresses, new patient phenotypes are being defined, providing hope for more personalized management of the disease. A significant proportion of patients present with an increased level of blood eosinophils, which may reflect bronchial eosinophilic inflammation. The aims of this article are to characterize the role of eosinophils in COPD in terms of pathophysiology, associated respiratory symptoms, impact on treatment and, finally, to consider different future treatment options...
August 30, 2022: Revue des Maladies Respiratoires
https://read.qxmd.com/read/36041937/-the-forced-oscillation-technique-in-the-functional-evaluation-of-copd-dyspnea
#29
JOURNAL ARTICLE
Arnaud Ghilain, Eric Marchand
INTRODUCTION: The goal of the present study is to assess the relationship between functional respiratory parameters measured by the forced oscillation technique (FOT) in COPD patients and (1) dyspnea; (2) inspiratory capacity (IC), along with the variations occurring subsequent to bronchodilation. METHODS: This cross-sectional study analyzed 40 stable COPD patients. Dyspnea was assessed by means of the San Diego Shortness of Breath Questionnaire. Forced oscillations were measured before and after bronchodilation by means of routine pulmonary function tests (PFTs)...
August 27, 2022: Revue des Maladies Respiratoires
https://read.qxmd.com/read/35715315/-alpha-1-antitrypsin-deficiency
#30
REVIEW
J-F Mornex
INTRODUCTION: Pulmonary emphysema and liver disease are the clinical expressions of alpha 1-antitrypsin deficiency, an autosomal recessive genetic disease. STATE OF THE ART: Alpha 1-antitrypsin deficiency is usually associated with the homozygous Z variant of the SERPINA1 gene. Its clinical expression always consists in a substantial reduction of alpha 1-antitrypsin serum concentration and its variants are analyzed by isoelectric focalization or molecular techniques...
October 2022: Revue des Maladies Respiratoires
https://read.qxmd.com/read/35599070/-first-copd-biennale-of-the-french-language-respiratory-society-2021-at-last
#31
EDITORIAL
G Deslée, M Zysman, J Gonzalez-Bermejo, N Roche
No abstract text is available yet for this article.
May 2022: Revue des Maladies Respiratoires
https://read.qxmd.com/read/35568574/-take-home-messages-from-the-copd-2021-biennial-of-the-french-society-of-respiratory-diseases-understanding-to-so-as-to-better-innovate
#32
REVIEW
J Ancel, M Guecamburu, V Marques Da Silva, P Schilfarth, L Boyer, C Pilette, C Martin, P Devillier, P Berger, M Zysman, O Le Rouzic, J Gonzalez-Bermejo, B Degano, P-R Burgel, E Ahmed, N Roche, G Deslee
INTRODUCTION: The first COPD biennial organized by the French Society of Respiratory Diseases (SPLF) took place on 17 December 2021. STATE OF THE ART: The objective of the biennial was to discuss current knowledge regarding COPD pathophysiology, current treatments, research development, and future therapeutic approaches. PERSPECTIVES: The different lecturers laid emphasis on the complexity of pathophysiologic mechanisms including bronchial, bronchiolar and parenchymal alterations, and also dwelt on the role of microbiota composition in COPD pathenogenesis...
May 11, 2022: Revue des Maladies Respiratoires
https://read.qxmd.com/read/35389009/-fixed-combination-of-budesonide-formoterol-glycopyrronium-for-the-treatment-of-severe-copd-trixeo-aerosphere%C3%A2
#33
JOURNAL ARTICLE
R Louis, O Bonhomme, V Heinen, D Nguyen, H Van Cauwenberge, J L Corhay
Here we present pharmacological and clinical properties of a new fixed triple inhaled combination including an inhaled corticoid, a long acting ?2 agonist and a long acting anticholinergic for the treatment of severe chronic obstructive pulmonary disease (COPD). Trixeo Aerosphere® is the name of this triple combination which contains 160 µg budesonide, 4,8 µg formoterol and 9 µg glycopyrronium delivered by a pMDI. As compared to a budesonide/formoterol combination, Trixeo Aerosphere® improves forced expiratory volume in the first second (FEV1)...
April 2022: Revue Médicale de Liège
https://read.qxmd.com/read/35144842/-active-mind-body-movement-therapies-and-pulmonary-rehabilitation-for-people-with-copd
#34
REVIEW
R Gauthier, J Vassail, J-P Croutaz, C Raspaud
INTRODUCTION: Active body-mind movement therapies are performed with the aim of engaging the person in taking care of their health. They are represented by Qi gong, Tai Chi and yoga. They all include postures, breathing exercises and meditation. When utilized together with traditional medicine, they allow a more holistic view of the patient, thereby facilitating improved quality of life. STATE OF THE ART: While these therapies have been studied in cases of chronic obstructive pulmonary disease, and compared to routine care or walking-type physical activity, they have seldom been studied in the context of respiratory rehabilitation, even though their effects on quality of life and functional capacity are clinically significant, while some comorbidities may likewise be positively impacted...
March 2022: Revue des Maladies Respiratoires
https://read.qxmd.com/read/35000811/-respiratory-telerehabilitation-in-cases-of-copd
#35
REVIEW
M Hayot, D Saey, F Costes, F Bughin, A Chambellan
Telerehabilitation brings together a set of rehabilitation practices applied remotely by means of information and communication technologies. Even though it has been taking on increasing importance in many health fields over 10 years, telerehabilitation had yet to find its place in pulmonary rehabilitation before 2020, when the pandemic situation impelled numerous teams to put it to work. Pilot studies on respiratory diseases, primarily COPD, along with recent data from randomized or non-randomized studies, have enhanced our understanding of "remote" practice...
February 2022: Revue des Maladies Respiratoires
https://read.qxmd.com/read/34962717/large-scale-plasma-proteomics-can-reveal-distinct-endotypes-in-chronic-obstructive-pulmonary-disease-and-severe-asthma
#36
JOURNAL ARTICLE
Masaru Suzuki, John J Cole, Satoshi Konno, Hironi Makita, Hiroki Kimura, Masaharu Nishimura, Rose A Maciewicz
BACKGROUND: Chronic airway diseases including chronic obstructive pulmonary disease (COPD) and asthma are heterogenous in nature and endotypes within are underpinned by complex biology. This study aimed to investigate the utility of proteomic profiling of plasma combined with bioinformatic mining, and to define molecular endotypes and expand our knowledge of the underlying biology in chronic respiratory diseases. METHODS: The plasma proteome was evaluated using an aptamer-based affinity proteomics platform (SOMAscan®), representing 1238 proteins in 34 subjects with stable COPD and 51 subjects with stable but severe asthma...
December 2021: Clinical and Translational Allergy
https://read.qxmd.com/read/34814728/palliative-care-for-patients-with-advanced-copd-in-primary-care
#37
JOURNAL ARTICLE
Tanja Fusi-Schmidhauser
<b/> Patients with advanced COPD have a high symptom burden that is often multidimensional. Identification of patients who might benefit from palliative care through validated identification tools, multidimensional symptom management, and timely discussion of advance planning are elements of a palliative care approach for these patients and their families. Coordination among stakeholders providing care and support to these patients is central to ensuring high-quality care and meeting all of their needs...
November 2021: Praxis
https://read.qxmd.com/read/34783318/-the-family-and-community-nurse-led-proactive-management-of-copd-patients-experience-of-an-italian-health-district
#38
JOURNAL ARTICLE
Sabrina Ranzani, Marco Dalmasso, Patrizia Gioia, Laura Buttera, Luisella Audisio, Paola Fasano, Silvio Venuti, Carlo Mamo
. The family and community nurse-led proactive management of COPD patients: experience of an Italian health district. INTRODUCTION: Integrated care management for COPD may reduce healthcare utilisation, improving cost-efficiency. AIM: To assess the primary outcomes of a family and community nurse-led proactive management of COPD patients of an Italian health district. METHODS: Target population comprised men and women >60 years, resident in the municipalities of Collegno and Grugliasco (metropolitan area of Turin)...
July 2021: Assistenza Infermieristica e Ricerca: AIR
https://read.qxmd.com/read/34774369/-identifying-the-barriers-to-pulmonary-rehabilitation-for-patients-with-copd
#39
JOURNAL ARTICLE
F Cachau, A Masson, P Di Patrizio
INTRODUCTION: Although pulmonary rehabilitation is a core treatment for chronic obstructive pulmonary disease (COPD) approved by the French National Authority for Health, there is no doubt that it is insufficiently used in France. Pulmonary rehabilitation consists of exercise training and patient education delivered in a multidisciplinary programme of care to reverse the downward spiral of deconditioning caused by the illness as well as improving patients' ability to self-manage. The aim of this study was to identify the obstacles that prevent the delivery of pulmonary rehabilitation, so as to understand its lack of use...
November 10, 2021: Revue des Maladies Respiratoires
https://read.qxmd.com/read/34702052/-type-2-asthma-leaving-behind-the-perspective-of-the-seventies
#40
JOURNAL ARTICLE
Thomas Rothe, Tsogyal Daniela Latshang
Type-2 Asthma: Leaving Behind the Perspective of the Seventies Abstract. The diagnosis 'bronchial asthma' spans different phenotypes of this disease like an umbrella. The differentiation of these phenotypes and their overlaps is becoming increasingly important, as the phenotype-specific treatment approaches of today are not effective with every form of asthma. These approaches include the strategy of allergen avoidance, allergen immunotherapy and, most importantly, the newly available biologics for asthma. Treatable disease patterns, so-called 'treatable traits', require targeted diagnostics...
2021: Praxis
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