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https://www.readbyqxmd.com/read/28092847/repetitive-transcranial-magnetic-stimulation-for-the-treatment-of-post-stroke-depression-a-systematic-review-and-meta-analysis-of-randomized-controlled-clinical-trials
#1
REVIEW
XinYi Shen, MingYi Liu, Yu Cheng, Cui Jia, XinYue Pan, QingYun Gou, XinLian Liu, Hui Cao, LuShun Zhang
BACKGROUND: Every year, more than fifteen million people worldwide experience a stroke, nearly 30% of stroke survivors are likely to experience post-stroke depression (PSD). Repetitive transcranial magnetic stimulation (rTMS) is one of the emerging techniques which assist in targeting rehabilitation after stroke. Although deterioration of PSD greatly affects the recovery and quality of life of stroke sufferers, the effect of rTMS therapy has not been systematically studied. OBJECTIVE: A systematic review and meta-analysis was conducted to determine the effect of rTMS on PSD...
January 10, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28092754/public-participation-gis-for-improving-wood-burning-emissions-from-residential-heating-and-urban-environmental-management
#2
Susana López-Aparicio, Matthias Vogt, Philipp Schneider, Maarit Kahila-Tani, Anna Broberg
A crowdsourcing study supported by a public participation GIS tool was designed and carried out in two Norwegian regions. The aim was to improve the knowledge about emissions from wood burning for residential heating in urban areas based on the collection of citizens' localized insights. We focus on three main issues: 1) type of dwelling and residential heating source; 2) wood consumption and type of wood appliances; and 3) citizens' perception of the urban environment. Our study shows the importance of wood burning for residential heating, and of the resulted particle emissions, in Norwegian urban areas...
January 13, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28092712/-global-bioethics-and-biocultural-ethics
#3
Ricardo Rozzi
The biocultural ethic recovers an understanding of the vital links between the life habits of the coinhabitants (humans and other-than-human) that share a habitat. The ″3Hs″ formal framework of the biocultural ethics provides a conceptual and methodological tool to understand and to better manage complex eco-social or biocultural systems in heterogeneous regions of the planet. From the global bioethics originally proposed by V.R. Potter, the integration of theory and praxis promoted by Alfredo Pradenas in the Bioethics Society of Chile, and the conceptual framework of biocultural ethics (including traditions of philosophical thought, scientific and Amerindians), I develop a comparative analysis of: 1...
September 2016: Cuadernos de Bioética: Revista Oficial de la Asociación Española de Bioética y Ética Médica
https://www.readbyqxmd.com/read/28092582/automatic-prediction-of-health-status-using-smartphone-derived-behaviour-profiles
#4
Daniel Kelly, Kevin Curran, Brian Caulfield
OBJECTIVE: Current methods of assessing the affect a patients' health has on their daily life are extremely limited. The aim of this work is to develop a sensor based approach to health status measurement in order to objectively measure health status. METHODS: Techniques to generate human behaviour profiles, derived from smartphone accelerometer and gyroscope sensors, are proposed. Experiments, using SVM regression models, are then conducted in order to evaluate the use of the proposed behaviour profiles as a predictor of health status...
January 9, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28092457/insulin-sensitivity-and-inflammation-mediate-the-impact-of-fitness-on-cerebrovascular-health-in-adolescents
#5
Po Lai Yau, Naima Ross, Andrew Tirsi, Arslan Arif, Zeynep Ozinci, Antonio Convit
BACKGROUND/OBJECTIVES: To investigate in adolescents the relationships between retinal vessel diameter, physical fitness, insulin sensitivity, and systemic inflammation. METHODS: We evaluated 157 adolescents, 112 with excessive weight and 45 lean, all without type 2 diabetes mellitus. All received detailed evaluations, including measurements of retinal vessel diameter, insulin sensitivity, levels of inflammation, and physical fitness. RESULTS: Overweight/obese adolescents had significantly narrower retinal arteriolar and wider venular diameters, significantly lower insulin sensitivity, and physical fitness...
January 16, 2017: Childhood Obesity
https://www.readbyqxmd.com/read/28092296/qualitative-analysis-of-parental-observations-on-quality-of-life-in-australian-children-with-down-syndrome
#6
Nada Murphy, Amy Epstein, Helen Leonard, Elise Davis, Dinah Reddihough, Andrew Whitehouse, Peter Jacoby, Jenny Bourke, Katrina Williams, Jenny Downs
OBJECTIVE: There are many challenges to health, functioning, and participation for children with Down syndrome; yet, the quality-of-life (QOL) domains important for this group have never been clearly articulated. This study investigated parental observations to identify QOL domains in children with Down syndrome and determined whether domains differed between children and adolescents. METHODS: The sample comprised 17 families whose child with Down syndrome was aged 6 to 18 years...
January 12, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28092295/income-family-context-and-self-regulation-in-5-year-old-children
#7
Mengying Li, Jenna L Riis, Sharon R Ghazarian, Sara B Johnson
OBJECTIVE: Self-regulation (SR) is a core aspect of child development with enduring effects on health and wellbeing across the lifespan. Early childhood poverty may shape SR development. This study examined the cross-sectional relationship among family income, family context, and SR in 5-year-old children. METHODS: A total of 140 five-year-old children and their mothers participated in the study. Children completed a battery of SR tasks; mothers completed questionnaires...
January 12, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28092210/the-insights-of-health-and-welfare-professionals-on-hurdles-that-impede-economic-evaluations-of-welfare-interventions
#8
J Schepers, J Plaete, I De Bourdeaudhuij, L Annemans, S Simoens
OBJECTIVES: Four hurdles associated with economic evaluations in welfare interventions were identified and discussed in a previous published literature review. These hurdles include (i) 'Ignoring the impact of condition-specific outcomes', (ii) 'Ignoring the impact of QoL externalities', (iii) 'Calculation of costs from a too narrow perspective' and (iv) 'The lack of well-described & standardized interventions'. This study aims to determine how healthcare providers and social workers experience and deal with these hurdles in practice and what solutions or new insights they would suggest...
January 16, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/28092207/healthcare-burden-of-depression-in-adults-with-arthritis
#9
Usha Sambamoorthi, Drishti Shah, Xiaohui Zhao
Arthritis and depression are two of the top disabling conditions. When arthritis and depression exist in the same individual, they can interact with each other negatively and pose a significant healthcare burden on the patients, their families, payers, healthcare systems, and society as a whole. Areas covered: The primary objective of this review is to summarize, identify knowledge gaps and discuss the challenges in estimating the healthcare burden of depression among individuals with arthritis. Electronic literature searches were performed on PubMed, Embase, EBSCOhost, Scopus, the Cochrane Library, and Google Scholar to identify relevant studies...
January 16, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/28092171/a-pangenotypic-single-tablet-regimen-of-sofosbuvir-velpatasvir-for-the-treatment-of-chronic-hepatitis-c-infection
#10
Ilan S Weisberg, Ira M Jacobson
Hepatitis C virus (HCV) infects nearly 170 million people worldwide and is a leading cause of progressive liver damage, cirrhosis, and hepatocellular carcinoma. Curative therapies have historically relied on interferon-based treatments and were limited by significant toxicity and poor response rates, particularly among patients with prior treatment failure and advanced hepatic fibrosis. The recent advent of direct acting antiviral (DAA) agents which target key steps in the HCV viral life cycle has transformed the landscape of HCV treatment by offering highly effective and well tolerated interferon-free treatments...
January 16, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28092150/issues-in-nutrition-dietary-supplements
#11
Margaret E Thompson, Mary Barth Noel
The majority of American adults report use of one or more dietary supplements every day or occasionally. The Dietary Supplement Health and Education Act of 1994 defines dietary supplements and regulates their manufacture and distribution. One of the most commonly used supplements is vitamin D. Measurement of serum levels of vitamin D must be undertaken with the caveats that different laboratories define normal levels differently, and that there is rarely a clinical correlation with the actual level. Patients should understand that supplements should not be used to excess, as there are toxicities and other adverse effects associated with most of them...
January 2017: FP Essentials
https://www.readbyqxmd.com/read/28092018/bladder-dysfunction-in-multiple-sclerosis-a-6-year-follow-up-study
#12
Darija Kisic Tepavcevic, Tatjana Pekmezovic, Irena Dujmovic Basuroski, Sarlota Mesaros, Jelena Drulovic
Bladder dysfunction (BD) is the most common autonomic disturbance in multiple sclerosis, but often overlooked and undertreated. The purpose of this longitudinal study was to explore the changes in the frequency of BD symptoms in MS cohort after a period of 3 and 6 years of follow-up, as well as to investigate the correlations between the presence of BD symptoms and both clinical characteristics and the health-related quality of life (HRQoL) at each subsequent point of estimation. The study population comprises a cohort of 93 patients with MS (McDonald's criteria, 2001)...
January 13, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/28091969/quality-of-life-as-predictor-for-the-development-of-cardiac-ischemia-in-high-risk-asymptomatic-diabetic-patients
#13
Philip Haaf, Myriam Ritter, Leticia Grize, Matthias E Pfisterer, Michael J Zellweger
BACKGROUND: Ischemia induced by psychological stress and depression is a common phenomenon in stable coronary artery disease (CAD). We evaluated the quality of life (QoL) of diabetic patients screened for CAD and assessed the prognostic value of mental and physical QoL scores to predict the development of new cardiac ischemia. METHODS: Prospective multicentre outcome study. The study comprised 400 asymptomatic diabetic patients without history or symptoms of CAD...
January 13, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28091679/sustainability-of-renewable-fuel-infrastructure-a-screening-lca-case-study-of-anticorrosive-graphene-oxide-epoxy-liners-in-steel-tanks-for-the-storage-of-biodiesel-and-its-blends
#14
Govinda Chilkoor, Venkata K K Upadhyayula, Venkataramana Gadhamshetty, Nikhil Koratkar, Mats Tysklind
Biodiesel is a widely used fuel that meets the renewable fuel standards developed under the Energy Policy Act of 2005. However, biodiesel is known to pose a series of abiotic and biotic corrosion risks to storage tanks. A typical practice (incumbent system) used to protect the tanks from these risks include (i) coating the interior surface of the tank with a solvent-free epoxy (SFE) liner, and (ii) adding a biocide to the tank. Herein, we present a screening-level life-cycle assessment study to compare the environmental performance of a graphene oxide (GO)-epoxy (GOE) liner with the incumbent system...
January 16, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28091604/polyglucose-nanoparticles-with-renal-elimination-and-macrophage-avidity-facilitate-pet-imaging-in-ischaemic-heart-disease
#15
Edmund J Keliher, Yu-Xiang Ye, Gregory R Wojtkiewicz, Aaron D Aguirre, Benoit Tricot, Max L Senders, Hannah Groenen, Francois Fay, Carlos Perez-Medina, Claudia Calcagno, Giuseppe Carlucci, Thomas Reiner, Yuan Sun, Gabriel Courties, Yoshiko Iwamoto, Hye-Yeong Kim, Cuihua Wang, John W Chen, Filip K Swirski, Hsiao-Ying Wey, Jacob Hooker, Zahi A Fayad, Willem J M Mulder, Ralph Weissleder, Matthias Nahrendorf
Tissue macrophage numbers vary during health versus disease. Abundant inflammatory macrophages destruct tissues, leading to atherosclerosis, myocardial infarction and heart failure. Emerging therapeutic options create interest in monitoring macrophages in patients. Here we describe positron emission tomography (PET) imaging with (18)F-Macroflor, a modified polyglucose nanoparticle with high avidity for macrophages. Due to its small size, Macroflor is excreted renally, a prerequisite for imaging with the isotope flourine-18...
January 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/28091431/determinants-of-quality-of-life-among-community-dwelling-persons-with-spinal-cord-injury-a-path-analysis
#16
End Ekechukwu, J O Ikrechero, A O Ezeukwu, A V Egwuonwu, L Umar, U M Badaru
CONTEXT: Recent advancement in technology and medical care has resulted in an increase not only in disability arising from spinal cord injury (SCI) but also its attendant challenges such as poor quality of life (QoL). AIM: To test a theoretical model of predictors of QoL among persons with SCI. SETTINGS AND DESIGN: Study was conducted in the South Eastern Nigeria. A longitudinal study design was employed. MATERIALS AND METHODS: A total of 64 persons with SCI discharged from in-hospital admission participated in this study...
February 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28091355/a-systematic-review-evaluating-the-impact-of-paid-home-carer-training-supervision-and-other-interventions-on-the-health-and-well-being-of-older-home-care-clients
#17
Claudia Cooper, Blerta Cenko, Briony Dow, Penny Rapaport
BACKGROUND: Interventions to support and skill paid home carers and managers could potentially improve health and well-being of older home care clients. This is the first systematic review of interventions to improve how home carers and home care agencies deliver care to older people, with regard to clients' health and well-being and paid carers' well-being, job satisfaction, and retention. METHODS: We reviewed 10/731 papers found in the electronic search (to January 2016) fitting predetermined criteria, assessed quality using a checklist, and synthesized data using quantitative and qualitative techniques...
January 16, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28090819/toxoplasmic-encephalitis-relapse-rates-with-pyrimethamine-based-therapy-systematic-review-and-meta-analysis
#18
Mark P Connolly, Elizabeth Goodwin, Carina Schey, Jacqueline Zummo
Toxoplasmic encephalitis (TE) is caused by Toxoplasma gondii infection and can be a life-threatening disease in immunocompromised patients. This study evaluated the rate of relapse associated with pyrimethamine-based maintenance therapy (i.e. secondary prophylaxis) in patients with human immunodeficiency virus (HIV) or AIDs treated prior to and after the common use (i.e. 1996) of highly active antiretroviral therapy (HAART) (pre-HAART and post-HAART, respectively). PubMed, Google Scholar, and Cochrane databases were searched to 6 June 2016 using search terms: pyrimethamine, Daraprim, Fansidar, Metakelfin, Fansimef, 5-(4-chlorophenyl)-6-ethyl-2,4-pyrimidinediamine, encephalitis, cerebral, toxoplasmosis, toxoplasmic, and gondii...
January 16, 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28090750/professionals-views-on-mental-health-service-users-education-challenges-and-support
#19
I Nieminen, M Kaunonen
: WHAT IS KNOWN ON THE SUBJECT?: Mental health service users (MHSUs) may experience disruptions in their education. However, education has been shown to have a positive influence on their recovery, potentially offering them broader employment opportunities. The literature suggests that providing support for MHSUs in their educational efforts may be beneficial and is wished for by the service users themselves. However, there is a lack of mental health professionals' views on the topic in the setting of a community mental health centre...
February 2017: Journal of Psychiatric and Mental Health Nursing
https://www.readbyqxmd.com/read/28090704/effectiveness-of-telephone-based-interventions-on-health-related-quality-of-life-and-prognostic-outcomes-in-breast-cancer-patients-and-survivors-a-meta-analysis
#20
REVIEW
Q Zhang, L Zhang, R Yin, T Fu, H Chen, B Shen
The aim of this meta-analysis was to evaluate the effect of telephone-based interventions on prognostic outcomes and health-related quality of life (HRQoL) in breast cancer patients and survivors. A systematic search of the Cochrane Library, Web of science, Medline, EMBASE, CNKI and CBM database was carried out. Randomised, controlled trials (RCTs) examining the effects of telephone-based intervention versus a control group receiving no telephone intervention, on prognostic outcomes and HRQoL with breast cancer were included...
January 16, 2017: European Journal of Cancer Care
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