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https://www.readbyqxmd.com/read/29157453/computer-aided-tumor-diagnosis-in-3-d-breast-elastography
#1
Yao-Sian Huang, Etsuo Takada, Sachiyo Konno, Chiun-Shen Huang, Ming-Hao Kuo, Ruey-Feng Chang
BACKGROUND AND OBJECTIVE: Breast cancer is the major cause of cancer-related mortality in women. However, the death rate can be effectively decreased if the breast cancer can be detected early and treated appropriately. In recent years, many studies have indicated that the elastography has the better diagnosis performance than conventional ultrasound (US). METHOD: In this study, the 3-D tumor contour is obtained by using the proposed segmentation methods and then the features containing texture information, shape information, ellipsoid fitting information are extracted respectively by using the segmented 3-D tumor contour and B-mode images, and the features containing elasticity information are calculated using the same contour and elastographic images...
January 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29152563/integrated-radiomic-framework-for-breast-cancer-and-tumor-biology-using-advanced-machine-learning-and-multiparametric-mri
#2
Vishwa S Parekh, Michael A Jacobs
Radiomics deals with the high throughput extraction of quantitative textural information from radiological images that not visually perceivable by radiologists. However, the biological correlation between radiomic features and different tissues of interest has not been established. To that end, we present the radiomic feature mapping framework to generate radiomic MRI texture image representations called the radiomic feature maps (RFM) and correlate the RFMs with quantitative texture values, breast tissue biology using quantitative MRI and classify benign from malignant tumors...
2017: NPJ Breast Cancer
https://www.readbyqxmd.com/read/29140606/mr-textural-analysis-on-t2-flair-images-for-the-prediction-of-true-oligodendroglioma-by-the-2016-who-genetic-classification
#3
Wenting Rui, Yan Ren, Yin Wang, Xinyi Gao, Xiao Xu, Zhenwei Yao
BACKGROUND: The genetic status of 1p/19q is important for differentiating oligodendroglioma, isocitrate-dehydrogenase (IDH)-mutant, and 1p/19q-codeleted from diffuse astrocytoma, IDH-mutant according to the 2016 World Health Organization (WHO) criteria. PURPOSE: To assess the value of magnetic resonance textural analysis (MRTA) on T2 fluid-attenuated inversion recovery (FLAIR) images for making a genetically integrated diagnosis of true oligodendroglioma by WHO guidelines...
November 15, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29140113/prediction-of-pancreatic-neuroendocrine-tumor-grade-based-on-ct-features-and-texture-analysis
#4
Rodrigo Canellas, Kristine S Burk, Anushri Parakh, Dushyant V Sahani
OBJECTIVE: The purposes of this study were to assess whether CT texture analysis and CT features are predictive of pancreatic neuroendocrine tumor (PNET) grade based on the World Health Organization (WHO) classification and to identify features related to disease progression after surgery. MATERIALS AND METHODS: Preoperative contrast-enhanced CT images of 101 patients with PNETs were assessed. The images were evaluated for tumor location, tumor size, tumor pattern, predominantly solid or cystic composition, presence of calcification, presence of heterogeneous enhancement on contrast-enhanced images, presence of pancreatic duct dilatation, presence of pancreatic atrophy, presence of vascular involvement by the tumor, and presence of lymphadenopathy...
November 15, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29134348/machine-learning-based-quantitative-texture-analysis-of-ct-images-of-small-renal-masses-differentiation-of-angiomyolipoma-without-visible-fat-from-renal-cell-carcinoma
#5
Zhichao Feng, Pengfei Rong, Peng Cao, Qingyu Zhou, Wenwei Zhu, Zhimin Yan, Qianyun Liu, Wei Wang
OBJECTIVE: To evaluate the diagnostic performance of machine-learning based quantitative texture analysis of CT images to differentiate small (≤ 4 cm) angiomyolipoma without visible fat (AMLwvf) from renal cell carcinoma (RCC). METHODS: This single-institutional retrospective study included 58 patients with pathologically proven small renal mass (17 in AMLwvf and 41 in RCC groups). Texture features were extracted from the largest possible tumorous regions of interest (ROIs) by manual segmentation in preoperative three-phase CT images...
November 13, 2017: European Radiology
https://www.readbyqxmd.com/read/29134191/assessing-treatment-response-in-triple-negative-breast-cancer-from-quantitative-image-analysis-in-perfusion-magnetic-resonance-imaging
#6
Imon Banerjee, Sadhika Malladi, Daniela Lee, Adrien Depeursinge, Melinda Telli, Jafi Lipson, Daniel Golden, Daniel L Rubin
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is sensitive but not specific to determining treatment response in early stage triple-negative breast cancer (TNBC) patients. We propose an efficient computerized technique for assessing treatment response, specifically the residual tumor (RT) status and pathological complete response (pCR), in response to neoadjuvant chemotherapy. The proposed approach is based on Riesz wavelet analysis of pharmacokinetic maps derived from noninvasive DCE-MRI scans, obtained before and after treatment...
January 2018: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29120034/ultrasonographic-features-of-eccrine-spiradenoma
#7
Cheol Mog Hwang, Byeong Seong Kang, Hyeok Jin Hong, Joo Yeon Lee, Jae Hee Suh, Eun Mee Han, In Hye Song, Hyun Seok Shim, Sang Hoon Lee
The purpose of this series was to evaluate the features of eccrine spiradenoma on ultrasonography (US). We reviewed the clinical data of 8 patients with eccrine spiradenoma who underwent preoperative US at 4 different medical institutions from 2004 to 2016 and analyzed the US features in terms of the tumor location, size, shape, margin, echo texture, echogenicity, posterior acoustic enhancement, calcification, septum, and color Doppler flow. There were 7 female patients and 1 male patient. The mean patient age was 45...
November 9, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29119525/haralick-s-texture-features-for-the-prediction-of-response-to-therapy-in-colorectal-cancer-a-preliminary-study
#8
Damiano Caruso, Marta Zerunian, Maria Ciolina, Domenico de Santis, Marco Rengo, Mumtaz H Soomro, Gaetano Giunta, Silvia Conforto, Maurizio Schmid, Emanuele Neri, Andrea Laghi
PURPOSE: Haralick features Texture analysis is a recent oncologic imaging biomarker used to assess quantitatively the heterogeneity within a tumor. The aim of this study is to evaluate which Haralick's features are the most feasible in predicting tumor response to neoadjuvant chemoradiotherapy (CRT) in colorectal cancer. MATERIALS AND METHODS: After MRI and histological assessment, eight patients were enrolled and divided into two groups based on response to neoadjuvant CRT in complete responders (CR) and non-responders (NR)...
November 8, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/29097912/automated-generation-of-reliable-blood-velocity-parameter-maps-from-contrast-enhanced-ultrasound-data
#9
Benjamin Theek, Tatjana Opacic, Diana Möckel, Georg Schmitz, Twan Lammers, Fabian Kiessling
Objectives: The purpose of this study was the automated generation and validation of parametric blood flow velocity maps, based on contrast-enhanced ultrasound (CEUS) scans. Materials and Methods: Ethical approval for animal experiments was obtained. CEUS destruction-replenishment sequences were recorded in phantoms and three different tumor xenograft mouse models. Systematic pixel binning and intensity averaging was performed to generate parameter maps of blood flow velocities with different pixel resolution...
2017: Contrast Media & Molecular Imaging
https://www.readbyqxmd.com/read/29092946/a-containerized-software-system-for-generation-management-and-exploration-of-features-from-whole-slide-tissue-images
#10
Joel Saltz, Ashish Sharma, Ganesh Iyer, Erich Bremer, Feiqiao Wang, Alina Jasniewski, Tammy DiPrima, Jonas S Almeida, Yi Gao, Tianhao Zhao, Mary Saltz, Tahsin Kurc
Well-curated sets of pathology image features will be critical to clinical studies that aim to evaluate and predict treatment responses. Researchers require information synthesized across multiple biological scales, from the patient to the molecular scale, to more effectively study cancer. This article describes a suite of services and web applications that allow users to select regions of interest in whole slide tissue images, run a segmentation pipeline on the selected regions to extract nuclei and compute shape, size, intensity, and texture features, store and index images and analysis results, and visualize and explore images and computed features...
November 1, 2017: Cancer Research
https://www.readbyqxmd.com/read/29059949/application-of-mri-texture-analysis-in-the-study-of-the-posterior-fossa-tumors-growing-trend-in-children
#11
Mengmeng Li, Zhigang Shang, Yonghui Dong, Yong Zhang, Ya Li
In order to analyze the growing trend of the posterior fossa tumor in children and provide assistant basis for the treatment or surgery of tumors, a variety of texture analysis methods were comprehensive used to analyze and identify three kinds of brain tissues, tumor region, tumor diffusion region and normal brain tissue region. The MRIs of tumor patients were collected to extract texture features. Then feature selection method CFS and feature compression method partial least squares regression (PLSR) were used to process these feature space...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29057333/a-magnetic-resonance-imaging-based-approach-to-quantify-radiation-induced-normal-tissue-injuries-applied-to-trismus-in-head-and-neck-cancer
#12
Maria Thor, Neelam Tyagi, Vaios Hatzoglou, Aditya Apte, Ziad Saleh, Nadeem Riaz, Nancy Y Lee, Joseph O Deasy
BACKGROUND AND PURPOSE: In this study we investigated the ability of textures from T1-weighted MRI scans post-contrast (T1wpost) to identify the critical muscle(s) for radiation-induced trismus. MATERIALS AND METHODS: The study included ten cases (Trismus: ≥Grade 1), and ten age-sex-tumor-location-and-stage-matched controls treated with intensity-modulated radiotherapy to 70Gy@2.12Gy in 2005-2009. Trismus status and T1wPost were conducted within one year post-radiotherapy...
January 2017: Phys Imaging Radiat Oncol
https://www.readbyqxmd.com/read/29056023/-effects-of-improved-v-y-advancement-flap-with-major-artery-perforator-on-repairing-skin-and-soft-tissue-defects
#13
S T Zhou, M T Huang, J Z Zeng, P F Liang, M H Zhang
Objective: To explore the effect of improved V-Y advancement flap with major artery perforator on repairing several skin and soft tissue defects in whole body. Methods: From March 2015 to June 2017, 4 cases with pressure ulcer in sacrococcygeal region, 4 cases with pressure ulcer at ischial tuberosity, 2 cases with scalp and skull defects at occiput, 1 case with secondary wound after tumor resection in axillary region, and 2 cases with skin and soft tissue defects caused by other trauma were hospitalized, with disease duration ranging from 1 week to 6 months...
October 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29051791/hyalinizing-trabecular-tumor-of-the-thyroid-gland-and-its-significant-diagnostic-issue
#14
Dustin J Jones, Christopher R Kieliszak, Sanjay S Patel, Christopher R Selinsky
BACKGROUND: Hyalinizing trabecular tumors (HTT) are rare follicular cell-derived tumors of the thyroid gland that are infrequently reported in otolaryngology literature. We present here an interesting case of HTT which provides the basis for review of this entity's clinical characteristics, criteria useful in making the diagnosis, and any currently available therapeutic modalities. CASE PRESENTATION: A 70-year-old Caucasian female underwent a CT scan of her chest and was incidentally found to have a nodule within the right thyroid lobe...
2017: Thyroid Research
https://www.readbyqxmd.com/read/29051570/prediction-of-recurrence-in-early-stage-non-small-cell-lung-cancer-using-computer-extracted-nuclear-features-from-digital-h-e-images
#15
Xiangxue Wang, Andrew Janowczyk, Yu Zhou, Rajat Thawani, Pingfu Fu, Kurt Schalper, Vamsidhar Velcheti, Anant Madabhushi
Identification of patients with early stage non-small cell lung cancer (NSCLC) with high risk of recurrence could help identify patients who would receive additional benefit from adjuvant therapy. In this work, we present a computational histomorphometric image classifier using nuclear orientation, texture, shape, and tumor architecture to predict disease recurrence in early stage NSCLC from digitized H&E tissue microarray (TMA) slides. Using a retrospective cohort of early stage NSCLC patients (Cohort #1, n = 70), we constructed a supervised classification model involving the most predictive features associated with disease recurrence...
October 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29046927/fdg-pet-ct-radiomics-for-predicting-the-outcome-of-locally-advanced-rectal-cancer
#16
Pierre Lovinfosse, Marc Polus, Daniel Van Daele, Philippe Martinive, Frédéric Daenen, Mathieu Hatt, Dimitris Visvikis, Benjamin Koopmansch, Frédéric Lambert, Carla Coimbra, Laurence Seidel, Adelin Albert, Philippe Delvenne, Roland Hustinx
PURPOSE: The aim of this study was to investigate the prognostic value of baseline (18)F-FDG PET/CT textural analysis in locally-advanced rectal cancer (LARC). METHODS: Eighty-six patients with LARC underwent (18)F-FDG PET/CT before treatment. Maximum and mean standard uptake values (SUVmax and SUVmean), metabolic tumoral volume (MTV), total lesion glycolysis (TLG), histogram-intensity features, as well as 11 local and regional textural features, were evaluated...
October 18, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29042619/diffusion-tensor-image-features-predict-idh-genotype-in-newly-diagnosed-who-grade-ii-iii-gliomas
#17
Paul Eichinger, Esther Alberts, Claire Delbridge, Stefano Trebeschi, Alexander Valentinitsch, Stefanie Bette, Thomas Huber, Jens Gempt, Bernhard Meyer, Juergen Schlegel, Claus Zimmer, Jan S Kirschke, Bjoern H Menze, Benedikt Wiestler
We hypothesized that machine learning analysis based on texture information from the preoperative MRI can predict IDH mutational status in newly diagnosed WHO grade II and III gliomas. This retrospective study included in total 79 consecutive patients with a newly diagnosed WHO grade II or III glioma. Local binary pattern texture features were generated from preoperative B0 and fractional anisotropy (FA) diffusion tensor imaging. Using a training set of 59 patients, a single hidden layer neural network was then trained on the texture features to predict IDH status...
October 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29036692/clinical-utility-of-texture-analysis-of-18f-fdg-pet-ct-in-patients-with-stage-i-lung-cancer-treated-with-stereotactic-body-radiotherapy
#18
Kazuya Takeda, Kentaro Takanami, Yuko Shirata, Takaya Yamamoto, Noriyoshi Takahashi, Kengo Ito, Kei Takase, Keiichi Jingu
We evaluated the reproducibility and predictive value of texture parameters and existing parameters of 18F-FDG PET/CT images in Stage I non-small-cell lung cancer (NSCLC) patients treated with stereotactic body radiotherapy (SBRT). Twenty-six patients with Stage I NSCLC (T1-2N0M0) were retrospectively analyzed. All of the patients underwent an 18F-FDG PET/CT scan before treatment and were treated with SBRT. Each tumor was delineated using PET Edge (MIM Software Inc., Cleveland, OH), and texture parameters were calculated using open-source code CGITA...
September 21, 2017: Journal of Radiation Research
https://www.readbyqxmd.com/read/29031526/the-temporal-artery-island-flap-a-good-reconstructive-option-for-small-to-medium-sized-facial-defects
#19
Said Algan, Murat Kara, Hakan Cinal, Ensar Zafer Barin, Akin Inaloz, Onder Tan
PURPOSE: The reconstruction of facial defects is esthetically vital because of the unique skin color and texture of the face. The aim of this study was to show the utility of different temporal artery island flap designs for the reconstruction of upper and middle facial defects without contrast to the color and texture of the face. MATERIALS AND METHODS: This study is a retrospective case series conducted from November 2004 through May 2015. Patients older than 18 years with upper and middle facial defects smaller than 5 cm were included...
September 19, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29025727/ct-texture-analysis-potentially-predicts-local-failure-in-head-and-neck-squamous-cell-carcinoma-treated-with-chemoradiotherapy
#20
H Kuno, M M Qureshi, M N Chapman, B Li, V C Andreu-Arasa, K Onoue, M T Truong, O Sakai
BACKGROUND AND PURPOSE: The accurate prediction of prognosis and failure is crucial for optimizing treatment strategies for patients with cancer. The purpose of this study was to assess the performance of pretreatment CT texture analysis for the prediction of treatment failure in primary head and neck squamous cell carcinoma treated with chemoradiotherapy. MATERIALS AND METHODS: This retrospective study included 62 patients diagnosed with primary head and neck squamous cell carcinoma who underwent contrast-enhanced CT examinations for staging, followed by chemoradiotherapy...
October 12, 2017: AJNR. American Journal of Neuroradiology
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