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https://www.readbyqxmd.com/read/27903039/management-of-bipolar-disorder-over-the-perinatal-period
#1
Philip Boyce, Anne Buist
BACKGROUND: Women with bipolar disorder have a high risk of relapse following childbirth. The risk of relapse can be reduced by mood stabilisers, but they are potentially harmful to the developing fetus. OBJECTIVE: The objective of this article is to provide an up-to-date review of the strategies for managing women with bipolar disorder over the perinatal period. DISCUSSION: Discussing the risks of taking mood stabilisers or having a medication-free pregnancy is essential for women with bipolar disorder...
December 2016: Australian Family Physician
https://www.readbyqxmd.com/read/27892736/therapeutics-of-postpartum-depression
#2
Michael Thomson, Verinder Sharma
Postpartum depression is a prevalent disorder affecting many women of reproductive age. Despite increasing public awareness, it is frequently underdiagnosed and undertreated leading to significant maternal morbidity and adverse child outcomes. When identified, postpartum depression is usually treated as major depressive disorder. Many studies have identified the postpartum as a period of high risk for first presentations and relapses of bipolar disorder. Areas Covered: This article reviews the acute and prophylactic treatment of postpartum major depressive disorder, bipolar depression and major depressive disorder with mixed features...
November 28, 2016: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/27889597/is-there-any-association-between-toxoplasma-gondii-infection-and-bipolar-disorder-a-systematic-review-and-meta-analysis
#3
João Luís Vieira Monteiro de Barros, Izabela Guimarães Barbosa, Haitham Salem, Natalia Pessoa Rocha, Arthur Kummer, Olaoluwa O Okusaga, Jair C Soares, Antonio Lucio Teixeira
BACKGROUND: The relationship between Toxoplasma gondii infection and the development of bipolar disorder (BD) has long been investigated, yet to date it is still poorly understood and documented. The aim of this review is to derive a summary estimate of the strength of the association between infection with T. gondii and BD from the available published studies. METHODS: A systematic review was performed using PubMed, LILACS, PsycINFO, and Embase databases. Studies which included a proportion of seropositive BD patients and controls were further examined in a meta-analysis...
November 17, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27857964/women-with-postpartum-weight-retention-have-delayed-wake-times-and-decreased-sleep-efficiency-during-the-perinatal-period-a-brief-report
#4
K M Sharkey, G M Boni, J A Quattrucci, S Blatch, S N Carr
OBJECTIVE: This study assessed sleep and circadian rhythms across the perinatal period in new mothers with and without postpartum weight retention (PPWR). METHODS: Weight was measured at 2 and 16 weeks postpartum in 21 women with previous major depression or bipolar disorder (mean age 29.5±4.7 years) who self-reported pre-pregnancy weight during third trimester. Wrist actigraphy was acquired at 33 weeks gestation and postpartum weeks 2, 6, and 16. Circadian phase was measured at 33 weeks gestation and 6 weeks postpartum...
September 2016: Sleep Health
https://www.readbyqxmd.com/read/27856157/the-serological-evidence-for-maternal-influenza-as-risk-factor-for-psychosis-in-offspring-is-insufficient-critical-review-and-meta-analysis
#5
REVIEW
Jean-Paul Selten, Fabian Termorshuizen
Maternal influenza during pregnancy has been suggested to increase the psychosis risk for the offspring. This hypothesis has been tested using "ecological" studies, which examined the risk for individuals born after epidemics, and "serological" studies, based on serological evidence. A study of the latter type obtained an increased schizophrenia risk for individuals exposed during the first trimester. A second study found a relationship between influenza at any time during gestation and risk for bipolar disorder with psychotic features...
November 14, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/27852343/pregnancy-and-bipolar-disorder-the-risk-of-recurrence-when-discontinuing-treatment-with-mood-stabilisers-a-systematic-review
#6
Erik Roj Larsen, Kristina Saric
OBJECTIVE: Bipolar disorder in pregnancy may be difficult to treat. The dilemma is whether the women should continue medication throughout pregnancy, and maybe accept a minor risk to harm their unborn child, or discontinue medication and increase the risk of recurrence, which can lead to maternal morbidity, thereby endangering themselves and their foetus. Design and methods In September 2016, three electronic search databases; PubMed, Scopus and PsycInfo, were used searching for clinical trials concerning this question...
November 17, 2016: Acta Neuropsychiatrica
https://www.readbyqxmd.com/read/27810616/exposure-to-tobacco-smoke-in-utero-or-during-early-childhood-and-risk-of-hypomania-prospective-birth-cohort-study
#7
D F Mackay, J J Anderson, J P Pell, S Zammit, D J Smith
OBJECTIVES: Using data from a prospective birth cohort, we aimed to test for an association between exposure to tobacco smoke in utero or during early development and the experience of hypomania assessed in young adulthood. METHODS: We used data on 2957 participants from a large birth cohort (Avon longitudinal study of parents and children [ALSPAC]). The primary outcome of interest was hypomania, and the secondary outcome was "hypomania plus previous psychotic experiences (PE)"...
October 28, 2016: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/27809629/prophylactic-use-of-olanzapine-and-quetiapine-from-pregnancy-to-the-postpartum-period-in-women-with-bipolar-disorder-a-case-series
#8
Faruk Uguz
The management of bipolar disorder in pregnant and postpartum women is one of the most difficult issues in clinical practice. Data on the efficacy of mood stabilizers, except lithium and antipsychotics, in the maintenance treatment of bipolar disorders during pregnancy and postpartum period are very limited. This report presents results of prophylaxis with olanzapine and quetiapine with regards to affective episodes in pregnancy to the postpartum period.
November 3, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27793111/bipolar-disorder-in-pregnancy-and-childbirth-a-systematic-review-of-outcomes
#9
Marie Rusner, Marie Berg, Cecily Begley
BACKGROUND: Bipolar Disorder (BD) is a mental disorder usually diagnosed between 18 and 30 years of age; this coincides with the period when many women experience pregnancy and childbirth. As specific problems have been reported in pregnancy and childbirth when the mother has BD, a systematic review was carried out to summarise the outcomes of pregnancy and childbirth, in mother and child, when the mother has BD diagnosed before pregnancy. METHODS: An a priori protocol was designed and a systematic search conducted in PubMed, CINAHL, Scopus, PsycINFO and Cochrane databases in March 2015...
October 28, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27769136/peripartum-management-of-bipolar-disorder-what-do-the-latest-guidelines-recommend
#10
Verinder Sharma, Sapna Sharma
Many women with bipolar disorder experience significant morbidity during pregnancy and the postpartum period. The use of evidence-based and up-to-date guidelines has the potential to improve maternal and neonatal care. We review the latest clinical practice guidelines to gather recommendations for the peripartum management of bipolar disorder. Areas covered: Three electronic databases, MEDLINE/PubMed, the Cochrane Library, and the National Guidelines Clearinghouse were searched using various combinations of the following terms: bipolar disorder, pregnancy, postpartum, peripartum, puerperal, antenatal, postnatal, and guidelines...
October 21, 2016: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/27744125/gestational-maternal-c-reactive-protein-and-risk-of-bipolar-disorder-among-young-individuals-in-a-nationwide-birth-cohort
#11
Roshan Chudal, Andre Sourander, Heljä-Marja Surcel, Dan Sucksdorff, Susanna Hinkka-Yli-Salomäki, Alan S Brown
OBJECTIVES: C-reactive protein (CRP) is a well-established general marker of inflammation from both infectious and noninfectious exposures. Previous studies have shown that maternal CRP is associated with an increased risk of autism and schizophrenia. The aim of this study was to examine the association between early to mid-gestational serum CRP levels, prospectively assayed in maternal sera, and the risk of bipolar disorder (BPD). METHODS: This study is derived from the Finnish Prenatal Study of Bipolar Disorder (FIPS-B), based on a nested case-control study design...
October 11, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27738382/maternal-and-fetal-outcomes-after-lamotrigine-use-in-pregnancy-a-retrospective-analysis-from-an-urban-maternal-mental-health-centre-in-new-zealand
#12
Chandni Prakash, Susan Hatters-Friedman, Charmian Moller-Olsen, Abigail North
INTRODUCTION: Pregnancy is a vulnerable period for recurrence of bipolar disorder. Discontinuation of mood stabilisers during pregnancy and the postpartum period can significantly increase the risk of recurrence of bipolar disorder. Lamotrigine is an anti-epileptic drug that has been approved for the maintenance treatment of bipolar disorder. Epilepsy literature has indicated that lamotrigine has a reassuring safety profile in pregnancy but there is little information on its effectiveness and safety in pregnant women with mental disorders...
August 15, 2016: Psychopharmacology Bulletin
https://www.readbyqxmd.com/read/27719778/assessment-and-care-of-childbearing-women-with-severe-and-persistent-mental-illness
#13
Amy McKeever, SueEllen Alderman, Stephanie Luff, Brian DeJesus
Severe and persistent mental illness (SPMI) refers to complex mood disorders that include major depressive disorder with or without psychosis; severe anxiety disorders resistant to treatment; affective psychotic disorders including bipolar affective disorder, schizophrenia, and schizoaffective disorder; and other nonaffective subtypes of schizophrenia. SPMIs affect 1 in 17 people and are among the leading causes of disability and impaired health-related quality of life in the United States. Caring for childbearing women with preexisting SPMI can be challenging for maternal-child health clinicians...
October 2016: Nursing for Women's Health
https://www.readbyqxmd.com/read/27703792/women-with-bipolar-disorder-and-pregnancy-factors-influencing-their-decision-making
#14
Clare Dolman, Ian R Jones, Louise M Howard
BACKGROUND: Women with bipolar disorder are at increased risk of having a severe episode of illness associated with childbirth. AIMS: To explore the factors that influence the decision-making of women with bipolar disorder regarding pregnancy and childbirth. METHOD: Qualitative study with a purposive sample of women with bipolar disorder considering pregnancy, or currently or previously pregnant, supplemented by data from an online forum. Data were analysed using thematic analysis...
September 2016: BJPsych Open
https://www.readbyqxmd.com/read/27570512/suicide-during-perinatal-period-epidemiology-risk-factors-and-clinical-correlates
#15
REVIEW
Laura Orsolini, Alessandro Valchera, Roberta Vecchiotti, Carmine Tomasetti, Felice Iasevoli, Michele Fornaro, Domenico De Berardis, Giampaolo Perna, Maurizio Pompili, Cesario Bellantuono
Perinatal period may pose a great challenge for the clinical management and treatment of psychiatric disorders in women. In fact, several mental illnesses can arise during pregnancy and/or following childbirth. Suicide has been considered a relatively rare event during the perinatal period. However, in some mental disorders (i.e., postpartum depression, bipolar disorder, postpartum psychosis, etc.) have been reported a higher risk of suicidal ideation, suicide attempt, or suicide. Therefore, a complete screening of mothers' mental health should also take into account thoughts of suicide and thoughts about harming infants as well...
2016: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/27514299/adverse-effects-in-the-pharmacologic-management-of-bipolar-disorder-during-pregnancy
#16
REVIEW
Charlotte S Hogan, Marlene P Freeman
Management of bipolar disorder during pregnancy often involves medications with potential adverse effects, including risks to the mother and fetus. Although some specifics are known, many medications continue to have incompletely characterized reproductive safety profiles. Women with bipolar disorder who are planning pregnancy face challenging decisions about their treatment; careful risk-benefit discussions are necessary. With the goal of further informing these discussions, this article reviews the data currently available regarding medication safety in the management of bipolar disorder during pregnancy, with specific attention to lithium, valproic acid, lamotrigine, carbamazepine, and antipsychotic medications...
September 2016: Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/27477922/maternal-serum-cytokine-levels-and-risk-of-bipolar-disorder
#17
Keely Cheslack-Postava, Serge Cremers, Yuanyuan Bao, Ling Shen, Catherine A Schaefer, Alan S Brown
Prenatal exposure to influenza has previously been associated with increased risk of bipolar disorder (BD), an association that may be mediated by maternal cytokines. The objective of this study was to determine the association between maternal levels of cytokines measured during each trimester of pregnancy and the risk of BD in offspring. We conducted a case-control study nested in the Child Health and Development Study, a birth cohort that enrolled pregnant women in 1959-1966. Potential cases with DSM-IV-TR bipolar I disorder, bipolar II disorder, BD not otherwise specified, and BD with psychotic features were ascertained through electronic medical records, a public agency database, and a mailing to the cohort...
July 29, 2016: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/27456195/-mental-disorders-in-pregnancy-and-postpartum-prevalence-course-and-clinical-diagnostics
#18
C Kühner
The peripartum period represents a critical phase for the onset and course of mental disorders. During this phase, mental disorders occur as first onset or, more often, as recurrent or ongoing chronic conditions with onset and further course of illness in- or outside the peripartal period. No clear risk increase exists for the more prevalent mental disorders such as depressive and anxiety disorders during this period, whereas there is an increased risk for bipolar disorder. Peripartal mental disorders may impact fetal and child development through different mechanisms...
September 2016: Der Nervenarzt
https://www.readbyqxmd.com/read/27448177/-treatment-of-psychiatric-disorders-during-pregnancy-and-the-breast-feeding-psychotherapy-and-other-nondrug-therapies
#19
S Kittel-Schneider, A Reif
The majority of women suffering from psychiatric disorders in pregnancy and the breast feeding prefer psychotherapy and other nonpharmacological treatment over psychopharmacological treatment although the risk of malformations and postnatal complications in children exposed to psychopharmacological drugs must be regarded as acceptable in moderate to severely ill patients. Data are lacking, but several psychotherapeutic and biological treatments as well as noninvasive brain stimulation procedures have been investigated to treat depressive episodes and anxiety disorders in pregnancy and the breast feeding...
September 2016: Der Nervenarzt
https://www.readbyqxmd.com/read/27364100/safety-of-hormonal-contraception-and-intrauterine-devices-among-women-with-depressive-and-bipolar-disorders-a-systematic-review
#20
H Pamela Pagano, Lauren B Zapata, Erin N Berry-Bibee, Kavita Nanda, Kathryn M Curtis
BACKGROUND: Women with depressive or bipolar disorders are at an increased risk for unintended pregnancy. OBJECTIVE: To examine the safety of hormonal contraception among women with depressive and bipolar disorders. METHODS: We searched for articles published through January 2016 on the safety of using any hormonal contraceptive method among women with depressive or bipolar disorders, including those who had been diagnosed clinically or scored above threshold levels on a validated screening instrument...
June 27, 2016: Contraception
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