keyword
https://read.qxmd.com/read/38537140/first-report-of-soybean-root-rot-caused-by-fusarium-proliferatum-in-the-republic-of-korea
#1
JOURNAL ARTICLE
In-Jeong Kang, Mirang Lee, Sang Yun Han, Yul-Ho Kim, Sungwoo Lee
Fusarium species are widespread soilborne pathogens that can cause damping-off, root rot, and wilting in soybean [ Glycine max (L.) Merrill], subsequently leading to significant yield suppression. Several Fusarium spp. have already been documented for their pathogenicity on soybean plants in the Republic of Korea. The nationwide monitoring of soybean diseases continues to identify new pathogenic Fusarium spp. In 2016, five plant samples at R3-R4 growth stages, showing symptoms of wilting in the upper parts and root rot, were collected in Suwon, Gyeonggi, Republic of Korea...
March 27, 2024: Plant Disease
https://read.qxmd.com/read/38537038/novel-optical-coherence-tomography-findings-in-a-patient-with-methanol-toxicity-a-case-report
#2
Burcu Işık, Mehmet Giray Ersoz, Mehmet Dokur, Ismail Yıldız, Mehmet Sami Islamoğlu
We report a case of acute methanol toxicity with unique optical coherence tomography findings. A 56-year-old man was referred to our ophthalmology clinic with a history of handmade vodka consumption and vision loss. On ophthalmologic examination, his vision was 20/100 in his right eye and 20/200 in his left eye. Bilateral mild optic disk hyperemia was detected on fundus examination. Because of the severity of systemic symptoms in such cases, it is very difficult to include optical coherence tomography in the ophthalmologic examination...
2024: Arquivos Brasileiros de Oftalmologia
https://read.qxmd.com/read/38537031/anti-biofilm-effectiveness-of-protocols-for-cleaning-complete-dentures-in-hospitalized-patients-a-randomized-controlled-trial
#3
JOURNAL ARTICLE
Anna Clara Gurgel Gomes, Janaina Gomes Maciel, Amanda Aparecida Maia Neves Garcia, Letycia Accioly Simões Coelho, Giulia Murcia Rodrigues, Vinicius Carvalho Porto, Grigorios Polyzois, Marlise Inêz Klein, Simone Soares, Vanessa Migliorini Urban, Karin Hermana Neppelenbroek
BACKGROUND: Denture biofilm acts as a potential reservoir for respiratory pathogens, considerably increasing the risk of lung infections, specifically aspiration pneumonia, mainly 48h after hospital admission. The establishment of a straightforward, affordable, and applicable hygiene protocol in a hospital environment for the effective control of denture biofilm can be particularly useful to prevent respiratory infections or reduce the course of established lung disease. OBJECTIVES: To evaluate the anti-biofilm effectiveness of denture cleaning protocols in hospitalized patients...
2024: Journal of Applied Oral Science: Revista FOB
https://read.qxmd.com/read/38537021/impact-of-access-cavity-design-on-fracture-resistance-of-endodontically-treated-maxillary-first-premolar-in-vitro
#4
JOURNAL ARTICLE
Anju Daniel, Abdul Rahman Saleh, Anas Al-Jadaa, Waad Kheder
This study was designed to investigate the impact of access cavity designs on fracture resistance of endodontically treated maxillary first premolars. The study sample consisted of 72 intact maxillary first premolars, randomly divided into six groups (n = 12). A standardized proximal cavity preparation was prepared for all samples using standard bur. Groups I: control group with only standard proximal cavity and no endodontic access, group II: Truss access cavity, group III: Separated access to buccal and palatal canals without removal of dentine in between, group IV: Access to buccal and palatal canals with removal of dentine in between, group V: Traditional access cavity, group VI: Mesio-occlusal-distal cavity (MOD)...
2024: Brazilian Dental Journal
https://read.qxmd.com/read/38536957/bismuth-doping-boosting-na-diffusion-kinetics-of-layered-oxide-cathode-with-radially-oriented-010-active-lattice-facet-for-sodium-ion-batteries
#5
REVIEW
Yu-Xin Chang, Yu-Jie Guo, Ya-Xia Yin, Wei-Huan He, Mengmeng Yan, Li-Rong Zheng, Jing Zhang, Qinghua Zhang, Dong Su, Xing Zhang, Jianfeng Mao, Guanjie Li, Shilin Zhang, Sailong Xu
O3-type layered oxide cathodes (Na x TMO2 ) for sodium-ion batteries (SIBs) have attracted significant attention as one of the most promising potential candidates for practical energy storage applications. The poor Na+ diffusion kinetics is, however, one of the major obstacles to advancing large-scale practical application. Herein, we report bismuth-doped O3-NaNi0.5 Mn0.5 O2 (NMB) microspheres consisting of unique primary nanoplatelets with the radially oriented {010} active lattice facets. The NMB combines the advantages of the oriented and exposed electrochemical active planes for direct paths of Na+ diffusion, and the thick primary nanoplatelets for less surface parasitic reactions with the electrolyte...
March 27, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38536738/spectrophotometric-analysis-of-apical-extrusion-of-sodium-hypochlorite-using-different-irrigation-protocols-in-an-ex-vivo-model-of-immature-teeth
#6
JOURNAL ARTICLE
W Viera, L Gonçalves, V A B Dos Santos, B P F A Gomes, C C Ferraz, J F de Almeida, M Marciano, M Frozoni, A de-Jesus-Soares
OBJECTIVE: To evaluate the effect of different agitation methods on apical extrusion of 1.5% sodium hypochlorite (NaOCl) in an ex vivo model of immature teeth. METHODS: Sixty extracted human inferior incisors were prepared to simulate immature teeth and embedded in an artificial root socket made of silicone impression material. The teeth were then divided into four groups: Conventional needle irrigation (CNI) alone, CNI supplemented with Ultrasonic Irrigant Activation (UIA), EasyClean (EC), or XP-endo Finisher (XPF)...
February 21, 2024: European Journal of Prosthodontics and Restorative Dentistry
https://read.qxmd.com/read/38536657/increased-risk-of-erythrocytosis-in-men-with-type-2-diabetes-treated-with-combined-sodium-glucose-cotransporter-2-inhibitor-and-testosterone-replacement-therapy
#7
JOURNAL ARTICLE
A R Gosmanov, D E Gemoets, K A Schumacher
PURPOSE: In clinical trials, sodium-glucose cotransporter-2 inhibitors (SGLT-2i) and testosterone replacement therapy (TRT) were shown to stimulate red blood cell production. Little is known if combination therapy poses risk of erythrocytosis in real world clinical practice. METHODS: This was a retrospective nationwide cohort study of US Veterans with type 2 diabetes (T2D) and baseline hematocrit between 38 and 50% who were prescribed SGLT-2i and/or TRT between 3/2013 and 10/2022 and had adequate adherence based on the proportion of days covered > 80%...
March 27, 2024: Journal of Endocrinological Investigation
https://read.qxmd.com/read/38536656/development-of-a-diagnostic-model-for-pre-washout-screening-of-primary-aldosteronism
#8
JOURNAL ARTICLE
Q Wang, H Dong, H-W Li, Z-H Zheng, Y-Z Liu, Y-H Hua, Y-J Xiong, H-M Zhang, L Song, Y-B Zou, X-J Jiang
PURPOSE: Primary aldosteronism (PA) diagnosis is affected by antihypertensive drugs that are commonly taken by patients with suspected PA. In this study, we developed and validated a diagnostic model for screening PA without drug washout. METHODS: We retrospectively analyzed 1095 patients diagnosed with PA or essential hypertension. Patients were randomly grouped into training and validation sets at a 7:3 ratio. Baseline characteristics, plasma aldosterone concentration (PAC), and direct renin concentration (DRC) before and after drug washout were separately recorded, and the aldosterone-to-renin ratio (ARR) was calculated...
March 27, 2024: Journal of Endocrinological Investigation
https://read.qxmd.com/read/38536635/the-acetic-acid-produced-by-lactobacillus-species-regulates-immune-function-to-alleviate-pedv-infection-in-piglets
#9
JOURNAL ARTICLE
Ming-Jie Sun, Jun Hong Xing, Qing-Song Yan, Bo-Shi Zou, Ying-Jie Wang, Tian-Ming Niu, Tong Yu, Hai-Bin Huang, Di Zhang, Shu-Min Zhang, Wu-Sheng Sun, Ruo-Nan Zou, Chun-Feng Wang, Chun-Wei Shi
Porcine epidemic diarrhea virus (PEDV) infection results in significant mortality among newborn piglets, leading to substantial economic setbacks in the pig industry. Short-chain fatty acids (SCFA), the metabolites of intestinal probiotics, play pivotal roles in modulating intestinal function, enhancing the intestinal barrier, and bolstering immune responses through diverse mechanisms. The protective potential of Lactobacillus delbrueckii, Lactobacillus johnsonii, and Lactococcus lactis was first noted when administered to PEDV-infected piglets...
March 27, 2024: Probiotics and Antimicrobial Proteins
https://read.qxmd.com/read/38536629/association-of-premorbid-glp-1ra-and-sglt-2i-prescription-alone-and-in-combination-with-covid-19-severity
#10
JOURNAL ARTICLE
Klara R Klein, Trine J Abrahamsen, Anna R Kahkoska, G Caleb Alexander, Christopher G Chute, Melissa Haendel, Stephanie S Hong, Hemalkumar Mehta, Richard Moffitt, Til Stürmer, Kajsa Kvist, John B Buse
INTRODUCTION: People with type 2 diabetes are at heightened risk for severe outcomes related to COVID-19 infection, including hospitalization, intensive care unit admission, and mortality. This study was designed to examine the impact of premorbid use of glucagon-like peptide-1 receptor agonist (GLP-1RA) monotherapy, sodium-glucose cotransporter-2 inhibitor (SGLT-2i) monotherapy, and concomitant GLP1-RA/SGLT-2i therapy on the severity of outcomes in individuals with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection...
March 27, 2024: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://read.qxmd.com/read/38536573/sodium-hydroxide-magnesium-chloride-multistage-activated-sludge-biochar-interfacial-chemical-behavior-and-cd-ii-adsorption-performance
#11
JOURNAL ARTICLE
Chao Yan, Guojun Cai
To enhance the adsorption performance of municipal sludge biochar on Cd(II), modified sludge biochar was prepared by sodium hydroxide/magnesium chloride (NaOH/MgCl2 ) graded activation, and the Cd(II) adsorption performance on sludge biochar (BC), NaOH-activated sludge biochar (NBC) and NaOH/MgCl2 activated sludge biochar (NBC-Mg) was investigated. The results showed that NaOH/MgCl2 graded activation upgraded the surface structure and enhanced the graphitization of sludge biochar. The adsorption experiments indicated that the adsorption kinetic and adsorption isotherm for Cd(II) were in accordance with the pseudo second-order kinetic and Langmuir model...
March 27, 2024: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38536494/the-role-of-na-coupled-bicarbonate-transporters-ncbt-in-health-and-disease
#12
REVIEW
Shannon R Holmberg, Yohei Sakamoto, Akira Kato, Michael F Romero
Cellular and organism survival depends upon the regulation of pH, which is regulated by highly specialized cell membrane transporters, the solute carriers (SLC) (For a comprehensive list of the solute carrier family members, see: https://www.bioparadigms.org/slc/ ). The SLC4 family of bicarbonate (HCO3 - ) transporters consists of ten members, sorted by their coupling to either sodium (NBCe1, NBCe2, NBCn1, NBCn2, NDCBE), chloride (AE1, AE2, AE3), or borate (BTR1). The ionic coupling of SLC4A9 (AE4) remains controversial...
March 27, 2024: Pflügers Archiv: European Journal of Physiology
https://read.qxmd.com/read/38536176/estimated-sustainable-cost-based-prices-for-diabetes-medicines
#13
JOURNAL ARTICLE
Melissa J Barber, Dzintars Gotham, Helen Bygrave, Christa Cepuch
IMPORTANCE: The burden of diabetes is growing worldwide. The costs associated with diabetes put substantial pressure on patients and health budgets, especially in low- and middle-income countries. The prices of diabetes medicines are a key determinant for access, yet little is known about the association between manufacturing costs and current market prices. OBJECTIVES: To estimate the cost of manufacturing insulins, sodium-glucose cotransporter 2 inhibitors (SGLT2Is), and glucagonlike peptide 1 agonists (GLP1As), derive sustainable cost-based prices (CBPs), and compare these with current market prices...
March 4, 2024: JAMA Network Open
https://read.qxmd.com/read/38536153/prognostic-models-for-mortality-and-morbidity-in-heart-failure-with-preserved-ejection-fraction
#14
JOURNAL ARTICLE
Kirsty McDowell, Toru Kondo, Atefeh Talebi, Ken Teh, Erasmus Bachus, Rudolf A de Boer, Ross T Campbell, Brian Claggett, Ashkay S Desai, Kieran F Docherty, Adrian F Hernandez, Silvio E Inzucchi, Mikhail N Kosiborod, Carolyn S P Lam, Felipe Martinez, Joanne Simpson, Muthiah Vaduganathan, Pardeep S Jhund, Scott D Solomon, John J V McMurray
IMPORTANCE: Accurate risk prediction of morbidity and mortality in patients with heart failure with preserved ejection fraction (HFpEF) may help clinicians risk stratify and inform care decisions. OBJECTIVE: To develop and validate a novel prediction model for clinical outcomes in patients with HFpEF using routinely collected variables and to compare it with a biomarker-driven approach. DESIGN, SETTING, AND PARTICIPANTS: Data were used from the Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved Ejection Fraction Heart Failure (DELIVER) trial to derive the prediction model, and data from the Angiotensin Receptor Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction (PARAGON-HF) and the Irbesartan in Heart Failure With Preserved Ejection Fraction Study (I-PRESERVE) trials were used to validate it...
March 27, 2024: JAMA Cardiology
https://read.qxmd.com/read/38535825/comprehensive-analysis-of-bufadienolide-and-protein-profiles-of-gland-secretions-from-medicinal-bufo-species
#15
JOURNAL ARTICLE
Yunge Fang, Liangmian Chen, Pengfei Wang, Yating Liu, Yuxiu Wang, Zhimin Wang, Yue Ma, Huimin Gao
Toad Venom (TV) is the dried product of toxic secretions from Bufo bufo gargarizans Cantor (BgC) or B. melanostictus Schneider (BmS). Given the increasing medical demand and the severe depletion of wild toads, a number of counterfeit TVs appeared on the market, posing challenges to its quality control. In order to develop an efficient, feasible, and comprehensive approach to evaluate TV quality, a thorough analysis and comparison of chemical compounds among legal species BgC and BmS, as well as the main confusion species B...
March 20, 2024: Toxins
https://read.qxmd.com/read/38535818/immunochemical-recognition-of-bothrops-rhombeatus-venom-by-two-polyvalent-antivenoms
#16
JOURNAL ARTICLE
Karen Sarmiento, Jorge Zambrano, Carlos Galvis, Álvaro Molina-Olivares, Marisol Margarita Villadiego-Molinares, Johanna Alejandra Ramírez-Martínez, Ana Lucía Castiblanco, Fabio A Aristizabal
The protein profile of Bothrops rhombeatus venom was compared to Bothrops asper and Bothrops atrox, and the effectiveness of antivenoms from the National Institute of Health of Colombia (INS) and Antivipmyn-Tri (AVP-T) of Mexico were analyzed. Protein profiles were studied with sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and reverse-phase high-performance liquid chromatography (RP-HPLC). The neutralizing potency and the level of immunochemical recognition of the antivenoms to the venoms were determined using Western blot, affinity chromatography, and enzyme-linked immunosorbent assay (ELISA)...
March 15, 2024: Toxins
https://read.qxmd.com/read/38535792/characterization-of-sodium-channel-peptides-obtained-from-the-venom-of-the-scorpion-centruroides-bonito
#17
JOURNAL ARTICLE
Rita Restano-Cassulini, Timoteo Olamendi-Portugal, Lidia Riaño-Umbarila, Fernando Z Zamudio, Gustavo Delgado-Prudencio, Baltazar Becerril, Lourival D Possani
Five peptides were isolated from the venom of the Mexican scorpion Centruroides bonito by chromatographic procedures (molecular weight sieving, ion exchange columns, and HPLC) and were denoted Cbo1 to Cbo5. The first four peptides contain 66 amino acid residues and the last one contains 65 amino acids, stabilized by four disulfide bonds, with a molecular weight spanning from about 7.5 to 7.8 kDa. Four of them are toxic to mice, and their function on human Na+ channels expressed in HEK and CHO cells was verified...
March 1, 2024: Toxins
https://read.qxmd.com/read/38535783/sensitive-detection-of-ciguatoxins-using-a-neuroblastoma-cell-based-assay-with-voltage-gated-potassium-channel-inhibitors
#18
JOURNAL ARTICLE
Toshiaki Yokozeki, Madoka Kawabata, Kazuhiro Fujita, Masahiro Hirama, Takeshi Tsumuraya
Ciguatoxins (CTXs) are neurotoxins responsible for ciguatera poisoning (CP), which affects more than 50,000 people worldwide annually. The development of analytical methods to prevent CP is a pressing global issue, and the N2a assay is one of the most promising methods for detecting CTXs. CTXs are highly toxic, and an action level of 0.01 μg CTX1B equivalent (eq)/kg in fish has been proposed. It is desirable to further increase the detection sensitivity of CTXs in the N2a assay to detect such low concentrations reliably...
February 29, 2024: Toxins
https://read.qxmd.com/read/38535754/structure-and-morphology-of-red-pigments-based-on-sepiolite
#19
JOURNAL ARTICLE
I Carrillo, E Atanes-Sánchez, F Fernández-Martínez
Sepiolite is an important raw fibrous material. A method to prepare red pigments based on sepiolite through the thermal treatment of sepiolite with sulfur and sodium sulfide hydrate is reported. Sepiolite was heated until 800 °C in order to remove zeolitic water, the first coordinated water, the second coordinated water, and structural hydroxyls. Several [S/Na2 S]molar ratios in the range 0.5-7 were employed. The properties of these pigments were studied by different analytical techniques, such as colorimetric analysis, thermal analysis, Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction and scanning electron microscopy...
March 27, 2024: Dalton Transactions: An International Journal of Inorganic Chemistry
https://read.qxmd.com/read/38535660/the-pd-ii-reduction-mechanisms-in-bacillus-megaterium-y-4-revealed-by-proteomic-analysis
#20
JOURNAL ARTICLE
Yuan Chen, Jiaxing Wang, Daidi Chen, Boxi Wang, Jinchuan Wu, Rongrong Liu, Qingxin Li
Many studies have been conducted on the microbial reduction of Pd (II) to palladium nanoparticles (Pd-NPs) due to the environmental friendliness, low cost, and the decreased toxicity of Pd (II) ions. In this study, we investigate the reduction mechanism of Pd (II) by Bacillus megaterium Y-4 through proteomics. The data are available via ProteomeXchange with identifier PXD049711. Our results revealed that B. megaterium Y-4 may use the endogenous electron donor (NAD(P)H) generated by nirB, tdh, and fabG and reductase to reduce Pd (II) to Pd-NPs...
March 12, 2024: Nanomaterials
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