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https://www.readbyqxmd.com/read/28827614/sodium-hyaluronate-in-the-treatment-of-dry-eye-syndrome-a-systematic-review-and-meta-analysis
#1
Bryan Chin Hou Ang, James Jie Sng, Priscilla Xin Hui Wang, Hla Myint Htoon, Louis Hak Tien Tong
This systematic review and meta-analysis compares sodium hyaluronate (HY) with non-HY based artificial tears in the treatment of dry eye syndrome. A literature search for clinical trials comparing HY against non-HY preparations was conducted across PubMed, Cochrane Central Register of Controlled Trials and Scopus databases from inception up to May 2016. Majority of the 18 studies selected for review showed superiority of HY in improving ocular staining and symptoms. Randomized controlled trials (RCTs) examining Schirmer's I (SH) and tear breakup time (TBUT) underwent further meta-analyses with calculation of pooled standardized mean differences (SMDs) with 95% confidence intervals (CIs)...
August 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28814023/representing-high-dimensional-data-to-intelligent-prostheses-and-other-wearable-assistive-robots-a-first-comparison-of-tile-coding-and-selective-kanerva-coding
#2
Jaden B Travnik, Patrick M Pilarski
Prosthetic devices have advanced in their capabilities and in the number and type of sensors included in their design. As the space of sensorimotor data available to a conventional or machine learning prosthetic control system increases in dimensionality and complexity, it becomes increasingly important that this data be represented in a useful and computationally efficient way. Well structured sensory data allows prosthetic control systems to make informed, appropriate control decisions. In this study, we explore the impact that increased sensorimotor information has on current machine learning prosthetic control approaches...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28811095/can-the-optimum-artificial-tear-treatment-for-dry-eye-disease-be-predicted-from-presenting-signs-and-symptoms
#3
Laika Essa, Deborah Laughton, James S Wolffsohn
PURPOSE: To assess dry eye treatment with four preservative-free dry eye artificial tear treatments to facilitate evidence-based prescribing. METHODS: A randomised, single masked crossover trial of Clinitas Soothe, Hyabak, Tears Again and TheraTears artificial tears was conducted on 50 symptomatic dry eye patients, aged 60.8±14.2years. At baseline and after trialling each treatment for 4 weeks, signs and symptoms were assessed using the Ocular Surface Disease Index (OSDI), non-invasive tear break-up time, fluorescein tear break-up time, tear meniscus height (TMH), Phenol Red test, lid-parallel conjunctival folds (LIPCOF), ocular surface staining, and lipid layer grading and osmolarity (baseline visit only)...
August 12, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28802684/-management-of-post-traumatic-aphakia-and-aniridia-retrospective-study-of-17-patients-undergoing-scleral-sutured-artificial-iris-intraocular-lens-implantation-management-of-aphakia-aniridia-with-scleral-sutured-artificial-iris-intraocular-lenses
#4
A-S Villemont, V Kocaba, H Janin-Manificat, L Abouaf, M Poli, A-S Marty, M Rabilloud, J Fleury, C Burillon
PURPOSE: To evaluate the long-term outcomes of artificial iris intraocular lenses sutured to the sclera for managing traumatic aphakia and aniridia. METHODS: All consecutive cases receiving a Morcher(®) combination implant from June 2008 to February 2016 in Edouard-Herriot Hospital (Lyon, France) were included in this single-center retrospective study. Visual acuity, subjective degree of glare, quality of life and surgical complications were evaluated. RESULTS: Seventeen eyes of 17 patients were included, among which 82% were male...
August 9, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28790941/facial-contrast-is-a-cross-cultural-cue-for-perceiving-age
#5
Aurélie Porcheron, Emmanuelle Mauger, Frédérique Soppelsa, Yuli Liu, Liezhong Ge, Olivier Pascalis, Richard Russell, Frédérique Morizot
Age is a fundamental social dimension and a youthful appearance is of importance for many individuals, perhaps because it is a relevant predictor of aspects of health, facial attractiveness and general well-being. We recently showed that facial contrast-the color and luminance difference between facial features and the surrounding skin-is age-related and a cue to age perception of Caucasian women. Specifically, aspects of facial contrast decrease with age in Caucasian women, and Caucasian female faces with higher contrast look younger (Porcheron et al...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28790800/clinical-utility-of-cyclosporine-csa-ophthalmic-emulsion-0-05-for-symptomatic-relief-in-people-with-chronic-dry-eye-a-review-of-the-literature
#6
REVIEW
Michelle K Rhee, Francis S Mah
To review the literature on the efficacy of cyclosporine (CsA) ophthalmic emulsion 0.05% on symptomatic relief in chronic dry eye disease. There is consistent evidence of objective improvements in chronic dry eye disease (Schirmer score, corneal and interpalpebral dye staining, and tear breakup time) with CsA, but variable results with symptomatic improvement, possibly due to patient tolerance of CsA, similar comforting effect with artificial tears and CsA vehicle, and the inherent subjective nature of symptom monitoring and analysis...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28771187/herbal-supplement-in-a-buffer-for-dry-eye-syndrome-treatment
#7
Hung-Chang Chen, Zhi-Yu Chen, Tsung-Jen Wang, Victor J Drew, Ching-Li Tseng, Hsu-Wei Fang, Feng-Huei Lin
Dry eye syndrome (DES) is one of the most common types of ocular diseases. There is a major need to treat DES in a simple yet efficient way. Artificial tears (AT) are the most commonly used agents for treating DES, but are not very effective. Herbal extractions of ferulic acid (FA), an anti-oxidant agent, and kaempferol (KM), an anti-inflammatory reagent, were added to buffer solution (BS) to replace ATs for DES treatment. The cytotoxicity and anti-inflammatory effects were examined in vitro by co-culture with human corneal epithelial cells (HCECs) to obtain the optimal concentration of KM and FA for treating HCECs...
August 3, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28768473/a-de-novo-missense-mutation-of-fgfr2-causes-facial-dysplasia-syndrome-in-holstein-cattle
#8
Jørgen S Agerholm, Fintan J McEvoy, Steffen Heegaard, Carole Charlier, Vidhya Jagannathan, Cord Drögemüller
BACKGROUND: Surveillance for bovine genetic diseases in Denmark identified a hitherto unreported congenital syndrome occurring among progeny of a Holstein sire used for artificial breeding. A genetic aetiology due to a dominant inheritance with incomplete penetrance or a mosaic germline mutation was suspected as all recorded cases were progeny of the same sire. Detailed investigations were performed to characterize the syndrome and to reveal its cause. RESULTS: Seven malformed calves were submitted examination...
August 2, 2017: BMC Genetics
https://www.readbyqxmd.com/read/28747401/influence-of-scene-structure-and-content-on-visual-search-strategies
#9
Tatiana A Amor, Mirko Luković, Hans J Herrmann, José S Andrade
When searching for a target within an image, our brain can adopt different strategies, but which one does it choose? This question can be answered by tracking the motion of the eye while it executes the task. Following many individuals performing various search tasks, we distinguish between two competing strategies. Motivated by these findings, we introduce a model that captures the interplay of the search strategies and allows us to create artificial eye-tracking trajectories, which could be compared with the experimental ones...
July 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28746814/probabilistic-computations-for-attention-eye-movements-and-search
#10
Miguel P Eckstein
The term visual attention immediately evokes the idea of limited resources, serial processing, or a zoom metaphor. But evidence has slowly accumulated that computations that take into account probabilistic relationships among visual forms and the target contribute to optimizing decisions in biological and artificial organisms, even without considering these limited-capacity processes in covert attention or even foveation. The benefits from such computations can be formalized within the framework of an ideal Bayesian observer and can be related to the classic theory of sensory cue combination in vision science and context-driven approaches to object detection in computer vision...
July 26, 2017: Annual Review of Vision Science
https://www.readbyqxmd.com/read/28743809/prevention-of-ophthalmia-neonatorum-caused-by-neisseria-gonorrhoeae-using-a-fatty-acid-based-formulation
#11
Colin P Churchward, Raid G Alany, Ruth S Kirk, Anthony J Walker, Lori A S Snyder
Ophthalmia neonatorum, also called neonatal conjunctivitis, acquired during delivery can occur in the first 28 days of life. Commonly caused by the bacterial pathogen Neisseria gonorrhoeae, infection can lead to corneal scarring, perforation of the eye, and blindness. One approach that can be taken to prevent the disease is the use of an ophthalmic prophylaxis, which kills the bacteria on the surface of the eye shortly after birth. Current prophylaxes are based on antibiotic ointments. However, N. gonorrhoeae is resistant to many antibiotics and alternative treatments must be developed before the condition becomes untreatable...
July 25, 2017: MBio
https://www.readbyqxmd.com/read/28743725/altered-balance-of-receptive-field-excitation-and-suppression-in-visual-cortex-of-amblyopic-macaque-monkeys
#12
Luke E Hallum, Christopher Shooner, Romesh D Kumbhani, Jenna G Kelly, Virginia García-Marín, Najib J Majaj, J Anthony Movshon, Lynne Kiorpes
In amblyopia, a visual disorder caused by abnormal visual experience during development, the amblyopic eye loses visual sensitivity while the other (fellow) eye is largely unaffected. Binocular vision in amblyopes is often disrupted by interocular suppression. We used 96-electrode arrays to record neurons and neuronal groups in areas V1 and V2 of 6 female monkeys (Macaca nemestrina) made amblyopic by artificial strabismus or anisometropia in early life, as well as 2 visually normal female monkeys (Macaca nemestrina)...
July 25, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28732604/artificial-iris-implantation-in-various-iris-defects-and-lens-conditions
#13
Christian Mayer, Tamer Tandogan, Andrea E Hoffmann, Ramin Khoramnia
We describe 6 surgical techniques used to implant a silicone iris prosthesis: sector-shaped iris segments that require suturing, injector-assisted sulcus fixation, injector-assisted capsular bag fixation with an intraocular lens (IOL) and capsular tension ring, folded iris tissue implanted with a forceps and sutured to the sclera with a scleral-fixated IOL, "sandwich" or "backpack" implantation with an IOL, and open-sky implantation with a perforating keratoplasty. The results of the techniques performed in 51 patients are discussed...
June 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28720436/direct-measurement-of-pressure-independent-aqueous-humour-flow-using-iperfusion
#14
Michael Madekurozwa, Ester Reina-Torres, Darryl R Overby, Joseph M Sherwood
Reduction of intraocular pressure is the sole therapeutic target for glaucoma. Intraocular pressure is determined by the dynamics of aqueous humour secretion and outflow, which comprise several pressure-dependent and pressure-independent mechanisms. Accurately quantifying the components of aqueous humour dynamics is essential in understanding the pathology of glaucoma and the development of new treatments. To better characterise aqueous humour dynamics, we propose a method to directly measure pressure-independent aqueous humour flow...
September 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28718904/autologous-serum-eye-drops-and-enhanced-epithelial-healing-time-after-photorefractive-keratectomy
#15
Hanife Tuba Akcam, Metin Unlu, Emine Esra Karaca, Hulya Yazici, Bahri Aydin, Ahmet Murad Hondur
BACKGROUND: The aim of the study is to test whether use of autologous serum eye-drops can provide earlier epithelial healing following the application of photorefractive keratectomy. METHOD: Sixty patients (60 eyes) underwent photorefractive keratectomy for myopia. Thirty eyes received autologous serum drops (Study group) while 30 eyes received conventional artificial tears (Control group) after photorefractive keratectomy. An 8 mm epithelial opening was prepared with the application of 18 per cent alcohol for 20 seconds...
July 18, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28714189/esthesiometric-evaluation-of-corneal-analgesia-after-topical-application-of-1-morphine-sulfate-in-normal-horses
#16
Emma Gordon, Christy Sandquist, Christopher K Cebra, Jerry Heidel, Keith Poulsen, John W Schlipf
OBJECTIVE: To evaluate whether topical ocular application of 1% morphine sulfate would change corneal sensitivity and to identify the duration of action. ANIMAL STUDIED: Eight healthy adult horses. PROCEDURE: Corneal touch threshold (CTT) was measured in the center of one randomly selected eye of each horse by Cochet-Bonnet esthesiometer (Luneau Cochet-Bonnet Esthesiometer; Western Ophthalmics, Lynnwood, WA, USA). Immediately following baseline CTT measurement, 0...
July 17, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/28708527/artificially-extended-photoperiod-administered-to-pre-partum-mares-via-blue-light-to-a-single-eye-observations-on-gestation-length-foal-birth-weight-and-foal-hair-coat-at-birth
#17
Margaret B Nolan, Caroline M Walsh, Noelle Duff, Conor McCrarren, Ralph L Prendergast, Barbara A Murphy
In seasonally breeding animals, photoperiod perception is crucial for timing of important physiological events. In the horse, long day photoperiod influences the onset of ovulation and cyclicity, shedding of the heavier winter coat and the timing of parturition. In this compilation of studies, conducted across three breeding seasons and two countries, the impact of artificially extended day length was investigated on gestation length, foal birth weight and foal hair coat at birth. The light therapy was administered to pre-partum mares via mobile head worn masks which provided short wavelength blue light to a single eye...
June 9, 2017: Theriogenology
https://www.readbyqxmd.com/read/28700261/orbital-implant-infection-by-corynebacterium-amycolatum
#18
J Alvaro Toribio, Teresa Marrodán, Isabel Fernández-Natal
Corynebacterium amycolatum is a saprophyte gram-positive bacillus of the skin flora. It has been linked to diverse infections in immunocompromised patients and also of different types of prostheses. However, to our knowledge, there are no reports on its ability to produce ocular infections or to grow over alloplastic materials for orbital surgery. We present a case of orbital implant exposure including pure isolation of C. amycolatum. The patient was referred for discharge in his socket. After removal of the artificial eye, a large area of implant exposure and signs of chronic infection were observed...
July 12, 2017: Orbit
https://www.readbyqxmd.com/read/28689748/in-vivo-corneal-pulsation-in-relation-to-in-vivo-intraocular-pressure-and-corneal-biomechanics-assessed-in-vitro-an-animal-pilot-study
#19
Maja M Rogala, Monika E Danielewska, Agnieszka Antończyk, Zdzisław Kiełbowicz, Marta E Rogowska, Marta Kozuń, Jerzy Detyna, D Robert Iskander
The aim was to ascertain whether the characteristics of the corneal pulse (CP) measured in-vivo in a rabbit eye change after short-term artificial increase of intraocular pressure (IOP) and whether they correlate with corneal biomechanics assessed in-vitro. Eight New Zealand white rabbits were included in this study and were anesthetized. In-vivo experiments included simultaneous measurements of the CP signal, registered with a non-contact method, IOP, intra-arterial blood pressure, and blood pulse (BPL), at the baseline and short-term elevated IOP...
September 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28681902/integration-of-scheimpflug-based-corneal-tomography-and-biomechanical-assessments-for-enhancing-ectasia-detection
#20
Renato Ambrósio, Bernardo T Lopes, Fernando Faria-Correia, Marcella Q Salomão, Jens Bühren, Cynthia J Roberts, Ahmed Elsheikh, Riccardo Vinciguerra, Paolo Vinciguerra
PURPOSE: To present the Tomographic and Biomechanical Index (TBI), which combines Scheimpflugbased corneal tomography and biomechanics for enhancing ectasia detection. METHODS: Patients from different continents were retrospectively studied. The normal group included 1 eye randomly selected from 480 patients with normal corneas and the keratoconus group included 1 eye randomly selected from 204 patients with keratoconus. There were two groups: 72 ectatic eyes with no surgery from 94 patients with very asymmetric ectasia (VAE-E group) and the fellow eyes of these patients with normal topography (VAE-NT group)...
July 1, 2017: Journal of Refractive Surgery
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