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https://www.readbyqxmd.com/read/28640840/applying-artificial-intelligence-to-disease-staging-deep-learning-for-improved-staging-of-diabetic-retinopathy
#1
Hidenori Takahashi, Hironobu Tampo, Yusuke Arai, Yuji Inoue, Hidetoshi Kawashima
PURPOSE: Disease staging involves the assessment of disease severity or progression and is used for treatment selection. In diabetic retinopathy, disease staging using a wide area is more desirable than that using a limited area. We investigated if deep learning artificial intelligence (AI) could be used to grade diabetic retinopathy and determine treatment and prognosis. METHODS: The retrospective study analyzed 9,939 posterior pole photographs of 2,740 patients with diabetes...
2017: PloS One
https://www.readbyqxmd.com/read/28628379/visuomotor-behaviors-and-performance-in-a-dual-task-paradigm-with-and-without-vibrotactile-feedback-when-using-a-myoelectric-controlled-hand
#2
Eitan Raveh, Jason Friedman, Sigal Portnoy
Prosthesis users allocate visual attention to their prosthetic hand while performing activities of daily living (ADLs), due to absence of sensory feedback. Dual-task assignments present competition for visual attention and may affect the performance of ADLs. Vibrotactile feedback (VTF) is a frequently-used method to provide prosthesis users with tactile feedback. However, the effect of adding VTF on visual attention and performance in a motor dual-task paradigm has not been investigated. Our aim was to compare visual attention and performance during ADLs in a motor dual-task paradigm when using binary VTF and without using VTF...
June 19, 2017: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/28622318/characteristics-of-symptoms-experienced-by-persons-with-dry-eye-disease-while-driving-in-china
#3
Y Wang, H Lv, Y Liu, X Jiang, M Zhang, X Li, W Wang
PurposeTo assess the vision-related quality of life and self-reported driving performance of patients with dry eye disease (DED).Patients and methodsThe study was performed in the eye centre of Peking University Third Hospital, China. In total, 87 dry eye patients and 42 controls were enroled, including 49 patients without any treatment (group A), 38 patients treated with artificial tears (group B) and 42 controls without DED (group C). The participants had no eye disease other than DED. Scores of a vision-related quality-of-life questionnaire (Ocular Surface Disease Index (OSDI)), a daily life-related visual function questionnaire and a questionnaire about performance during driving were collected...
June 16, 2017: Eye
https://www.readbyqxmd.com/read/28617725/depth-profile-assessment-of-the-early-phase-deposition-of-lysozyme-on-soft-contact-lens-materials-using-a-novel-in-vitro-eye-model
#4
Han Qiao, Chau-Minh Phan, Hendrik Walther, Lakshman N Subbaraman, Lyndon Jones
OBJECTIVE: To characterize the location of fluorescently labeled lysozyme on commercial contact lenses (CLs) using an in vitro eye model that simulates tear volume, tear flow, air exposure, and mechanical wear. METHODS: One commercially available conventional hydrogel CL material (etafilcon A) and three silicone hydrogel CL materials (balafilcon A, lotrafilcon B, and senofilcon A) were evaluated in this study. The CLs were mounted on the in vitro eye model and exposed to artificial tear fluid containing fluorescein isothiocyanate (FITC)-labeled lysozyme for 2 and 10 hrs...
June 14, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28612282/probing-of-peripheral-blood-mononuclear-cells-anchoring-on-tnf-alpha-challenged-vascular-endothelia-in-an-in-vitro-model-of-the-retinal-microvascular
#5
Yuan Li, Yao Lu, Qiong Chen, Yuejun Kang, Ling Yu
Retinopathy is a complication of diabetes that affects the eyes; it stems from damage to the microvasculature of the retina and eventually compromises vision. The diagnosis of retinopathy is difficult to make because there are no early symptoms or warning signs. Dysfunction of the retina's microvascular networks is believed to be associated with inflammatory cytokines and tumor necrosis factor alpha (TNF-α). To investigate the effect of these cytokines, such as TNF-α, a polydimethylsiloxane (PDMS)/glass hydride microfluidic device reflecting the physiological structure of the retina's microvasculature was developed...
September 2017: Biomedical Microdevices
https://www.readbyqxmd.com/read/28606267/-comparison-of-two-kinds-of-artificial-tears-on-the-dry-eye-after-phacoemulsification
#6
R You, J Wang, Y Han, L J Liu, W Y Wang
Objective: To compare the curative effect of two different artificial tears on dry eye after phacoemulsification. Methods: Prospective randomized controlled clinical trial. From March to June in 2012, 102 patients (102 eyes) with age-related cataract were treated with phacoemulsification at Beijing Tongren Hospital, Capital University of Medical Sciences, and these eyes were randomly divided into blank group (group A ) 32 cases, treatment group 1 (group B) 35 cases and treatment group 2 (group C) 35 cases. Group A was treated with conventional antibiotics...
June 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28604053/are-fixations-in-static-natural-scenes-a-useful-predictor-of-attention-in-the-real-world
#7
Tom Foulsham, Alan Kingstone
Research investigating scene perception normally involves laboratory experiments using static images. Much has been learned about how observers look at pictures of the real world and the attentional mechanisms underlying this behaviour. However, the use of static, isolated pictures as a proxy for studying everyday attention in real environments has led to the criticism that such experiments are artificial. We report a new study that tests the extent to which the real world can be reduced to simpler laboratory stimuli...
June 2017: Canadian Journal of Experimental Psychology, Revue Canadienne de Psychologie Expérimentale
https://www.readbyqxmd.com/read/28601909/study-of-conjunctival-flora-in-anophthalmic-patients-influence-on-the-comfort-of-the-socket
#8
Alvaro Toribio, Teresa Marrodán, Isabel Fernández-Natal, Honorina Martínez-Blanco, Leandro Rodríguez-Aparicio, Miguel Á Ferrero
PURPOSE: To investigate the relationship between conjunctival flora and comfort of the socket in anophthalmic patients. METHODS: A cross-sectional clinical study including 60 patients with unilateral anophthalmia who wear a prosthetic eye. From each patient three microbiological samples were taken from the lower conjunctival sac (healthy eye, pre-prosthesis, and retro-prosthesis space of socket). The 180 samples obtained were cultured. Samples from a randomized subgroup of 29 patients were measured by spectrophotometry at 540 nm after 48 h of growth, to determine their microbial density (MD)...
June 10, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28599118/sensory-metrics-of-neuromechanical-trust
#9
William Softky, Criscillia Benford
Today digital sources supply a historically unprecedented component of human sensorimotor data, the consumption of which is correlated with poorly understood maladies such as Internet addiction disorder and Internet gaming disorder. Because both natural and digital sensorimotor data share common mathematical descriptions, one can quantify our informational sensorimotor needs using the signal processing metrics of entropy, noise, dimensionality, continuity, latency, and bandwidth. Such metrics describe in neutral terms the informational diet human brains require to self-calibrate, allowing individuals to maintain trusting relationships...
June 9, 2017: Neural Computation
https://www.readbyqxmd.com/read/28597519/feasibility-study-on-robot-assisted-retinal-vascular-bypass-surgery-in-an-ex%C3%A2-vivo-porcine-model
#10
Yi Qi Chen, Ji Wei Tao, Liang Li, Jian Bo Mao, Chen Ting Zhu, Ji Meng Lao, Yang Yang, Li-Jun Shen
PURPOSE: To describe a new robot-assisted surgical system for retinal vascular bypass surgery (RVBS) and to compare the success rate with freehand RVBS. METHODS: A robot-assisted system for retinal microsurgery was constructed to include two independent robotic arms. A 23-gauge light probe and an intraocular forceps were affixed to the arm end effectors to perform the intraocular manipulation. Harvested porcine eyes were introduced to be established animal models of closed-sky eyeballs after that pars plana vitrectomy using temporary keratoprosthesis was performed by a skilful surgeon...
June 9, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28595130/cyclotorsion-measurement-using-scleral-blood-vessels
#11
Aydın Kaya, Ali Seydi Keçeli, Ahmet Burak Can, Hasan Basri Çakmak
BACKGROUND AND OBJECTIVES: Measurements of the cyclotorsional movement of the eye are crucial in refractive surgery procedures. The planned surgery pattern may vary substantially during an operation because of the position and eye movements of the patient. Since these factors affect the outcome of an operation, eye registration methods are applied in order to compensate for errors. While the majority of applications are based on features of the iris, we propose a registration method which uses scleral blood vessels...
June 1, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28593605/online-webcam-based-eye-tracking-in-cognitive-science-a-first-look
#12
Kilian Semmelmann, Sarah Weigelt
Online experimentation is emerging in many areas of cognitive psychology as a viable alternative or supplement to classical in-lab experimentation. While performance- and reaction-time-based paradigms are covered in recent studies, one instrument of cognitive psychology has not received much attention up to now: eye tracking. In this study, we used JavaScript-based eye tracking algorithms recently made available by Papoutsaki et al. (International Joint Conference on Artificial Intelligence, 2016) together with consumer-grade webcams to investigate the potential of online eye tracking to benefit from the common advantages of online data conduction...
June 7, 2017: Behavior Research Methods
https://www.readbyqxmd.com/read/28592068/-reoperation-for-residual-aneurysm-of-coronary-anastomosis-after-bentall-procedure
#13
J R Xue, B Li, Y M Liu, T Bai, X D Pan, N N Liu, Z Qu, L Z Sun
Objective: To introduce a new operative method for residual aneurysm of coronary anastomosis after Bentall procedure. Methods: Between March 2011 and December 2012, six patients in Beijing Anzhen Hospital with residual aneurysm of coronary anastomosis (CT showed goldfish eye sign at the openings of coronary) after Bentall procedure underwent the operation of concentric circular patch procedure under cardiopulmonary bypass. Femoral artery, right atrium and upper right pulmonary artery cannulation were used for cardiopulmonary bypass, and the artificial vessel was transected after cardiac arrest...
May 30, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28591156/dark-eyes-in-female-sand-gobies-indicate-readiness-to-spawn
#14
Karin H Olsson, Sandra Johansson, Eva-Lotta Blom, Kai Lindström, Ola Svensson, Helen Nilsson Sköld, Charlotta Kvarnemo
In animals, colorful and conspicuous ornaments enhance individual attractiveness to potential mates, but are typically tempered by natural selection for crypsis and predator protection. In species where males compete for females, this can lead to highly ornamented males competing for mating opportunities with choosy females, and vice versa. However, even where males compete for mating opportunities, females may exhibit conspicuous displays. These female displays are often poorly understood and it may be unclear whether they declare mating intent, signal intrasexual aggression or form a target for male mate preference...
2017: PloS One
https://www.readbyqxmd.com/read/28589679/self-regulating-iris-based-on-light-actuated-liquid-crystal-elastomer
#15
Hao Zeng, Owies M Wani, Piotr Wasylczyk, Radosław Kaczmarek, Arri Priimagi
The iris, found in many animal species, is a biological tissue that can change the aperture (pupil) size to regulate light transmission into the eye in response to varying illumination conditions. The self-regulation of the eye lies behind its autofocusing ability and large dynamic range, rendering it the ultimate "imaging device" and a continuous source of inspiration in science. In optical imaging devices, adjustable apertures play a vital role as they control the light exposure, the depth of field, and optical aberrations of the systems...
June 7, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28586930/-mid-and-longterm-experiences-with-the-boston-keratoprosthesis-the-cologne-and-salzburg-perspective
#16
Friederike Schaub, Björn O Bachmann, Orang Seyeddain, Sarah Moussa, Herbert A Reitsamer, Claus Cursiefen
Background Eyes with severe corneal opacifications and insufficient prognosis for high-risk corneal transplantation can be considered for the implantation of a Boston-keratoprosthesis. Since 2013, this technique of "artificial" corneal replacement is provided to high-risk eyes at the Department of Ophthalmology, University of Cologne and for 9 years at the University of Salzburg. In the meantime, a type I Boston keratoprosthesis (BI-KPro) has been implanted in 24 eyes in Cologne and in 28 eyes in Salzburg. Methods In this article, results and complications according to BI-KPro are discussed, both from the literature in PubMed, as well as from our own experiences...
June 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28586929/-keratoprosthesis-with-biological-haptic-the-d%C3%A3-sseldorf-offenburg-experience-with-osteo-odonto-and-tibia-keratoprosthesis
#17
Gerd Geerling, Konrad Hille
In severe ocular surface disease with limbal stem cell deficiency associated with severe dry eye, penetrating keratoplasty is likely to fail. In these cases, and provided the posterior segment is normal, keratoprosthesis surgery (KPro) can achieve visual rehabilitation. In KPros with an autologous biological haptic, a bone-tooth-complex (osteo-odonto-keratoprothesis, OOKPro) or a piece of tibial cortex (tibia-keratoprosthesis, TKPro) is used to carry a PMMA cylinder. This construct can successfully be implanted even in severely dry eyes and in those with autoimmune disease, in which other KPro designs frequently fail...
June 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28584422/an-innovative-and-simple-approach-to-fabricate-a-hollow-ocular-prosthesis-with-functional-lubricant-reservoir-a-solution-to-artificial-eye-comfort
#18
Aditya Anil Kavlekar, Meena Ajay Aras, Vidya Chitre
The loss of an eye is an emotional and psychological setback to the patient. An ocular prosthesis is created to restore the lost anatomical structure and to correct the cosmetic defect. The tear reflexes do not function at optimal levels in anophthalmic sockets which make prosthesis wear uncomfortable. This case report presents an innovative hollow ocular prosthesis with functional lubricant reservoir which upon normal blinking would draw the lubricant from the reservoir through an exit hole which spreads over the prosthesis allowing a comfortable and long duration of prosthesis wear...
April 2017: Journal of Indian Prosthodontic Society
https://www.readbyqxmd.com/read/28576202/effect-of-artificial-anisometropia-in-dominant-and-nondominant-eyes-on-stereoacuity
#19
Reza Nabie, Dima Andalib, Safieh Amir-Aslanzadeh, Hasan Khojasteh
OBJECTIVE: To evaluate the effect of artificial anisometropia in dominant and nondominant eyes on stereoacuity. METHODS: In this descriptive analytic study, 60 healthy adult volunteers 18-37 years of age (mean age: 25.58 years) without any ocular disease were enrolled at Tabriz Nikookari eye hospital over a 1-year period. Anisometropia (unilateral myopia) was induced by placing trial lenses over the dominant and nondominant eyes in 1-diopter (D) increments ranging from 1 to 3 D...
June 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28574137/iris-reconstruction-using-artificial-iris-prosthesis-for-management-of-aniridia
#20
Yehia S Mostafa, Amr A Osman, Dina H Hassanein, Ashraf M Zeid, Ahmed M Sherif
PURPOSE: To discuss the limitations and benefits of the BrightOcular prosthetic artificial iris device in management of aniridia associated with aphakia or cataract. METHODS: This is a retrospective study including 5 eyes of 4 patients who underwent implantation of the BrightOcular iris prosthesis (Stellar Devices) for total or partial aniridia. The cases included 2 eyes of 1 patient with congenital aniridia associated with congenital cataract and 3 eyes with traumatic aniridia: 1 with subluxated cataractous lens and 2 with aphakia...
May 27, 2017: European Journal of Ophthalmology
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