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High intensity interval training hypoxia

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https://www.readbyqxmd.com/read/29696212/feasibility-of-high-intensity-interval-training-with-hyperoxia-vs-intermittent-hyperoxia-and-hypoxia-in-cancer-patients-undergoing-chemotherapy-study-protocol-of-a-randomized-controlled-trial
#1
Moritz Schumann, Holger Schulz, Anthony C Hackney, Wilhelm Bloch
Exercise has been well demonstrated to potentially reduce chemotherapy-induced side effects and possibly aid slowing down tumor growth in cancer patients but exercise training adherence is typically low. Thus, training regimens which are perceived less strenuous but do not compromise the training-induced beneficial adaptations will help to increase adherence to exercise and reduce attrition. This 4-armed study aims to investigate the effects of high intensity interval training (HIIT) in hyperoxia versus intermittent hyperoxia and hypoxia in cancer patients undergoing chemotherapy...
December 2017: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/29472870/high-intensity-interval-training-in-normobaric-hypoxia-leads-to-greater-body-fat-loss-in-overweight-obese-women-than-high-intensity-interval-training-in-normoxia
#2
Alba Camacho-Cardenosa, Marta Camacho-Cardenosa, Martin Burtscher, Ismael Martínez-Guardado, Rafael Timon, Javier Brazo-Sayavera, Guillermo Olcina
A moderate hypoxic stimulus is considered a promising therapeutic modality for several pathological states including obesity. There is scientific evidence suggesting that when hypoxia and physical activity are combined, they could provide benefits for the obese population. The aim of the present study was to investigate if exposure to hypoxia combined with two different protocols of high-intensity interval exercise in overweight/obese women was more effective compared with exercise in normoxia. Study participants included 82 overweight/obese women, who started a 12 week program of 36 sessions, and were randomly divided into four groups: (1) aerobic interval training in hypoxia (AitH; FiO2 = 17...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29423544/high-intensity-interval-training-in-hypoxia-does-not-affect-muscle-hif-responses-to-acute-hypoxia-in-humans
#3
Stefan De Smet, Gommaar D'Hulst, Chiel Poffé, Ruud Van Thienen, Emanuele Berardi, Peter Hespel
PURPOSE: The myocellular response to hypoxia is primarily regulated by hypoxia-inducible factors (HIFs). HIFs thus conceivably are implicated in muscular adaptation to altitude training. Therefore, we investigated the effect of hypoxic versus normoxic training during a period of prolonged hypoxia ('living high') on muscle HIF activation during acute ischaemia. METHODS: Ten young male volunteers lived in normobaric hypoxia for 5 weeks (5 days per week, ~ 15.5 h per day, Fi O2 : 16...
April 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28763443/intermittent-hypoxic-training-improves-anaerobic-performance-in-competitive-swimmers-when-implemented-into-a-direct-competition-mesocycle
#4
RANDOMIZED CONTROLLED TRIAL
Miłosz Czuba, Robert Wilk, Jakub Karpiński, Małgorzata Chalimoniuk, Adam Zajac, Józef Langfort
The main objective of this research was to evaluate the efficacy of intermittent hypoxic training (IHT) on anaerobic and aerobic capacity and swimming performance in well-trained swimmers. Sixteen male swimmers were randomly divided into a hypoxia (H) group (n = 8), which trained in a normobaric hypoxia environment, and a control (C) group (n = 8), which exercised under normoxic conditions. However, one participant left the study without explanation. During the experiment group H trained on land twice per week in simulated hypoxia (FiO2 = 15...
2017: PloS One
https://www.readbyqxmd.com/read/28706859/role-of-metabolic-stress-for-enhancing-muscle-adaptations-practical-applications
#5
REVIEW
Marcelo Conrado de Freitas, Jose Gerosa-Neto, Nelo Eidy Zanchi, Fabio Santos Lira, Fabrício Eduardo Rossi
Metabolic stress is a physiological process that occurs during exercise in response to low energy that leads to metabolite accumulation [lactate, phosphate inorganic (Pi) and ions of hydrogen (H+)] in muscle cells. Traditional exercise protocol (i.e., Resistance training) has an important impact on the increase of metabolite accumulation, which influences hormonal release, hypoxia, reactive oxygen species (ROS) production and cell swelling. Changes in acute exercise routines, such as intensity, volume and rest between sets, are determinants for the magnitude of metabolic stress, furthermore, different types of training, such as low-intensity resistance training plus blood flow restriction and high intensity interval training, could be used to maximize metabolic stress during exercise...
June 26, 2017: World Journal of Methodology
https://www.readbyqxmd.com/read/28646182/high-intensity-interval-training-improves-mitochondrial-function-and-suppresses-thrombin-generation-in-platelets-undergoing-hypoxic-stress
#6
Li-Hua Wu, Shao-Chiang Chang, Tieh-Cheng Fu, Ching-Hui Huang, Jong-Shyan Wang
This study elucidates how high-intensity interval training (HIT) and moderate-intensity continuous training (MCT) affect mitochondrial functionality and thrombin generation (TG) in platelets following hypoxic exercise (HE, 100 W under 12% O2 for 30 min). Forty-five healthy sedentary males were randomized to engage either HIT (3-minute intervals at 40% and 80%VO2max, n = 15) or MCT (sustained 60%VO2max, n = 15) for 30 minutes/day, 5 days/week for 6 weeks, or to a control group (CTL, n = 15) that did not received exercise intervention...
June 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28620311/physiological-adaptations-to-hypoxic-vs-normoxic-training-during-intermittent-living-high
#7
Stefan De Smet, Paul van Herpt, Gommaar D'Hulst, Ruud Van Thienen, Marc Van Leemputte, Peter Hespel
In the setting of "living high," it is unclear whether high-intensity interval training (HIIT) should be performed "low" or "high" to stimulate muscular and performance adaptations. Therefore, 10 physically active males participated in a 5-week "live high-train low or high" program (TR), whilst eight subjects were not engaged in any altitude or training intervention (CON). Five days per week (~15.5 h per day), TR was exposed to normobaric hypoxia simulating progressively increasing altitude of ~2,000-3,250 m...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28479953/effects-of-simulated-altitude-on-maximal-oxygen-uptake-and-inspiratory-fitness
#8
Nicole C Biggs, Benjamin S England, Nicole J Turcotte, Melissa R Cook, Alyne L Williams
Aerobic exercise at altitude has shown an increase in maximal oxygen uptake. Similar effects have been replicated by way of simulated altitude training, which have influenced various advances in the field of exercise science. Elevation Training Masks© (ETM) claim to stimulate cardiorespiratory fitness improvements similar to training at altitude, however, there is little research to support this claim. The purpose of this study was to research the effect that a hypoxia-inducing mask would have on cardiorespiratory fitness and pulmonary function through the use of a high intensity interval training (HIIT) running program...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/28386234/high-intensity-interval-training-in-normobaric-hypoxia-improves-cardiorespiratory-fitness-in-overweight-chinese-young-women
#9
Zhaowei Kong, Qingde Shi, Jinlei Nie, Tomas K Tong, Lili Song, Longyan Yi, Yang Hu
Previous studies have investigated the effects of high-intensity interval training (HIIT) on cardiorespiratory fitness and body composition in overweight populations. However, the additive effect of HIIT and hypoxia on health parameters is not clear. This study compared the effects of HIIT under hypoxic conditions on cardiometabolic function with that under normoxia in overweight Chinese young women. Methods: A double-blind randomized controlled experimental design was applied. Twenty-four sedentary overweight Chinese young women (weight: 68...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28368957/impact-of-endurance-exercise-in-hypoxia-on-muscle-damage-inflammatory-and-performance-responses
#10
Daichi Sumi, Chihiro Kojima, Kazushige Goto
Sumi, D, Kojima, C, and Goto, K. Impact of endurance exercise in hypoxia on muscle damage, inflammatory and performance responses. J Strength Cond Res 32(4): 1053-1062, 2018-This study evaluated muscle damage and inflammatory and performance responses after high-intensity endurance exercise in moderate hypoxia among endurance athletes. Nine trained endurance athletes completed 2 different trials on different days: exercise under moderate hypoxia (H trial, FiO2 = 14.5%) and normoxia (N trial, FiO2 = 20.9%). They performed interval exercises (10 × 3-minute running at 95% of V[Combining Dot Above]O2max with 60-second of active rest at 60% of V[Combining Dot Above]O2max) followed by 30-minute of continuous running at 85% of V[Combining Dot Above]O2max under either hypoxic or normoxic conditions...
April 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27761657/high-intensity-interval-training-enhances-mobilization-functionality-of-endothelial-progenitor-cells-and-depressed-shedding-of-vascular-endothelial-cells-undergoing-hypoxia
#11
RANDOMIZED CONTROLLED TRIAL
Hsing-Hua Tsai, Chin-Pu Lin, Yi-Hui Lin, Chih-Chin Hsu, Jong-Shyan Wang
PURPOSE: Exercise training improves endothelium-dependent vasodilation, whereas hypoxic stress causes vascular endothelial dysfunction. Monocyte-derived endothelial progenitor cells (Mon-EPCs) contribute to vascular repair process by differentiating into endothelial cells. This study investigates how high-intensity interval (HIT) and moderate-intensity continuous (MCT) exercise training affect circulating Mon-EPC levels and EPC functionality under hypoxic condition. METHODS: Sixty healthy sedentary males were randomized to engage in either HIT (3-min intervals at 40 and 80 % VO2max for five repetitions, n = 20) or MCT (sustained 60 % VO2max, n = 20) for 30 min/day, 5 days/week for 6 weeks, or to a control group (CTL) that did not received exercise intervention (n = 20)...
December 2016: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/27731374/exercise-training-alleviates-hypoxia-induced-mitochondrial-dysfunction-in-the-lymphocytes-of-sedentary-males
#12
RANDOMIZED CONTROLLED TRIAL
Hsing-Hua Tsai, Shao-Chiang Chang, Cheng-Hsien Chou, Tzu-Pin Weng, Chih-Chin Hsu, Jong-Shyan Wang
This study elucidates how interval and continuous exercise regimens affect the mitochondrial functionality of lymphocytes under hypoxic stress. Sixty healthy sedentary males were randomly assigned to engage in either high-intensity interval training (HIIT, 3 min intervals at 80% and 40% VO2max , n = 20) or moderate-intensity continuous training (MICT, sustained 60% VO2max , n = 20) for 30 min/day, 5 days/week for 6 weeks or were assigned to a control group that did not receive exercise intervention (n = 20)...
October 12, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27274656/cardiorespiratory-effects-of-one-legged-high-intensity-interval-training-in-normoxia-and-hypoxia-a-pilot-study
#13
Verena Menz, Mona Semsch, Florian Mosbach, Martin Burtscher
A higher-than-average maximal oxygen consumption (VO2max), is closely associated with decreased morbidity and mortality and improved quality of life and acts as a marker of cardiorespiratory fitness. Although there is no consensus about an optimal training method to enhance VO2max, nevertheless training of small muscle groups and repeated exposure to hypoxia seem to be promising approaches. Therefore, this study was aimed at gaining innovative insights into the effects of small muscle group training in normoxia and hypoxia...
June 2016: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/26566220/effects-of-high-intensity-interval-training-on-pregnant-rats-and-the-placenta-heart-and-liver-of-their-fetuses
#14
Nils Thomas Songstad, Knut-Helge Frostmo Kaspersen, Anne Dragøy Hafstad, Purusotam Basnet, Kirsti Ytrehus, Ganesh Acharya
OBJECTIVE: To investigate the effects of high intensity interval training (HIIT) on the maternal heart, fetuses and placentas of pregnant rats. METHODS: Female Sprague-Dawley rats were randomly assigned to HIIT or sedentary control groups. The HIIT group was trained for 6 weeks with 10 bouts of high intensity uphill running on a treadmill for four minutes (at 85-90% of maximal oxygen consumption) for five days/week. After three weeks of HIIT, rats were mated. After six weeks (gestational day 20 in pregnant rats), echocardiography was performed to evaluate maternal cardiac function...
2015: PloS One
https://www.readbyqxmd.com/read/25946570/aging-tolerance-to-high-altitude-and-cardiorespiratory-response-to-hypoxia
#15
Jean-Paul Richalet, François J Lhuissier
Richalet, Jean-Paul, and François J. Lhuissier. Aging, tolerance to high altitude, and cardiorespiratory response to hypoxia. High Alt Med Biol. 16:117-124, 2015.--It is generally accepted that aging is rather protective, at least at moderate altitude. Some anecdotal reports even mention successful ascent of peaks over 8000 m and even Everest by elderly people. However, very few studies have explored the influence of aging on tolerance to high altitude and prevalence of acute high altitude related diseases, taking into account all confounding factors such as speed of ascent, altitude reached, sex, training status, and chemo-responsiveness...
June 2015: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/25944456/changes-in-running-performance-after-four-weeks-of-interval-hypoxic-training-in-australian-footballers-a-single-blind-placebo-controlled-study
#16
Blake D McLean, Paul J Tofari, Christopher J Gore, Justin G Kemp
There is a paucity of data examining the impact of high-intensity interval hypoxic training (IHT) on intermittent running performance. This study assessed the effects of IHT on 17 amateur Australian Footballers, who completed 8 interval treadmill running sessions (IHT [FIO2 = 15.1%] or PLACEBO) over 4 weeks, in addition to normoxic football (2 per week) and resistance (2 per week) training sessions. To match relative training intensity, absolute IHT intensity reduced by 6% of normoxic vV[Combining Dot Above]O2peak compared with PLACEBO...
November 2015: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/25803693/high-intensity-interval-and-endurance-training-have-opposing-effects-on-markers-of-heart-failure-and-cardiac-remodeling-in-hypertensive-rats
#17
Tanya M Holloway, Darin Bloemberg, Mayne L da Silva, Jeremy A Simpson, Joe Quadrilatero, Lawrence L Spriet
There has been re-emerging interest and significant work dedicated to investigating the metabolic effects of high intensity interval training (HIIT) in recent years. HIIT is considered to be a time efficient alternative to classic endurance training (ET) that elicits similar metabolic responses in skeletal muscle. However, there is a lack of information on the impact of HIIT on cardiac muscle in disease. Therefore, we determined the efficacy of ET and HIIT to alter cardiac muscle characteristics involved in the development of diastolic dysfunction, such as ventricular hypertrophy, fibrosis and angiogenesis, in a well-established rodent model of hypertension-induced heart failure before the development of overt heart failure...
2015: PloS One
https://www.readbyqxmd.com/read/25435785/the-effects-of-hypobaric-hypoxia-on-erythropoiesis-maximal-oxygen-uptake-and-energy-cost-of-exercise-under-normoxia-in-elite-biathletes
#18
Milosz Czuba, Adam Maszczyk, Dagmara Gerasimuk, Robert Roczniok, Olga Fidos-Czuba, Adam Zając, Artur Gołaś, Aleksandra Mostowik, Jozef Langfort
The aim of the present study was to evaluate the effects of 3 weeks altitude training according to the HiHiLo (live high-base train high-interval train low) procedure as described by Chapman et al. (1998), on erythropoiesis, maximal oxygen uptake and energy cost of exercise under normoxia in elite biathletes. Fifteen male elite biathletes randomly divided into an experimental (H) group (n = 7; age 27.1 ± 4.6 years; maximal oxygen uptake (VO2max) 66.9 ± 3.3 ml·kg(-1)·min(-1); body height (BH) 1.81 ± 0.06 m; body mass (BM) 73...
December 2014: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/24849544/application-of-live-low-train-high-for-enhancing-normoxic-exercise-performance-in-team-sport-athletes
#19
REVIEW
Blake D McLean, Christopher J Gore, Justin Kemp
BACKGROUND AND OBJECTIVE: Hypoxic training techniques are increasingly used by athletes in an attempt to improve performance in normoxic environments. The 'live low-train high (LLTH)' model of hypoxic training may be of particular interest to athletes because LLTH protocols generally involve shorter hypoxic exposures (approximately two to five sessions per week of <3 h) than other traditional hypoxic training techniques (e.g., live high-train high or live high-train low). However, the methods employed in LLTH studies to date vary greatly with respect to exposure times, training intensities, training modalities, degrees of hypoxia and performance outcomes assessed...
September 2014: Sports Medicine
https://www.readbyqxmd.com/read/24511346/the-effects-of-high-intensity-interval-training-in-normobaric-hypoxia-on-aerobic-capacity-in-basketball-players
#20
Miłosz Czuba, Adam Zając, Adam Maszczyk, Robert Roczniok, Stanisław Poprzęcki, Wiesław Garbaciak, Tomasz Zając
The aim of the present study was to evaluate the efficacy of 3-week high intensity interval training in normobaric hypoxia (IHT) on aerobic capacity in basketball players. Twelve male well trained basketball players, randomly divided into a hypoxia (H) group (n=6; age: 22±1.6 years; VO2max: 52.6±3.9 ml/kg/min; body height - BH: 188.8±6.1 cm; body mass - BM: 83.9±7.2 kg; % of body fat - FAT%: 11.2±3.1%), and a control (C) group (n=6; age: 22±2.4 years; VO2max: 53.0±5.2 ml/kg/min; BH: 194.3 ± 6.6 cm; BM: 99...
December 18, 2013: Journal of Human Kinetics
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