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High intensity interval training hypoxia

Hsing-Hua Tsai, Chin-Pu Lin, Yi-Hui Lin, Chih-Chin Hsu, Jong-Shyan Wang
PURPOSE: Exercise training improves endothelium-dependent vasodilation, whereas hypoxic stress causes vascular endothelial dysfunction. Monocyte-derived endothelial progenitor cells (Mon-EPCs) contribute to vascular repair process by differentiating into endothelial cells. This study investigates how high-intensity interval (HIT) and moderate-intensity continuous (MCT) exercise training affect circulating Mon-EPC levels and EPC functionality under hypoxic condition. METHODS: Sixty healthy sedentary males were randomized to engage in either HIT (3-min intervals at 40 and 80 % VO2max for five repetitions, n = 20) or MCT (sustained 60 % VO2max, n = 20) for 30 min/day, 5 days/week for 6 weeks, or to a control group (CTL) that did not received exercise intervention (n = 20)...
December 2016: European Journal of Applied Physiology
Hsing-Hua Tsai, Shao-Chiang Chang, Cheng-Hsien Chou, Tzu-Pin Weng, Chih-Chin Hsu, Jong-Shyan Wang
This study elucidates how interval and continuous exercise regimens affect the mitochondrial functionality of lymphocytes under hypoxic stress. Sixty healthy sedentary males were randomly assigned to engage in either high-intensity interval training (HIIT, 3 min intervals at 80% and 40% VO2max, n = 20) or moderate-intensity continuous training (MICT, sustained 60% VO2max, n = 20) for 30 min/day, 5 days/week for 6 weeks or were assigned to a control group that did not receive exercise intervention (n = 20)...
October 12, 2016: Scientific Reports
Verena Menz, Mona Semsch, Florian Mosbach, Martin Burtscher
A higher-than-average maximal oxygen consumption (VO2max), is closely associated with decreased morbidity and mortality and improved quality of life and acts as a marker of cardiorespiratory fitness. Although there is no consensus about an optimal training method to enhance VO2max, nevertheless training of small muscle groups and repeated exposure to hypoxia seem to be promising approaches. Therefore, this study was aimed at gaining innovative insights into the effects of small muscle group training in normoxia and hypoxia...
June 2016: Journal of Sports Science & Medicine
Nils Thomas Songstad, Knut-Helge Frostmo Kaspersen, Anne Dragøy Hafstad, Purusotam Basnet, Kirsti Ytrehus, Ganesh Acharya
OBJECTIVE: To investigate the effects of high intensity interval training (HIIT) on the maternal heart, fetuses and placentas of pregnant rats. METHODS: Female Sprague-Dawley rats were randomly assigned to HIIT or sedentary control groups. The HIIT group was trained for 6 weeks with 10 bouts of high intensity uphill running on a treadmill for four minutes (at 85-90% of maximal oxygen consumption) for five days/week. After three weeks of HIIT, rats were mated. After six weeks (gestational day 20 in pregnant rats), echocardiography was performed to evaluate maternal cardiac function...
2015: PloS One
Jean-Paul Richalet, François J Lhuissier
Richalet, Jean-Paul, and François J. Lhuissier. Aging, tolerance to high altitude, and cardiorespiratory response to hypoxia. High Alt Med Biol. 16:117-124, 2015.--It is generally accepted that aging is rather protective, at least at moderate altitude. Some anecdotal reports even mention successful ascent of peaks over 8000 m and even Everest by elderly people. However, very few studies have explored the influence of aging on tolerance to high altitude and prevalence of acute high altitude related diseases, taking into account all confounding factors such as speed of ascent, altitude reached, sex, training status, and chemo-responsiveness...
June 2015: High Altitude Medicine & Biology
Blake D McLean, Paul J Tofari, Christopher J Gore, Justin G Kemp
There is a paucity of data examining the impact of high-intensity interval hypoxic training (IHT) on intermittent running performance. This study assessed the effects of IHT on 17 amateur Australian Footballers, who completed 8 interval treadmill running sessions (IHT [FIO2 = 15.1%] or PLACEBO) over 4 weeks, in addition to normoxic football (2 per week) and resistance (2 per week) training sessions. To match relative training intensity, absolute IHT intensity reduced by 6% of normoxic vV[Combining Dot Above]O2peak compared with PLACEBO...
November 2015: Journal of Strength and Conditioning Research
Tanya M Holloway, Darin Bloemberg, Mayne L da Silva, Jeremy A Simpson, Joe Quadrilatero, Lawrence L Spriet
There has been re-emerging interest and significant work dedicated to investigating the metabolic effects of high intensity interval training (HIIT) in recent years. HIIT is considered to be a time efficient alternative to classic endurance training (ET) that elicits similar metabolic responses in skeletal muscle. However, there is a lack of information on the impact of HIIT on cardiac muscle in disease. Therefore, we determined the efficacy of ET and HIIT to alter cardiac muscle characteristics involved in the development of diastolic dysfunction, such as ventricular hypertrophy, fibrosis and angiogenesis, in a well-established rodent model of hypertension-induced heart failure before the development of overt heart failure...
2015: PloS One
Milosz Czuba, Adam Maszczyk, Dagmara Gerasimuk, Robert Roczniok, Olga Fidos-Czuba, Adam Zając, Artur Gołaś, Aleksandra Mostowik, Jozef Langfort
The aim of the present study was to evaluate the effects of 3 weeks altitude training according to the HiHiLo (live high-base train high-interval train low) procedure as described by Chapman et al. (1998), on erythropoiesis, maximal oxygen uptake and energy cost of exercise under normoxia in elite biathletes. Fifteen male elite biathletes randomly divided into an experimental (H) group (n = 7; age 27.1 ± 4.6 years; maximal oxygen uptake (VO2max) 66.9 ± 3.3 ml·kg(-1)·min(-1); body height (BH) 1.81 ± 0.06 m; body mass (BM) 73...
December 2014: Journal of Sports Science & Medicine
Blake D McLean, Christopher J Gore, Justin Kemp
BACKGROUND AND OBJECTIVE: Hypoxic training techniques are increasingly used by athletes in an attempt to improve performance in normoxic environments. The 'live low-train high (LLTH)' model of hypoxic training may be of particular interest to athletes because LLTH protocols generally involve shorter hypoxic exposures (approximately two to five sessions per week of <3 h) than other traditional hypoxic training techniques (e.g., live high-train high or live high-train low). However, the methods employed in LLTH studies to date vary greatly with respect to exposure times, training intensities, training modalities, degrees of hypoxia and performance outcomes assessed...
September 2014: Sports Medicine
Miłosz Czuba, Adam Zając, Adam Maszczyk, Robert Roczniok, Stanisław Poprzęcki, Wiesław Garbaciak, Tomasz Zając
The aim of the present study was to evaluate the efficacy of 3-week high intensity interval training in normobaric hypoxia (IHT) on aerobic capacity in basketball players. Twelve male well trained basketball players, randomly divided into a hypoxia (H) group (n=6; age: 22±1.6 years; VO2max: 52.6±3.9 ml/kg/min; body height - BH: 188.8±6.1 cm; body mass - BM: 83.9±7.2 kg; % of body fat - FAT%: 11.2±3.1%), and a control (C) group (n=6; age: 22±2.4 years; VO2max: 53.0±5.2 ml/kg/min; BH: 194.3 ± 6.6 cm; BM: 99...
December 18, 2013: Journal of Human Kinetics
Raphaël Faiss, Olivier Girard, Grégoire P Millet
Over the past two decades, intermittent hypoxic training (IHT), that is, a method where athletes live at or near sea level but train under hypoxic conditions, has gained unprecedented popularity. By adding the stress of hypoxia during 'aerobic' or 'anaerobic' interval training, it is believed that IHT would potentiate greater performance improvements compared to similar training at sea level. A thorough analysis of studies including IHT, however, leads to strikingly poor benefits for sea-level performance improvement, compared to the same training method performed in normoxia...
December 2013: British Journal of Sports Medicine
Tzu-Pin Weng, Shu-Chun Huang, Yu-Fen Chuang, Jong-Shyan Wang
Exercise is linked with the type/intensity-dependent adaptive immune responses, whereas hypoxic stress facilitates the programmed death of CD4 lymphocytes. This study investigated how high intensity-interval (HIT) and moderate intensity-continuous (MCT) exercise training influence hypoxia-induced apoptosis and autophagy of CD4 lymphocytes in sedentary men. Thirty healthy sedentary males were randomized to engage either HIT (3-minute intervals at 40% and 80%VO2max, n=10) or MCT (sustained 60%VO2max, n=10) for 30 minutes/day, 5 days/week for 5 weeks, or to a control group that did not received exercise intervention (CTL, n=10)...
2013: PloS One
(no author information available yet)
We undertook the comprehensive examination and treatment with the interval hypoxic training and enteral oxygen therapy of 285 patients presenting with mild and moderately severe bronchial asthma. The study has demonstrated the improvement of oxygen supply to various organs at all stages of its mass transfer and the enhanced oxygen consumption by the tissue. These effects promoted normalization of the function of the respiratory system, characteristics of the exhaled air condensate, the state of the pro-oxidant and anti-oxidant systems...
July 2012: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
François Billaut, Christopher J Gore, Robert J Aughey
Field-based team sport matches are composed of short, high-intensity efforts, interspersed with intervals of rest or submaximal exercise, repeated over a period of 60-120 minutes. Matches may also be played at moderate altitude where the lower oxygen partial pressure exerts a detrimental effect on performance. To enhance run-based performance, team-sport athletes use varied training strategies focusing on different aspects of team-sport physiology, including aerobic, sprint, repeated-sprint and resistance training...
September 1, 2012: Sports Medicine
S C Dennis, T D Noakes
Interest in rises in oxygen consumption (VO2) with increasing exercise intensity largely originate from the work of Hill and colleagues in the 1920s. Their studies led to a belief that cardiac output and VO2 'plateau' at increasing work rates and that muscle hypoxia leads to fatigue. Hence, it was assumed that the primary benefit of exercise training is to increase muscle oxidative capacity and that the greatest benefit of training would occur at work rates around the 'anaerobic threshold'. In this paper, we question whether working muscles become hypoxic at high work rates...
January 1998: Journal of Sports Sciences
Daniel J McCann, Brian K Higginson
Recent reviews of how training affects running performance have indicated, to varying degrees, that running economy (RE) is a determinant of running performance. However, the literature suggests that the relationship between training-induced changes in biomechanics and RE is still largely unknown. While there is some evidence that high intensity interval training, plyometrics, and altitude/hypoxia training can improve economy, it remains unclear how these improvements are mediated. In addition, although it is clear from the literature that meaningful differences in RE exist among runners, the causes for the inherent differences are not clear...
May 2008: Current Sports Medicine Reports
Rodolfo Demo, Daniel Senestrari, Julio E Ferreyra
ANTECEDENTS: With the same intensity of sub-maximum effort, the concentration of serum (LS) or muscular lactate is higher in Hypoxia conditions, or exercise at an altitude without acclimation, in relation with normoxia or at sea level (MSL). The highest level of lactate after fatigue or in a test of strict anaerobic condition, would not be modified when altitude changes without previous acclimation. OBJECTIVE: To abtain local data about the magnitude of the affect in SL of a effective altitude at 1,700 meters without acclimation, as a parameter of aerobic performance of young soccer players of our environment who live and train at sea level...
2007: Revista de la Facultad de Ciencias Médicas
Frank Suhr, Klara Brixius, Markus de Marées, Birgit Bölck, Heinz Kleinöder, Silvia Achtzehn, Wilhelm Bloch, Joachim Mester
This study aimed to investigate the biological response to hypoxia as a stimulus, as well as exercise- and vibration-induced shear stress, which is known to induce angiogenesis. Twelve male cyclists (27.8 +/- 5.4 yr) participated in this study. Each subject completed four cycle training sessions under normal conditions (NC) without vibration, NC with vibration, normobaric hypoxic conditions (HC) without vibration, and HC with vibration. Each session lasted 90 min, and sessions were held at weekly intervals in a randomized order...
August 2007: Journal of Applied Physiology
Belle Roels, Grégoire P Millet, Christophe J L Marcoux, Olivier Coste, David J Bentley, Robin B Candau
PURPOSE: The aim of this study was to test the hypothesis that intermittent hypoxic interval training improves sea level cycling performance more than equivalent training in hypoxia or normoxia. METHODS: Thirty-three well-trained cyclists and triathletes (25.9 +/- 2.7 yr, VO(2max) 66.1 +/- 6.1 mL.min(-1).kg(-1)) were divided into three groups: intermittent hypoxic (IHT, N = 11, P(I)O(2) of 100 mm Hg), intermittent hypoxic interval training (IHIT, N = 11) and normoxia (Nor, N = 11, P(I)O(2) of 160 mm Hg) and completed a 7-wk training program, consisting of two high-intensity (100 or 90% relative peak power output) interval training sessions each week...
January 2005: Medicine and Science in Sports and Exercise
L Bernardi
Interval hypoxic training (IHT) is a technique developed in the former Soviet Union, that consists of repeated exposures to 5-7 minutes of steady or progressive hypoxia, interrupted by equal periods of recovery. It has been proposed for training in sports, to acclimatize to high altitude, and to treat a variety of clinical conditions, spanning from coronary heart disease to Cesarean delivery. Some of these results may originate by the different effects of continuous vs. intermittent hypoxia (IH), which can be obtained by manipulating the repetition rate, the duration and the intensity of the hypoxic stimulus...
2001: Advances in Experimental Medicine and Biology
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