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https://www.readbyqxmd.com/read/29159595/resilience-and-physical-and-mental-well-being-in-adults-with-and-without-hiv
#1
Jennifer A McGowan, James Brown, Fiona C Lampe, Marc Lipman, Colette Smith, Alison Rodger
Resilience has been related to improved physical and mental health, and is thought to improve with age. No studies have explored the relationship between resilience, ageing with HIV, and well-being. A cross sectional observational study performed on UK HIV positive (N = 195) and HIV negative adults (N = 130). Associations of both age and 'time diagnosed with HIV' with resilience (RS-14) were assessed, and the association of resilience with depression, anxiety symptoms (PHQ-9 and GAD-7), and problems with activities of daily living (ADLs) (Euroqol 5D-3L)...
November 20, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/29157214/segmental-ischaemic-infarction-of-the-iris-after-autologous-fat-injection-into-the-lower-eyelid-tissue-a-case-report
#2
Jaeyoung Kim, Sa Kang Kim, Mee Kum Kim
BACKGROUND: Autologous fat injection is getting popular in cosmetic procedures, however, still has a risk of fat embolism. Herein, we report the first case of segmental ischaemic infarction of the iris, which occurred after autologous fat injection into the lower eyelid. CASE PRESENTATION: A 28-year-old Korean woman complained of the discolouration of the iris after the fat injection. Slit-lamp biomicroscopy revealed segmental depigmented atrophic iris with sectoral sphincter palsy...
November 21, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29156467/-diagnosis-and-therapy-of-iris-lesions
#3
Joel M Mor, Konrad R Koch, Ludwig M Heindl
The most common iris lesions are iris nevi, iris melanomas and iris pigment epithelium cysts. However, there is an abundance of rare differential diagnoses that have to be considered, including other melanocytic and non-melanocytic lesions. Diagnostic tools include the slit lamp examination, gonioscopy, tonometry, transillumination, ultrasound biomicroscopy (UBM), optical coherence tomography, fluorescein angiography and standardized photography-assisted documentation. The timely identification of malignant lesions (i...
November 20, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29156218/use-of-luminescent-gunshot-residues-markers-in-forensic-context-part-ii
#4
A M Arouca, M A M Lucena, R J Rossiter, M Talhavini, I T Weber
Gunshot residues (GSR) are important physical evidence in firearm-related crimes. Recently developed non-toxic ammunition, however, requires a new methodology for its characterization. To overcome this drawback, the introduction of noncommercial luminescent markers in ammunition was proposed. These markers, synthesized and added to the gunpowder, presented as a versatile tool for GSR analysis, since they require UV radiation alone to visualize the luminescent GSR (LGSR). This has opened up new perspectives for understanding GSR behavior at a crime scene...
November 6, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29155715/indoor-experimental-assessment-of-the-efficiency-and-irradiance-spot-of-the-achromatic-doublet-on-glass-adg-fresnel-lens-for-concentrating-photovoltaics
#5
Guido Vallerotto, Marta Victoria, Stephen Askins, Ignacio Antón, Gabriel Sala, Rebeca Herrero, César Domínguez
We present a method to characterize achromatic Fresnel lenses for photovoltaic applications. The achromatic doublet on glass (ADG) Fresnel lens is composed of two materials, a plastic and an elastomer, whose dispersion characteristics (refractive index variation with wavelength) are different. We first designed the lens geometry and then used ray-tracing simulation, based on the Monte Carlo method, to analyze its performance from the point of view of both optical efficiency and the maximum attainable concentration...
October 27, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29154536/caged-naloxone-synthesis-characterization-and-stability-of-3-o-4-5-dimethoxy-2-nitrophenyl-carboxymethyl-naloxone-cnv-nlx
#6
Anita H Lewin, Scott E Fix, Desong Zhong, Louise D Mayer, Jason P Burgess, Samuel Wayne Mascarella, P Anantha Reddy, Herbert H Seltzman, F Ivy Carroll
The photo-labile analog of the broad-spectrum opioid antagonist naloxone, 3-O-(4,5-dimethoxy-2-nitrophenyl)carboxymethyl naloxone (also referred to as "caged naloxone", 3-O-(α-carboxy-6-nitroveratryl)naloxone, CNV-NLX), has been found to be a valuable biochemical probe. While the synthesis of CNV-NLX is simple, its characterization is complicated by the fact that it is produced as a mixture of αR,5R 9R,13S,14S and αS,5R,9R,13S,14S diastereomers. Using long range and heteronuclear NMR correlations, the 1H and 13CNMR resonances of both diastereomers have been fully assigned, confirming the structures...
November 20, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/29154392/rapid-and-simple-detection-of-ureaplasma-species-from-vaginal-swab-samples-using-a-loop-mediated-isothermal-amplification-method
#7
Kazumasa Fuwa, Mitsuko Seki, Yoshiyasu Hirata, Itaru Yanagihara, Yukiko Nakura, Chika Takano, Kazumichi Kuroda, Satoshi Hayakawa
PROBLEM: Ureaplasma species occasionally cause chorioamnionitis and premature labor. We developed a novel assay employing a loop-mediated isothermal amplification (LAMP) method to detect Ureaplasma parvum and Ureaplasma urealyticum. METHOD OF STUDY: Loop-mediated isothermal amplification primers were designed to amplify Ureaplasma-specific ureaseB genes. Four U. parvum strains, 5 U. urealyticum strains and 14 reference bacterial species were evaluated. Forty-six vaginal swab samples were analyzed by LAMP, culture, and PCR...
November 20, 2017: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/29153846/surgical-management-of-neurological-manifestations-of-mucopolysaccharidosis-disorders
#8
REVIEW
Tord D Alden, Hernán Amartino, Amauri Dalla Corte, Christina Lampe, Paul R Harmatz, Leonardo Vedolin
The mucopolysaccharidosis (MPS) disorders are ultra-rare lysosomal storage disorders associated with progressive accumulation of glycosaminoglycans (GAGs) in cells and tissues throughout the body. Clinical manifestations and progression rates vary widely across and within the different types of MPS. Neurological symptoms occur frequently, and may result directly from brain damage caused by infiltration of GAGs, or develop secondary to somatic manifestations such as spinal cord compression, hydrocephalus, and peripheral nerve entrapment...
September 28, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/29153776/francisella-noatunensis-subspecies-noatunensis-clpb-deletion-mutant-impairs-development-of-francisellosis-in-a-zebrafish-model
#9
Elisabeth O Lampe, Carl Zingmark, Julia I Tandberg, Ida Marie P Thrane, Espen Brudal, Anders Sjöstedt, Hanne C Winther-Larsen
BACKGROUND: Francisella noatunensis ssp. noatunensis (F.n.n.) is the causative agent of francisellosis in Atlantic cod and constitutes one of the main challenges for future aquaculture on this species. A facultative intracellular bacterium like F.n.n. exert an immunologic challenge against which live attenuated vaccines in general are most effective. Thus, we constructed a deletion in the F.n.n. clpB gene as ΔclpB mutants are among the most promising vaccine candidates in human pathogenic Francisella...
November 16, 2017: Vaccine
https://www.readbyqxmd.com/read/29153456/association-of-mortality-with-ocular-diseases-and-visual-impairment-in-the-age-related-eye-disease-study-2-age-related-eye-disease-study-2-report-number-13
#10
Chandana Papudesu, Traci E Clemons, Elvira Agrón, Emily Y Chew
PURPOSE: To evaluate the association of mortality with visual acuity (VA) impairment, age-related macular degeneration (AMD), and cataract surgery. DESIGN: Cohort study. PARTICIPANTS: Participants with at least intermediate AMD enrolled in a randomized controlled clinical trial of lutein/zeaxanthin and/or omega-3 fatty acids, the Age-Related Eye Disease Study 2 (AREDS2), for treatment of AMD and cataract. METHODS: Baseline and annual eye examinations included best-corrected visual acuity (BCVA) assessments, slit-lamp examinations, and stereoscopic fundus photographs that were centrally graded for development of late AMD (central geographic atrophy or neovascular AMD) or pseudophakia...
November 16, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29152624/preparation-of-fe-mofs-by-microwave-assisted-ball-milling-for-reducing-cr-vi-in-wastewater
#11
Fu-Hua Wei, Ding Chen, Zhao Liang, Shuai-Qi Zhao, Yun Luo
Fe-Based metal-organic frameworks (Fe-MOFs) were prepared with trimesic acid and FeSO4·7H2O via a microwave-assisted ball milling approach. The structure and thermal stability of the as-prepared Fe-MOFs were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared spectrometry (FTIR), X-ray photoelectron spectroscopy (XPS), and thermogravimetric analysis (TGA). When used to degrade 20 mg L(-1) hexavalent chromium in aqueous solution, the Fe-MOFs were found to completely reduce a 100 mL solution within 120 min under natural light and a 400 mL solution within 90 min under Xe lamp irradiation...
November 20, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29151226/erratum-to-sequential-super-resolution-imaging-of-bacterial-regulatory-proteins-the-nucleoid-and-the-cell-membrane-in-single-fixed-e-coli-cells
#12
Christoph Spahn, Mathilda Glaesmann, Yunfeng Gao, Yong Hwee Foo, Marko Lampe, Linda J Kenney, Mike Heilemann
No abstract text is available yet for this article.
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29148703/bond-energy-driven-low-high-angle-grain-boundary-movement-mediated-porous-se-te-synthesis-for-water-splitting-reaction
#13
Anup Kumar Sasmal, Arpan Kumar Nayak, Prashant Kartikeya, Debabrata Pradhan, Tarasankar Pal
Herein, for the first time we applied metal-metal bond energy factor for the evolution of porous Se-Te alloy. Porous Se-Te material has been prepared from their elemental states only through heating-cooling process in silicone oil without using any reagent, surfactant or capping agent. Surprisingly the reaction occurred at much lower temperature (240 °C) than the m.p. (450 °C) of Te0. The nucleation and growth have been clarified by means of varied bond energy for the first time. Difference in bond energy between hetero metal-metal bond (Se-Te) and homo metal-metal (Se-Se) directs nucleation and growth towards the fabrication of porous structure even from their elemental state where low angle grain boundary (LAGB) and high angle grain boundary (HAGB) movements play their governing roles...
November 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29146584/microrna-tissue-atlas-of-the-malaria-mosquito-anopheles-gambiae
#14
Lena Lampe, Elena A Levashina
Anopheles gambiae mosquitoes transmit the human malaria parasite Plasmodium falciparum, which causes the majority of fatal malaria cases worldwide. The hematophagous life style defines the mosquito reproductive biology and is exploited by P. falciparum for its own sexual reproduction and transmission. The two main phases of the mosquito reproductive cycle, pre-vitellogenic (PV) and post-blood meal (PBM) shape its capacity to transmit malaria. Transition between these phases is tightly coordinated to ensure homeostasis between mosquito tissues and successful reproduction...
November 16, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29146334/impact-of-fluorescent-lighting-on-the-browning-potential-of-model-wine-solutions-containing-organic-acids-and-iron
#15
Paris Grant-Preece, Celia Barril, Leigh M Schmidtke, Andrew C Clark
Model wine solutions containing organic acids, individually or combined, and iron(III), were exposed to light from fluorescent lamps or stored in darkness for four hours. (-)-Epicatechin was then added, and the solutions incubated in darkness for 10days. Browning was monitored by UV-visible absorption spectrophotometry and UHPLC-DAD. The pre-irradiated solutions containing tartaric acid exhibited increased yellow/brown coloration compared to the dark controls mainly due to reaction of the tartaric acid photodegradation product glyoxylic acid with (-)-epicatechin to form xanthylium cation pigments...
March 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29145103/gold-chlorophyll-a-hybrid-nanoparticles-and-chlorophyll-a-cetyltrimethylammonium-chloride-self-assembled-suprastructures-as-novel-carriers-for-chlorophyll-a-delivery-in-water-medium-photoactivity-and-photostability
#16
Vito Rizzi, Davide Vurro, Tiziana Placido, Paola Fini, Andrea Petrella, Paola Semeraro, Pinalysa Cosma
The stability of Chlorophyll a in water during prolonged exposure, at room temperature, to a neon lamp has been investigated by means of UV-vis and fluorescence spectroscopies. In addition, the Chlorophyll a (photo)stability evaluation in presence of suitable carriers has been performed in order to investigate its reactivity under the same conditions, for possible and future applications in Antimicrobial Photodynamic Therapy. Cetyltrimethylammonium chloride was chosen to solubilize Chlorophyll a in water. While, cetyltrimethylammonium chloride-capped gold nanoparticles offer a great opportunity because combine the Chlorophyll a action, used as a photosensitizer in Antimicrobial Photodynamic Therapy, with gold nanoparticles effect used in photothermal therapy...
November 9, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29144726/physalis-mottle-virus-like-particles-as-nanocarriers-for-imaging-reagents-and-drugs
#17
Hema Masarapu, Bindi K Patel, Paul L Chariou, He Hu, Neetu M Gulati, Bradley L Carpenter, Reza A Ghiladi, Sourabh Shukla, Nicole F Steinmetz
Platform technologies based on plant virus nanoparticles (VNPs) and virus-like particles (VLPs) are attracting the attention of researchers and clinicians because the particles are biocompatible, biodegradable, noninfectious in mammals, and can readily be chemically and genetically engineered to carry imaging agents and drugs. When the Physalis mottle virus (PhMV) coat protein is expressed in Escherichia coli, the resulting VLPs are nearly identical to the viruses formed in vivo. Here, we isolated PhMV-derived VLPs from ClearColi cells and carried out external and internal surface modification with fluorophores using reactive lysine-N-hydroxysuccinimide ester and cysteine-maleimide chemistries, respectively...
November 16, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/29144379/a-digital-microfluidics-platform-for-loop-mediated-isothermal-amplification-detection
#18
Beatriz Jorge Coelho, Bruno Veigas, Hugo Águas, Elvira Fortunato, Rodrigo Martins, Pedro Viana Baptista, Rui Igreja
Digital microfluidics (DMF) arises as the next step in the fast-evolving field of operation platforms for molecular diagnostics. Moreover, isothermal schemes, such as loop-mediated isothermal amplification (LAMP), allow for further simplification of amplification protocols. Integrating DMF with LAMP will be at the core of a new generation of detection devices for effective molecular diagnostics at point-of-care (POC), providing simple, fast, and automated nucleic acid amplification with exceptional integration capabilities...
November 16, 2017: Sensors
https://www.readbyqxmd.com/read/29144181/the-prevalence-of-amblyopia-and-its-determinants-in-a-population-based-study
#19
Mohammad Faghihi, Hassan Hashemi, Payam Nabovati, Mohammad Saatchi, Abbasali Yekta, Shokoofeh Rafati, Hadi Ostadimoghaddam, Mehdi Khabazkhoob
PURPOSE: To determine the prevalence of amblyopia and its determinants in a population-based study in Mashhad County, Iran. METHODS: This cross-sectional, population-based study was conducted on the population of Mashhad County aged >1 year using randomized stratified cluster sampling. Examinations were performed after selection of the participants and their free transportation to the sampling site. The examinations included the measurement of uncorrected and corrected visual acuity, cycloplegic and non-cycloplegic refraction, cover testing, slit-lamp biomicroscopy, and ophthalmoscopy...
November 16, 2017: Strabismus
https://www.readbyqxmd.com/read/29144134/haloarene-linked-unsymmetrically-substituted-triarylethenes-small-aiegens-to-detect-nitroaromatics-and-volatile-organic-compounds
#20
Moghal Zubair Khalid Baig, Prabhat Kumar Sahu, Moloy Sarkar, Manab Chakravarty
Unsymmetrically substituted triarylalkenes as aggregation-induced emission-active fluorogens (AIEgens) are sporadically explored by different researchers. In this paper, naphthalene, biphenyl and haloarene-linked new triarylethenes are conveniently synthesized and presented as unsymmetrically substituted extensive π-conjugates to continue the discovery of small molecules as new AIEgens. Moreover, fluorophores attached to haloarenes are noteworthy but such compounds are barely investigated as AIEgens. The possible mechanism underlying this AIE-behavior has also been addressed by the support of experimental/theoretical outcomes...
November 16, 2017: Journal of Organic Chemistry
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