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https://www.readbyqxmd.com/read/28918504/autism-spectrum-disorders-and-disease-modeling-using-stem-cells
#1
REVIEW
Anita Brito, Fabiele Baldino Russo, Alysson Renato Muotri, Patricia Cristina Baleeiro Beltrão-Braga
Autism spectrum disorders (ASD) represent a variety of disorders characterized as complex lifelong neurodevelopment disabilities, which may affect the ability of communication and socialization, including typical comportments like repetitive and stereotyped behavior. Other comorbidities are usually present, such as echolalia, hypotonia, intellectual disability and difficulties in processing figured speech. Furthermore, some ASD individuals may present certain abilities, such as eidetic memory, outstanding musical or painting talents and special mathematical skills, among others...
September 16, 2017: Cell and Tissue Research
https://www.readbyqxmd.com/read/28918372/enhanced-visible-light-photocatalytic-nitrogen-fixation-over-semicrystalline-graphitic-carbon-nitride-oxygen-and-sulfur-co-doping-for-crystal-and-electronic-structure-modulation
#2
Xiangwen Feng, Huan Chen, Fang Jiang, Xin Wang
Oxygen and sulfur co-doped semicrystalline graphitic carbon nitride (HGCNOS) was synthesized by a one-pot hydrothermal method and applied in visible-light photocatalytic nitrogen fixation. Remarkably, HGCNOS exhibited a higher photocatalytic activity than pristine graphitic carbon nitride (GCN). Oxygen doping caused semicrystalline structure, making exciton dissociated at the order-disorder interfaces of HGCNOS and releasing more electrons and holes. Furthermore, the conduction band position of HGCNOS was elevated by sulfur doping, promoting the reduction ability of HGCNOS...
September 8, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28918336/total-and-cytosolic-concentrations-of-twenty-metals-metalloids-in-the-liver-of-brown-trout-salmo-trutta-linnaeus-1758-from-the-karstic-croatian-river-krka
#3
Zrinka Dragun, Vlatka Filipović Marijić, Nesrete Krasnići, Dušica Ivanković, Damir Valić, Jakov Žunić, Damir Kapetanović, Irena Vardić Smrzlić, Zuzana Redžović, Ivana Grgić, Marijana Erk
Total and cytosolic concentrations of twenty metals/metalloids in the liver of brown trout Salmo trutta (Linnaeus, 1758) were studied in the period from April 2015 to May 2016 at two sampling sites on Croatian river Krka, to establish if river water contamination with metals/metalloids downstream of Knin town has influenced metal bioaccumulation in S. trutta liver. Differences were observed between two sites, with higher concentrations of several elements (Ag, As, Ca, Co, Na, Se, Sr, V) found downstream of Knin town, whereas few others (Cd, Cs, Mo, Tl) were, unexpectedly, increased at the Krka River spring...
September 14, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28918313/learning-with-three-factors-modulating-hebbian-plasticity-with-errors
#4
REVIEW
Łukasz Kuśmierz, Takuya Isomura, Taro Toyoizumi
Synaptic plasticity is a central theme in neuroscience. A framework of three-factor learning rules provides a powerful abstraction, helping to navigate through the abundance of models of synaptic plasticity. It is well-known that the dopamine modulation of learning is related to reward, but theoretical models predict other functional roles of the modulatory third factor; it may encode errors for supervised learning, summary statistics of the population activity for unsupervised learning or attentional feedback...
September 14, 2017: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/28918295/case-report-primary-aortosigmoid-fistula-a-rare-cause-of-lower-gastrointestinal-bleeding
#5
Chirin Khalaf, Kim C Houlind
INTRODUCTION: A primary aortoenteric fistula (PAEF) is a communication between aorta and the gastrointestinal tract. It is a rare condition that is difficult to diagnose and therefore associated with a high mortality. PRESENTATION OF CASE: We report a rare case of a 66-year old man with an unstable bleeding PAEF. A salvage procedure was performed with a covered stent. Later, a sigmoidectomy was performed with resection of the fistula. Postoperatively, the patient suffered an infection that was treated well with antibiotics and he was discharged two weeks later with complete resolution of the fistula...
September 2, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28918256/transgene-is-specifically-and-functionally-expressed-in-retinal-inhibitory-interneurons-in-the-vgat-chr2-eyfp-mouse
#6
Guo-Zhong Xu, Ling-Jie Cui, Ai-Lin Liu, Wei Zhou, Xue Gong, Yong-Mei Zhong, Xiong-Li Yang, Shi-Jun Weng
Ectopic transgene expression in the retina has been reported in various transgenic mice, indicating the importance of characterizing retinal phenotypes. We examined transgene expression in the VGAT-ChR2-EYFP mouse retina by fluorescent immunohistochemistry and electrophysiology, with special emphasis on EYFP localization in retinal neuronal subtypes identified by specific markers. Strong EYFP signals were detected in both the inner and outer plexiform layers. In addition, the ChR2-EYFP fusion protein was also expressed in somata of the great majority of inhibitory interneurons, including horizontal cells and GABAergic and glycinergic amacrine cells...
September 13, 2017: Neuroscience
https://www.readbyqxmd.com/read/28918237/preface-to-the-special-issue-on-gaucher-disease-2017
#7
EDITORIAL
Ari Zimran, Jeff Szer
No abstract text is available yet for this article.
September 8, 2017: Blood Cells, Molecules & Diseases
https://www.readbyqxmd.com/read/28918199/psychosocial-barriers-to-healthcare-use-among-individuals-with-diabetes-mellitus-a-systematic-review
#8
REVIEW
Andrea Paduch, Silke Kuske, Tim Schiereck, Sigrid Droste, Adrian Loerbroks, Monica Sørensen, Marina Maggini, Andrea Icks
PURPOSE: To conduct a systematic review regarding psychosocial barriers to healthcare use in individuals with diabetes mellitus, using a well-established model of health-service use as a theoretical framework. METHODS: We used database-specific controlled vocabularies and additional free text terms, and conducted searches via MEDLINE, EMBASE, PsycINFO, CINAHL, Web of Science, OVID Journals. Included studies were rated according to the UK National Institute for Health and Care Excellence (NICE) criteria...
September 13, 2017: Primary Care Diabetes
https://www.readbyqxmd.com/read/28918094/post-acute-care-for-children-with-special-health-care-needs
#9
Charles D Phillips, Chau Truong, Hye-Chung Kum, Obioma Nwaiwu, Robert Ohsfeldt
BACKGROUND: Almost all studies of post-acute care (PAC) focus on older persons, frequently those suffering from chronic health problems. Some research is available on PAC for the pediatric population in general. However, very few studies focus on PAC services for children with special health care needs (SHCN). OBJECTIVE: To investigate factors affecting the provision of PAC to children with SHCN. METHODS: Pooled cross-sectional data from Texas Department of State Health Services hospital discharge database from 2011-2014 were analyzed...
September 8, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/28917950/suicide-behavior-and-associated-psychosocial-factors-among-adolescents-in-campeche-mexico
#10
Catalina González-Forteza, Carlos E Juárez-López, Alberto Jiménez, Liliana Montejo-León, Ulises R Rodríguez-Santisbón, Fernando A Wagner
Suicide is an important public health problem that requires a preventive approach. The present study aimed at assessing suicidal behaviors and their relations with other psychosocial factors in Campeche, Mexico, in order to inform the design of potential preventive interventions. A multistage probability sample of 2386 students representative of all middle schools of the state of Campeche, Mexico, took a standardized, paper-and-pencil survey covering selected psychosocial constructs including suicide behavior, depression, drug use, familial relationships, locus of control, impulsivity, and self-esteem, among others...
September 13, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28917859/superhydrophilic-graphene-oxide-electrospun-cellulose-nanofiber-hybrid-membrane-for-high-efficiency-oil-water-separation
#11
Chenghong Ao, Wei Yuan, Jiangqi Zhao, Xu He, Xiaofang Zhang, Qingye Li, Tian Xia, Wei Zhang, Canhui Lu
Inspired from fishscales, membranes with special surface wettability have been applied widely for the treatment of oily waste water. Herein, a novel superhydrophilic graphene oxide (GO)@electrospun cellulose nanofiber (CNF) membrane was successfully fabricated. This membrane exhibited a high separation efficiency, excellent antifouling properties, as well as a high flux for the gravity-driven oil/water separation. Moreover, the GO@CNF membrane was capable to effectively separate oil/water mixtures in a broad pH range or with a high concentration of salt, suggesting that this membrane was quite promising for future real-world practice in oil spill cleanup and oily wastewater treatment...
November 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28917740/switchable-zipper-like-thermoresponsive-molecularly-imprinted-polymers-for-selective-recognition-and-extraction-of-estradiol
#12
Huihuang Xiong, Xiaqing Wu, Wenhui Lu, Junqing Fu, Hailong Peng, Jinhua Li, Xiaoyan Wang, Hua Xiong, Lingxin Chen
Zipper-like thermoresponsive molecularly imprinted polymers (MIPs) were prepared based on interpolymer complexation via the synergy of dual functional monomers of acrylamide (AAm) and 2-acrylamide-2-methyl propanesulfonic acid (AMPS) for selective recognition and extraction of estradiol (E2) by temperature regulation. The resulting E2-MIPs attained controlled adsorption and release of E2 in response to temperature change, with higher adsorption capacity (8.78mg/g) and stronger selectivity (imprinting factor was 3...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28917714/mitochondria-in-the-nervous-system-from-health-to-disease-part-i
#13
EDITORIAL
Brian M Polster, Maria Teresa Carrì, Philip M Beart
In Part I of this Special Issue on "Mitochondria in the Nervous System: From Health to Disease", the editors bring together contributions from experts in brain mitochondrial research to provide an up-to-date overview of mitochondrial functioning in physiology and pathology. The issue provides cutting edge reviews on classical areas of mitochondrial biology that include energy substrate utilization, calcium handling, mitochondria-endoplasmic reticulum communication, and cell death regulation. Additional reviews and original research articles touch upon key mitochondrial defects seen across multiple neurodegenerative conditions, including fragmentation, loss of respiratory capacity, calcium overload, elevated reactive oxygen species generation, perturbed NAD(+) metabolism, altered protein acetylation, and compromised mitophagy...
September 13, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28917491/strengths-and-challenges-of-the-alaska-wic-breastfeeding-peer-counselor-program-a%C3%A2-qualitative-study-of-program-implementation
#14
Katie Cueva, Sarah Shimer, Dana Kent, Alan C Geller, K Viswanath, Teresa T Fung
OBJECTIVE: To explore the implementation of a breastfeeding (BF) peer counselor (BFPC) program with Alaska Special Supplemental Nutrition Program for Women, Infants, and Children (WIC). METHODS: The study used focus groups, surveys, and interviews, with transcripts analyzed in Atlas.ti and survey data summarized in Microsoft Excel. RESULTS: Respondents included 33 interviewed WIC staff and BFPCs, 25 clients in focus groups, and 129 surveyed clients...
September 13, 2017: Journal of Nutrition Education and Behavior
https://www.readbyqxmd.com/read/28917377/the-effect-of-a-beeswax-olive-oil-and-alkanna-tinctoria-l-tausch-mixture-on-burn-injuries-an-experimental-study-with-a-control-group
#15
Kenan Gümüş, Zeynep Karaman Özlü
OBJECTIVES: This study was planned to investigate the effect of a mixture of beeswax, olive oil and A. Tinctoria (L.) Tausch on burn wounds to determine the impact on burn healing, pain during dressing changes and duration of hospital stay. METHODS: The study was conducted between May 2014 and August 2015 in the Burn Unit of Ataturk University Research Hospital. The sample of this experimental study consisted of 64 patients (31 experimental group and 33 control group) who met its inclusion criteria...
October 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28917251/advances-in-external-beam-stereotactic-body-radiotherapy-principle-concerns-in-implementing-a-liver-radiation-program
#16
Stewart Gaede, Michael I Lock
Despite significant advances in diagnosis, surgery and medical oncology, patients with primary and secondary liver cancer have some of the worst prognoses in oncology. In addition, the incidence of liver cancer is expected to increase. For this reason, centres are seeking new treatments and establishing specialized multidisciplinary teams. This article will focus on the evidence and practical data to assist in setting up or improving current process pathways, to provide an efficient and safe radiotherapy program for liver...
September 2017: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/28917250/emerging-technologies-in-stereotactic-body-radiotherapy
#17
Lijun Ma, Lei Wang, Chia-Lin Tseng, Arjun Sahgal
Stereotactic body radiation therapy (SBRT) stems from the initial developments of intra-cranial stereotactic radiosurgery (SRS). Despite similarity in their names and clinical goals of delivering a sufficiently high tumoricidal dose, maximal sparing of the surrounding normal tissues and a short treatment course, SBRT technologies have transformed from the early days of body frame-based treatments with X-ray verification to primarily image-guided procedures with cone-beam CT or stereoscopic X-ray systems and non-rigid body immo-bilization...
September 2017: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/28917071/quantitative-evaluation-of-palatal-bone-thickness-for-the-placement-of-orthodontic-miniscrews-in-adults-with-different-facial-types
#18
Yunji Wang, Ye Qiu, Henglang Liu, Jinlong He, Xiaoping Fan
To quantitatively evaluate palatal bone thickness in adults with different facial types using cone beam computed tomography (CBCT).  Methods: The CBCT volumetric data of 123 adults (mean age, 26.8 years) collected between August  2014 and August 2016 was retrospectively studied. The subjects were divided into a low-angle group (39 subjects), a normal-angle group (48 subjects) and a high-angle group (36 subjects) based on facial types assigned by cephalometric radiography. The thickness of the palatal bone was assessed at designated points...
October 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28917020/predicting-opportunities-to-increase-utilization-of-laparoscopy-for-rectal-cancer
#19
Deborah S Keller, Jiejing Qiu, Anthony J Senagore
BACKGROUND: Despite proven safety and efficacy, rates of laparoscopy for rectal cancer in the US are low. With reports of inferiority with laparoscopy compared to open surgery, and movements to develop accredited centers, investigating utilization and predictors of laparoscopy are warranted. Our goal was to evaluate current utilization and identify factors impacting use of laparoscopic surgery for rectal cancer. METHODS: The Premier™ Hospital Database was reviewed for elective inpatient rectal cancer resections (1/1/2010-6/30/2015)...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28916976/preoperative-risk-factors-for-postoperative-complications-in-endoscopic-pituitary-surgery-a-systematic-review
#20
REVIEW
Daniel J Lobatto, Friso de Vries, Amir H Zamanipoor Najafabadi, Alberto M Pereira, Wilco C Peul, Thea P M Vliet Vlieland, Nienke R Biermasz, Wouter R van Furth
BACKGROUND: The ability to preoperatively predict postoperative complication risks is valuable for individual counseling and (post)operative planning, e.g. to select low-risk patients eligible for short stay surgery or those with higher risks requiring special attention. These risks however, are not well established in pituitary surgery. METHODS: We conducted a systematic review of associations between preoperative characteristics and postoperative complications of endoscopic transsphenoidal surgery according to the PRISMA guidelines...
September 15, 2017: Pituitary
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