Travis J Kochan, Sophia H Nozick, Aliki Valdes, Sumitra D Mitra, Bettina H Cheung, Marine Lebrun-Corbin, Rachel L Medernach, Madeleine B Vessely, Jori O Mills, Christopher M R Axline, Julia A Nelson, Ethan M VanGosen, Timothy J Ward, Egon A Ozer, David van Duin, Liang Chen, Barry N Kreiswirth, S Wesley Long, James M Musser, Zackery P Bulman, Richard G Wunderink, Alan R Hauser
Klebsiella pneumoniae has been classified into two types, classical K. pneumoniae (cKP) and hypervirulent K. pneumoniae (hvKP). cKP isolates are highly diverse and important causes of nosocomial infections; they include globally disseminated antibiotic-resistant clones. hvKP isolates are sensitive to most antibiotics but are highly virulent, causing community-acquired infections in healthy individuals. The virulence phenotype of hvKP is associated with pathogenicity loci responsible for siderophore and hypermucoid capsule production...
December 2, 2023: Nature Communications